Conserved Protein Domain Family
Sre

?
pfam03125: Sre 
C. elegans Sre G protein-coupled chemoreceptor
Caenorhabditis elegans Sre proteins are candidate chemosensory receptors. There are four main recognized groups of such receptors: Odr-10, Sra, Sro, and Srg. Sre (this family), Sra pfam02117 and Srb pfam02175 comprise the Sra group. All of the above receptors are thought to be G protein-coupled seven transmembrane domain proteins. The existence of several different chemosensory receptors underlies the fact that in spite of having only 20-30 chemosensory neurones, C. elegans detects hundreds of different chemicals, with the ability to discern individual chemicals among combinations.
Statistics
?
PSSM-Id: 251743
Aligned: 19 rows
Threshold Bit Score: 236.834
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
Q9U2J1   1 MIFLIANl----TTICWPIYILQNFKlveFPGLLLSVLDFLLFFLTFYFAFRCAYLLVKVRVFHKNLSVLAVLLIFQWLE 76  Caenorhabditis elegans
O62488   1 MIIKNMDastnvPYLWLPIFLYDEPI---LASQVIASIELILYSICLYIVVVSLKIFVQVRMFHLNFIILVAPFFGIWFE 77  Caenorhabditis elegans
Q9XWH6   1 MIIAFLNs---tETLWIPVFSLNDRVyesPIYPFFAAIQILIYCSTAYIIVRTCKIITKIRLFHENKNILMAFFLCQWFE 77  Caenorhabditis elegans
Q9XUJ9   1 MNLLLTDd----IVIWIPIHEINNPAytnMNYLIFNVVYLLLLFISAYFTVILVMTSWRIRKFHKNMTICFSFYFGAWFE 76  Caenorhabditis elegans
Q9XUK3   1 MIFLIGNss--yFRVLTPTTVLHDHRlrgFPDNIYLIVYGIFHLLIMYFVLKCAYICLKIRVFHWNLTCLIFSCSVQWFE 78  Caenorhabditis elegans
Q9U2J4   1 MIFLIGNst-nkIKICYPIYMLYNFEllkFPSIILLVSEFMMFVVTVYFAIRCVFVICKVRAFHKNLTGLAIVMTVQWLE 79  Caenorhabditis elegans
Q9XV41   1 MAIFIRN------SHQMPSNAG--VF----VQAVLFLLSFVCTVVGVKIALKFT-------IFHKNQRNIFIALLLLWFE 61  Caenorhabditis elegans
O61898   2 LLLHYFN------LSHFQVNDHFYPH-----MRNFLYGETAFYVADTINMMFYIWVLFSAQQFHFNFTLVSGTQYVIHFF 70  Caenorhabditis elegans
Q9U2L5   2 LSIDQFN------ERAFNKN------------GCYVYFLIVFLIIIILNIFS--------LMYYFFNLAITVRVKYYKTN 55  Caenorhabditis elegans
Q21142   2 CSQSTYN------VRFITFVNTSYIQ----AENLENVFDSLLKFEIAVLAFSWL------EFLYVFYLLIFIRAMHFNLT 65  Caenorhabditis elegans
Q9U2J1  77 VLIGKIISWPYETGYWt-LEELTeksllNSTMQQWWTENPSEMIKVDSFNHDVLFFIAGFLKIHFG-LSMSNILLIVSVE 154 Caenorhabditis elegans
O62488  78 LIIGKLITMCYQLSIFs-IGNLE-----IRKFYVLWTDDSNKMLVVNSFEGLELLIIAGFMEYHYM-FSVVFGAVAVAIE 150 Caenorhabditis elegans
Q9XWH6  78 AILAKILILPYQIGLIq-IGNSP-----GKSYFSWWSSGRNDMVLVESTDDIRVLYIACYVYRHYM-FSMFFGIMAIGVE 150 Caenorhabditis elegans
Q9XUJ9  77 CWLGLVLVWPYKNGLVlvEDTHM-------KFTNFETSDRTIMAHITKYPETTCLLFGSFLIWHYLaST-VAGMCNFVIE 148 Caenorhabditis elegans
Q9XUK3  79 TFIGSLMILPYESGYWi-LGESN------ITIQQGWTDIESEMIKVPNFFNLF--FLGSFLKFHYI-LSMGTTGLLLAVE 148 Caenorhabditis elegans
Q9U2J4  80 ALVAKFISWPYETGYWv-LEGayntslsNTTLKQFWTDNEAEMIQIQNFTYDLSFFVAGFLKLHFA-ISASNILFVISIE 157 Caenorhabditis elegans
Q9XV41  62 LLICRILLWAFKYSLAi-EISKA---------IDCDDECHHLGRCSFEKNKFDPIFISAIMRYHYM-FFVLATPVGILVE 130 Caenorhabditis elegans
O61898  71 DNLAIIVMRLHSLLGFt--------------------DDFD--------IGSNVVFNGAMTFSVYCiVAAMCSLPFSILE 122 Caenorhabditis elegans
Q9U2L5  56 LQIIHQAIYATCPFSSv-ILIIE---------KIFDVMEK-S---EVLTSDSSLFMYKQYFRTAIM-CPPLFALTAIMLE 120 Caenorhabditis elegans
Q21142  66 FLFINYGGQYFGSMLSr-CVIIY---------MQLYPDKN-----LEYIIPLANFARTVCLFI------AMYILPIFMVE 124 Caenorhabditis elegans
Q9U2J1 155 RSCASYFLEDYENKSRTWIALLIIFFSQTFTMIFS--IVFFFNYLS-YVFGISIIAISNIGAVMLMLYSRHYNQKITKIH 231 Caenorhabditis elegans
O62488 151 RLAASVLIDNYESTNKIFIPIALTVFFQIIAITCS--CLALFHKFT-IITINGTWIVSCACSSIVFFLVERINLRWKAEM 227 Caenorhabditis elegans
Q9XWH6 151 RACATFYIHDYEHVRRRHIPVILIILVNIITIPYV--YFVIHNRIP-FLVVYGQWAVCIVLSTSAYATILRINFVFR-NQ 226 Caenorhabditis elegans
Q9XUJ9 149 RAIASFFFSDYEKKQRSYLGYTLLATSQCCCIQGSilVFFYFFSLKpVLIISTILLSCVILT---FFLLLQYNTSLRNRL 225 Caenorhabditis elegans
Q9XUK3 149 RTFACYYLTDYEKKPRIHLVVILIIGHQTFNFISA--ILHFFQILQnLVYIVLIALIPNVVSSVIFAVTENYNQKVTKTI 226 Caenorhabditis elegans
Q9U2J4 158 RCCACYFLNDYEKKSRTWIAVTLVISAQIFNFVVA--YLFYVRYVE-FLFMFIVAATPNVLAVTLILFARQYNLKITRIH 234 Caenorhabditis elegans
Q9XV41 131 RIFATVFVKDYEKESRYWIFgLIFFSQNMFACTMS--VFTTTMGAT-FHFIILTILGSLSGSAVIYALVEYFNQRRLTKL 207 Caenorhabditis elegans
O61898 123 RCFATRYLKDYEANSRAYISYALVFLLNFIGIIGA---ILLQNKNN-TIFVVAFLMILNLFALLTNQFLRTWNLKKYEEC 198 Caenorhabditis elegans
Q9U2L5 121 RIFATWFIKDYEQKQRHYIAYGIIALMTFISMLTA--YVFNSTNL--IFAYVGAHFLLNIVCYIVSIITYRINRNWYNDN 196 Caenorhabditis elegans
Q21142 125 RCLATFLVANYEKSRKIWVSLIILSIFHPLVFASA--FAYIQCWLP-VVFHVISFFVVNIIGYVGVQICFLYNTKRYKLF 201 Caenorhabditis elegans
Q9U2J1 232 EDYA-Hq--S--NYTLAARFQAKENMKCFEMIWKIVIFALCIGIVGFATALSLYFHI-----LPeldT-MLNLVMQAMIN 300 Caenorhabditis elegans
O62488 228 EHPR-Re--K--VYTISQRFQVKENIRALDLGKRLIFSELGTISIIGLIIATLLLEL-----VP---P-SLVHIAENALF 293 Caenorhabditis elegans
Q9XWH6 227 MRKN-ItdhE--KYSLARKFQVEENIRSLKLAKYTVLVGSVHISLTLLVFTCLMLGF-----FErlqV-FFVHILENLIL 297 Caenorhabditis elegans
Q9XUJ9 226 DLKQi----El-SYSLAARFQAAENARSLKLAVFVFAVICCIFVLAISTMGILFLQL-----LPdyyDvAIMTIFECLVS 295 Caenorhabditis elegans
Q9XUK3 227 ENFA-Np----nNYTLAARYQAKENVKCFAMIKKVIFAGIGMIFISCSSILLIYFDV-----FPnhvD-LLNFVFEASLN 295 Caenorhabditis elegans
Q9U2J4 235 EKFA-RvsnY----TLAARFQAKENNRCFEMISKVLIAGFFIVCLGLLTAIFLFFNL-----FPqldT-VLNLCFIAVAN 303 Caenorhabditis elegans
Q9XV41 208 EN---Eh--RttNYTLSIRYQLKENLKTLKLMRQFFISIIVIIIAMGLANYLPILLKldedtILtvrT-YMDYIFHSNPV 281 Caenorhabditis elegans
O61898 199 HSNVsIrfqRggKYSLAKRFQISENIKSLHMLNFIILYMGFMNVCLVISVLFSSFDIs-----PerqA-ICSLALDASIF 272 Caenorhabditis elegans
Q9U2L5 197 Re-------NkhDYSLGTRFQISENIKVYKFFSHYLFVLAFFPFTCTACALFIQYDs-----SPlhrE-IMFVVFDLSFT 263 Caenorhabditis elegans
Q21142 202 S--Q-Kp--RmtTYGLSERFQLAENIKMCKVLKKVQGSILLFNVGCSSILLMDSFEv-----DIlitY-ASYVAFNFLAL 270 Caenorhabditis elegans
Q9U2J1 301 LPPLVVCPAIIYSVESFRSYHFLSVTYFWEk--LKVG-HGAVDMMPVqKKSFSVKHDEIrKETETYFNQLAASWI 372 Caenorhabditis elegans
O62488 294 LNPFGICTVAMYSIPAWKKRYKNAFPSIFC---FLMR-LKNRKIDVQsMEPLEEFSKRIyEETNIHFAQLNESWT 364 Caenorhabditis elegans
Q9XWH6 298 LPALVMAVALLCCSVAWRHEFMQKLP------------VLGKHISGTsRIGISESRRSVvLESEVYFQQLRSSWN 360 Caenorhabditis elegans
Q9XUJ9 296 LNPLFIVPAAMFSVPEWKIAFYKHMPFVG-----------RRHRHRNpDSKIMDHDLRVsMETNLYFVQLEDAWR 359 Caenorhabditis elegans
Q9XUK3 296 VGPSFIGPTLIHSVDAWRNYELCPFSN-------KIVaVARKTTIVKvVPVECDKDSELrKETDTYFRQLNNSWS 363 Caenorhabditis elegans
Q9U2J4 304 LPPLVICPAIIYSVDAFRNHPFLSISSIWE---KLT---GASAIMPVrK-GSTAKCEELkKETETYFNQLAASWT 371 Caenorhabditis elegans
Q9XV41 282 FLVPTAIFTIEHYRKYVLKKVKLGLGMRHEsrkMDTRkLRPQIATKEiDTFFEIFVKQLeGSPRKMQSGSFKRNK 356 Caenorhabditis elegans
O61898 273 FYSFAIPQIMTCFCHKWKVQTNTFRIRIGC--------LRTGKVNLEpLRDTFGGDMRGsVSMNRYFDQLQDSWE 339 Caenorhabditis elegans
Q9U2L5 264 LLCILAPYLILKTNEPWQNDLEQILSKAGIlraSKVEtILERSKTLKnTFGEAMEFETSqHS-DMYFNQLQKSWN 337 Caenorhabditis elegans
Q21142 271 VYGITIPIIVHVVLPEWQKESRRLIHTCFCrskNAIQqAPKSTFGERmIY-KDHAQEAN-----IYFDQFNKATN 339 Caenorhabditis elegans
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap