Conserved Protein Domain Family
DUF4347

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pfam14252: DUF4347 
Domain of unknown function (DUF4347)
This domain family is found in bacteria and eukaryotes, and is approximately 160 amino acids in length. There are two completely conserved residues (C and G) that may be functionally important.
Statistics
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PSSM-Id: 433811
Aligned: 111 rows
Threshold Bit Score: 111.458
Created: 25-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_012174041     142 VVVIDPAVVD----TNHLLTAIdgsrqdaRIiNlagnadlpadtsagslLDIYLLDGS---RDGVAQLTDIL----ENYD 210   Desulfosu...
XP_008993412     302 VILISSRIPA----YEMVVESV-------KS-G----------------VISVVYEHSvtlESLLYLIEKAL----DGQK 349  
jgi:Desal_1674   110 VLVASSGLAD----VDDLLGAA-------KE-N----------------VVTVTYDGD---TDNPDDIFNRIesalDGKQ 158  
jgi:Mmc1_0421     66 VLLVASNVAD----GDDLAAAA-------QE-G----------------VVVVRYDAF---NDSGAAILEKIaqalDGRE 114  
Q89L34             7 VVFIDSRVSD----IDALLDGL-------AP-D----------------EQAFVLNGA---SDGFAQIATIL----KNNG 51    Bradyrhiz...
jgi:Mnod_2545     23 VAFIDPGLDA----VEVLRAGL-------RR-E----------------IEPILLEAS---SPAPLQIAQAL----RGRA 67   
CCD04008           4 VIIADAGLED----LDGLLSRR-------HP-D----------------VRVMLVSAA---DDAHAVLAEAL----AARP 48   
Q3AR79             3 IILADALIDD----VALLLSSL-------PA-A----------------TTCYLLHAQ---DDAVKVIQTAF----QQPN 47    Chlorobiu...
Q30U04            11 LIFIDAHLEE----IDTLCANL--------PhD----------------AEIQLLNSE---ENLLIQIAAQL----KNRN 55    Sulfurimo...
BAJ00515          84 LIIIDPAVHDpymlYQALNAKFrqhlgqnSK------------------TQIVFLRPE---LEPLQQILIAI----KDKP 138  
WP_012174041     211 --TLDAVHIFSHG-DTGAVYLGTT-PVTGENLAD----RQ--NDLTAWGAALA------PDGD--LLLYGCDVAAGDDGV 272   Desulfosu...
XP_008993412     350 ---AQSMGIFSDG-DSRDINLLQGyKIGVKNLLK--------PEVRDFWEKLGsyvateEEGG--HVDFFAPLGASEAGT 415  
jgi:Desal_1674   159 ---AASIGFASHSiGSGSIHLGGDySVDADTLLSnpemTEfwKNV---GSLVE------SDGH--IDLLGCGVADGEVGK 224  
jgi:Mmc1_0421    115 ---ADSIAFATHNaGTGALDITEAlPMDLASLAAngeaRAfwTEI---GTMLN------QDGH--IDLLGCEVAGSVQGD 180  
Q89L34            52 ltGLASISIVGHG-APGEIEIGSS-VIHDADLAN----DA--AALSAIGASLA------SDGA--LALYACDTAAGATGS 115   Bradyrhiz...
jgi:Mnod_2545     68 --DLDAIHILAHG-SPGSINFAAG-AVTADTVRD----HA--DELALVGRALG------EDGQ--LLVWSCHAGAGAEGA 129  
CCD04008          49 ----SALHLVAHG-EPGRVLLGAQ-PLDARSLLD---------------RSWP------DARGteIHIHACHAGAGEAGR 101  
Q3AR79            48 ----THLHFLGHG-EEGAITLGGK-TFTADDFIAlaptHS-------------------SSGA--IHFWSCKTGAGTKGV 100   Chlorobiu...
Q30U04            56 --DIAALHLITHG-RSGELLLGDN-GVFLETLPL----YG--KELLAITQAMS------SEGE--ILIYGCEVAFGERGS 117   Sulfurimo...
BAJ00515         139 --NLSQLSIISHA-SNGAIFLAGK-WIDKDYINQ----HK--AMMSEIGSSLK------KGAD--LKLYGCNLAAGLSGK 200  
WP_012174041     273 AFVETLAAFTG-ADVAAST-DRTGPVDLD-GNWDLEFQTGP-VET---PVLSNATTGYSHLL 327   Desulfosudis oleivorans
XP_008993412     416 EVLSQLSQLTG-TFFTAPTgIATGSYQHIlSDW-LGAQWGK-APSs-iYFSESKLQTWSSft 473  
jgi:Desal_1674   225 DFISKLEQITG-REIAASI-DDTGNVEAG-GNWLLE--EGG-VDLvelYFDSGKLGEFDGVL 280  
jgi:Mmc1_0421    181 MLVSLISDIAG-RAVAASD-DATGNAASG-GDWVLE--RGN-VDAattYFDGERLQDFTGLL 236  
Q89L34           116 QFISDLSAYAGgVTVDAAT-HVIGNADP--ASWTLDVSTTPaAAAvsaPFAEQALANFSTTL 174   Bradyrhizobium japonicum
jgi:Mnod_2545    130 ALTRALKAAGG-APVTVAQ-SLIGHAALG-GTWTISSDIAG-AAA---PLTPSAQEGYfava 184  
CCD04008         102 LLLDRLAAATG-AAVAASS-GLVGPAAQG-ASWTLDLSTAP-VGA---PSPFAAVEGWTHVL 156  
Q3AR79           101 AFVNSIAQAFN-TVVSACS-TLVGAAHKG-GSWRLDVHSNE-RVAvacPFGK--AAAYQHTL 156   Chlorobium chlorochromatii ...
Q30U04           118 AFVEMLRDITG-LKIAAST-HKVGSSELG-GSWELDNAHVNs------IVSPLVVSEFKGVL 170   Sulfurimonas denitrificans ...
BAJ00515         201 RFVNRVAELTQ-LDVAAST-DTTGGAKQG-HNWELEYKVGS-INSr-sLFSEALPTSYSSTL 257  
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