XP_001468426 170 KTITSTALRSALDHRTIDVHKSFLQEFTAVYQSYQRVAAQVNELQSKCSSLEDTLNTTagrpSREVEDFFYQIQAYQAEL 249 Leishmania in... XP_959603 76 VAENRRKLRLDLQKEVIDSNGEIIHEFGKVAEQLKRIGYTIGKLNESYNDMRTQIHAA----HASTASTLGEASQLMTQK 151 Neurospora cr... XP_751125 68 TAETRRQLRLDVQKEVVECNAEIVRDFGKVAEQLQRIGTVISSLNQTCEEMRQHIVRA----KQDTAPVIEEASALMNQK 143 Aspergillus f... XP_505497 38 TASIRRSLRANTEAEVIKANGEALKKFAPLVAQIQASGNTIADLNHKFTLMQQLVNTC----KNDTRHVVSEGSELMAQQ 113 Yarrowia lipo... XP_459774 145 S-NSRKKLRGEIENDLIKTQGLMLKEYQPVIKNLSNLENDLKNLNGLRDSITEKVNKD----FQSTKDLNGEVKNLNDTK 219 Debaryomyces ... XP_001384029 166 SM-SRKKLRGKVENELIKNQSLVLKEYQPVIKQLKVVEDRLSKLNDLNKVTNDNIENK----FKYSSEFNTKVKELNSEK 240 Pichia stipit... A6ZS37 193 TL-ARRALRTDLESQLLKEHITVLEEFKPIIRRIKRLSSSVEKIQRTSEKLLSNETNE----VPTNNVVLQEIDQYRLKA 267 Saccharomyces... XP_446427 187 TL-ARKSLRTDLETQLLKDHVTVLEDFKPIVRRIKRLAAPVQQIENIGEEILKNDKET----FSQKY--ISDIDDCRNHL 259 Candida glabr... XP_455261 150 TL-NRKSLRSKLENSMLNSHSDILSNFQSIARRIKRLSGPLERINNAMQNFKD-----------TTESIDFEFEHVKDRL 217 Kluyveromyces... Q75AZ8 170 SL-SRKTLRSQLEKELLKDHLATLENFQPIARRIMRLRQPVKNIQEISEKVLD-AQEA----QNKSPLQDPLVSEVREKL 243 Ashbya gossyp...
XP_001468426 250 QLVRSHDKEVDEFRKQHHFGAAEQQVL--EEGAVDMNFLNVLERARQVHQRSSELMQsQEYHQ-GALAVMESTYGAITRA 326 Leishmania in... XP_959603 152 RQIESKQKLLSTFKTHFILTQDEVDALtlTSEPVDDLFFTVLAKAKKISRDCEVLLG-FEDQT-LGLGIMEQVTRNLNHG 229 Neurospora cr... XP_751125 144 KESETKQQLLDAFVKHFIVSEDDLLVLtsAEEPIDDRFFNVLDRVKQVHHDCEVLLG-GENQR-LGLELMEKSSRNLNSA 221 Aspergillus f... XP_505497 114 ENISKKRDLLKRYTDAFVLTEREMDILkgNDEVPFETFKQVFIKAQKIHKDSEILLA-NDDTR-AGQITMYKANQALENA 191 Yarrowia lipo... XP_459774 220 SLINLKKGLLISFQNKFALDVYEEYVL--QNGEINDEFFQVLIKCEKIHENCSILLS-VDNPQ-LGLKIMSKFNQLINKS 295 Debaryomyces ... XP_001384029 241 RLINLKKNLLINFKAKFTLNEYEEFVLd--sGDINDEFFTVLKKAEEINANCSILLS-IENPQ-LGLKIMSKSNHLINRS 316 Pichia stipit... A6ZS37 268 EQLKLKKKILLSIRDRFTLNQVEDDVIt--NGTIDNIFFEVVKKVINIKDESSFLLT-LPNLN-AGNALIMGVNEILEKT 343 Saccharomyces... XP_446427 260 LKLEIKKKILKALQSKFTLNQLEDDLI--ENGPLKEEIFDIVDKLTKMKEHATYLLA-LPNSK-AGEVLIKQTNITLDTI 335 Candida glabr... XP_455261 218 DQLKARRQVIIKLRDSLTLTQLELDHL--QNGTINDLFFQILNKINFIKEKATYLLS-NEKTTsAGVALLKTMNNNLTVS 294 Kluyveromyces... Q75AZ8 244 EMLKLKKRVLVGIRESLTLNQLEDEQL--RNGEIEDSYLDVLDKMMEIKERSTYLIA-MNYEK-AGKALLGNINQYLQLA 319 Ashbya gossyp...
XP_001468426 327 TEKIARHL--------------LSTA-------GSG----EgrsagvaasaaaggagsiaADVP---------E----V- 367 Leishmania in... XP_959603 230 FQKLYRWI--------------QREF-------KSL----N-------------------LENP---------Q----I- 251 Neurospora cr... XP_751125 222 YQKLFRWI--------------QKKF-------KSL----N-------------------LEDP---------R----I- 243 Aspergillus f... XP_505497 192 NNTLIRDT--------------ETSL-------INYaqlgE-------------------TDNF---------K----Q- 217 Yarrowia lipo... XP_459774 296 VERIINFT--------------NKTL-------NNLy---S-------------------LNTT---------T----K- 318 Debaryomyces ... XP_001384029 317 VERIINFT--------------NKTL-------SNL----Y-------------------SLNS---------K----Ar 339 Pichia stipit... A6ZS37 344 NKKIFNYLidfly----sfessSNLL-------NDH----G-------------------TTEQ---------E----S- 375 Saccharomyces... XP_446427 336 NKKISNYLidymytfesnsnmgTKHV-------IDP----T-------------------ERN----------------- 368 Candida glabr... XP_455261 295 NKRIYNYL--------------INFI-------EEY----D-------------------TLSRqygertigdE----S- 325 Kluyveromyces... Q75AZ8 320 NKRIYNYL--------------LRFLydyeyntDTF----G-------------------ERNF---------EgdnvG- 352 Ashbya gossyp...
XP_001468426 368 TGFQLR----------CVRLLYEEsPSLHEKFLDEVARLRRASVLRRYFHLLTTGSanTstglyqsggqpsaydggvgsr 437 Leishmania in... XP_959603 252 GSAIRR----------ALRVLAER-PTLFQNCLDFFAEAREHVLSEAFYTALTGSSaaG--------------------- 299 Neurospora cr... XP_751125 244 SSSIRR----------ALRVLAER-PSLFHSCLDFFADARDYALSDAFHYALTDTVsgS--------------------- 291 Aspergillus f... XP_505497 218 DPQLRE----------RLSLLND---VNRAKTLGQFTETRRRQLLKSFTSALTENSqkN--------------------- 263 Yarrowia lipo... XP_459774 319 LTTLHQ----------CLKFLRKR-LNYFNTVIDNFVDTRSRLIIDEFLNQINGDLdkS--------------------- 366 Debaryomyces ... XP_001384029 340 LRTLHQ----------CMRYLKNK-LNYFSNVVNTFVDSRAKVLVDDFLSQIQGNLdsN--------------------- 387 Pichia stipit... A6ZS37 376 LNIFRK----------SLVFLSSD-LELFNELLKRVTTLRSKSILDEFLSQFDMNSt----------------------- 421 Saccharomyces... XP_446427 369 LALFQK----------GLVYLSND-IQYYDDFLKRVTTMRSKTLLDEFLSQFGTTSelS--------------------- 416 Candida glabr... XP_455261 326 LSNFQT----------SLIHLSND-VQFFQDFLNRIVGLRSKRLLDDFLSQFDIDNkkL--------------------- 373 Kluyveromyces... Q75AZ8 353 LSSFNAvwytcpptggTLMILSKG------------TSMRSKKLLDEFLIPFVIDNneG--------------------- 399 Ashbya gossyp...
XP_001468426 438 hgsseaG---------------M--G-------ARPLEAELNNPTYFFSSLCAWLHQTIAEEQDFIHNFF--------Vs 485 Leishmania in... XP_959603 300 ------Le-------------dP--S-------VKPIELVAHDPLRYVGDMLAWSHSAAVGEREALEVLFisegdeiaK- 350 Neurospora cr... XP_751125 292 ------G---------------GdrN-------VKPIEFSAHDPLRYVGDMLAWVHSTTVSEREALEALFvadgeeiaK- 342 Aspergillus f... XP_505497 264 ------G--------------------------TKALDFYAYDCQRYIGDILAWVYSCVVLETENTSILI--------G- 302 Yarrowia lipo... XP_459774 367 ------G---------------D--NrsgsiqhDRPIILSAHDPVRFIGDLLAYIHSVVVNETETISSIF--------G- 414 Debaryomyces ... XP_001384029 388 ------GnvstfkrrsssisseT--S-------SRPIYVSAHDPIRFIGDLLAYVHSLVVNESDTIISIF--------T- 443 Pichia stipit... A6ZS37 422 -------------------------T-------SKPIILSAHDPIRYIGDVLASVHSIIANEADFVKSLF--------D- 460 Saccharomyces... XP_446427 417 ------T-----------------------------TISSSEDPVRYIGDVLATIHTMIANEVDFVKSLF--------Kf 453 Candida glabr... XP_455261 374 ------Q---------------------------RPIILSAHDPVRYLGDVLAYVHSMIVNELEFLKSTF--------K- 411 Kluyveromyces... Q75AZ8 400 ----------------------------------RSIILSAHDPARYLGDVLAHVHSLLANEGDFLKSLF--------K- 436 Ashbya gossyp...
XP_001468426 486 d---epEVGQGGrrshattAA-----PSSAclqagsdaaraardkarqqALLEGVFGGVCKHIRAALDNVLER------- 550 Leishmania in... XP_959603 351 ------GIQVGR-------EA-----EVWRlvaedgeemnifdpvvalnQLVDRDMSGAVRILRQRVEQVIQTneetila 412 Neurospora cr... XP_751125 343 ------GIQAGL-------SS-----EPWSridegeevs--fdgrkalnDLVNRDLVGVSRALRQRIELVIQGhdepvtc 402 Aspergillus f... XP_505497 303 ------Qnd---------------------------------------sELVDNCTQSLCSPLRLRVERAVASqtrgpqi 337 Yarrowia lipo... XP_459774 415 ------ISKEEN-------ED-----DDIEykd-------------iidDVTGRILNSLSRSVKSKIEQVITSetklati 463 Debaryomyces ... XP_001384029 444 ------FETSE--------SE-----VEKKefet------------iikDIIDKILKSLVKPVKSKVTQIISAetklsts 492 Pichia stipit... A6ZS37 461 -----------F-------QD-----EDLKdtpisilqqnktflkgidnKLLNDIIQSLSNSCRIRIEQIVRFeenpiin 517 Saccharomyces... XP_446427 454 tsedmdKSSSMI-------IN-----NNAQyfdg------------ldlKLVNDIVQYLANSCKLRIEQVIRFeenkvin 509 Candida glabr... XP_455261 412 ------LKSELV-------TSdsvlkDNMDfigd------------lhlKLLNEIFTSLANTIRIRLEQIVRFennpmln 466 Kluyveromyces... Q75AZ8 437 -----------Y-------QE-----ERMAdmtqsifqknkdilqslhvNMLNDIMSTLSNSVRIRLEQIVRFeeeatvt 493 Ashbya gossyp...
XP_001468426 551 ---------------------------LGRTAAVLGAAtcsse---gegrASGCGSIaLSG-SA--DALAPrkgPRGLTG 597 Leishmania in... XP_959603 413 fklanlin----fykstfsrlvgpasiLVEAMGTLETEalrqfrslardhVATLQTEfQHT-PP---DLRP---PDFLTD 481 Neurospora cr... XP_751125 403 ykvvhlls----fyratfsrllgtksnLADMMQTLEKFtfsrfeslmleqVNTLSNDhAALtPP--DDLSA---PEFFLD 473 Aspergillus f... XP_505497 338 fkiaglve-----fyksmlskhlpnsqLVDTLTQLTAFcnthftktcesrVRNVSVSlPTT-LS--SDLQP---PEFLTQ 406 Yarrowia lipo... XP_459774 464 yaiyslvelytimfakhlkessndkhnLLMTVRELVSSsqnkiisiiqnkLTTIKSSnSAQ-LElnTDLQP---PEWIIE 539 Debaryomyces ... XP_001384029 493 ysifnlve----lysmmftkqlsdtseVSIALKSLVKAsqdrlasiisnrLASIRTSnSAQ-LElnLDLQP---PEWIIE 564 Pichia stipit... A6ZS37 518 feivrllkl---yrvmferkgiqddssIINNLKSLEDIsknriigyyedyMKQTVMAeTKN-SS--DDLLP---PEWLSE 588 Saccharomyces... XP_446427 510 feitqlldl---yssmfvnkgirddnpLVLHLIQLRDIsekkiinsltkqLAETENTqISS-P----DLLP---PQWLSD 578 Candida glabr... XP_455261 467 ldivqclsl---yqmmlvknginessqLMTSLNDLENLarskivssvtsyLKDLDKNqIAA-----ADLLP---PDWFVD 535 Kluyveromyces... Q75AZ8 494 fdisqllsl---yklmftkqgmlddnkLVKVFDDLAVLaktktmnyytefLSEAVKEePEV-----TDLLP---PKWLSK 562 Ashbya gossyp...
XP_001468426 598 GLTRLfMAATGRSPIAA----FRGAGHDEsnallqryagvttraqqeaVASSMLRPPLQGI----------QTCVtlvq- 662 Leishmania in... XP_959603 482 ALEQL-SAIMKTYETSLs---SSGDDPEAef---------------asIMAEAFDPFMAGC----------INMAnhatp 532 Neurospora cr... XP_751125 474 ALEEL-TSLMKTHDASL----EAEDAESEstaen----------kftpVLRVAFDPFLQLA----------KSSAaelpd 528 Aspergillus f... XP_505497 407 TLVDL-KEIL---EANQ----QYSLDEQVvr----------------kHIDNSLDPYMEFC----------RRVAsdgad 452 Yarrowia lipo... XP_459774 540 FYSDI-LPIID-QNTSD----TFMNLSTEnn---------------aeFMKMIINKPIEIF----------NEHIennis 588 Debaryomyces ... XP_001384029 565 FYSDL-LPILDQTTTDT----IFNF-TAEen---------------eeFMKLLVDEPIEIF----------FEHIgsnki 613 Pichia stipit... A6ZS37 589 YMNKL-VELFEIYEKTH----AAEDEESEdnkl-----------lsskNLQTIVEQPIKDV----------LLKQlqtsf 642 Saccharomyces... XP_446427 579 YLNSI-TELFDHVERLYggkrFSKDDIDSdkym-----------fpydTLKTVIEEPFMTS----------LIKQikdsy 636 Candida glabr... XP_455261 536 YLSKL-SQLLNK-----------LEQQNEtril------------tddLYDKLILDPINNNlvlnlqnwfpTAKKeksar 591 Kluyveromyces... Q75AZ8 563 YLSDL-TALFDKINGS-------SEQTGIvd---------------knFFTKLVKTPCEST----------FLKQaelcf 609 Ashbya gossyp...
XP_001468426 663 ------------------lfeyYTATTFAP-L--------L-G-------EDSALTRLIRKTAPQKTRELFQRLLHVLTA 707 Leishmania in... XP_959603 533 psks----------iflincfvAARTTLSG-F--------T-F-------VRKYAADIQTKIEEEKARLVIAQYELFRAE 585 Neurospora cr... XP_751125 529 atar---------aiyttnvllTARSTISA-Fa-------F-A-------SATHMDPISTALSSLRMELLEIQHRYLLDA 583 Aspergillus f... XP_505497 453 fdae----------ifllncldQIIITLKL-Y--------S-A-------SEYKVDSFQSSVDEIEQVLTERLFHKFVKQ 505 Yarrowia lipo... XP_459774 589 klfnrr-----dqvilklnfldLILSKIMPiI--------L-L-------SDKILE-LNDLTEKLSLELTNLQLDSLISG 646 Debaryomyces ... XP_001384029 614 feskkd------qlilkhnfldLILSKLLP-I--------TiV-------SDKVIE-INEMINTLTQELTQLQLEAILKE 670 Pichia stipit... A6ZS37 643 plakknekekaslltieincfdLIKSRLQP-F--------E-GlfaqdddSRKITIWVCDKLKEYTKQMLTLQIKFLFEN 712 Saccharomyces... XP_446427 637 plakkkeeirivmltlqincfeMINFRLQP-YslsifsydE-S-------CKHILENIQHTLDETVEKLQKLQISLLFER 707 Candida glabr... XP_455261 592 idll----------ivqinsfdLVKSKLGP-Fhsti-fssD-Y-------GKSVFSKLETQYTLCVTKLKETMNSYLFES 651 Kluyveromyces... Q75AZ8 610 plakkdrrvkfdllvleingldMIVSRLGP-Yrtni-fsdE-Y-------GSEVYDSLKRSLDTLLGQLEVHQTRNILES 679 Ashbya gossyp...
XP_001468426 708 HLLDSTAGI-------------------------IGrtatlR---RLASSHALKQAADGDDAQGV-------Splaaerr 752 Leishmania in... XP_959603 586 SGLDSLIEA-------------------------LDgl-diR---KKDDVGKVATLEEVQPEALR-------Q------- 622 Neurospora cr... XP_751125 584 SGLGVLLTAlepfapsptiskpesegkdghappqVD-----K---QPTDIAEIADLPAFQPEALI-------A------- 641 Aspergillus f... XP_505497 506 VGLGE----------------------------------------------------DLEPAHLS-------E------- 519 Yarrowia lipo... XP_459774 647 CQLTNFYNI-------------------------IN-----MicpFSDDFFDVSIYQPITENKLF-------Sedn-iia 688 Debaryomyces ... XP_001384029 671 CGLYDYYNI-------------------------VN-----MicpFSDDFFDTSIYEPIKENQLY-------Nkse-llk 712 Pichia stipit... A6ZS37 713 TGLDLYSNL-------------------------VNmifpvD---SVKDELDYDMYLALRDNSLM-------Eldmvrkn 757 Saccharomyces... XP_446427 708 TGLNMYYNL-------------------------MNmifpiD---SIQDEIDYDMYMSLVDNPLM-------Slenlekn 752 Candida glabr... XP_455261 652 TGMELYFNL-------------------------FNmifpiI---SVQDELDYDMYLSAVENPIMklavihdN------- 696 Kluyveromyces... Q75AZ8 680 TGLELYYNL-------------------------FNmifpvA---SVQDPLDYDMYLSAQENQIMkletietN------- 724 Ashbya gossyp...
XP_001468426 753 AVTKTGPSTFVLDFLVtftygnD-A-NSL-GGAPNGSESALLNDSESDIYMSFSSLSAAAA------------------- 810 Leishmania in... XP_959603 623 SSQKLDDFLPSALIDA------T-E-KLK-NLQDSKLASSVIEEAAERFCVDFEHVEEMLL------------------- 674 Neurospora cr... XP_751125 642 VGQQLDDFLPSALMDA------T-D-NLK-HLQSASFVQSVTEEAVEAFCRDFEFVEGMIIgadeargrvhikrmedgsd 712 Aspergillus f... XP_505497 520 ISFQLDDFLPSALTDL------H-S-MLF-RISSPVIVDNIARNSTKKFVEEFSKLEGKVK------------------- 571 Yarrowia lipo... XP_459774 689 ANDIIQNFLPSALLDI------Q-Q-SLF-KVNSPMIVNNIITNSSLEFIKFYLKFNLIIN------------------- 740 Debaryomyces ... XP_001384029 713 INEIIQSYIPNALLDI------Q-S-SLL-KLNPPSIVNEVTTNASLEFVKYYGKLSQI--------------------- 762 Pichia stipit... A6ZS37 758 VHDKLNYYLPQALTDV------QgN-LLF-KLTSPMIADEICDECFKKLSLFYNIFRKLLI------------------- 810 Saccharomyces... XP_446427 753 IHEKLNDYLPQALPDF------Q-D-NLLiKLTSPSIADDVCEICFRTLTDFYCIFRRILK------------------- 805 Candida glabr... XP_455261 697 IHEKLNTYLPLAVSDF------Q-DvKLF-NLMPPAVEEDIVSTCFGNFIKFYKVFKSVLN------------------- 749 Kluyveromyces... Q75AZ8 725 IAQKLSDYLPKALLDVq-----D-T-WLL-YLASPKFADDIASRSFHVFANFYVVFKSVLL------------------- 777 Ashbya gossyp...
XP_001468426 811 ---------------TTR-FRQAN--------------DGQLLHHSAHDLRRVL 834 Leishmania infantum JPCM5 XP_959603 675 ---------------SAD-ELEEQrrveedgdeehsqsFRALFPRTSSEIRVLL 712 Neurospora crassa OR74A XP_751125 713 agvqddvatesgkvsDGD-EQESK--------------LRRLFPRTTGEIRVLL 751 Aspergillus fumigatus Af293 XP_505497 572 ---------------DTY-KVESD--------------YRQFFPRTTEDVELLL 595 Yarrowia lipolytica CLIB122 XP_459774 741 ---------------EYL--------------------DDASLIWSDIEVATLL 759 Debaryomyces hansenii CBS767 XP_001384029 763 ---------------NSA-FLQET------------------FTWSDFEIATLL 782 Pichia stipitis CBS 6054 A6ZS37 811 ---------------HLY-------------------------PNKKDQVFEIL 824 Saccharomyces cerevisiae YJM789 XP_446427 806 ---------------HLYpDNKEK--------------VEAILNFTESEFKTLa 830 Candida glabrata CBS 138 XP_455261 750 ---------------KIYpEDEEM--------------IMSTLNFTTNEVSTLL 774 Kluyveromyces lactis NRRL Y-1140 Q75AZ8 778 ---------------NIFpDDHQR--------------INSIFIYSEEEVKMLL 802 Ashbya gossypii ATCC 10895
Jiyao W et al.(2023). "The conserved domain database in 2023.",