Conserved Protein Domain Family
DUF3846

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pfam12957: DUF3846 
Domain of unknown function (DUF3846)
A family of uncharacterized proteins found by clustering human gut metagenomic sequences. This domain is found associated with an pfam07275 like domain. This suggests that this family may also be involved in evading host restriction.
Statistics
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PSSM-Id: 432899
Aligned: 29 rows
Threshold Bit Score: 83.4489
Created: 24-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
jgi:Shel_20190      6 VLVPVGDM-PRIVEVE------TYKDIQRYVGGNIEPCsWV--FDDAPSVYVNEEGKFTCRP-N-RAIYAtdkdagkvtw 74 
CCX65830            7 LALPVYRE-PYITNIEn-----SLENMQRFVGGYIEAVtVL--KNPQVILVCDEEGLLKGRAvN-PSIPDseky------ 71 
jgi:Franean1_6747   5 LVVPADSTkPYRQEEMnp---aDLQGLQRIVGGFIEPV--N--LTPGGSLYANDEGIMKGLPvNeRATALagfhth---- 73 
jgi:Shel_20470      5 LLIPVDDA-PRPVDVD------GLRDLQRLVGGDIEAVgWV--FDDAPTIYVNESGKFDGLPpN-RAIFAehpgtrwdgs 74 
CBK97813            4 LVFDTENR-MQFKDFGe----pLLDSLQKEVGGYIEVV-HPkyLPEGLCMVVDDEGRLKGSAiNni-------------- 63 
Q6AEU2             26 ILIDPHGG-ISNVWCSftsegqRQDWMRGHIGADLYGF-IS--LPEDIDVWVDDEGLYRGAPvN-VELTRmidkh----- 95  Leifsonia ...
jgi:Xcel_3457       8 VTIDVEGN-VQVTEWDaqgseqVSKHLQEAVGGWFDCVg----LSESLDMWVNDDGIALGLPvNvVATGIaarfg----- 77 
Q99Q41              8 LLITPEAD-IVPIDLPans-heRLTVMRSVIRCARVDV-VA--LTSQMDMWLDDEGIYNH-PvNkLASLLavrfg----- 76  Streptomyc...
jgi:Desgi_3545      8 LMVEPMKE-PYPSEVEn-----TLEGLQSAVGGYIETV--Y--LEDCAVLVCNEEGKLLGLPgN-RSLGNd--------- 67 
Q832A7              8 LVVEPGRP-PRPARVDy-----SLETFSQLVGGDLAMG-CF--LPQRVMLLYNEEANRQGLPpN-RCNpfv--------- 68  Enterococc...
jgi:Shel_20190     75 dgkkikegdlldILFGD------------FVCIGFDPEtgEDRDISDDE 111
CCX65830           72 --------grglVIVGD------------CFLCGVDGE--EFADLPDKW 98 
jgi:Franean1_6747  74 ------pftpgqLIVGD------------VYVTGPVDHhgLDTDVPNSi 104
jgi:Shel_20470     75 ---pirvgdlldVLYGP------------IVAVGFDPAtgEDRDINDAe 108
CBK97813           64 ----------asVLYGTpehgqpivgnavILREGFVAGerDFVSLTEDd 102
Q6AEU2             96 --------rpttPIHGN------------GLILGV-NQdgDVVSLTLDQ 123 Leifsonia xyli subsp. xyli
jgi:Xcel_3457      78 --------lthqPYWGP------------VVFTGGPDAdgASRPLgdlm 106
Q99Q41             77 --------fthqPYHGP------------VLLTGGADNdgETVPLTKDK 105 Streptomyces coelicolor
jgi:Desgi_3545     68 ------------IITGT------------FFVAGSNDDg-DFVSLTEDK 91 
Q832A7             69 ----------neCISGT------------FLLCGLSDGe-GFCSLSPAQ 94  Enterococcus faecalis
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