Conserved Protein Domain Family
DnaA_homol_Hda
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TIGR03420: DnaA_homol_Hda 
DnaA regulatory inactivator Hda
Members of this protein family are Hda (Homologous to DnaA). These proteins are about half the length of DnaA and homologous over length of Hda. In the model species Escherichia coli, the initiation of DNA replication requires DnaA bound to ATP rather than ADP; Hda helps facilitate the conversion of DnaA-ATP to DnaA-ADP. [DNA metabolism, DNA replication, recombination, and repair]
Links
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Statistics
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PSSM-Id: 274571
Aligned: 32 rows
Threshold Bit Score: 222.45
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
WP_011575274   4 QLSLAVNLRDTETFDSFIVG--ENLHLVHRLKS-L------LnktlnTK-NQ-PWLTFVSGDHGVGKSHLLYSLCHKAQS 72  Pseudoalteromon...
WP_011395815   8 QMALRLSNGESATLENFFEP--PSGVVVQSIQR-F------F-----TA-SE-DTVFSICGASAQGKTHLLMAACNGF-- 69  Hahella chejuensis
WP_011370470   4 QLPLKIGLREEVCFDTFIAEeeGVVLALNRFQQtL------L-----KS-NN-GDAFYFQGESGSGKTHILQAACRFMTE 70  Thiomicrospira ...
WP_004928855   3 QLQLDIEPQLDARISDFSGP--GWGHVVDAVRQ-L------------HA-GL-MNRFYIYGGAGSGKSHLLSAICDSYLE 65  Acinetobacter
WP_004083529   5 QLPLALRYSSDQRFETYLHA--PSG-LIAQLRA-V------V-----DQ-CS-RDWIYLVGASGSGKTHLALALCAAAEQ 67  Xylella fastidiosa
WP_011464796   3 QIALDIGLATGPTLSSFFAG--PNEAALRHLQI-WvagganA-----AA-RS-PVPTYFFGSAGSGKTHLLKAVQEAFRE 72  Albidiferax fer...
WP_011310735   3 QLLLDVRPPARPDLGHFVVG--RNAELMNQLAA-M------I-----EG-AAvERSVYVWGAPGTGKTYLLAAWARACEA 67  Thiobacillus de...
WP_012536829   6 QRILPLGVQAPATLEGYYPC--PNAAALHAVLK-L------V-----AE-PQ-GLCLYLYGPGGVGKSHLLLGAASALAG 69  Acidithiobacill...
WP_011288906  16 QLILDLLPESPPTLDNFVAG--GNAETLALLTE-W------L-----AGtRT-DTSFCLWGEAGSGRSHLLQASGFT--- 77  Dechloromonas a...
WP_010929163  19 QLLLDVLPAPAPTLNNYIAG--PNG---QALAA-A------H-----AL-TA-GRAIYLWGPAGCGRTHLLRGLSARPE- 78  Bordetella para...

WP_011575274  73 ANVSAVYLSFKDKQQYs-----PEVLDG---LEHSQLICLDDADALQDSQTWQIAVFDLLNRVKEL---GRsH--VVVCA 139 Pseudoalteromon...
WP_011395815  70 RSEKCFYLSLREYADFg-----VHVLAG---LESFDVLCFDDIDAIAGQPEWEEALFHLFNRCRER---GC-K--WLITS 135 Hahella chejuensis
WP_011370470  71 KKSSSVYLPLGDDSLPl----iPDVLNG---LEQTLLVCLDDVENIIGQPEWEHALASLLMRSKEL---GH-K--VVLSG 137 Thiomicrospira ...
WP_004928855  66 IGKSAIKVSLLELLDAp-----IEAITS---LERYDLVALDDIEAISGVPHWQKAVFHLINYNNEV---GG-Q--LVFSS 131 Acinetobacter
WP_004083529  68 VGQSVAYLPLQVAVGRl-----RDALEA---LEGCLLVVLDGLQAIVGMREDEIALFDFHNRARAA---GI-T--LLYTA 133 Xylella fastidiosa
WP_011464796  73 QGASVGWLDASVQQP----------PEF---DERWAAVLMDDVHFYNVVQ--QQAAFNWFINAQTW---QR-G--VLAAG 131 Albidiferax fer...
WP_011310735  68 RGLTVDY-------------------GA---QQPAQAVVADQLESWDADR--QHTGFATFNRVREA---GG-L--WLAAG 117 Thiobacillus de...
WP_012536829  70 W---TPYMDCGDVPQLfnrikdLEGFSS---LVAAPLLCLDNIEVWAGQRDKETFLFDLYNERMSN---GR-P--MLLAG 137 Acidithiobacill...
WP_011288906  78 ------YVDAAl----------DPALKT---APAAEQLAVDHVEALDE--TGQIALFNHFNRLKMA---SG-M--LLTAA 130 Dechloromonas a...
WP_010929163  79 ----AIYIDAARAAQSl-----RELAEAdstAPMPRLVAVDDVHRMDDAR--QAGLFALYNRWRESaatGR-AfaLAVSG 146 Bordetella para...

WP_011575274 140 NGGPTSLNLQLADLASRLAWGVSFTLASLSD-EGRCVALLTRARQRGLVMPEKVAMYLVNHWQRDMPSLMNTLDKLDQLS 218 Pseudoalteromon...
WP_011395815 136 AEAPSQTPFLLPDLKTRLAWGECVRLPELDE-VQRINVLDIKAANIGFRLSDEVKQYIMRRAPRDLSSLSLILERLDKAS 214 Hahella chejuensis
WP_011370470 138 TNPAGSWSIATTELTHAMMSVLPITLKPLTNkPDIVLAMQRHALKLGFELPLDVGNYLIKQFSTDLQELLSVLRILEQAT 217 Thiomicrospira ...
WP_004928855 132 RVAPIELRLELPDLQSRLTQAVSVKLPNGSLfADRQALILSTMSRRGLQFDPQILDYLLLHGPHQASLLLKTIAQLEKLL 211 Acinetobacter
WP_004083529 134 RAIPDGLGLTLPDLRSRVAQCIRIALPTLDD-VGRASVLRERAQRRGLMLDEAAIEWLLSRGDRDLGSLVMLLERLDRES 212 Xylella fastidiosa
WP_011464796 132 ELPPADLKLR-DDLRTRLGWGHVFQLQLLSE-PERRAVLRQAADARGLFLSDEVMDFMLTRFSRDLGNLMELLNLIDGYA 209 Albidiferax fer...
WP_011310735 118 SVPPAELPVT-PELRTRLGWGLVFQIHGLDD-AEKRAALVHHAETLGFRLDTQVADYLLNHTSRDMQSLLRVLEALDRLS 195 Thiobacillus de...
WP_012536829 138 RAAPRFLDWALPDWASRASACLQVALRLPDD-TERMAILQEMAQRRGLQIGVEAAHYLLRHHARDPRTLDGLLTILDAGS 216 Acidithiobacill...
WP_011288906 131 DQPPAHLALR-EDLRTRLGSGLICRLQPLSD-AEKAAALGAQAKERALKLTPELIDYLMRHAPRDMRTLSTIIVALDEYT 208 Dechloromonas a...
WP_010929163 147 DRAPMSLPLR-EDLRTRLGWDLVFRLDPLSD-ADKLAALTAQAAERGLQLAPEVINWMLTHHERDIRKLAALLDALDRYS 224 Bordetella para...

WP_011575274 219 LQQQRKLTIPFVKEALN 235 Pseudoalteromonas atlantica
WP_011395815 215 LVEKRPITVPFVKSVMN 231 Hahella chejuensis
WP_011370470 218 FVEKRRMTLPFVKQILT 234 Thiomicrospira crunogena
WP_004928855 212 KGEKTKLSNATLRQIYA 228 Acinetobacter
WP_004083529 213 LATKRRVTIPFLRHVLA 229 Xylella fastidiosa
WP_011464796 210 LQTKRAITIPLIKSMMD 226 Albidiferax ferrireducens
WP_011310735 196 LETRRAITLPLLRQLLA 212 Thiobacillus denitrificans
WP_012536829 217 WEHQREVTIPFIRLCLG 233 Acidithiobacillus ferrooxidans
WP_011288906 209 LEQKRPVTLPLLRELLN 225 Dechloromonas aromatica
WP_010929163 225 LATGRPITTPLLRAMLA 241 Bordetella parapertussis
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