4QQW


Conserved Protein Domain Family
Cas3

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COG1203: Cas3 
CRISPR-Cas type I system-associated endonuclease/helicase Cas3 [Defense mechanisms]
CRISPR-Cas type I system-associated endonuclease/helicase Cas3 is part of the Pathway/BioSystem: CRISPR-Cas system
Statistics
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PSSM-Id: 440816
Aligned: 357 rows
Threshold Bit Score: 202.234
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4QQW_A       231 VILADWLVSqedfllerltslpadgsasalrAHFets----------lrrI-----Psll----daaGlrpitvppatFT 291 
WP_012662915 176 LIFSDKYEAif-------------------kESFsekn--------------etcwEe---------Y----------LS 203 
WP_012580505 206 LITCDYLAT----------------------MEFmkgvk------fvpkiIddylkDii------lnN----------IS 241 
WP_041556492 243 LTAADYLAT----------------------HAYmtgrqv-----keagiFed--rHrv------eeM----------IG 277 
WP_014769137 229 LIISDYYAT----------------------AQFmnygnckelkyknfglVdddfrKtiy-----krF----------YE 271 
WP_006928015 250 LTAADYYAT----------------------TEYtidlav-----kdfgvFlvgekEkl------qnT----------FK 286 
WP_089610926 214 ITGCDYCAT----------------------EEFmtgqp-------vqpmViqnrgEdl------kqS----------YD 248 
WP_128752865 247 LVASDFYST----------------------SEFingnei-----kkfgtIkd--vDrf------ydI----------YK 281 
WP_083710989 250 LTASDYLAT----------------------AHYmndwvem---vtdfglLtediqKni------iaN----------AK 288 
WP_099325853 222 LISSDYFAT----------------------MEFktgqk------fnhdiLrneikEevfnnfhkvdE----------FE 263 
4QQW_A       292 ---------ESFphl-----------------------skPn----gLQAsLAK-Hlpc-------lctGPGlVLITAPM 327 
WP_012662915 204 rl------iKLIe--------------------------sKknkmasIRNqARN-Eildny----renrDKKiYIIEAPT 246 
WP_012580505 242 sskingnfnPYIdkkinkfrtm---------------kkeevfdlntLRSvITA-Kieek-----feksKKNvFFIEVPT 300 
WP_041556492 278 hlrn-ykhnRGIyeqldkfv-------------feypqekSgdhlnrLRTgMAV-Evirtv----rehsDDRlFYIEAPT 338 
WP_014769137 272 nq-----fdKELinkttsdfk-----------dfdelqekSnsnlnhLRNkLFI-EvrtnlqnelkknkSQNlFYIEAPT 334 
WP_006928015 287 tsk---synKDFykrqeyyls----------lpldklqkrNpenlntLRQkLMA-Etlnav----kqnkNEYvFYLEAPT 348 
WP_089610926 249 estl-vnsiRQFhkdp---------------------ktfRgtpinaLRNeIFI-Eseanl----kenpEAHiYYLEAPT 301 
WP_128752865 282 enkn-yksiRRYekcing----------------egikpyKdgdineLRSsMFL-Eaeknl----enhlNENiFYLEAPT 339 
WP_083710989 289 ilk---synKEVydaignnep----------vnpdnyitqSndnlnaLRRcIAM-Evvgnv----rkntGKRlFYIEAPT 350 
WP_099325853 264 in-----qkKEInfnvniskdrnslrnvniedikwsdnqkRkealnkIRS-ILNvVtennlenildeqsDIRtFFLNIPT 337 
4QQW_A       328 GEGKTEAAYHVADLLGKA-TGRPGRFLALPTMATADQMHTRLkeyaryrventDl----pR-SStLALLHSM---AWLNP 398 
WP_012662915 247 GIGKTFSALHLALEICRD-KNKKRIINALPMTSIIDQTYEEYg----------Lvi-----nDDdLLKFHHL---TRSKS 307 
WP_012580505 301 GGGKTNISLRLVRKLLEK-K--KKVFYVIPYVNIIEQSFDYFs----------Kfi-----pGEyITRYDHKy--IDIad 360 
WP_041556492 339 GGGKTNLSMLAVTELMAVhPEIQKVFYVFPYTTLITQTNQTLk----------Nalg---ltSTeLAELHSK---AGFNE 402 
WP_014769137 335 GAGKTNLSLMSVVEILKLdTSITKVFYIFPFTTLITQTYTSIk----------Kila---ldNAqIVQLHSK---AKYNQ 398 
WP_006928015 349 GSGKTNLSLAIAMELLQAhQYVNKILYVFPFTTLITQTAQSIk----------Etlq---vtNAqMVQLHSR---SGFHS 412 
WP_089610926 302 GAGKTNMAINLSLRVLEIdPQINNIFYIFPFNTLVEQTKDTLl----------Pff------gDqIAVVNSL---TPVVM 362 
WP_128752865 340 GSGKTNTSINLAFKMLKNnSNLNKIFYIFPFNTLVEQTKKSLn----------DifkgnkDiQNdITVVNSI---TPIKL 406 
WP_083710989 351 GGGKTNVSMLALAELLKTdQSIQKIFYVFPFTTLITQTYLSLv----------Dtlg---lmeSeIAEIHSK---APIQK 414 
WP_099325853 338 GGGKTNISLRLALKIMEK-REIKKLFYVFPFINLIEQSYEVLg----------Kfig-----lrnMARLDSRfidSsd-- 399 
4QQW_A       399 D---Ya--PADl---------P--GVSKvlsnlghrdpfaatdWLMg--RKRGLL-APWAVGTIDQALMAVLr-aKHNAL 458 
WP_012662915 308 YgssEg--DEKke------tnSlgRQ-Q----------------NDf--IAMSWSsDKVIVTTFNQLFNAFYsnkNRDLI 360 
WP_012580505 361 ---dEn--KEKsy-----------------------------------tQTLFLN-FPFVFTTHVGFFDMFFrkgKSDNF 399 
WP_041556492 403 Kt-eE---REDg------------LyAD---------------KKQdyiDRLFAL-FPVCVMSHVKFFDMLKtnrKEANY 450 
WP_014769137 399 Kq-eE---KEDg------------IyGE---------------DKKnflDNQFMN-YPMTLLSHVKFFDILTgisKDDNY 446 
WP_006928015 413 Kr-eE---VKDg------------QyGQ---------------QYQnyiDNLFVN-YPIILMTHIKFFDILKstqKENIY 460 
WP_089610926 363 Gg-dG---EKD----------------N---------------YEAawlDRLFNN-YPIVLTSHINFFNALFgcgRERCF 406 
WP_128752865 407 Id-eE---EDNklhlkgslkqEi----N---------------YERavlDRQFLH-YPIVLTTHVGFFSHLFgneREEVF 462 
WP_083710989 415 Rt--R---ERDi------------NeDS---------------DYKnylDALFMN-YPVTLLSHIRFFDVLKtnaKETNY 461 
WP_099325853 400 ---nEdnyEDD---------------TS---------------VFAnyvDNLFFN-KPVLFLSHVKFFDLFFrndKNSNY 445 
4QQW_A       459 RLFGLAGKVVVVDEAHAVDPYMQVLLEQLLRWL-GTLDVPVVLLSATLHHSIANSLv---------KAY-L-Egargrrw 526 
WP_012662915 361 KFWTLRDSVVILDEIQAVPRILIQDLIKTILYLsEHFNIDFVIMSATIPAIKNFIPs--------eKIA-E-L------- 423 
WP_012580505 400 NFYQIANSVIILDEVQAYNPKFWNTLSNIFYYLsKYLNTTIIIMSATLPDFTKFIEk--------eNFV-EnL------- 463 
WP_041556492 451 LLHRLANAVVVIDELQTYNPLLWDKMYYLIEHYaRFFQVRFILMSATLPKIGKLRIplke----rtgFV-D-L------- 517 
WP_014769137 447 IFHRLSNSIVIIDEIQTYSPDFWARIVYLLDMYaKNFNIKFIVMSATLPKIGKIIDs---------QFT-F-L------- 508 
WP_006928015 461 LLHRLANSIVIIDELQSYSPAEWDKIRFFISNFaYFFNIRFILMSATLPKLDALFLpesnqvplphNFI-S-L------- 531 
WP_089610926 407 PLLKLCNSVIILDEIQSYKNSIWREIITFLQGYaRQLNMKIIIMSATLPQLDLLLKtv------egKFV-S-L------- 471 
WP_128752865 463 PLVHLANSVVILDEIQSYRNDIWKEIILFLKKYtEILNIKIIIMSATLPKLDKLTDtk-------eEFV-S-L------- 526 
WP_083710989 462 LLHRFTNSVVIIDEIQSYSPKIWDKIVYFIVNYaRYFNMRFIIMSATLPKIGDIIDrke----lasDFV-Y-L------- 528 
WP_099325853 446 NFYQIANSVVIIDEIQAYKDTVWTEVAYMFDVIgRFLNTHFIVMSATLPRLDILTNs----------TFhQ-I------- 507 
4QQW_A       527 nrsepqpvsevsypgwlhvdarigkvtrssdVd-PLPiAttprKP--LEVRLVDvpV----KE-GALNrst------vlA 592 
WP_012662915 424 -------------------------------Ld-Nry-----fSm-dF-NNRYS--Lki---dtD-INtpe------slw 452 
WP_012580505 464 -------------------------------Tp-DVv-DhklfE-------RAS--Yv-------fLDkd--------iE 486 
WP_041556492 518 -------------------------------Lp-Q-A-Ksy-mQNpnF-AGRVE--FrfelFQ-EEIDmn-------dlA 551 
WP_014769137 509 -------------------------------Vs-N-K-Qry-fQNpnF-AKRVT--IdtnvKN---INkpe------eiY 541 
WP_006928015 532 -------------------------------Lk-N-P-Kqy-fQNpnF-KGRVQ--FdfslID-KITSie-------elA 565 
WP_089610926 472 -------------------------------Vk-D-P-Qky-yQHplF-KGRVH--LdfslLEkGKITie-------elK 506 
WP_128752865 527 -------------------------------Ie-N-K-Dky-fKNplF-KNRVK--PdyslLNvSENLwd-------rlK 561 
WP_083710989 529 -------------------------------Ia-D-K-Nky-fQNpnF-CNRVQ--FdyslLEwDKPDkn-------niS 563 
WP_099325853 508 -------------------------------IpeDTS-Skv-fKHevFN--RTR--Itp-dKKl-KINesndknrfdklV 548 
4QQW_A       593 KE-------LTPL----------VKQGGCAAIICTTVAEAQGVYDLLSQwfatlgedapDLYLLHSRFPNRQRTEITATI 655 
WP_012662915 453 SA-------ITiN----------YENVNSLLCVLNTKKLSLETYNELEHsid-----ssELFFLNTNFIPKHRSEIIRNI 510 
WP_012580505 487 EK-------ILEE----------VNKSKKTLVVVNTVKESYRMYENLKSki------dgEVYILNSTLLYVRKRELIDYI 543 
WP_041556492 552 DF-------VLGKsveyr-dkpgKNGTVHTIIEFITKKSAAEFYAFIQEkep----ffdEVFLLSGTILEPRRREIINEL 619 
WP_014769137 542 EL-------LIKGsenyqtletnDSKKVKTIIEFITKKGADEFYKHAKKyse----ifdEIFILSGTILEPRRKEIIDFI 610 
WP_006928015 566 DF-------VFDEceky---sfqNNGVVKGIIEFIFKKRAGEFYKLIKErfns---anyQIYLLSGTILEPRRKEIIAHI 632 
WP_089610926 507 DE-------VL------------RFKDKRVLVEFIKKKTAREFFELCKEe--------cHAVLLTGDDNGARREQIIKRI 559 
WP_128752865 562 EK-------LIEVa---------KSTDKNIAIEFITKKSAEKFYDELyhnke---lsgkKILLLTGDNNKFERNEIIKDV 622 
WP_083710989 564 NYlenlnivVFEKsrdyaetngkYPDSVFTIIEFIFKKTASDYYSISKAtneki-nffdEILLLSGTILEPRRRQIINKL 642 
WP_099325853 549 NR-------I-KK----------LNKENKILIVLNTVKDSFDIYIKIQKekti--seefEVYLLNSTIIEARKKDILIAC 608 
4QQW_A       656 VdlfgkeGaqsgrrptrgAVLVATQVVEQSLDLDVDLMISDLAPVSLLLQRAGRCWRHEHLGiinrpqwaKQP-ELVVLT 734 
WP_012662915 511 RnrlknnQk---------TLLVSTQVVEAGVDLDFDFGIREFAPLYSMIQTAGRVNREGTKt----------GaVLQVTN 571 
WP_012580505 544 Kkyn-keKp---------LVLVSTQSIEAGVDLDFDVGFRAFSLLDSIIQTMGRVNRNAR-L--------KSA-KLYLFD 603 
WP_041556492 620 KnplsrkKn---------ILLITTQVVEAGVDIDMDLGFKNISLIDSDEQLAGRVNRNACK---------VGC-EVYLFR 680 
WP_014769137 611 Knt--hdKn---------ILLVTTQVVEAGVDIDMDIGFKEKSLVDSDEQLAGRINRNSSK---------EGN-KLFLFS 669 
WP_006928015 633 KksiekkSsa-------kILLITTQVVEAGVDIDMDIGFKDRSLIDSDEQLAGRVNRNART---------IPA-KVFLFK 695 
WP_089610926 560 Nn----gEk---------MVLIATQVIEAGVNIDMEIGFKDISLPDAEEQFLGRINRSCLNT--------SGA-VAYFFD 617 
WP_128752865 623 Nd----eNn---------IILVSTQIIEAGLDVDMYAGFKDISILDSEEQFMGRINRSCLK---------KMA-VVYFFD 679 
WP_083710989 643 KlgetrkKk---------ILLVTTQVVEAGVDIDMDLGFKDKSIVDSEEQLAGRINRNVNK---------PAC-KLYIFD 703 
WP_099325853 609 Kda---nRk---------IVLVSTQSVEAGVDIDFDVGFRAYAPFDSIVQVAGRINRNSGKE--------C-C-EMFVFE 666 
4QQW_A       735 PEqngdadrapwfprswtSVYpl--alLQrTYTl--LRRrngapvQIPeD---VqQLVD--DVYDDdsl--aedLEADM- 802 
WP_012662915 572 KIg--------------fSPYhgndllKKeVSEl--FQs------QME-Ene-ilPILK--KYFQMaier-------tpp 618 
WP_012580505 604 DGnw-------------kRIYks-----deREKi--LEEnfs---------kfKsGKLKlnEFYSLtiekl-----kkkl 649 
WP_041556492 681 LDna-------------sVLYgkd-krYQmVREq--ISvg-------eyErilReKDFG--CLYELvfekinwmNEQTYv 735 
WP_014769137 670 IGkgn-----------dkFVYkkd-krNGlSGKy--QEdg-------keQnvlNtKDFD--KFYSQildkiienNTKNFm 726 
WP_006928015 696 LDra-------------yAIYgkd-lrYAlTRDh--ISqe-------qyQkilQeKRFE--ILYQQvcdyinreNKNEFi 750 
WP_089610926 618 LDne-------------eVIYrgd-arLRySVRdv------------aiRrkvEeKRFD--EIYAQvfadliakTSMANk 669 
WP_128752865 680 LDka-------------sTVYkkd-yrKDsSVTl---Kqg-------yiRdilEnKDFD--KFYEIimrrieenLNRENp 733 
WP_083710989 704 CNte-------------kTLYggd-drYSlMKNikd-----------eyYeilEqKDFD--RLYRIviqkikekNHSEFi 756 
WP_099325853 667 DDas-------------eKVYgkd-lkSReTNKeafF-Sk---------KtidEnSELQ--EFYKRvingidqkNKMSFv 720 
4QQW_A       803 ER-MGE-EL 809 
WP_012662915 619 DPi----LL 623 
WP_012580505 650 NAfTLD-YL 657 
WP_041556492 736 QN-FRSgFL 743 
WP_014769137 727 EN-LKS-YI 733 
WP_006928015 751 RG-LKS-YL 757 
WP_089610926 670 MN-LAY-LD 676 
WP_128752865 734 DN-IKN-FR 740 
WP_083710989 757 EN-IDD-LF 763 
WP_099325853 721 DS-SQT-NI 727 
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