Conserved Protein Domain Family
secA

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PRK12906: secA 
preprotein translocase subunit SecA; Reviewed
Links
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Statistics
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PSSM-Id: 237260
Aligned: 24 rows
Threshold Bit Score: 1310.47
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
94985162    1 MFRVLNKVFDTNQRDVQRIVKtVVQPVNALEEETMKI--ENLAEAFMRLRQRVQEgGESLDDVLVPAFALIREAGRRAIG 78  
33519622    4 TLKLFKKLFRNRNERILVHMKkIVDMINYMEKDMEKLndNQLSNKTNEFRMQIKS-GINIEELLPQAFAVVRESVKRIFN 82  
116494436   1 MANILRKWVESDKREIARLGK-IADKVQQYEDEYAALsdEQLKANTPKLKDRLAA-GATLDDILPEAFATAREGAKRVLG 78  
161579493   1 MFRVLNKVFDNNKRDVERIIQtVVKPVNALEEETMRV--ENLAEAFMDLRRRVQDgGESLDSLIVPAFALIREAGRRSIG 78  
191637820   1 MANILRKWVESDKREIARLGK-IADKVQQYEDEYAALsdEQLKANTPKLKDRLAA-GATLDDILPEAFATAREGAKRVLG 78  
226356705   1 MFRVLNKVFDNNQRDVQRIIKtVVDPVNALEQETMQI--EDLAAAFLDLRRRVQEgGESLDDVLVPAFALIREAGRRSIG 78  
258539139   1 MANILRKWVESDKREIGRLGK-IADQVQRYEDEYAALsdDQLKANTQKFKDRLAA-GATLDDILPEAFATAREGAKRVLG 78  
258507894   1 MANILRKWVESDKREIGRLGK-IADQVQRYEDEYAALsdDQLKANTQKFKDRLAA-GATLDDILPEAFATAREGAKRVLG 78  
301065946   1 MANILRKWVESDKREIARLGK-IADKVQQYEDEYAALsdEQLKANTPKLKDRLAA-GATLDDILPEAFATAREGAKRVLG 78  
297623055   1 MLGFFQKMFDNNERDVRRIEReVVAAVNALEPAMEEV--EDLAAEYAKLRQRYED-GESLNALMPEAFALTRESAIRQLG 77  
94985162   79 KRHYDVQLIGGTALHQGRIAEMRTGEGKTLVATLALALNALEGKGAHLVTVNDYLARVGAEEMGLLYRTLGLSVGLITRD 158 
33519622   83 IRLFDVQMLGGIVLNNRCIAEMRTGEGKTLTATLPAYLNALTGKGVHIVTVNNYLAHRDATYNQPLFEFLGLNVGINLPG 162 
116494436  79 LFPFRVQIIGGIVLHEGNIAEMKTGEGKTLTATMPVYLNALTGKGVHVVTVNEYLSTRDATEMGELYNWLGLSVGLNLNS 158 
161579493  79 KRHYDTQLIGGAALHQGRIAEMRTGEGKTLVATLALAFNALEGKGCHLVTVNDYLARVGMEEMGLLYRTLGLTVGLANRE 158 
191637820  79 LFPFRVQIIGGIVLHEGNIAEMKTGEGKTLTATMPVYLNALTGKGVHVVTVNEYLSTRDATEMGELYNWLGLSVGLNLNS 158 
226356705  79 KRHYDVQLIGGAALHQGRIAEMRTGEGKTLVATLALSLNALEGRGCHLVTVNDYLARVGMEEMGLLYRTLGLTVGLASRE 158 
258539139  79 LFPFRVQIIGGIVLHEGNIAEMKTGEGKTLTATMPVYLNALTGKGVHVVTVNEYLSTRDATEMGELYNWLGLSVGLNLNS 158 
258507894  79 LFPFRVQIIGGIVLHEGNIAEMKTGEGKTLTATMPVYLNALTGKGVHVVTVNEYLSTRDATEMGELYNWLGLSVGLNLNS 158 
301065946  79 LFPFRVQIIGGIVLHEGNIAEMKTGEGKTLTATMPVYLNALTGKGVHVVTVNEYLSTRDATEMGELYNWLGLSVGLNLNS 158 
297623055  78 LRHYNVQLIGGAALHYGKIAEMKTGEGKTLVATLALVLNAIPGKGAHLVTTNDYLARTGAEWMGPVYRALGLSVGVIQHD 157 
94985162  159 MQPHQRQAAYACDITYVTNSELGFDYLRDNMAQSREQLVLRadnPLHYAIVDEVDSILIDEARTPLIISGAAEKATDLYY 238 
33519622  163 QTVCAKKIAYESDITYGTNNEYGFDYLRDNMVFNVKEQVQR---ELHYALIDEVDSILIDEARTPLIISGPSDDASLSYL 239 
116494436 159 KNSDEKREAYNCDITYSTNSELGFDYLRDNMVVYKEQMVQR---PLNFAIVDEVDSILIDEARTPLIISGGAEKTTGLYI 235 
161579493 159 LSPAEKQAAYACDITYVTNSELGFDYLRDNMAQSKEALVLRadtPLHYAIVDEVDSILIDEARTPLIISGAAEKATDLYY 238 
191637820 159 KNSDEKREAYNCDITYSTNSELGFDYLRDNMVVYKEQMVQR---PLNFAIVDEVDSILIDEARTPLIISGGAEKTTGLYI 235 
226356705 159 MQPHEKQAAYACDITYVTNSELGFDYLRDNMAQSREALAMRaehPLNYAIVDEVDSILIDEARTPLIISGAAEKATDLYY 238 
258539139 159 KNSDEKREAYNCDITYSTNSELGFDYLRDNMVVYKEQMVQR---PLNFAIVDEVDSILIDEARTPLIISGGAEKTTGLYI 235 
258507894 159 KNSDEKREAYNCDITYSTNSELGFDYLRDNMVVYKEQMVQR---PLNFAIVDEVDSILIDEARTPLIISGGAEKTTGLYI 235 
301065946 159 KNSDEKREAYNCDITYSTNSELGFDYLRDNMVVYKEQMVQR---PLNFAIVDEVDSILIDEARTPLIISGGAEKTTGLYI 235 
297623055 158 LRPDARRAAYACDITYMTNSELGFDYLRDNMAFRPEQLVLRadtPLNYAIIDEVDSILIDEARTPLIISGPAELATDKYY 237 
94985162  239 VYAKLVKRLQRGEpAEPGKRTEPTGDYTIDEKGKQVHLTEQGIAKIERLL-------SLGDLYSPENMDKAHMITQAIRA 311 
33519622  240 KINELVCNIIKRN-IDHCKYPEKEEYFTVDEKSRQVVLTEIGLILIEKLLiesgmmgMGESLYSSDNIILLHHVNSALRA 318 
116494436 236 RADRFVKTLKAET------------DYKIDWPTKTISLTESGIRKAEKNF-------GLDNLYDTENTALTHHIDQALRA 296 
161579493 239 VFAKLIRRLQKGEpAEPGVRTEPTGDYTIEEKSKAVHLTEQGITKIERLL-------SLKDLYSPENMDKAHMITQAIRA 311 
191637820 236 RADRFVKTLKAET------------DYKIDWPTKTISLTESGIRKAEKNF-------GLDNLYDTENTALTHHIDQALRA 296 
226356705 239 VYAKLIRRLQKGEpAEPGVRAEPTGDYTIDEKGKQVHITEAGISKIERLL-------SIPDLYSPENMDKAHMITQAIRA 311 
258539139 236 RADRFVKTLKADT------------DYKIDWPTKTISLTESGIRKAEKNF-------GLDNLYDTENTALTHHIDQALRA 296 
258507894 236 RADRFVKTLKADT------------DYKIDWPTKTISLTESGIRKAEKNF-------GLDNLYDTENTALTHHIDQALRA 296 
301065946 236 RADRFVKTLKAET------------DYKIDWPTKTISLTESGIRKAEKNF-------GLDNLYDTENTALTHHIDQALRA 296 
297623055 238 VMAKIAAQLERGEpAE-GEDKPATGDFTADEKTKDIHLTEAGIAKAEKAL-------GVDDLFSSKNMELAHMLRQALRA 309 
94985162  312 RELYHREKDYIVNaEGEVVIIDEFTGRSMPGRRYGEGLHQAIEAKEGVKIENENQTLATITYQNFFRLYDKFAGMTGTAK 391 
33519622  319 HILFACEVDYIVK-NGEILIIDEHTGRVMPGRRWSDGLHQAIEAKERVRIQNENQTLASITFQNYFRLYEKLSGMTGTAS 397 
116494436 297 NYIMLKDIDYMVS-DGEVLIVDQFTGRAMEGRRYSDGLHQAIEAKEGVQIQDENKTMANITYQNFFRMYTKLAGMTGTAK 375 
161579493 312 RELYHREKDYIVNaEGEVVIVDEFTGRSMPGRRYGEGLHQAIEAKEGVKIENENQTLATITYQNFFRLYDKFAGMTGTAK 391 
191637820 297 NYIMLKDIDYMVS-DGEVLIVDQFTGRAMEGRRYSDGLHQAIEAKEGVQIQDENKTMANITYQNFFRMYTKLAGMTGTAK 375 
226356705 312 KELYHREKDYIINaDGEVIIIDEFTGRSMPGRRYGEGLHQAIEAKENVKIENENQTLATITYQNFFRLYNKFAGMTGTAK 391 
258539139 297 NYIMLKDIDYMVS-NGEVLIVDQFTGRAMEGRRYSDGLHQAIEAKEGVQIQDENKTMANITYQNFFRMYTKLAGMTGTAK 375 
258507894 297 NYIMLKDIDYMVS-NGEVLIVDQFTGRAMEGRRYSDGLHQAIEAKEGVQIQDENKTMANITYQNFFRMYTKLAGMTGTAK 375 
301065946 297 NYIMLKDIDYMVS-DGEVLIVDQFTGRAMEGRRYSDGLHQAIEAKEGVQIQDENKTMANITYQNFFRMYTKLAGMTGTAK 375 
297623055 310 RVHYHRDKQYVKDeRGQIVIVDEFTGRLMPGRRFGEGLHQAIEAKEGVKIERENQTLATITYQNFFKLYNKIAGMTGTAK 389 
94985162  392 TEEKEFLDIYGSDVLVIPTNKPVIRQDADDLVYRTRMGKYQAVVEEVKQMHATGRPILIGTASIDTSEQLSALLKQAGIR 471 
33519622  398 TESFEFKSIYKLDTVVIPTNQPMIRIDFPDVIYMTEIEKINAIVSDIKDCVNRKQPVLVGTVSIDKSEIISRALKKEGIL 477 
116494436 376 TEQEEFREIYNMEVISVPTNKPVIRVDSPDVLYPTLDAKFNAVVEDIKARHEKGQPMLIGTVAIESSERLSKQLDEAKIP 455 
161579493 392 TEEKEFLDIYGSDVLVIPTNKPVIRVDSDDLIYRTRMGKYAAVVGEVQEMHATGRPILIGTASIETSEQLSSLLQQAGVQ 471 
191637820 376 TEQEEFREIYNMEVISVPTNKPVIRVDSPDVLYPTLDAKFNAVVEDIKARHEKGQPMLIGTVAIESSERLSKQLDEAKIP 455 
226356705 392 TEEKEFLDIYGSDVLVIPTNRTILRKDSEDLVYRTKMGKYAAVVQEVAEMHATGRPVLIGTASIVTSEQLSDLLTQAGIR 471 
258539139 376 TEQEEFREIYNMEVISVPTNKPVIRVDSPDVLYPTLDAKFNAVVDDIKKRHKKGQPILVGTVAIESSERLSKQLDDEKIP 455 
258507894 376 TEQEEFREIYNMEVISVPTNKPVIRVDSPDVLYPTLDAKFNAVVDDIKKRHKKGQPILVGTVAIESSERLSKQLDDEKIP 455 
301065946 376 TEQEEFREIYNMEVISVPTNKPVIRVDSPDVLYPTLDAKFNAVVEDIKARHEKGQPMLIGTVAIESSERLSKQLDEAKIP 455 
297623055 390 TEEKEFQEIYGADVLTIPTNRPVIRKDYDDIVYRTEKGKFEAVVREIEEVHKTGQPILVGTVTIDASEKLSAMLRRRGIK 469 
94985162  472 HSVLNAKYEAQEASIIAQAGRSGTVTIATNMAGRGTDIMLGGNaefilgeaieqnfgisrftpeaeafikaigredpeav 551 
33519622  478 HKVLNAKIHAAEADIIAQAGYPGAVTIATNMAGRGTDIVLGGNwrseiaalrnantha---------------------- 535 
116494436 456 HTVLNAKNHFKEAEIIMNAGQRGAVTIATNMAGRGTDIKLGPG------------------------------------- 498 
161579493 472 HAVLNAKFEAQEASIIAQAGRSGTVTIATNMAGRGTDIMLGGNdeyiigesieqqlgvsryapeveafikaisredpaae 551 
191637820 456 HTVLNAKNHFKEAEIIMNAGQRGAVTIATNMAGRGTDIKLGPG------------------------------------- 498 
226356705 472 HSVLNAKFEAQEASIVAQAGRSGTVTIATNMAGRGTDIMLGGNaefilgesieqhlgisrfapeaenfikaisrqdpaae 551 
258539139 456 HTVLNAKNHFKEAEIIMNAGQRGAVTIATNMAGRGTDIKLGPG------------------------------------- 498 
258507894 456 HTVLNAKNHFKEAEIIMNAGQRGAVTIATNMAGRGTDIKLGPG------------------------------------- 498 
301065946 456 HTVLNAKNHFKEAEIIMNAGQRGAVTIATNMAGRGTDIKLGPG------------------------------------- 498 
297623055 470 HEVLNAKHHAREAEIVAQAGRSGAVTISTNMAGRGTDIVLGGNpeaiagqlverygvsrydenvelcikavmlgkvdiar 549 
94985162  552 tlglripgmteqfirqaqqlqkdiiadrerVRELGGLHIIGTERHESRRIDNQLRGRAGRQGDPGSSRFYVSFEDDLMRL 631 
33519622  536 ----------------mlriksdwkerhdsVLKSGGLHVIGTERHESRRIDNQLRGRSGRQGDAGSSRFYLSMEDSLIRI 599 
116494436 499 ------------------------------VTELGGLAVIGTERHESRRIDNQLRGRSGRQGDPGSTQFYLSLEDDLMKR 548 
161579493 552 qlgmqipgitldfirqaqelhratvedrqrVRDLGGLHIVGTERHESRRIDNQLRGRAGRQGDPGSSRFYVSFEDDLMRL 631 
191637820 499 ------------------------------VTELGGLAVIGTERHESRRIDNQLRGRSGRQGDPGSTQFYLSLEDDLMKR 548 
226356705 552 mlgmqipgmtpefiqqaqqlqadtvadrarVQELGGLHIIGTERHESRRIDNQLRGRAGRQGDPGSSRFYVSFEDDLMRL 631 
258539139 499 ------------------------------VTELGGLAVIGTERHESRRIDNQLRGRSGRQGDPGSTQFYLSLEDDLMKR 548 
258507894 499 ------------------------------VTELGGLAVIGTERHESRRIDNQLRGRSGRQGDPGSTQFYLSLEDDLMKR 548 
301065946 499 ------------------------------VTELGGLAVIGTERHESRRIDNQLRGRSGRQGDPGSTQFYLSLEDDLMKR 548 
297623055 550 klvreieglpediiptlerlrdeakadrerVVELGGLHIIGTERHESRRIDNQLRGRSGRQGDPGSSRFYVSFEDDLMRL 629 
94985162  632 FASDRVVAMMDRLGM-DDTQPIEAKMVTGAIERAQARVEDRNFGIRKQLLEFDNVMSKQRDIIYAQRREVLLGtdEDVEE 710 
33519622  600 FASNKLVDLMKRMGM-KSGESIEHPWITKAIAHAQKKVESRNFDIRKQLLEYDDVANDQRRVIYEQRNKLLAM--LDVSE 676 
116494436 549 FGSDRIKAMLDRFKVaDDDQVIQSRMISRQVESAQKRVEGNNYDTRKNTLQYDDVMREQREVIYKQRQQVINEq-ETLKP 627 
161579493 632 FANDRVVGMMDRLGM-DDSQPIEAKMVTGAIEKAQARVEDRNFGIRKQLLEFDNVMSKQRDEIYAQRREVLLGpdEDIEE 710 
191637820 549 FGSDRIKAMLDRFKVaDDDQVIQSRMISRQVESAQKRVEGNNYDTRKNTLQYDDVMREQREVIYKQRQQVINEq-ETLKP 627 
226356705 632 FANDRVVAMMDRLGM-DDSQPIEAKMVTGAIEKAQARVEDRNFSTRKQLLEFDNVMSKQRDTIYAQRREVLLGpdEDVEE 710 
258539139 549 FGSERIKAMLDRFKVaDDDQVIQSRMISRQVESAQKRVEGNNYDTRKNTLQYDDVMREQREVIYKQRQQIINEd-ETLKP 627 
258507894 549 FGSERIKAMLDRFKVaDDDQVIQSRMISRQVESAQKRVEGNNYDTRKNTLQYDDVMREQREVIYKQRQQIINEd-ETLKP 627 
301065946 549 FGSDRIKAMLDRFKVaDDDQVIQSRMISRQVESAQKRVEGNNYDTRKNTLQYDDVMREQREVIYKQRQQVINEq-ETLKP 627 
297623055 630 FANERVLGMMDRLGM-DDTQPIEAKMVTSAIERAQKRVEDRNFGIRKQLLEFDNVMSKQREVIYKQRRDILLG--NDISE 706 
94985162  711 STEGMIADFTEMQLAFYAPIDqpAESWDL----ETLRTNMLEAVPQLEHYDFEALRHMAPEAAHAHLLEAVADAFDARKA 786 
33519622  677 VIHNIRYDVVDRILNIYIPLEiiENKKDLikleKCLKDDFNLVLSFSEQLDEDTSLYEGKEKIRVCILTEMIKQYKCVKE 756 
116494436 628 VLMAMINRTITRIVQTHTQGD--QKDWNL----DALYAWVTANMIDPEKFKRSQLDGKSQDELIGLLAEMAETNFQQKNK 701 
161579493 711 TTEGMIGDFVDSQLAAYAPIEvsHEQWDI----EQLRSAMVEAVPALETFDFESLRVNSPAEAQDRLLSAVADAFDARKE 786 
191637820 628 VLMAMINRTITRIVQTHTQGD--QKDWNL----DALYAWVTANMIDPEKFKRSQLDGKSQDELIGLLAEMAETNFQQKNK 701 
226356705 711 STEGMIADFVDMQLAIHAPADqsPDAWDI----EGLQAAIVDAVPQLEGFDFESLRHGSPAQAQDRLLSAVADAFDSRRE 786 
258539139 628 VLMAMINRTITRIVQTHTQGD--QKDWNL----DALYAWITANMADPEKFKRSELDGKSQDELIGLLADMAENNFQHKNK 701 
258507894 628 VLMAMINRTITRIVQTHTQGD--QKDWNL----DALYAWITANMADPEKFKRSELDGKSQDELIGLLADMAETNFQHKNK 701 
301065946 628 VLMAMINRTITRIVQTHTQGD--QKDWNL----DALYAWVTANMIDPEKFKRSQLDGKSQDELIGLLAEMAETNFQQKNK 701 
297623055 707 DVQDMIAEYVDAQVQNYLNKElePEEQDI----GALRTAIVEAVPALETFDFESLRGEDPDEATDRLVPALEAAYKAREA 782 
94985162  787 ELG-PTMLNSLARYVLLQVVDQHWKEHLHGMDVLRQGIGLRGYGQRDPFTEYKFEATNMFNDMIDNLKADVTKFIFRMQF 865 
33519622  757 MVG-INVMNAIEKGIILKTFDALWKEHLASMDYLRQGIHLRGYAQKDPKQEYKKESFSMFKKMLDHLQYEIISEISKLQK 835 
116494436 702 QLGdDAQMLEFEKVVILRVVDSAWTDHIDAMDQLRQSIGLRGYGQMNPLVEYQEEGYRMFEEMIASIDDDVTRLFMKAEI 781 
161579493 787 ELS-PTMMNSLARYVLLQVVDQHWKEHLHGMDVLRQGIGLRGYGQRDPFTEYKFEATNMFNEMIDALKADVTKFIFRMQF 865 
191637820 702 QLGdDAQMLEFEKVVILRVVDSAWTDHIDAMDQLRQSIGLRGYGQMNPLVEYQEEGYRMFEEMIASIDDDVTRLFMKAEI 781 
226356705 787 ELG-STMLNSLARYVLLQVVDQHWKEHLHGMDVLRQGIGLRGYGQRDPFTEYKFEATNMFNEMIDNLKSDVTKFIFRMQF 865 
258539139 702 QLGdDAQMLEFEKVVILRVVDSAWTDHIDAMDQLRQSIGLRGYGQMNPLVEYQEEGYRMFEEMIASIDDDVTRLFMKAEI 781 
258507894 702 QLGdDAQMLEFEKVVILRVVDSAWTDHIDAMDQLRQSIGLRGYGQMNPLVEYQEEGYRMFEEMIASIDDDVTRLFMKAEI 781 
301065946 702 QLGdDAQMLEFEKVVILRVVDSAWTDHIDAMDQLRQSIGLRGYGQMNPLVEYQEEGYRMFEEMIASIDDDVTRLFMKAEI 781 
297623055 783 ELG-APLMRELERYIVLQVVDNHWKEQLHAMDVLRQGIGLRGYGQRNPLQEYAFEAFNLFEEMKSGIRLQVAKLLFRVQV 861 
94985162  866 GQAS 869 
33519622  836 LNRS 839 
116494436 782 RQNI 785 
161579493 866 GGA- 868 
191637820 782 RQNI 785 
226356705 866 GQTG 869 
258539139 782 RQNI 785 
258507894 782 RQNI 785 
301065946 782 RQNI 785 
297623055 862 QTQA 865 
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