Conserved Protein Domain Family
COG3972

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COG3972: COG3972 
Superfamily I DNA and RNA helicases [Replication, recombination and repair]
Statistics
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PSSM-Id: 443172
Aligned: 62 rows
Threshold Bit Score: 244.741
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_052718165   1 MKNNFIITEKYKMPGEEAERRVWAKIVKDFSGNCCLAYWRYPMFLKVGEKRREPDILLLDQKLGVVIIEVKGLKIEQVAA 80 
WP_012031361  37 EAPNVFSGRTLPDFLIFHQRYGLLGIEIRDWKMKSVKKIDAESVYLGIKREAYRHPVQVARECLLPFILQMQKDAQLVQK 116
WP_013030316   1 ------------------------------------------MSTLIPSLGAARFDARGELRLAERLKDCLEDNAWVWHN 38 
WP_014402037  65 VKDWTSESIVQADRRQLALSTARGLIREPNPLLQAHAHAQEIKAILEADPALRQPTDSRDAGQLIMPWGYGVILPRIGRQ 144
WP_014707357  80 ETVELLTINGLKTVPNPFVQVRQYAYQGIRLLEADKELRQKGSKYDGNLVTPYAHGVVFTNITRNQIEAAIPAEYREKLL 159
WP_069973849  31 DYMVWVELNIKGNYPDFVVVGPDLGIMVLEVKDWDLNYIKKINKKEIELSDGTVKANPWDQSWRYCMSILNEVKRSDKFY 110
WP_086901151  76 NANEFVRETNGGRKSDPNPLIQARQCAFAAIDQLKRDPQLTQTKERYQGRLCFPYGYGAVLTNITRRQLNQLLDEEIQEN 155
WP_002641887  77 LNKNKCTLNVDEQIIQKVSPLIQARTYINNVVRELEKDAVLQQKEGEYAGNLVVPYAYGTIFTHFSRGQLRQKLQQENAE 156
WP_106890153  65 VKDWKIDSIESFDKHSVSLKTERGLTRAANPLAQARQYAERIARILESDPELRFPATHQHGNRLLIPWAYGVVFPNIRRE 144
WP_125972043  62 ALEVKDWKLSSLLRIDPQIVECNFNGQYKKDVNPLLKARDFINVTIDMLKKDPLLISPAASHYAGKLMMPYGHGLILANI 141
WP_052718165  81 IDGHRWSYVDFYEDFGNPYEQAENHLFSFLGLTDRKSTLRRRVAGRAVVALPNITRKQWQAKGFDQQLSNPPILFKddls 160
WP_012031361 117 AGQRAGDLVFSWGYGAVIGGWERCKVSPSKKVLLDRYFSEHDCLLDDELLTIDEPRFLQWLHGLSLYHYSQPLTEVqtqk 196
WP_013030316  39 IPVGPFGRHPDFVALHPQQGIVVLEVKDWRLDTIGNANSKQVELITDRGNVLTDNPFVQVRNYMFNVVNALQRDPLlvne 118
WP_014402037 145 QFVEGGLEAAMAGHRVICQDEMPETVEPEAFQQRLWAMFGHSFPVALSYPQIERIRWHLFPELRLTSAAGQFGLFGdett 224
WP_014707357 160 PDHLMIYKDEMTESVDPEEFQKRLWDMFPYQFQTKLTLPQIDRIRWHLFPEVRISQPSQENLFGTLINQPDTPEDLstls 239
WP_069973849 111 KDKLKDLIEFPCNHAIVFPNIYQAEFEQSITDTKVLESKYVLFGDEINNLLRTRSEKKLVEKLKKMMQRDFGGDFFitsd 190
WP_086901151 156 VLPASRVICKDEMLPTADPELFQQRLWDMFDYQFGEKLTLPQIDRIRWRLFPEVRIDAPAQDLFDDDDSEDNEKPAdti- 234
WP_002641887 157 ISDWDNIFPYELVMYQDDLAYGMPSQEVKNRLARMFINSFPCHLNREQIDRIRWHLFPEIRISTPVQQDLFAEKNEqpen 236
WP_106890153 145 QLAQHDLDAILPAHLLICQDEMLESTDPQRFQERLWAMFAQTFPCHLTLPQISRVRWHVFPEVRVGGEQFGLFETAnveh 224
WP_125972043 142 TRKDFNDARLADVLPEHLVICQDEMTESADAEAFQKRLWDMFLQPFPCCLTLPQIDRIRWHLFPDVRIECRQESLFdaps 221
WP_052718165 161 gdiqqqlktvtavadgdplddgkwqdlch------------------------------------------------vvg 192
WP_012031361 197 vraylfpeciand------------------------------------------------------------------- 209
WP_013030316 119 ggsfkgkpvfsfghgvafsnitrkqfeqtdlwevfppercifrdemaekvdadafrervwrmvsprigpalslpqidrvr 198
WP_014402037 225 aeag---------------------------------------------------------------------------- 228
WP_014707357 240 e------------------------------------------------------------------------------- 240
WP_069973849 191 kmreirrll----------------------------------------------------------------------- 199
WP_086901151     --------------------------------------------------------------------------------    
WP_002641887 237 hqndkttdi----------------------------------------------------------------------- 245
WP_106890153 225 aah----------------------------------------------------------------------------- 227
WP_125972043 222 aepaa--------------------------------------------------------------------------- 226
WP_052718165 193 atsvlrvqevpsvekivtksdainaakerVMAMDIEQEKAAKQIPEGPQRIRGIAGSGKTVLLCQKAAAMHLKHPDWDIA 272
WP_012031361 210 ------------vrfklpknldkmdlpdtVRVMDNTQEYIVRNLGDGHRVIHGVAGSGKTLLLEYFAKKRAAEEFQKPIL 277
WP_013030316 199 allfpeirvtqialpfddpaktspaddrlLAVMDMQQELLARSMGEGHRIVRGVAGSGKTLILAFRAEQIAR-AASRPVL 277
WP_014402037 229 ----------------------plqipelIRVMDQQQESLARSLGDGHRVIHGVAGSGKTMILGYRAMHLAR-SQNRPIL 285
WP_014707357 241 ------------------------qipdiIRIMDIQQEQLARSLGEGHRVIHGVAGSGKTLILGYRAELLAK-LTNKPIL 295
WP_069973849 200 ----------------ypeviiskkkdgtIRTMDAKQEELARGMNYGNVIIKGVAGSGKTVILTARAKYLANKHADWNIL 263
WP_086901151 235 --------------------------pdiVRVMDIQQEQLARSMGDGHRVIHGVAGSGKTLILGYRCLYLAQ-AVQKPIL 287
WP_002641887 246 -----------------psvkpitqipeiVKVMDMQQELIARMMGDGHRVIHGVAGSGKTLILGLRAQILAE-RTNKPIL 307
WP_106890153 228 ----------------------amaipdlVRVMDLQQEALARSLGSGHRVIHGVAGSGKTMILGFRAQQLAA-TPGKPIL 284
WP_125972043 227 ---------------------qtmiipdlIRVMDVQQEQLARSLGEGHRVIHGVAGSGKTMILGYRAQYLAK-SSNKPVL 284
WP_052718165 273 MVFFTRSLYDIVIDLIGRYishftqgeviydpDTSRLRVLHAWGAK--GQpglyseackqHHVTKLtpstvghqgspTEL 350
WP_012031361 278 VMCFNTMLSSILRKRLPKN---------------VDVFYFYEWCDKikRE----------YGIs------------gKDD 320
WP_013030316 278 LLSYANGISGRLENAMQDRgv----------eDKVVTSTFHSWCWKmlRT----------YGLPIAteke---ipdfSER 334
WP_014402037 286 VLCYNPALAARLLHVVRQRgl----------eDRISVFDFHRWCQEmlVT----------YHVPVPrr-------dgADD 338
WP_014707357 296 VLCFNITLAAKLRSFMVSKgi----------sDKVNVHHFHDWCSQqlKT----------YHVDVLag--------dEPY 347
WP_069973849 264 VLCYNVTLCKYLRTEVFNSe------------TNIKVMHFHGFFEEncIT----------LNIDYN-----------KNK 310
WP_086901151 288 VLCFNITLAARLRCFIAEKgi----------eDKVRVHHFHDWCSLqlKT----------YSVDLIpg--------kEPA 339
WP_002641887 308 ILCYNITLAAKLRVLMQERgl----------sECVKVHHFHGWCGHlvKQ----------FGIQYNaee------qqLEG 361
WP_106890153 285 VLCYNKTLASRLQQLLAERgi----------dERVQVLNFHAWCLSmlNA----------YGLAKPss-------qgEAF 337
WP_125972043 285 ILCFNKGLSQKLKSWIEEKnl----------aEKVVVKTFHSWCSEmtRT----------YLLPKSkak-----tnsSEY 339
WP_052718165 351 LVVAATKFLDQLdlQGRQLEGMFDAILIDEGQDLVVDehlkregrqsYYWMAYHLCKDIpvpqtsdmfdkgikpdnklpl 430
WP_012031361 321 EMSVADDVCRAIl-QRGVLNGAYSSILIDEGHDFKSE----------QLKALVKTVDPDt-------------------- 369
WP_013030316 335 QAANVQAVLDAAe-RGLIPGGQYDAVLIDEAHDFEPQ----------WLALAAKMVNPDt-------------------- 383
WP_014402037 339 RQAWPEAVIAAVe-RGQIPRAQYGAVLVDEGQDFEPD----------WYRLIVQMVDPAs-------------------- 387
WP_014707357 348 WERQVISVINGVs-KDDIPRAQYSAVMIDEGHDFESD----------WLKLVVQMIDPEt-------------------- 396
WP_069973849 311 IAEIISKLTNGQ----YSRLARYDAILVDEGQDFEKS----------WLEFLFKLLNGSt-------------------d 357
WP_086901151 340 YERQVKSVIKGVe-QSQIPRAQYSALMIDEGHDFEQD----------WLKLVVQMIDPEi-------------------- 388
WP_002641887 362 FEKPVYAVLRAVa-NGSIPKEQYGAILIDEGHDFEAD----------WLRLIVQMLDKSe-------------------- 410
WP_106890153 338 FKDLVEAVIKAVd-QRAIPRSQYRAVLIDEGHDFAPD----------WLRLVVQMLDPSt-------------------- 386
WP_125972043 340 WEETIQSVINGVn-RKEVPAGQYAALLIDEGHDFKPE----------WLRLVVQMVDPAs-------------------- 388
WP_052718165 431 RRLIWGYDEAQCIEAPVipsaaevfgaenstlmmGQYQGgIKRSIVMQRCYRTPGPILVAAHAIGMGLLRGEgmisgvtN 510
WP_012031361 370 NSLLLFYDDAQNIRDTQnlkf---------plksVGIKA-QGRTTILRINYRNTQEILSVAFNFYQQFIAVN-------D 432
WP_013030316 384 KALMIVYDDAQAIYKGRkrpv----------wkqLGIEA-AGRTTVLKVNYRNTAQILRFARKFAADVIGAPgvc----- 447
WP_014402037 388 KSLLVFYDDAQPGRDSParpaf--------swksVGIEA-AGHTTILKLNYRNTLEILAVARDFAQTLLQGA-------- 450
WP_014707357 397 NSLLLLCDDAQSIYKKKsglsf--------slasTGIQA-QGRSTILKLNYRNTREILAFAYDFAKEYFGAS-------- 459
WP_069973849 358 NHFLLTSDGAQNLYGREyfl--------------sdIGVqAEEIDILQNNYRNTEQILMFAYGFLTDETEVPidk----- 418
WP_086901151 389 NSLLMLYDDAQSIYQKSslkf---------plsaAGIQA-RGRTTILKLNYRNTREILTFAYDFAKDFIQAH-------D 451
WP_002641887 411 NHLLLLYDDAQSIYPHQagqkgi-----kfslssVGIEA-RGRTVKLANNYRNTKQIIGFAHIFAQQNLAER-------E 477
WP_106890153 387 NDLLMLYDDAQSIYQQkrqf----------tlasVGIQA-QGRTTILRLNYRNTIEVLAMAKSFAEQVFEGA-------E 448
WP_125972043 389 NALLMLYDSAQDIYQKSskrqf--------tfssVGIQA-RGRTTILKLNYRNSAEVLGVAYEFARDLLSAQ-------D 452
WP_052718165 511 QRDwnnlgyevegkfltgQQV---KLWRPAEnspnpmsELSAE-PSMEVAYFHSRTEEIRDTAARIVADiNIQGLKPSrQ 586
WP_012031361 433 TEDgedgalnreifadeeQKIp---LIRPVK-------SGRASgIVPILRLCQSADEECQYIAKTIDNW-LKAGVLRG-D 500
WP_013030316 448 ----------------agDESa---ILMPED-------GGREG-VEPAVRQCVSHDGEAHAIAEWLQGR-KAAGYQWG-Q 498
WP_014402037 451 AEP---------------GGDs---LVSTDS-------AGRHG-PLPELLRTADAADEARQLLQMIRRE-QAAGRPLS-A 502
WP_014707357 460 HDD---------------VDIp---LIQPEA-------AGIHG-ERPTVHFLKQWQDEISDTITCIKKW-HQRGGEWR-D 511
WP_069973849 419 ----------------slDKAnnnFITDPKR-------IYRKG-PVPNIKKCTNFNEEINAAIDKIKDL-NNQGIPYD-E 472
WP_086901151 452 ADE---------------DHVp---LIAPEV-------AGVNG-PPPAFRRFPTPADEASYMVRCIKAW-QGQGTELS-S 503
WP_002641887 478 SDE---------------DNIp---TVEPCA-------VGADG-YSPFIKMCQNWQDELAYLERCLKKW-QQENISLN-E 529
WP_106890153 449 DPT---------------RDTp---LLAPES-------AGRRG-PFPSLSRYDNTGDEIAGMLVAIREA-QASGLAAD-Q 500
WP_125972043 453 AED---------------DGVp---LVLPQT-------AGRRD-IAPEFIRLPNFNAEIEAIMLKFQQC-QEQGIAWH-D 504
WP_052718165 587 ILVVIlgnkkfdylDMNSDIEQLSTALRQAGINFYIPSAtkvnelkpkypNTDPNLFWYENAVTIAEVNRAKGNEAEMVY 666
WP_012031361 501 IAVLYf-------nKKSQLGDELKAVLEKEGISAQYLNNp----------KAKKEFVYQSDKITLSTVTASKGSEFSHVI 563
WP_013030316 499 MAVLY---------PRHFIGERFEKVLAKQGVPVDVAK------------DHHNRVETERDAVRFISMHNAKGLEFPCVA 557
WP_014402037 503 IAVLT---------RSTADSRDWQGRLEAAGISARVAHE-----------TGGSSLYLEGATVKLVTMQASKGLEFPVVL 562
WP_014707357 512 MAILF---------AANYQGKAIADSLHQHGIPYSWLGSk----------ETKHAYNPTKDSVSVLSIHSSKGLEFPAVV 572
WP_069973849 473 IAVVAak-----kdDVNNLYNEIKKTLKVTNV------------------RNEDTEVLKENSVKISTLHSIKGLDYAAVI 529
WP_086901151 504 IAIIY---------ANHAQGRRYHNALKAAGVPSSCLQSt----------ADKRAYDPQANQVVLLSRQSSKGLEFDTVI 564
WP_002641887 530 IAIIC---------ANKYQCKDVCNILNRLGLAHWALQEs----------SVRKQYNPRHDKIAVLAIPSSKGLEFSRVL 590
WP_106890153 501 IAVLY---------RYAYQSSRIAEALERAGIDHVQAQG-----------ADRQRLYERGGTVKLISMHSSKGLEFPLVL 560
WP_125972043 505 MAVLA---------YFNHQLDSIRDCFKKHQIPVQ------------------SGTLETAHGVSVLTLHASKGLEFPVVA 557
WP_052718165 667 VVGLDRIA-----SLEASISARNQLYVALTRAKGWVRLSGLQGFSLNDEVNT----VIA 716
WP_012031361 564 LAGLGDFKme-tlKLNKLESSVRQIYVGMTRAIHCLVLTSARENVFTKTLEEvlskSLS 621
WP_013030316 558 IGGLGELK-----KPEDIEDDVRLTYVAITRATHEAFITYSNMSELVSRLVV------- 604
WP_014402037 563 IPGLGTMPg----PGEDETEEARRLYIAMTRASERLIMLHDRDSIFSRRIRQainqVQE 617
WP_014707357 573 IVGISQL------KQDDINAEARLLYVGMTRAQKHLHMTVSQKNLLTERILKias---- 621
WP_069973849 530 ICGLNEFPgvdepITDWMKRMKKAIYVGLTRAKDEVYIYYSKENLFTIALERarkiVLE 588
WP_086901151 565 LGGIGELAd----DEDKLAQEARLLYVGMTRARRRLLVTGSGNNWFADRLREmssaqg- 618
WP_002641887 591 LMGTETLIa----HH---DDPTRLIYVAMTRAQSHLIMTLSGNNAVVEHIQNsfnaWKA 642
WP_106890153 561 IPGLCQMPn----ADQDEQEEARLLYVAMTRATERLMMSCVHESAFTQRVRNairdVER 615
WP_125972043 558 IAGLGSLPh----QKSEESEQARVLYVGMTRAMNQLYLTADRDSVFAQKARAacekIAA 612
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