Conserved Protein Domain Family
CTI

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pfam06934: CTI 
Fatty acid cis/trans isomerase (CTI)
This family consists of several fatty acid cis/trans isomerase proteins which appear to be found exclusively in bacteria of the orders Vibrionales and Pseudomonadales. Cis/trans isomerase (CTI) catalyzes the cis-trans isomerization of esterified unsaturated fatty acids in phospholipids, mainly palmitoleic acid (C16:1) and cis-vaccenic acid C(18:1), in response to toxic organic solvents, heat and osmotic stress, and heavy metals. The CTI protein is located in the periplasm and has been shown to be involved in solvent tolerance in Pseudomonas strains.
Statistics
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PSSM-Id: 429196
Aligned: 37 rows
Threshold Bit Score: 965.911
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
zhongguo:Q91_0916   83 ASPTRLSIDAQSAKEWREKGFFSVLEkrlqhGGENNNQSLFKNMIDLALQNPLtPNQPIPKNIQLGLKRENTCPAPGEFS 162
Q881Z6              87 VAPTRLFYDARNTDAWRGKGFYSVLE------AQGGQAALMARMLDLGRSAPLpANSKIPDEIALGLNRENVCPMPGEFN 160 Pseudomon...
Q9I2P9              78 QETTRLYLDAHGADAWRRKDFWSVLE------PQDGQAALMARMLELGHSQPLqPNAKIPEGLDISINRANQCPTPASID 151 Pseudomon...
jgi:Psefu_2283      76 QATTRLFIDAHGAPAWRRKDFHSVLE------QQGGQAALMARMLELGHATPLpANSKLPKDLDISIERANQCALPGEFA 149
WP_011913348        76 QAPTRLFLDAEGEQAWRRKGFHSVLD------AQGGQAALMARMLDLGRSQPLtPNAKLPAELNIGIDRANNCPLPDEFD 149 Pseudomon...
jgi:Pmen_2160       75 QATTRLYLDAQGEAAWRQRGFHSVLA------GENGQAALIKRMLELGRSQPLePNAKLPGNLDIAITRSNSCPLPGEFA 148
BAN49379            78 QDTTRLYFDAHGAAAWQRKGFHSVLD------ASGAQAALMARMLELGRSSPPqANAKLPADLDIDINRLNQCALPTEFD 151
zhongguo:B5T_01476  87 AAPSRLFIDASSSGEWRNRGFFSVLE-----GRQTMDEGLLYQMLVLGRHHRFePNSKLPEEIQLGLGRANVCPAPEDMA 161
Q0VNV0              95 ISPTRLFKDAQTTAQWRDKGFYSVID-----STSGLQDSLLYQMLALGKKHSFkPNQKLPDDIVLGLARQNECPAPDEFD 169 Alcanivor...
jgi:Nhal_2913       85 VEPTRLTIDANSTAGWRDKGFFSVID-----GTEGPETSLLYRMLLLGRSQSFePNSKLPEDIKLGLKRENVCPTSEEFN 159
zhongguo:Q91_0916  163 DYAKNNPHGGMPLAVAGLNESEAQTLSTWLSEGAKiVTKNIDISPEHQAMIVQWETWLNSNDKRTALVARYLYEHLFLGH 242
Q881Z6             161 AYAAAHTQQGMPLAVAGLTDAEYQTLQRWLAAGAPvEQQSITPSVSETAQINAWEALLNQPGARQALVGRWLFEHLFLAH 240 Pseudomon...
Q9I2P9             152 AFIRKNPGSGMPFAVAGLSDDEYATLQKWLAAGAPvDQQPLRPTAAEARQVASWERFLNQPGAKQSLVSRWLYEHLFLAH 231 Pseudomon...
jgi:Psefu_2283     150 DFAGKNPMVGMPFAVTGLTEQDYQRVQRWLQQGAPvDEQALQASPAEAKQVADWERFLNGDGDEQRLVSRWIYEHLFLAH 229
WP_011913348       150 GYARKSQHGGMPFAVTGLSDQEYATVQRWLEQGGAvEPRQLQPSAREATQIEQWERLLNTPGPRGSLVARWLYEHLFIAH 229 Pseudomon...
jgi:Pmen_2160      149 AYAQKNPHGGMPFAVTGLSDDEYATLQQWLAQGAPvAEQKLQPSVAELEQIARWEAFLNAPGARQDLVSRWLYEHLFLAH 228
BAN49379           152 DYARKHARAGMPFAVTGLSEAEYQTLQRWLAEGGKvQEQVVQPSAAEARQVAEWETLLNAPGARETLVGRWLFEHLFLAH 231
zhongguo:B5T_01476 162 DYAREHPLEGMPLGLPPLSEREFDLLTGWLAQGAPlEATPVKLTLAEQSRIRAWESWLNRENPRQRLVARWVYEHLFLAH 241
Q0VNV0             170 DYAESHPMEGMPLAVAGLTDSEFTTIRQWLEQGAPlEPKIITPTNEEQQLIADWEAFLNQRDLKHQLVARWLYEHLFLAH 249 Alcanivor...
jgi:Nhal_2913      160 DYAKHHPYEGMPLATTGLTDEELTTIRRWLQAGAPqEPPKINLSEAEQSAINQWEALLNKKDNRSRLVARWLYEHLFLAH 239
zhongguo:Q91_0916  243 LYFDQvnqsagnspnaGIQFYSLVRSYTPSGQKIMPVNTARPFDDVNQAFYYRLKAIEETIVHKTHIPYRFDQQRLKHFK 322
Q881Z6             241 IYF-Egg--------eTQHFFQWVRSRTPSGQPVDLIATRRPDDDPGSDFYYRLVPVQGVIVHKTHITFAMSPQKLDRVR 311 Pseudomon...
Q9I2P9             232 LYFPEqg--------aPGHFFQLVRSRTPSGQPIDPIPTRRPNDDPGNSFYYRLWPIQGVIVHKTHITYPLTAKKLERVQ 303 Pseudomon...
jgi:Psefu_2283     230 LYF-Egg--------eAGHFFQLVRSRTPSGQPVDIVATRRPNDDPGTDIYYRLMPIQGVIVHKTHITYPLSAAKLAHVR 300
WP_011913348       230 LYF-Egg--------ePGRFYQLVRSRTPSGEPVDAIATRRPNDDPGTRFSYRLRPISDVIVHKTHITYPLSATKLARVR 300 Pseudomon...
jgi:Pmen_2160      229 LHF-Agg--------ePGHFFQLVRSRTPSGQPIDPIATRRPNDDPGTEFHYRLWPIQGVIVHKTHITYPLSDAGLARVQ 299
BAN49379           232 LYF-Dgg--------eTGHFFQLVRSRTPSGQPIDPIASRRPNDDPGNTFYYRLWPIQGVIVHKTHITYPLGAAKLARVK 302
zhongguo:B5T_01476 242 LYFDDgrq------grPPHFFSLVRSYTPPGEPIEPVASRRPNGDPGAPFWYRLWPITETIVHKTHITYALTDAKRERME 315
Q0VNV0             250 LYLDKgqd------skPAHFFKLHRSSTPPGEPIKPVATDRPNGMPPENFWYRIAPVPGTLVHKTHITFGLAKDKLARTK 323 Alcanivor...
jgi:Nhal_2913      240 LYFEDhad--------kqHFFELVRSYTPPGEPIKIVATRRPNDAPKNPFWYRLRPLIGTIVHKSHITYPLSEKKLNRVN 311
zhongguo:Q91_0916  323 QLFMTPGWSVDKLPGYSYLERSNPFITYQAIPAKARYRFLLDNAEFFIRNFIRGPVCRGQIATNVIRDQFWVMFENPKHE 402
Q881Z6             312 HLFYGTDWTVNALPGYGPGHRANPFLTFEAIPAVARYQFMLDNAEYFVRTFIRGPVCRGQIATDVIRDQFWVLFQDPAHD 391 Pseudomon...
Q9I2P9             304 ELFFGTQWNTDKVPGYGVQSRANPFATFAAIPPRARYQFMLDNAEYFTRTFIRGPVCRGQIATDVIRDNFWVVFQDPEQD 383 Pseudomon...
jgi:Psefu_2283     301 ELFFGTDWQVATLPGYGVQHRSNPFLAFEAIPAQARYQFMLDNAEYFVRTFIRGPVCRGQIATDVIRDNFWVFFQDPQHD 380
WP_011913348       301 ALFFAGDWTVESLPGYGANHRANPFKTFQAIPAEARYQFMLDNAEYFVRTFIRGPVCRGQIATDVIRDNFWVFFQDPQHD 380 Pseudomon...
jgi:Pmen_2160      300 ALFFGEDWPLDAVPGYGAQRRANPFETFAAIPPRARYQFMLDNAEYFVRTFIRGPVCRGQIATDVIRDNFWALFQAPEHD 379
BAN49379           303 ELFYSGDWAVDQVPGYGAQRRANPFETFQAIPAQARYQFMLDNAEYFVRTFIRGPVCRGQIATDVIRDNFWALFQDPAHD 382
zhongguo:B5T_01476 316 TLFFDTPWKLEALPEYDADARANPFLTFQAIPARARYQIMLDDAEYFVRTFIRGPVCRGQIATDVIRDQFWTVFQDPAHD 395
Q0VNV0             324 EHFFSTDWSVETLPGYGYEQRANPFVTFSAIPARARYQFMLDEAEYFVRTFIRGPVCRGQVATDVIRDHFWAVFQAPEQD 403 Alcanivor...
jgi:Nhal_2913      312 KLFFSDSWRVEQLPDYSDEGAANPFATFAAIPPRARYQFMLDNAEYFVRTFIRGPVCRGQFATDVIRDHFWTFFQDPDHD 391
zhongguo:Q91_0916  403 VYTNNPDYQHAMNPYLGLPGEKTSLLDFGSQWMKYETKRNQYIGQRQLTYQKIFPQGATKEHIWNGEQVNDNAFLTVFRH 482
Q881Z6             392 HYITDAAYRGHAMPLLAMPGQNDDVGSVLSLWLSYRDRRNQYEDLRRDSYAKMPA--PGWSTLWTG---NDNALLTVFRH 466 Pseudomon...
Q9I2P9             384 LFVTDANFRAQSEPLLALPGQIDELKNLLGLWSAYRDKRNEYEDLRQDVYADAPP--PTWNTIWHG---NDNALLSIFRQ 458 Pseudomon...
jgi:Psefu_2283     381 LYITDPAYRGEATPLLAMPGQLDEIGDLLGLWRSYRDKRNEYEALRTEGYAAAPA--PEWSQIWQG---NDNALLSIFRQ 455
WP_011913348       381 LYVTDRRFREQATPLLAMPGQFDEMGDLLAFWKTYRVKRNQYEQLRTKAYANAPA---DWPQIWAG---NENALLSVFRQ 454 Pseudomon...
jgi:Pmen_2160      380 LYVTDAAYRSEATPLLAMPGQFDEIGDLPGLWRDYRNKRNAYENLRKEAYADAPP--ADWAHIWSG---NDNALLSIFRQ 454
BAN49379           383 LFIADAQYREQATPLLAMPGQFDEIGDLLGLWRTYRDKRNEYEALRMQAYADAPP--PSWAHIWTG---NDNALLSIFRQ 457
zhongguo:B5T_01476 396 LYVDDADYQRRATPLLGLPGQHDNLISLGPQWLKYKHKRNRYLRERQQAYARHAPNGPTWETLWDGDGDNSNALLTIFRH 475
Q0VNV0             404 LYITDNNYRAQVSDLLGLPGQDDDLLALGPQWLKYSEKRNDYLKARKQAYGTNKPKGPDWDSLWDGDGDNRNALLTIFRH 483 Alcanivor...
jgi:Nhal_2913      392 LYLTDDDYQAKITPLLTTPGQNGDLLSMGPQWLSYQDKRNNYLGFRQQAYLKTKPQGPSLKDIWNGDGHNSNAALTVFRH 471
zhongguo:Q91_0916  483 HDNASVTKGWKGELPLTTWLMDYPLLERTYYELVVSFNVFGSASHQTQTRLYFDLIRNSSEVNFLRLMPADYREPLYKKW 562
Q881Z6             467 FDSASVNKGLIGDVPHSMWLFDFPLLERTYYQLAVNFDVYGNVSHQAQTRLYFDLIRNGAEINFLRLMPADQRDGMLGDL 546 Pseudomon...
Q9I2P9             459 FDSASVRKGLLGEVPQTLWLMDYPLFERTYYGLVVNFDVFGNVSHQAQTRLYFDLIRNGAEQNFLRLMPVDARQPLLDDW 538 Pseudomon...
jgi:Psefu_2283     456 HDSASVRKGLVGEIPQTIWWMDYPLLERTYYQLVVNFDVFGNVSHQAQTRLYFDLIRNGAEQNFLRLMPADARASIFDDW 535
WP_011913348       455 HDSASVRKGLIGEIPQTLWWMDYPLLERTYYQLVVNFDVFGNVSHQGQTRLYFDLIRNGAELNFLRLLPPASRQAILDDW 534 Pseudomon...
jgi:Pmen_2160      455 HDSASVRKGLLGEIPQTLWWMDYPLFERTYYQLVVNFDVFGNVSHQAQTRLYFDLIRNGAEVNFLRLLPAGARKGYLDDW 534
BAN49379           458 FDSASVRKGLIGEVPQTIWWMDYPLLERTYYQLVVNFDVFGNVSHQAQTRLYFDLIRNGAEVNFLRLMPADSRAALLGDW 537
zhongguo:B5T_01476 476 HDSASVRRGLIGDLPLTTWVMDYPLFERTYYALVVNFDVFGSVSHQAQTRLYFDLIRNGAEQNMLRYLPAAARKPVLDDW 555
Q0VNV0             484 HDNSSVRKGLIGDLPLTTWVMDYPLFERSYYNLVVNFNVFGSVSHQAQTRLYFDLIRNGAEQNTLRYLPAKLRQLVLANW 563 Alcanivor...
jgi:Nhal_2913      472 FDNSSVKRGLLGAFPKTVWIMDYPLFERSYYELVVNFDVFGNVSHQLQTRLYFDLIRNGAEQNFLRWLPPQSREQYLNDW 551
zhongguo:Q91_0916  563 YPTFANIKTEFTYHDIDIDSPVAINYETKEPYSELLTSQLNDYPALSKAKDSINrcdaecheaaslkketFEHQGTQINQ 642
Q881Z6             547 YQDGGKFKMWLDYQSIDDDTPTGIKLDAKAPQRDFAFKLIERSGSLNAAPDPINrcagay-----csrasLDSTFAQAEQ 621 Pseudomon...
Q9I2P9             539 YQNSGKLKMWMDYQAFDDDTPSALGLPEKQPKKAFAEELLRRYGDLNARPDPINrcldgn-----cyrpgIDRELQDAEQ 613 Pseudomon...
jgi:Psefu_2283     536 YQYSGKLKAWMDYYPLDKKSPSGLALSGDDPKHQFAEQLLQRFDGLNARRDPINrcsneh-----cyrdgLPADLRQAEQ 610
WP_011913348       535 YEKSGQLKLLLAYTSVDRATPTQLALDSGDPKRAFARQLLARHAGINAAPDPINrcqgth-----cyrdhQPAELQRVEQ 609 Pseudomon...
jgi:Pmen_2160      535 YQNSGKLKMWLDYTSVDHRSPSGLTLEDQNPKQQFAVQLLQRYAGLNARPDPINrctgah-----chrdgLPPELRDAEQ 609
BAN49379           538 YQNSGKIKMWLDYQSIDKDTPTALRLPEQDPKRAFANELLTRYAGLNARPDPINrcsdgr-----cyrpnVAPELQNAEQ 612
zhongguo:B5T_01476 556 YQKTGKLKLFISYASVDTDTPTGIDYGTSTPKQEFDGKLLTRFAHLNARPDPLNrcqdeh-----calpgANGLEQRVQQ 630
Q0VNV0             564 YQNTGKLRLAISYESVDTDLPTSIQFDTSTPMNEFNNNLLIKFAKLNARPDPINrcdgen-----cqrpnVSAWKQDADH 638 Alcanivor...
jgi:Nhal_2913      552 YQDTGQLKLFLSYASIDKTSPTAVAFHSQYPKKEFLKQLLPYLGAIAGPKDVINrcskke-----crrtgSSLFAQRVDK 626
zhongguo:Q91_0916  643 LLSKLASTPASQLkaiNWLPEISFIKIEQLDGQFLSYSMLKNRRHSSVSFILGESLRHQDQQDTLAIFPELIGSYPNLMF 722
Q881Z6             622 ALSRLTSRPAAGLkviDQLPEASMLRIQGSDGKRLMYSMLRNRAHSNVAFLLGESYRYIPGLDTLTIYPGVLSSYPNFIF 701 Pseudomon...
Q9I2P9             614 AFSRLVSRPAAGLkviERFPEASMLRIRTSSGKREVYTVLRNRAHSNVAFMLGESLRYQPGLDTLTIYPGVLSSYPNFMF 693 Pseudomon...
jgi:Psefu_2283     611 ALSRLAAKPAAHLpviEQLPEATLLRVEGEGGRREVYSLLRNRAHSNVAFMLGEELRYQPRLDTLTVYPEVLSSYPNFMF 690
WP_011913348       610 ALSRLTNRMAAGMpaiLHLPEATLVRVEYAGGRREIYSLLRNRAHSNVAFMFGESLRWQPRLDTLTVYPGILSSYPNFIF 689 Pseudomon...
jgi:Pmen_2160      610 TLSRLASRPAGGLrviRQLPEATLLRVELADGSREVYSLLRNRAHSNVAFMLGEELRYQPRLDTLTIYPEVLSSYPNFLF 689
BAN49379           613 VLSRLVSRPAAGLrviDQLPEATLLRVELPDGRREVYSLLRNRAHSNVAFMLGEELRYQAGLDTLTLYPGVLSSYPNFIF 692
zhongguo:B5T_01476 631 ALSPLASRRADDLpviDHLPEVSLLRVRGEDGDLAVYTLLRNRAHSNVAFMMGESLRYQPELDTVTIYPGVLASYPNFMF 710
Q0VNV0             639 ILSSISSRRAANLqavNFMPEVSMIHVRGNKGEQEIYSLFRNRAHTNVAFMMGESLRYQPPLDTLTLYPGVLASYPNFMF 718 Alcanivor...
jgi:Nhal_2913      627 ALTILVGPTAKDLpviNFLPEMSLLCIYSEQGEREIYSLVRNRMHTNVAFIAGEKLRYLPERDTLTISPGILGSYPNFAF 706
zhongguo:Q91_0916  723 VISIKELNDFVFALSQADTPEAFDAVINKWGIRRMNPNFWNVLHDFTTSLNTKRPLESGIYDINRYG 789
Q881Z6             702 NIPAAQVPAFVDAMQQSKDQASFEQIVQRWGIRRTHPLFWTYFHDLNHYLQETEPREAAVLDMNRYE 768 Pseudomonas syringae p...
Q9I2P9             694 DLPATDAEAFVGALEAAKSGEDFDKVVERWGVRRSNPQFWSYFHDLEAYIRETEPVEAGALDMNRYE 760 Pseudomonas aeruginosa
jgi:Psefu_2283     691 SVPAAQVPDFVTAMEQARDAKAFEKIVERWGIRRTHPQFWQYFHDLTAHIREHEPVEAGVLDMNRYE 757
WP_011913348       690 NLPAADVPIFVAAMEQVKAVADLERLVERWGIRRSHPQFWHYFNDLTRYLEETEPVEAGVLDMNRYE 756 Pseudomonas stutzeri
jgi:Pmen_2160      690 SLKASEMDEFVAQMERAADAAAFERIVERWGIRRSHPQFWRYFHDLAEHIRETQPVEAGVLDMNRYQ 756
BAN49379           693 NLKSTEVEDFVSAMERAKDAAAFEQVATRWGIRRTHPQFWFYFHDLAAQIRETEPVEAGELDMNRYQ 759
zhongguo:B5T_01476 711 HLREGELEDFVRAMERAGDESGFERLVQRFGVRRTHPEFWRYFDDLGDYLLEHEPTQAGVLDLNRYQ 777
Q0VNV0             719 LVQEDQLQAFVTQMEAVKTEKDFTELVDAYGIRRTHPEFWQYFHALNQYLEKHEPTQAGILDMNRYE 785 Alcanivorax borkumensi...
jgi:Nhal_2913      707 NIAEKELGDFVSALNSSKDEESFTQIIERWGIRRTHEDFWSLVSDFTFYLEETLPLEAGILDLNRYQ 773
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