Conserved Protein Domain Family
PRK03584

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PRK03584: PRK03584 
acetoacetate--CoA ligase
Statistics
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PSSM-Id: 235134
Aligned: 153 rows
Threshold Bit Score: 881.054
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
121592489   1 METH----HNIPPTHPPYAPQIRRYQDWLQAQHGLRF----------DDYDALWRWSTTDLDAFWQSVWDYFDLQSPTPH 66 
226364028   1 MTAPgrevLWTPPPERVFASNMSRYQRWLAAEKNVAT----------TDFDSLWCWSISDLEKFWLSIWEYFDVIASAPP 70 
111017561   1 MTAPgrevLWTPPPERVSASNMSRYQRWLAAEKNVCT----------TDFDSLWCWSISDLEKFWLSIWEYFDVIASAPP 70 
11497813    2 EPKI----LWEPDSEFIKNSNLAEFVEWLSSNKGLDFvvsenarenvENYKNLWKWSVENLEDFWESVWEFFEIKSYSDY 77 
78062059    4 EGEL----LWTPGETSVRGSHLARYLDWLATDRDLAF----------ADYDALWRWSVREPDAFWASIWQWYGVQYDGSA 69 
184201508   9 ERAR----LWTPSEESIRGSRMHDFAQWVSRTRGVPT----------EGFEALHAWSVENLDAFWGAVWEYCGIVASSEA 74 
56475602    4 EGDL----LWTPSADWVTNANVTAFMNWLQDTRKLKF----------ANYGELWRWSVTELESFWGALWDYFSIEASAAP 69 
56478705    4 EGEL----LWTPSADWVRNANITTYQNWLRDQCGLVF----------DDYDALWRWSVADVEGFWRSMWEYFSLESSTPW 69 
154251608   4 MGDL----LWSPSEGMVADANVTAFIAWLNARGH-SF----------GGYEDLRRWSVADIAAFWEAVWQFFGVTSSTPY 68 
256391388   6 QPAAfgelLWTPTDAQRLGSPLQRYLDWLPKQGVGPF----------PAYADAWQWSVEHPAEFWESLWRYFDVQAATPY 75 
121592489  67 SAVLAKNVMPGAQWFPGAQVNYARQVLRhvdaaQAAG-QPALIGRNERGERRELSWPALRRQVAALALHMRAQGVQPGDR 145
226364028  71 HTVLADPQMPGARWFPGTRLNWAENLLR-----HTDQaGPAIISVDETGTTGELSRAELVAQVANLAAHFRNIGVRPGDR 145
111017561  71 QTVLSDPRMPGARWFPGTRLNWAENLLRh----TDRT-GPAIISVDETGTTGELSRAELVAQVANLAAHFRKIGVQPGDR 145
11497813   78 KTVLDERKMPGAKWFEGATLNYAEHAFL-----KAGE-GEAVVYVREDGLRRALTWSELERQTAAFAAWLKDMGVKKGDR 151
78062059   70 RRVTDGAPMPHTRWFPDARVNYAEHVLQna--aHAGA-APAFHYASETRPLQTMSLAELASQVRRVATRLRDLGVVPGDR 146
184201508  75 TAALEDRSMPGACWFPGARLNYAENTLRwa--eSRPD-EVAIVGEHEDGAPVSWTWRELESRVAALAQRLRELGVGRGDR 151
56475602   70 SCVLGSRKMPGAHWFPGAKLNYAQHVMRq----ERAG-SHAIMYLSENTPLTGMDWEDLAGQVRIVATQLRRLGVKPNDR 144
56478705   70 SRVLGDRAMPGAEWFPETRLNYAQHVLRq----ERPG-TDAVMFLSETTPLTGMAWEDLAGQVRILATRLRELGVQPGDR 144
154251608  69 ECVLRDEKMPGAEWFPGARVNYIRTLLSk----GSGN-KTAIHAAGEEGKARKISWDELKTQVFKVATALRELGIGPGDR 143
256391388  76 TAVLPDAAMPGARWFPGATLNFAEHVFRa----ASDD-RPALLFVEEGAEPVEISWAELRRQVAGLAATLRAWGVGVGDT 150
121592489 146 VAAYLPNIPETIVAFLACASIGAVWSLCAPDMGTHAVLDRFRQIAPTVLLAVDGVTYGRRDHDRCDVLAELRAQLPTLRH 225
226364028 146 IAAMLPNIAPTVVAVLAAASVGAVWSCCAPDFGVKGMVDRFAQIEPTVLIGVDGYQFNGKRVDRRDVFSALLDQLPTVRH 225
111017561 146 IAAMLPNIAPTVAAVLAAASVGAVWSCCAPDFGVKGLVDRFAQIEPTVLIGVDGYQFNGKRVDRRDVFATLLDQLPTVRH 225
11497813  152 VVAYCSQVPEAVIALLATASIGAIWAAVGGEVAPRAVIDRFKQLEPKVLIASDGHFYNGKEFNKLEDIKTVVSGIPSLER 231
78062059  147 VVAYLPNVPECAVAMLATTAIGAIWSSAAIDFGVRTVVDRFQQIAPKVLIAADGYHFGGKVFDRRREVAEIARALPSLQT 226
184201508 152 VAGVLPNIPETVVALLATASVGALWSVVNTDFGPSGVADRFAQIEPTVLFVVDGYRFGGSLRDMTGSYAGLLDVLPSVQQ 231
56475602  145 VVAYLPNIPQAIIAMLATTSIGAVWASCSPDFGSHGVLDRVAQLAPKVLFCVDGYRYGGKAFDRRGEVGEIIGALDSIEH 224
56478705  145 VVAYMPNIPETMIAMLATTSIGAVWASCSPDFGSRGVLDRITQLSPKVLFCVDGYRYGGKAFDRRTELRDIIGALPSLEH 224
154251608 144 VVSYMPNVPEAAVAFFATASIGAVWSSCSPDFGAASVIDRFSQIAPKLLFATDSYRYGGKNFDRRAEVRAMVDALPSLQH 223
256391388 151 VAAFLPNTPHAIVAQLAVASVGAVWSACGPDFGTQGVLDRFAQIQPKVFIGVDGYRYGGKRIDRRAECMETRDALPSVEH 230
121592489 226 VVLVNNL------NASKIVADTACYA-------SVIArnDAETAAFEPAWLPFDHPLWIVYSSGTTGLPKPIVHGHGGML 292
226364028 226 AIVVDNLgl---pFDGDRLHSVADYA-------DLVV----GDARPEYEQVPFDHPLWIVYSSGTTGMPKGIVHSHGGIL 291
111017561 226 AVVVDNLgl---pFIGEHRPSIAAYA-------DVVV----GDAAPQYEQVPFDHPLWILYSSGTTGLPKGIVHSHGGIV 291
11497813  232 VVLIPNLye---sHDLKLSIPLHYWE-------ETVD----RKEKLTFEPLPFDHPLWVLYTSGTTGIPKPIVHGHGGIT 297
78062059  227 LVWLPNVadampaDATSLPCAVHAWD-------ALLAgpDVPADTFRFERVGADHPLWIVFSSGTTGLPKAIVHGHAGIL 299
184201508 232 LIVVDQQps---gAVGALPEGALRLS-------EILE----CSAVPRYEQVPFEHPLWILYSSGTTGKPKGIVHSHGGVV 297
56475602  225 VIHLPYLep---hNPPPPDKRVRSWE-------TLLDhpPVPADGFQFEQLPFDHPLWILFSSGTTGLPKAIVHSHGGIL 294
56478705  225 IVHLPYLna---qDPAPPVDRALQWH-------ALMNhePVPAQEFEFAQLPFSHPLWILFSSGTTGLPKAIVHSHGGIL 294
154251608 224 VVHVAGAdp--dyGSEPLTAEAIAWG-------KLISrpAVSETRFVFEDTRFDHPLWIVYSSGTTGLPKPFVHGHGGVL 294
256391388 231 TVWVDYQf-----PEGPACAESIRWAeavagpeGATA----AEPQLVFEAVPFDHPLWILYSSGTTGLPKGIVHGHGGIL 301
121592489 293 LVMLQLAVLHNDIGCsyapnslGERFHWYSSTGWIMWNAQVGGLLGGTTCVLYDGNPGgnkeRPDWAVLWRMAAEERVTF 372
226364028 292 LEALKANALHYDLGP-------TDRVFIAASTAWVVWNMLVDVLAVGATLITYDGSPT----YGRPDHQFEICAHYGATR 360
111017561 292 LEALKANALHYDLGP-------TDRVFIAASTAWVVWNMLVDTMVTGAAIITYDGSPT----YGRPDHQFEICARYGATR 360
11497813  298 VEIFKG-SFHMDFKE-------GDRFLWYSPPSWMMWNTVVSGLLAGATIVFYDGSPL----YNFLQPLWQICEKEKLNI 365
78062059  300 AEHLKLMHLHVDLHP-------GDVMFFYSTTGWMMWNLLVASLLTGASAVLYDGSPM----HGGPECLWRLAADAGATC 368
184201508 298 LEFHKALGLHAGLGP-------EDIAYYAVATTWMVWNMLVGILLTGARIITYDGSPT----HGGPEKSFELVARHRATF 366
56475602  295 LEMHKLLAFHMDIHP-------GERTFFFTTTGWMMWNAVASSLLVGACPVLYDGNPA----YPTPDVLWKMAQDCGAAF 363
56478705  295 LEQNKLLRFHMDVHP-------GERTFFFTTTGWMMWNVVASSLLAGACPVLYDGNPA----YPEPDVLWKMAQDCGASF 363
154251608 295 LEALKFTHFHLNLKP-------DSCMFYFTTTGWVMWNILLSGLVAGSAVVLYDGNPM----TPKPDRLWELAAETGMTL 363
256391388 302 LEHYKAIAFHMGVEE-------GDRFFWYSSTSWMMWNIVLGSLLLGATAVLYDGSPA----FPDVSGLWQLAEKTGATM 370
121592489 373 FGAGAAFYGHCMKAGITPAACGDLSAIRVLGSTGSPLSAEVQQWGTDFfrqvsagaavvaapgrprqgatpsggsdphaa 452
226364028 361 FGTGAAYLTLCEKAGTQPGTDFDLTRLRSIMSTGSPLPDTTWRWIYDAv------------------------------- 409
111017561 361 FGTGAAYLTLCEKAGTEPGTAFDLSGLRSIMSTGSPLPDTTWRWIYDTv------------------------------- 409
11497813  366 FGTSAPFLHGCMKFGLQPGSQYDLSSLRMVGSTAAPLSPEGFEWVYRNv------------------------------- 414
78062059  369 FGGSPTFVQMMEKSGIEPGRQFDLSALRSVLLSGAPSTPETFAWFYRNv------------------------------- 417
184201508 367 FGAGAGILSMVQRAGVVPNVRMDLSSLRSILVTGSPLPDAAWDWVYEAv------------------------------- 415
56475602  364 FGASPTYVDIMNKTGIVPAARYDLSKLRAIMPAGSPVSPECTAWFYQNv------------------------------- 412
56478705  364 FGASPTYVDIMSKAGIVPGKKFDLTKLRAIMPAGSPVSPECTAWFYENv------------------------------- 412
154251608 364 FGASPTFLNGQMKLGIVPNKIYDLERMKSILLGGSPVMPEHMEWCFENl------------------------------- 412
256391388 371 LGTSAGYLMASQKAELHPGRDLDLSALRAIGSTGSPLPPTGFRWVYEAv------------------------------- 419
121592489 453 akrggdmstagppqsakaplggsdphavgergGDIWWCNISGGTDFAGAFIGGNRELPQTPGRMQCRMLGAAVEAWDERG 532
226364028 410 -------------------------------sNDVHLGSDSGGTDVATGFIGANPLSPVRTGELQGPYLGVDVQAWDENG 458
111017561 410 -------------------------------sPDVHLGSDSGGTDVATGFIGANPLSPVRVGELQGPYLGVDVQAWTETG 458
11497813  415 -------------------------------kEDVWLNSASGGTDVMTGFVGGCPILPVWSGELQCRWLGTKVEAYNIEG 463
78062059  418 -------------------------------kQDLWVTSQSGGTELCSGLVGAVPSLPVHAGEIQARMLGMAVDVWNDDG 466
184201508 416 -------------------------------sPTVRLGSDSGGTDVTSAFIGTNPYQSVYRGEIMGPYLGVAAESWNSRG 464
56475602  413 -------------------------------kEDLWIATGSGGTDCCTGFVGGVPTLPVYAGEIQAPSLGVAAAAFNEQG 461
56478705  413 -------------------------------kKDLWIATGSGGTDCCTGFVGGVPTLPVYAGEIQARSLGVAAYAFNDRG 461
154251608 413 -------------------------------hPDMWVTSQSGGTDVASAFVGGVPTLPVHAGEIQARCLGVDVHAFDDKG 461
256391388 420 -------------------------------gSDIWLNSLSGGTDVCTAFVAGNPLLPVYSGEIQCRALGCRVESWDPEG 468
121592489 533 RPVLDAVGELVCTQPIPSMPLFLWGDADGARYRASYFDMYPPghgrrpgggdlgpeagaVWRHGDWIEIGSSArpGCVIY 612
226364028 459 RSVIGEVGEMVIVAPMPSMPIYFWNDPDGSRYRDAYFETYPG-----------------VWRHGDWITIDANG--ACEVH 519
111017561 459 EAVVGEVGEMVITAPMPSMPIYFWNDPDGNRYRDAYFEVYPG-----------------VWRHGDWITMEADG--GCVVH 519
11497813  464 KPVINEVGELVIELPMPSMPLYFWNDKDFSWYKESYFSMFPN-----------------VWWHGDWLMITDRG--TAIIF 524
78062059  467 QPVVDEVGELVVTQPAPSMPIFFWNDDGGARYRESYFETFPG-----------------VWRHGDFMRITRDG--GCYIY 527
184201508 465 ERVWDEVGELVITAPMPSMPVFFWGDEDGSRYRAAYFDMFPG-----------------VWRQGDWVTQLSQG--PFVVH 525
56475602  462 EPVIDEVGELVITEPLPSMPVCFWNDPEQVRYREAYFEEFPG-----------------VWRHGDFFRINARG--GCFVL 522
56478705  462 ESVIDEVGDLVITEPLPSMPVGFWNDEGNARYREAYFEDFPG-----------------VWRHGDFFRINARG--GCFVL 522
154251608 462 ESVIGEVGELVVSKPMPSMPLFFWNDEGGHRYHDSYFDTYTD-----------------HWRHGDYFKVNERG--GCFIL 522
256391388 469 KPHLGEVGELVLTAPTPSMPVKFWNDPDGHKYHDAYFDVFPG-----------------VWRHGDWCTITERG--GVVIH 529
121592489 613 GRSDATINRHGLRMGTSEIYSAVEALPEVLDSLVVDLEYlGRASYMPLFVVLRSGLVLDDGLRARINDAIRASLSPRFLP 692
226364028 520 GRSDSTINRGGVRMGSADIYQAVEALPEIAEALVIGAELpNGGYHMPLFVVLRDGHDLDDALVEKIRTTIRRETSPRHVP 599
111017561 520 GRSDSTINRGGVRMGSADIYQAVEALPEIAEALVIGAELpHGGYHMPLFVVLRDGYDLDDALVEKIRTTIRREASPRHVP 599
11497813  525 GRSDSTIKRKGVRMGTLDFYKVVESMNEIISSLVVEVKGk-----IFLFVVPAHGIEVNEELKEKINRALKENLGAYFVA 599
78062059  528 GRADSTLNRYGVRIGSAEIYRVVEEIDEVADSLVVCCELpGGGFFMPLFVRLRNGETLDDTLRARIAERLRTLCSPRHVP 607
184201508 526 GRSDSTINRGGIRMGSADLTHVVDRVAGVSASMVIGAELaGGDYFMPLFVVPEPGTRLDEELRRRIVTAIREQVSPRYVP 605
56475602  523 GRSDATLNRQGVRIGTAEIYRALATLDEIEDALIVNLDLpHNQFFMPLFVKLSAGVELDPDLEKRITTLLRKEYTPRHVP 602
56478705  523 GRSDATLNRQGIRIGTAEIYRALATLEEVDDALIVNLDLpHGQFFMPLFVRLTNGLTLDKDIERRICDRLRKEYTPRHVP 602
154251608 523 GRSDSTLNRYGVRIGTAEIYRTIEGLEEIEDSIIVNLDLpGGNFFMPLFVVLKDGVALSDAVREKINKSLREKYSPRHVP 602
256391388 530 GRSDSTLNKQGVRMGSADIYEVVEKLPEIRESLVIGVELpDGGYWMPLFVHLAADAVLDDALKARVAAAIRAELTPRHVP 609
121592489 693 DEIVQVAEVPRTLSGKKQELPVKKLLLGQSMDkvvNPDAMANPGCLAWYVDFARHRA 749
226364028 600 DAIFDVPAVPTTRTGKRLEIPVKKLIQGVAPEtaiNRATVADTAALDWYIDYAERFR 656
111017561 600 DEIIDVPAIPITRTGKRLEIPVKKLIQGVSPEtaiNRATVADTDALDWYIDYAQRFQ 656
11497813  600 DYIIPVPDIPMTLNYKKLEVPIKKILLGWEVEkavNLDSIMNPDAVFKVVEAAKPYV 656
78062059  608 DTMVAMEQIPYTLTGKKMEVPVRKILMGRPVEqaaSRDAMANPAALDAYVAFAAEVP 664
184201508 606 DEIIEAPAVPRTRTGKPLEIPVKRLFQGADPTs-vNRATAEDAEVLDWYARAAQEFT 661
56475602  603 DRIIAVPGIPATLTGKKMEVPVRKILMGLPVEkavNRNTMANPQALDFFIHYAKSQQ 659
56478705  603 DKIIQVPEIPATLTGKKMEVPVRKILMGVPADkaaNLNAMANPRSIHHFVDYANSQH 659
154251608 603 DRIYEIDAVPYTLTGKKMEVPVRKILLGVPVDkaaSRDAMANPSAIDYFRDFAATQT 659
256391388 610 DELVEIPGVPHTRTGKRLEIPVKRLLTGADPAkavNLGTVDDPALIEWFMEYARQRD 666
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