Conserved Protein Domain Family
TFP_LU_ECD_Ly6G6d
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cd23547: TFP_LU_ECD_Ly6G6d 
extracellular domain (ECD) found in lymphocyte antigen 6 complex locus protein G6d (Ly6G6d) and similar proteins
Ly6G6d (also called protein Ly6-D, or megakaryocyte-enhanced gene transcript 1 protein) is a glycosylated, GPI-anchored, cell surface molecule, located on filopodia, which could act as cell receptor with potential roles in signaling or cell-cell interactions. Ly6G6d contains an extracellular domain (ECD) which belongs to Ly-6 antigen/uPA receptor-like (LU) superfamily and exhibits a snake toxin-like fold (also known as three-finger toxin/3FTx fold or three-fingered protein/TFP domain fold).
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Statistics
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PSSM-Id: 467077
Aligned: 4 rows
Threshold Bit Score: 145.446
Created: 28-Nov-2018
Updated: 27-Apr-2023
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
O95868        19 GNRMRCYNCGGsp-sSSCKEavTTCGEGRPQPGLEqiklp--------gnppvTLIHQHPACVAAHHCNQvETESVGDVT 89  human
Q6MG58        19 GQRMRCYDCGGgp-sNSCKQtvITCGEGERCGFLDrkpqpsse---qakqpsaTLSHHYPACVATHHCNQvAIESVGDVT 94  Norway rat
XP_007483615  19 GNRMRCYDCSPd---GPCSEtiRMCWEGERCGFLEqrlhqekeqikfpgnptvTLVHHRPTCVAVHRCEQeQIELVGGVP 95  gray short-tail...
XP_023422499 313 GIRMRCYDCGGagpsGGCAHsvITCGEGERCGFLErapqagl----aqsklnlTLRLHQPACVAIHRCNQvETESVGDVT 388 domestic guinea...

O95868        90 YPAHRDCYLGDLCNSA 105 human
Q6MG58        95 FTTQKNCCFGDLCNGA 110 Norway rat
XP_007483615  96 YTSHSSCCLGDLCNGA 111 gray short-tailed opossum
XP_023422499 389 YTTHRDCCVGDLCNSA 404 domestic guinea pig
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