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Antitoxin Phd_YefM, type II toxin-antitoxin system Members of this family act as antitoxins in type II toxin-antitoxin systems. When bound to their toxin partners, they can bind DNA via the N-terminus and repress the expression of operons containing genes encoding the toxin and the antitoxin. This domain complexes with Txe toxins containing pfam06769, Fic/DOC toxins containing pfam02661 and YafO toxins containing pfam13957. |
Jiyao W et al.(2023). "The conserved domain database in 2023.",