Conserved Protein Domain Family
YdeM

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cd03454: YdeM 
YdeM is a Bacillus subtilis protein that belongs to a family of prokaryotic proteins of unkown function. YdeM has sequence similarity to the hot-dog fold of (R)-specific enoyl-CoA hydratase. Other enzymes with this fold include the peroxisomal Hydratase-Dehydrogenase-Epimerase (HDE) protein, and the fatty acid synthase beta subunit.
Statistics
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PSSM-Id: 239538
Aligned: 47 rows
Threshold Bit Score: 171.212
Created: 7-Mar-2002
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
putative activeputative
Feature 1:putative active site [active site]
Evidence:
  • Comment:based on the active sites of (R)-hydratase and the peroxisomal Hydratase-Dehydrogenase-Epimerase (HDE) protein

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                                #   # #  #              #  ##                          
NP_388406     3 LDEFTIGQVFKTKSLKVSKDDIMRFAGEFDPQYMHVDEEKASKgRFNGIIASGIQTLAISFKLWIEEGFygddiiAGTEM 82  Bacillus subtili...
NP_692187     3 FTELSLGQVFTTKSIKVTKENITRFASEFDPQYMHLDEKKAEEgMFNGIIASGMHTLALSFKLWVEEEIygedviAGTQM 82  Oceanobacillus i...
NP_520164    12 FDDFQVGQTMEMGTYAVTEDEILAFARQYDPQPFHVDPEAARRsIYGGLISSGWMTCAVMMRLMVQNFLsksssmGSPGV 91  Ralstonia solana...
AAZ45947      6 LDDLTPGQRFTSPGLTLSEAEIIDFAWRYDPQPFHLDANAAANsPYGGLIASGFQSLAICFRLFIQSGVlaessmGSPGI 85  Dechloromonas ar...
ZP_01000963   3 FDDMYEGFTFETPGHVFTEEEIIDYARVYDPQPFHLDREAAAAsIYGGLIASGLQTCAISFALTLRANIinessmGSPGM 82  Oceanicola batse...
AAY60806      3 YDDFIVGETFKTKSLHITEEEIIQFATTFDPQYMHIDKEKAEQsRFKGIIASGMHTLSISFKLWVEEGKygeevvAGTQM 82  Staphylococcus a...
AAV94119      5 WEDFPAGFRYESDPWEMTGEEIMDFARKWDPQPFHIDPEAAKDgPFGGIIASGWHTLVTAFERWYASGLwaeasmGSPGM 84  Silicibacter pom...
ZP_01011281   6 FEDLPIGFTYRSGEAELTREAIVKFAREWDPQPFHVDDAAAAEsHFGTLIASGWHTLLIAFNLAMQSGVwdeasmGASGM 85  Rhodobacterales ...
YP_345128    20 AEDLGIGQRFDLGSHTVTEAELVDFATHWDPQWFHIDRAAAQDgQFGGLIASGIHTLAILQRLTFDAVGhswaaiAGRGI 99  Rhodococcus eryt...
ZP_01000109   4 LKDFSPGQVYRFRTAPLSADSIKAFATEWDPQRLHIDEDHATS-IHGSLIASGFQTMLEVFRPVMAEMMvdvaniGGLGF 82  Oceanicola batse...
Feature 1                                                                   
NP_388406    83 NHMTFIKPVYPDDELFTIVEVLDKQp--kRNELGILTVLLSTYNQKEVKVFEGELSVLIK 140 Bacillus subtilis subsp. subtilis st...
NP_692187    83 NNVKFIKPVFPDDLLFVIVKVIDIKk--lKKDQGILTVLLETFNDRDEKVLNVELSAIMK 140 Oceanobacillus iheyensis HTE831
NP_520164    92 DEIRWLRPVYPGDTLSVSSTCLEVRpsqsKPDRGVAINRWEARNQHGELVCTLVGMGLFG 151 Ralstonia solanacearum GMI1000
AAZ45947     86 DELRWLAPVRPGDTLHSEIEVLEVRpsssKPDRGIARLKYQAVNQRGEAVLSFIVIHLLR 145 Dechloromonas aromatica RCB
ZP_01000963  83 DRIRWLKPVRPGDEIRVTGTVRSATpsasRPDRGRVETDYVVRNQRDEPVLTYSITHLQR 142 Oceanicola batsensis HTCC2597
AAY60806     83 NNVKFIKPVYPGNTLYVIAEITNKKs--iKKENGLVTVSLSTYNENEEIVFKGEVTALIN 140 Staphylococcus aureus
AAV94119     85 TDVKWMVPVRPGDRLRVVATVIDSTasrsRPDRGRITVLSEIYNQDGQKVAEYSGINILR 144 Silicibacter pomeroyi DSS-3
ZP_01011281  86 DEVRWFLPAVPGDVIHVRAEVVTAErsksRPDRGRVSFRNDVHRADGKRIASYIGNHLMK 145 Rhodobacterales bacterium HTCC2654
YP_345128   100 RDLRFRRPVRPGDVLTGTVVIDDIQf--dDRARALVTTESTVVDSEGRVVLTVLLDAYLH 157 Rhodococcus erythropolis PR4
ZP_01000109  83 DNLRWLRPVRPDEPLDVEMTVNSVTpsksKPDRGVLHYTLSAKNPIGEVVFSTDTPVMIQ 142 Oceanicola batsensis HTCC2597

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