Conserved Protein Domain Family
NPH3

?
pfam03000: NPH3 
NPH3 family
Phototropism of Arabidopsis thaliana seedlings in response to a blue light source is initiated by nonphototropic hypocotyl 1 (NPH1), a light-activated serine-threonine protein kinase. Mutations in NPH3 disrupt early signaling occurring downstream of the NPH1 photoreceptor. The NPH3 gene encodes a NPH1-interacting protein. NPH3 is a member of a large protein family, apparently specific to higher plants, and may function as an adapter or scaffold protein to bring together the enzymatic components of a NPH1-activated phosphorelay.
Statistics
?
PSSM-Id: 460777
Aligned: 185 rows
Threshold Bit Score: 179.994
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
Q9FMF5       250 DWWFEDVSILRIDHFVRVITAIKVKGMRFELLGAVIMHYAGKW-LPglikeggvaiapamssaiggglglggdemsiscg 328 thale cress
XP_002460930 233 DLWIKDLVALPFDFFERIVQALRRQGMKEKYVSPVVLFYANKWvLS---------------------------------- 278
XP_003562811 239 DLWIKDLVALPLEFFRRIVQALRRQGMKEKYVSPVVLFYANKWvLS---------------------------------- 284
KRH14099     217 DLWMRDLIALPFGFFKRVIGSLRKQGMKEKYVSPIIVFYANKWvLS---------------------------------- 262
XP_006363043 217 DLWIKDLIALPFPFFKRIISSLRRQGMKEKYVSPIVLFYANKWvLS---------------------------------- 262
XP_002270802 216 DLWIKDLIALPFQFFKRIIGSLRRQGMKEKYVSPIIVFYASKWvLS---------------------------------- 261
EEF28516     216 DLWIKDLIALPFGFFRRIIGSLRRQGMKEKYVSPVIVFYANKWvLS---------------------------------- 261
XP_002321176 218 ELWIKDLIALPFGFFKRIIGSLRRQGMKEKYVSPIVVFYANKWvLS---------------------------------- 263
EFJ13915     306 EWWMQQLVELPYALFARIVAATRRQGMAERVIGQLMIKCVERWiF----------------------------------- 350
EFJ28028     153 KLWIKDLMRMPFRIFSRIIVSCTKQGLSPKNTSQLVVKYAEKWlFS---------------------------------- 198
Q9FMF5       329 snssggssgpdwkgglhmvlsagktnghqdsvaclagLGI---------------------SPKD---QRMIVESLISII 384 thale cress
XP_002460930 279 -------------------------------------KKThkfwatt-------ddeavdgETDAnrrAAAILEGVIGLL 314
XP_003562811 285 -------------------------------------KKThkfwacsgae--ddeagagrgESDAnrrAAEILQGVVELL 325
KRH14099     263 -------------------------------------KKTrqfwes---------scdkigEGGMnskASVILQGVVDLL 296
XP_006363043 263 -------------------------------------RKThqywqdarkdgkadndvedddDDDTnekVSKILQGILDLL 305
XP_002270802 262 -------------------------------------KKTrqfwensg-----gknkdkdkDNDInnkVSIILQGVLDLL 299
EEF28516     262 -------------------------------------NKTrqfwen---------sgdrlgNVDAnnrVSTILQGILDLL 295
XP_002321176 264 -------------------------------------KKTiqywes---------sgertsDANAndkVSTILQGVLDLL 297
EFJ13915     351 -------------------------------------GRGdadqqhknrdyylwcgsqrleKLEQrsdKCRLLESMVRLL 393
EFJ28028     199 -------------------------------------ESCcsdfd-----------endeqRSLTdelLQEMLDCIAHLL 230
Q9FMF5       385 P-----PQkDS-VTCSFLLRLLRAANMLKVAPALITELEKRVGMQFEQATLQDLLI--PGYnnKGE------TM-Y-DVD 448 thale cress
XP_002460930 315 PaesaaVAaGGaIPVAFYFALLSRSLTLELSDESRTKLREQVASNLQFARVDDLPL--PEE--EEadr--siADsR-EVR 387
XP_003562811 326 PvpaeaAI----LPAAFYFALLSRSLSLELKEASRARLRDLVASHLRFACVDDLPL--PEQ--EDadr--svADsP-EVM 394
KRH14099     297 PvgdkaRKv---IPVGFYFALLSRSLELGLTTESKAKLQDQITSLLHFSQVENFLL--P------EsgaklmSSsM-ELV 364
XP_006363043 306 PmgekaSKv---IPVGFYFSLLSRSLQLGLTSESREKLQDQIASLLYLARMEDFLL--P------DssndsiSScI-ELS 373
XP_002270802 300 PmgekaSRv---IPVGFYFALLSRSLEVGLRSDNKVKLQDQIVPLLHLAQVEDLLL--P------RcgtdsiSSsI-ELA 367
EEF28516     296 PtrekaRRv---IPVGFYFALLSRSFEVGLRSESKTKLQDQIASLLHLAQVEDFLI--P------KtgtdsvATsM-ELA 363
XP_002321176 298 PmrekaSRv---IPVGFYFALLSRSIGIGLRNDSKVKLQDQIASLLHFAQVEDLLI--P------SsrvdsdCSsM-ELA 365
EFJ13915     394 PvekqqL-----LPVSFLFRLLRHALGVGASTECRLQIETRIACQLELASVDDLLLglP------LkdgrtsKA---QLE 459
EFJ28028     231 Pfer------gaVPISFLFALLRYSVAIDAPRDCRVQIESRIACQLDLATIEDLLM--P------FksarqaPTlLcELD 296
Q9FMF5       449 LvqrllehflvqeqtegsspsrmspspsqsmyadiprgnnnnggggggnnqnakmRVARLVDSYLTEVAR-DRNLPLTKF 527 thale cress
XP_002460930 388 Amesivsnha------------------------------------asvqrrgveAVSELWDRYLVQFAG-DPKLRPERL 430
XP_003562811 395 Emesivsnhv------------------------------------amlqrqgaeAVAELWDRYLVQVVAcDPKLRLERL 438
KRH14099     365 Tmesiisayvass------------------------------srvnqtpeasnyRVAELWDAYLFNIAA-DPDMGPKRF 413
XP_006363043 374 Vmksivskyvsfn------------------------------melthtpsprnyIVAELWDVYLTKIAT-DPQWSSKRF 422
XP_002270802 368 Tmerifsnyvsan------------------------------mdakhtpsvnncIVAELWDVYLSLVAP-DPNMGPKRF 416
EEF28516     364 Tmesifstyvtln------------------------------mdanntpsprnsAVAELWDSYLSLIAS-DPKMEPKRF 412
XP_002321176 366 Tmesifstnvsln------------------------------mdtnnapsasnsTVAELWDTFLSHIAS-DPKMRPKRF 414
EFJ13915     460 Sarqiaslflqqqqqqqqddrkqgg------ggshvfsssrdetllfftnieavnTVSKIWDGYLEYLGY-DPGINPVTL 532
EFJ28028     297 Smkhvvalfmaqcra--------------------------vdsstglanwepiaNVARVWDEYLTEIGY-SGSITPTKF 349
Q9FMF5       528 QVLAEALPESARTCDDGLYRAIDSYLKAHPTLSEHERKRLCRVMDCQKLSMDAC 581 thale cress
XP_002460930 431 AELIGVIPAGDRKTHNHLYEAINTYLVEHQGLSGEEKATLCGHLDCRKLSHEAC 484
XP_003562811 439 EELIGVVPAADRKTHDHLYEAINTYLTDHPGLCGEEKAALCGHLECRKLSHEAC 492
KRH14099     414 MELIERVPPSYRQNHYPLYKTINSFLKTHSGISQDDKGAVCKYLDCQRLSQEAC 467
XP_006363043 423 LELIETVPLSSRQTHDHLYRALSTFLMAHPDMSQEEKGLVCKYLNCQKLSQEVC 476
XP_002270802 417 MYLIEIVLVSSRQTHDHLYRAMNAFLHAHPNISQEEKGMVCKYLDCQKLSQEVC 470
EEF28516     413 TGLVETVPISCRQSHDQLYQAMSTFLQAHLDVSQEEKGLVCKYLNCQKLSQEAC 466
XP_002321176 415 MELIETVPISCRQSHDQLYRAMNTFLQTHLDISQEEKGAVCKYLNCQKLSQWAC 468
EFJ13915     533 SDLIDVFPACARTSHDQLYKAIHVYLKSHPHVTHSERLLVCRSLNCQKLSQEAC 586
EFJ28028     350 AELIDAVPGFVRVSHDQLYKAIHVFLKAHPTASQSERSAICRPLDCQKLSQEVC 403
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap