Conserved Protein Domain Family
COG2461

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COG2461: COG2461 
Uncharacterized conserved protein AF0170, contains SAB, hemerythrin HHE, and PAS domains [General function prediction only]
Statistics
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PSSM-Id: 441993
Aligned: 90 rows
Threshold Bit Score: 368.433
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_019323639   1 Mm-----ADERIEVLKDILLELHHGASAESVQERFNQHFKGVSAIEISMMEHELMnaDTGITFEDVMGLCNVHANLFKGA 75 
WP_011684675   1 MselidnRAQRVRTLKGIIKRLHAGDAPDEVRNSLKELVCQTDYSEVMAMEQELI--ADGMPVEEIQGMCDLHSQVTREV 78 
YP_011802    107 aegntadrATRLATLRALLERLHQGTPLADLKEAFASAVGGISAAEVASLEKELV--AGGVAETEIKRLCSLHVDIFREA 184
WP_013558904   1 MselinnRQQRIEIMKSLIRQLHHGSSEEQVKHQLETMLAEADYSDVFLMEMQLI--QEGIPAESIQQLCDTHTHVLKKF 78 
WP_014225769   1 MsefinnSSQRKEMLRHLLLRLHEGDNPDVLRNRLVEVLSSIPYNEVVEVEQELIe-SGALSEDEILAFCDLHTAVLDGS 79 
WP_045090168   1 MsefinnSTMRKEKLRSLLLELHNGGNPALLRRHLINALRNIPYNEVVEVEQELIt-SNSLTEKEILEFCDLHTAVLDGS 79 
WP_006930310   1 MselinnRQERIEVMKNLIRQLHEGRDEEKVRRQLESVLQEADYSDVFLMEIQLM--EEGISRESITKLCDVHTKVLKKH 78 
WP_128425716   1 --------MDKINRLMTYIKRLNSREDGRSLYLEYKEDIDTVTPQEAFEIFHGLL--QDGLKEYEILLFLDKIINVFFES 70 
WP_076931146   1 MsefinnSTQRKEMLRHLLLRLHEGDNPEILRQRLIEVLKSIPYHEVVEVEQELIn-SNALTEQEILEFCDLHTAVLDGS 79 
WP_071136531   1 MselinnSSQRKELLRHLLLRLHEGENPEVLRQRLIEVLRNIPYNEVVEVEQELIs-SNALTEEELLDFCDLHTAVLDGS 79 
WP_019323639  76 IADVdVPDAEQEGHPVKVFKDENLALRAAIMRIRRIIENY-TKPENEDFRQE------ILKGLKHQFDLLGQFHHHYTRK 148
WP_011684675  79 LVQL-APAPVPPGHPVDTFRRENKALRESAARLQKAMNGVlETADDGDASAR-------LLEWRQALNELQDVDKHYQRK 150
YP_011802    185 LAPQ-HVPDMPPGHPVHTYRAENAEATRIADEIISQIDRMrSVPGDTESPLDelawsfSRRHVADLLADLAHVERHYTRK 263
WP_013558904  79 LDLQ-ETPETIPGHPVHTFIQENRELTRTTARVRLLIRML-DKMRDEDDASS------LMMQIHQALNDLMDVDKHYKRK 150
WP_014225769  80 IDQR-GAKPIPAGHPVDTFKRENRAIREQLDRYEVLKNEA-AQLTDAQAADQ-------VLKLRAVFNSLADIDKHYKRK 150
WP_045090168  80 IDLD-GAKDVLPGHPVDTFIKENSAIRKQIEAYRVVSKEI-DNITDSEVPGY-------VLQLRSIFNNFSDIDKHYKRK 150
WP_006930310  79 LDLT-ETPDAVPGHPLHTFLQENQALLQRTAHIRKKIAEL-EKVSEEESADV-------LMKIRFLLNELMDVDKHYRRK 149
WP_128425716  71 LSNY-RYQRPKNDNFLMDLMLENEEMKKKIEGIKIVIREPvp--------------siRRQKLLPLVEELKEFYPHYTKK 135
WP_076931146  80 IDQQ-GAKQIPAGHPVDTFKKENIAIRQQLEAYEEIKKKI-ADITDAQVTGY-------VLQLRTIFNNFSDIDKHYKRK 150
WP_071136531  80 IDLG-GARPVPAGHPVDTFKKENRALKDELLKIAALFNDV-NNINDRQLPGY-------ILQLRTLFNHLSDVDKHYKRK 150
WP_019323639 149 EKLFFPIMERY-GHDSPPKVMWGVDDDIRDLFKDAKATLAklPDGSIEE----LSQKFEAFAKEFEEMIFKEEAILLMIL 223
WP_011684675 151 EHLLSTCLERH-GITGPSKVMWGKDDQIRELLKDTSVALRq-SDTSVAElkvlAATTGAAAAGAVHEMIYKEEQILLPIC 228
YP_011802    264 EMQLFPMLEEN-GIEAPPKVMWEVHDDIRSLLRKARETVEgps-------pvaAATVARDAALAVKDMVDKEETVLFPMA 335
WP_013558904 151 EYLLFPIFERN-NLPGPPTVMWGKHDEVRQALRTTLEGLHevSQIIASEarafCTFAVEPLLQAIDEMIYKEEKILFPTA 229
WP_014225769 151 EYLIFPYLEKH-QITGPPKVMWGKHDEIRELLKGSFEALAt-PFRSAEElnsiVQLVLDPAIEMISGMIMKEEEILLPMT 228
WP_045090168 151 EYLLFPFLEKH-LITGPPKVMWGKHDETRELLNKSHEVLTs-PITNLKDlrliLINSLDITVEMIEGMIKKEEEILFPMS 228
WP_006930310 150 ENLLFPFFEKN-NLHGPSTVMWTKHDETRSYLKSVIQALNeaENISQKEmiafARLAIEPAIESVEEMIYKEEKILFPTA 228
WP_128425716 136 ENILFPYLEKKmEKFQGLTIMWALHDEVKREIEYAIELIKd-PESEDHA----VNVAIAQMFFGVLGLVRKEELILFPSA 210
WP_076931146 151 EYQLFPFLEKH-LITGPPKVMWGKHDETRELLKNSHEALAs-PISSTEElrsiIQLVLDHTVEMIAGMIMKEEEILLPMS 228
WP_071136531 151 EYLLFPFLEKH-LITGPPKVMWGKHDETRELLKKAFAALGs-PLTSVEEmrstIEHVLAPAVEMVEGMIMKEEEILLPMA 228
WP_019323639 224 LESFTQDDWLQIASESDAYGYAILKpTEKWIPHRESfdneadadtsdnqladalnqvqdanspegtntkvintpegqfti 303
WP_011684675 229 LERFTADEWAEIWASSPRYGWCLVEpRQGYKPFTSE-------------------------------------------- 264
YP_011802    336 LESLTEAQWGRVRHGEDEIGYAWVTpEGEWTPQAADtp------------------------------------------ 373
WP_013558904 230 LNLLTEQEWYDIYLQSDEYGYCLYApEFEWIPEGGV-------------------------------------------- 265
WP_014225769 229 MDTFTDEEWYKIYQETPEFGYCLFDpTDEWRPDGVQi------------------------------------------- 265
WP_045090168 229 MDTLNEEEWYKVYQETPEFGYCLIDpEDEWAPANMKv------------------------------------------- 265
WP_006930310 229 MDLLTEQDWYDIYLQSPEIGFCLYYpEFEWVPEGGLv------------------------------------------- 265
WP_128425716 211 SEVLEEHEWYDMHKQSYEYEFPYI--QKTWDPEFIKe------------------------------------------- 245
WP_076931146 229 MDTLTEDEWYKIYQETPEFGYCLIDpEDEWAPGGVKv------------------------------------------- 265
WP_071136531 229 MDTLTDEEWYKIYQETPEFGYCLFDpEDEWQPAGVSa------------------------------------------- 265
WP_019323639 304 tfkPKEKEAAADRTTQQPFGNGYLSVEQANLILNHLPLEITFVNKDDIFQYYNDsvpAAEMVFKRTPSQVGRNVELCHPP 383
WP_011684675 265 ------AAGRASVDGGVSLPTGALALEQLIAIFSTLPVDLTFVDANDRVAFFSE---GPSRVFARSRTIVGRMVQNCHPP 335
YP_011802    374 -esLTMEGAATGTPDRVTLGTGTLTVETLDRMLRTLPLDLSLVDAEDRVAYYTD---STHRIFPRSAGVIGRNVRNCHPP 449
WP_013558904 266 ---QQPEERPAAHNGRIQMPTGSLSLNELIGLFTTLPFDVTFVDRDDVVRYFSP---GKERIFSRSRAVLGRKVQYCHPP 339
WP_014225769 266 ------EKQEYITADAIRLSSGVFSIEELEALFIHLPVDITFVDKDDKVGFFSH---SPNRVFERNRSIIGRDVRMCHPP 336
WP_045090168 266 ------EKQTYVQTDGIRLSSGAFNINELEALFQYLPVDITFVDKDDKVRFFSH---SPNRVFERNRSIIGRDVRMCHPP 336
WP_006930310 266 ----ENVEKIKASDDKIHLPTGSFTLEQLINIFKTLPVDLTFVDAEDTVRYFSP---GKDRIFDRSRTILGRKVQYCHPP 338
WP_128425716 246 ------SMAVDGSKGTFRTETGELTMDQMALVFNSLPVDMTFVDENNKVRFFTR---PKDRIFPRSPAIIGRDVKNCHPP 316
WP_076931146 266 ------EKQEYVTADAIRLSSGAFNLDELEALFLHLPIDITFVDKNDKVRFFSH---SPNRVFERNRSIIGRDVRMCHPP 336
WP_071136531 266 ------KKPEYITADAIRLTSGAFDLAELEALFLHLPIDITFVDKNDRVRFFSH---SPNRVFERNRSVIGRDVRMCHPP 336
WP_019323639 384 KVLDKVKKVFELLRNGQRDKVNMWF-QSErlGKFVYVTYAAVRDQAGDFQGVLEYVQDIKPFFELDSEfNRDI 455
WP_011684675 336 RSVDVVERILSDFREGRQNVAEFWL-QFV--GRFVHIRYFAVRSEDGRYLGTLEVTQDVGPIRALEGE-RRLL 404
YP_011802    450 KSVHMVEEILARFKTGERDEAAFWI-ELG--GRFLHIRYFAVRSDEGRYLGCLEVAQDVTDIRALSGQ-RRLL 518
WP_013558904 340 KSVHIVNQILKDFKAGKQDVARFWI-NLH--GKMVYICYYAVRDKEGQYLGTLEVTQDITEIQQLSGE-RRLL 408
WP_014225769 337 GSVHIVEQILTDFKNGKENKAVFWLsNFM--GRFIYIEYTAVRNKNGDYLGVVEVTQDITQLRLLEGD-QRLL 406
WP_045090168 337 GSVHVVEQILTDFKSGKENKAIFWIsGFQk-DRFIVIEYCALRGKDNEYLGVLEVTQDITKLRSLEGN-QRLL 407
WP_006930310 339 KSVNIVNQIIKDFKEGKQDVARFWI-NFG--GRFIYISYYAIRNDQGTYLGTLEVTQDLTDLRALEGE-RRLL 407
WP_128425716 317 DSVHIVEEIVDSFRRGERDTATFWI-NIK--GKKVLIQYFALRDDSGSYKGVIEVSQDITGISQLQGE-RRLL 385
WP_076931146 337 GSVHIVEQILTDFRSGKENKAVFWMsNFQ--GRFIYIEYSAVRGKEGEYLGVVEVTQDITTMRKLEGD-QRLL 406
WP_071136531 337 GSVHVVEQILADFKSGKENRAIFWMsNFK--GRFIHIEYSAVRGKEGEYLGVVEVTQDITQLRRLEGD-KRLL 406
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