Conserved Protein Domain Family
YkfC

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COG3344: YkfC 
Retron-type reverse transcriptase [Mobilome: prophages, transposons]
Statistics
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PSSM-Id: 442573
Aligned: 464 rows
Threshold Bit Score: 197.991
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
NP_436278      20 YQWSKAnpddqWR----DMWGWL-TDL-RVLRHA---WQRVA---SN-----KG--GrtAGVD-GMT-----VGRI-RNR 73  
WP_089673214    1 ----------------------msLSSdLNLELA---WEKTK---RNl-----------SRND-KIFinnpyITEIiDHD 40  
WP_013334746    1 ----------------------mqFPL-NELYYA---WEQVR---RG-----SP--S--PGID-GIT-----TDLF-AGV 35  
WP_005874916  248 IKENRQy---dMSgilgQLFYRVpYDPvAALMLSmahWVHIG----NhtivgNGqiEstPGND-TLYrk--wLSSL-AAD 316 
WP_088619267    1 --------------makgLLELA-MSP-DILDQS---WRRLQ----S---------EhtPWSP-TVS-----RDEL-EHH 41  
WP_015186217    1 ----------------------mdFPL-EDLIAA---WRQVR---RG-----SR--S--AGID-GIT-----TDLF-AGV 35  
WP_127565335    1 ---------------mnaLQk--nFST-KALADC---YSRNRskfRK-----AG--S--AGID-GVG-----LIDF-DDE 43  
WP_114927720    1 ------------------maapanpftpdLLRTA---WKGVR---DG-----VD--E--REAP-SPA-----IARF-EQD 40  
WP_012591153    1 ----------------mDFAKQV-RIA-KTLNKA---WKAVQ---RN-----SQt-S--KSIEtRRE-----VEAF-EAN 42  
WP_015279347    1 --------------mkptLLEQA-MSP-EVLDRA---WRKLK----G---------EhtPWSP-TVS-----RDDL-QHH 41  
NP_436278      74 s----EHRFLVDLQADLRsgAYRPSPARRKLIPKAGkpGQ---FRPLGIPTIRDRVVQGAAKILLEPIFE-AQ-FWHVSY 144 
WP_089673214   41 -----RSEYIEQLSQKLDs-gYSPSDSRTVSFPKKDw--N---VRPASVLKITDLTIYSAIIIELYDDIR-SE-IQWSAQ 107 
WP_013334746   36 -----KKDELIRLQQELIeeIYQPYPARGFYLPKNN--GD---KRLLGIPAVRDRVVQRWLLEDLYLPLE-EV-FTDCSY 103 
WP_005874916  317 rdlpmAEAERQDLLEALRicSYIPQPYHSVNIPKGD--GS---YRQLHIPSAVDLHLQRSLAGILYPITE-SL-SIAQSY 389 
WP_088619267   42 -----FVGHFLALRDEVLagSYRPKPLRQFPMQKPD--GK---SRIITAQYLADKVIQRAILTVLEPKAE-QL-FHDSSF 109 
WP_015186217   36 -----AKEQLYSLQRQLQqeHYAAHPALGFYLRKTR--GG---KRLIGIPVVLDRIVQRLLLEELYLPLE-DT-FLDCSY 103 
WP_127565335   44 -----LTENIADLSKQIIsgAYVHKSLKAFAFLKSN--GK---VRWICVPTIRDRLVQRRVAEVILQGAH-SKiRTEFGF 112 
WP_114927720   41 -----LDANLELHDRELStcEYRPRDLTQVALTE-S--DR---VRVLSVPAVRDRVVARAVLAIATPVVD-PL-LGPAAY 107 
WP_012591153   43 -----SQSNLKRIADQLLhrKFIFPAAKGVPIQKAK--GKrgdIRPLVVAKVEARIVQRAIHDVLIEVPSiRR-YVRTPY 114 
WP_015279347   42 -----LMRHLLACREEVLdgAYRPLPLRQFPVRKPD--GR---QRVLTAQFLRDKLVQRALLTVLEPRAE-AL-FHDDSF 109 
NP_436278     145 GF---RPGR-----NTHGA-------------LEYIRRAALpqkrdedtrrnRlPYPWVIEGDIKGCFDNINHHHLLERM 203 
WP_089673214  108 DR---RFSRil-ldDISENsywmenpfkswkqWNEKSQTLY-----------N-EYEYVLSTDISSYFENVEHRILDSNL 171 
WP_013334746  104 AY---RPGR-----GIQMA-------------VKHLYYYYQ-----------I-QPKWIIKSDIRSFFDSLNWSILLSIL 150 
WP_005874916  390 AY---RKGK-----GAVAA-------------VRRVQHLLDs---------lD-ENHTVVRCDIDNFFDSIPVPSLLQKV 438 
WP_088619267  110 AY---RPKR-----NVEQA-------------LNKAKEHIR-----------C-GRDWLVDADIESFFDTIPHVLLLKRL 156 
WP_015186217  104 AY---RPGR-----GIQMA-------------VQHLESYYQ-----------F-QPTWVIKADIAQFFDNLCHALLFTHL 150 
WP_127565335  113 GAl-kREGA-----EAERT-------------ATKVALALR-----------Q-ESPWVVKSDISAFFDELRRDSVKAAY 161 
WP_114927720  108 AF---RPGL-----GVSDA-------------VQAVARLRD-----------D-GNEWAARLDVDECFPTIPVAYARRLL 154 
WP_012591153  115 SFggvRKEKddsvsAVPAA-------------IDAAMAAIG-----------D-GFSYYIRSDITAFFTKIPKSAVAALV 169 
WP_015279347  110 AY---RPER-----NVAKA-------------LAKVRERVR-----------I-GLDWLVDADIEKFFDSIPHRPLLRVL 156 
NP_436278     204 RKRIG-DRR-VVRLVGLFLKAGVlt--------eDQFLRTDAGTPQGGIISPLLANIALSAIEERYERwtyhrkktqarr 273 
WP_089673214  172 REITD-NEK-LRDLLWKFLARWn--------------RPKGRGLPQGYYPSNILSELYLNRIDKRIKS------------ 223 
WP_013334746  151 EHLKL-DPI-IQQLVEQQLKSGIvl--------kGRYFPRNQGVLQGAVLSGALANLYLSEFDRKCLE------------ 208 
WP_005874916  439 QRTTE-DPF-LTRMLSLWMKSGVvd-------rkQQYARASSGIPQGSPLAPLLSNLYLEDTDRYIAGhi---------- 499 
WP_088619267  157 KPFVA-DNK-AMKLMALWLKQGAh---------qKSLLGKVRGIPQGSVLSPLLCNLYLHDFDQSLSRa----------- 214 
WP_015186217  151 EQLQL-EPI-VLQLIEQQLKAGIvi--------kGQRLFPQKGVLQGAVLSGALANLYLTEFDRQCLS------------ 208 
WP_127565335  162 RNVCR-QRS-LYALIDQVIDVEAvprpgtphkmnESGITRGRGLRQGMPLSPLLAHISLVALDNFLES------------ 227 
WP_114927720  155 QAALD-GQDhVLSVVDFLLDRLVvv--------pRKGRRHQLGLPQGCPLSPLLANLVLAEFDSDLLD------------ 213 
WP_012591153  170 SDAVGhQSE-FMDLFRRAIHVELenmar-lartvNAFpiYDIGVAQGNSLSPLLGNILLYDFDQQMNG------------ 235 
WP_015279347  157 DGFVA-DAK-AMKLIERWLGQGAh---------vRSLLATPRGIAQGAILSPLFCNLYLHGFDRSLDSa----------- 214 
NP_436278     274 ksngvaaaasardsdriAgrcvYLPVRYADDFVVLVSGSLeEAMAEKSALADYLiKTTGLTLLP--E-KTKVTAMTEg-f 349 
WP_089673214  224 -----------------Eg---YDHTRYGDDLKIYCRNRN-DAINMLNKLSELY-RNKGLYINK--S-KTEILTSKEakr 278 
WP_013334746  209 -----------------Kg---INLVRYGDDFVAACQSLG-EAERTLNLITQWL-ERIYLQLHP--K-KTEIYAPDqe-f 262 
WP_005874916  500 ---------------------tTEFIRYADDLLLFLPEKV-DPLNALQDLSEHLkYRKGLKLNR--Df--VVSSIKss-f 552 
WP_088619267  215 ---------------------nIPFVRFADDFLLFTDSKM-NALAAKAYAKNQL-GKLDLNLHP--V-KSRIVQSGph-v 267 
WP_015186217  209 -----------------Hg---LNLVRYGDDFVVVAPDWI-QANRALEQITTGL-AQLYLTLQP--E-KTKIFAPDee-f 262 
WP_127565335  228 -----------------Rg---IKFVRYVDDLVFFGVSKD-EAVRAFEVAKSWL-SERHLELPNirEgKTEICKPSqh-v 284 
WP_114927720  214 -----------------Qg---FPVVRYADDICIPVADEQ-DAWEALREAHHSL-RRLDMAPGA--E-DSQVMSF----- 263 
WP_012591153  236 -----------------Np--dAVCLRYIDDFIIFAKTQQ-LAENMFQKAIHIL-ASHGMSVAK--H-KTVKGLVRdk-f 290 
WP_015279347  215 ---------------------hIPFVRFADDFLLFAPTRS-DAGRAMEHAARRL-ERLDLRLHP--D-KTRVVRSGre-v 267 
NP_436278     350 EFLGFRFsv----------------------hWDKRYGYGPRVEIPKAKAANLRHKVKQLTQRDSISVSLGEKLRGVNAI 407 
WP_089673214  279 KFkdpr-----------------------eiiKQLQPKIVDRIRQEREDRRKKIKAKRDKDSSDSRNYIPYTDGGEIDES 335 
WP_013334746  263 TFLGYLFkk----------------------gQVYAPLPPEPRKKGYPLDPSGMPRRPRPIYIHSFLSQPPKICSLKPKT 320 
WP_005874916  553 SFLGITFca----------------------dGSRSMSRDKKEGLKRKITLALHRDTENFSALSETIHGMEQYYRKLLEK 610 
WP_088619267  268 IFLGQKLpyatr-------------------------------------------------------------------- 279 
WP_015186217  263 TFLGYQFaggtvtapppvvnedseafsesgspSRRKTRQPPKLKSRPPKTCNIVKRSQFPIADLDHYWKEPMTTLYITDQ 342 
WP_127565335  285 EFLGIDI-------------------------YKAKNIYRMRIPSSKFDRLDGRFSEKSFLNLENPAHGEVLSALRFVSS 339 
WP_114927720  264 --------------------------------AQGFSFLGEDFGPRYPPAIEELRVAEPAAKTLYAARQGGRVRIASGRV 311 
WP_012591153  291 EFLGIEFan----------------------gLLRPCSASRHRMILSIDKILISSRDALRGFKKTGELNRQCSFLHTLLK 348 
WP_015279347  268 IFLGETLpgptr-------------------------------------------------------------------- 279 
NP_436278     408 TSGWANYYRYCVGAGRVFVALDWYIGLRLYCWLHKKRPKATPSELWGSKQPSRRRATRRVWREGSVEQHVLGWTPVDRYR 487 
WP_089673214  336 DIREDEEIILLGNAFKKHIEDSDLDNKSLFNYLVRNLGDVNSHYAVPYCLDRIKDGRTQIRRIVDKYFSKLNNRDEIANK 415 
WP_013334746  321 STQPKILTNPKHYFVDTMTTLYITDQGSYLKAQGYQFHIFYQRELRCKIPVNQVSHIVLFGCCNITHGAVRLALTRRIPL 400 
WP_005874916  611 VDIEAIDEVAATVYATHIASLPTSEARKSAKDNLLRLGFLSSETAKQTLREAMRQTVVSSADNFPIKKESEILREQQKRQ 690 
WP_088619267      --------------------------------------------------------------------------------     
WP_015186217  343 GAYLKVEHQQFVVFYQGELRCKVPVNRVSHIVLFGCCNLSHGAVSLALRRRIPVLYLSQKGRYFGRLQTEGQAEVEYLVR 422 
WP_127565335  340 ARKSYSGVYRFLDNWPAFENKIRDYERRSIRIISKRLSDISTKRGGLSPEVLRAFGVAP--------------------- 398 
WP_114927720  312 IVEDKKSNSLVDVPQSHVGRIVCFGSMGLSAGVRAWALSNDVEVVLASRRGTYLGAMVGAGTARASRIRGQIIAAGSERA 391 
WP_012591153  349 VSGIVQGWGAHYWFCKDRSCFDEMDKRIGTMISRYFGVVRDEREGCTNLQKWQMLGLTPLSNMQRRPFVWPKKGEKYISS 428 
WP_015279347      --------------------------------------------------------------------------------     
NP_436278     488 LAWMDMPDFAM 498 
WP_089673214  416 LISMILNEEII 426 
WP_013334746  401 LYLSQRGRYFG 411 
WP_005874916  691 LQERGEIFDLV 701 
WP_088619267      -----------     
WP_015186217  423 QVQCALDPDFT 433 
WP_127565335      -----------     
WP_114927720  392 QAIATAMVEAK 402 
WP_012591153  429 VNPPPPAIPIP 439 
WP_015279347      -----------     
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