Conserved Protein Domain Family
PRK14713

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PRK14713: PRK14713 
bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase
Statistics
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PSSM-Id: 237797
Aligned: 11 rows
Threshold Bit Score: 670.343
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
283458169  18 TLSNPAPGASASGTPRAPQTAQVPQAARVPRVLSIAGTDPSGGAGIQADLKSIAASGGYGMCVTTSLVAQNTCGVREVFT 97 
116670938   2 SPLASSFLPTPASEVARESSPGGTVLRSTPRVLAIAGSDPSGGAGIQADLKSIAANGGYGMAAITALTAQNTRGVRAVHV 81 
119964315   1 --------MTASPYSAVYPLDAPNPGRATPRVLSIAGSDPSGGAGIQADLKSIAALGGYGMAAITALTAQNTMGVIAVHV 72 
50841601   32 TPVEPDLVRTGEGMSEMTISDALAERGTIPRVLSIAGTDPSGGAGTAADTKSIIAAGGYAMAVVTSLVAQNTEGVRAIHT 111
172040057   1 MHHSTLSNQPGTSGDATANTANANPTPAIPRVLSIAGTDPSGGAGQTADLKSIAAAGGYGMSVITALVSQNTHGVQAIEE 80 
184200775   1 --------------------MIATSPAPAPRVLSIAGTDPTGGAGHAADLKSIAAMGGYGLSVITAVVAQNTRGVVDVHT 60 
220912894   3 LLSTTLAIPAATPFPNPSAAALTAAGRDVPRVLAIAGSDPSGGAGIQADLKSIAAHGGYGMAAITALTAQNTRGVTAVHV 82 
258651524   1 ---------------------------MTVRVLSIAGSDPSGGAGIQADLKTFAAQGTYGMAVIASLTAQNTAGVRGVFS 53 
257069838   1 -------------------------------MVSIAGTDPTGGAGTAADLKSITAAGGYGMAVVTAVVAQNTRGVRDIHV 49 
296129483   1 -----------------------MSAASRVRVLSVAGTDPTGGAGVHADLKSFAAHGAYGMAVVTALVAQNTHGVRAVHV 57 
295129641  32 TPVEPDLVRTGEGMSEMTTSDALAERGTIPRVLSIAGTDPSGGAGTAADTKSIVAAGGYAMVVVTSLVAQNTEGVRAIHT 111
283458169  98 PPLEFLTAQLAAVFDDVTVDAVKIGMLGDADTIRTVRTWLSEHPVPVVVLDPVMIASSGDRLLQAEAEQALRDLVPLVNV 177
116670938  82 PPADFLTAQLEAISDDISIDAVKIGMLGDSSVIAAVRSWLEKARPAVVVLDPVMVATSGDRLLQEAAEAALRELLPLADL 161
119964315  73 PPAQFLRQQLDAISSDITIDAVKIGMLGDATVIDEVRGWIEEVRPAVVVLDPVMVATSGDRLLRESAEKALRSLLPLADL 152
50841601  112 PPTDFLVQQLAAVSDDVRIDAVKTGMLGTAEIVDAVATFLDEHRPLVVVVDPVMVATSGDRLLAPDAEAAMREFCRRATV 191
172040057  81 IDHDFVRKQFDSVFGDVTVDAIKIGMLGDAATVALVREALRDNPAPVVVLDPVMVSSSGHRLLEEDAEDAVRGLVADVDV 160
184200775  61 PPVSVLQAQLDAVAQDVELDAVKVGMLGSVETIETVGRWLAAGRAPVVVIDPVMVATAGGRLLEPDAEDALRGILHHADL 140
220912894  83 PPASFLAQQLAAISDDIHVDAVKIGMLGDAEVIAAVRTWLEKVRPAVVVLDPVMVATSGDRLLQESAEAALRNLVPLAHL 162
258651524  54 PPASFLAQQLDAISDDIAVDAVKIGMLGSAENIAVVDTWLATHRPPFVVLDPVMVATSGDRLLDENAESALRALLPRADL 133
257069838  50 PPAEVLAAQLTAVSDDVELEAVKTGMLGTVEVIDTVAAWVAAHPPRVLVVDPVMVASSGDRLLEPEAEQAMIRFCARATV 129
296129483  58 PDVTFLRAQLDAVSDDVTVDAVKIGMLGTRAVADEVASWLTRTRPPVVVLDPVMVATSGDRLLDADAEHAVRALVAHADL 137
295129641 112 PPTDFLVQQLAAVSDDVRIDAVKTGMLGTAEIVDAVATFLDEHRPPVVVVDPVMVATSGDRLLAPDAEAAMREFCRRATV 191
283458169 178 ITPNIPELAVLCEKEPAQTFDEAHEQAANLAAATGTTVIVKGGHLCGQDAG------NTAVFPDGT----CAHVRTPRLD 247
116670938 162 VTPNLAELAMLLNEPLADDWEAALAQGKRLAARTGATVLVKGGHLDGGECP------DALVNTAGLlaqdVVVVPGERID 235
119964315 153 ITPNLPELAMLLGEPEATEWESALDQGKRLAAEYGNTVLVKGGHLPGPVCP------DALVNTSGMlsrdVIEITGPRVE 226
50841601  192 ITPNIPELAVLCQSEPATTPEQAVEQARRWAAETGAAVVVKTGHLNSQRVD------NMWVTTEGA----MHVAPAARVE 261
172040057 161 ITPNVPELAVLTGKDAATDYDAAVAQAQPLARENDTIVIVKGGHLSGERAD------NAVVYPDGR----VDRVPTYRID 230
184200775 141 ITPNLPELAVLAERPVATTWDEALAQGRAVAETFGTRVLVKGGHLAGDTTP------DALVVPGRAe--pAAQYAGARVV 212
220912894 163 VTPNLAELAMLLEEDVQDTWEAALEQGRRLADATGTAVLVKGGHLQGSSCP------DALIGPAGMlsadVVEIPGERVA 236
258651524 134 LTPNVAELAVLVGDEPARDLDGAIAQGKALASSTGAQVLVKGGHLGSAGADgdqlatDALVGPDGS----VTLVPGPWVS 209
257069838 130 VTPNIDELAVLTGSPRASTEEEALAQATAWTARTGASVIVKTGHLEDREVT------NTWVAPDGA----QRRARSTRVD 199
296129483 138 VTPNLPELGVLLGEPTATTWTDAVRQARRLARDAGVTVLLKGGHLDGDASP------DAVVDATT-----VTELDAPRVA 206
295129641 192 ITPNIPELGVLCQSEPATTPEQAVEQARRWAAETGVAVVVKTGHLNSQRVD------NMWVTPEGA----MHTVPAARVK 261
283458169 248 SRNTHGTGCSLSSSLATRLGvellqhaevaehtaeqsvlTSEDTHRALQWSTRWLHESIAAGAGLQVgsGEGHGPVDHAA 327
116670938 236 TMNSHGTGCSLSSAMATAQA-------------------RLGDWEESLRTVKPWLQGALREAGALDV--GTGNGPVHHFH 294
119964315 227 TRNSHGTGCSLSSALATVQA-------------------RRGDWEVSLQEAKSWLLGALTTSGALEV--GQGNGPVHHFH 285
50841601  262 TTNTHGTGCSLSSALATRLG-------------------AGDTPGDALAWVTDWLHEAIQYGSALNV--GKGHGPVDHSH 320
172040057 231 TRNTHGTGCSLSSALATRMG-------------------LGEDAGTALRWSTRWLHEAIENGEKLQVgdGTGFGPVDHSH 291
184200775 213 TRNTHGTGCSLSSAVATVVA-------------------RTGDWAQGIDTARQWLRGALRAADTLHV--GHGNGPVHHFH 271
220912894 237 TRNSHGTGCSLSSAMATVQA-------------------QVGNWEAALREVKPWLAGALAASDVLEV--GTGNGPVHHFH 295
258651524 210 TTNTHGTGCSLSSALAALRP-------------------QRESWAAAAVDAKAWLTGALAGGAALGV--GQGRGPVDHLH 268
257069838 200 TTSTHGTGCSLAAALATRLG-------------------AGHSPAAALEWATAWLHEAIAHGASLQV--GAGHGPVDHAH 258
296129483 207 TTSTHGTGCSLSAAVAALRP-------------------RRPDWVTAVREAKEWLTGAIAAGEALAV--GSGRGPVDHLH 265
295129641 262 TTNTHGTGCSLSSALATRLG-------------------AGDTPGDALAWVTDWLHEAIQYGSALNV--GKGHGPVDHSH 320
283458169 328 RARRLEAAASaypwhhllattdsegntldg-------------tsperllpvspvpageavvkPAGPWTAALWAAGGETW 394
116670938 295 HLAPKGSDAP-----------------------------------------------------PEGRFAAVLWQDAGPDL 321
119964315 286 HLQQAS---------------------------------------------------------KPGAFAATLWKEAGPEL 308
50841601  321 RARRLAEDASavawfapidplespq-----------------------glvvsaepapdavvaPAGPWTTALWQASGDIA 377
172040057 292 RSRRLEQVASseiwphlrgelpe---------------------------gqgyaaaptphlePAGPHTRRLWELTGQVW 344
184200775 272 HVQDLVTDPTflagacad-------------------------------------daaglgsgQGRPFTDELWDESAPVR 314
220912894 296 HIRKAL---------------------------------------------------------RPGDFTAQLRKDADVHL 318
258651524 269 AL-------------------------------------------------------------FPATFSTQEWSRIAPIR 287
257069838 259 RARRLAAAGSaepwlgagevparletpealsvgrsrpgpgtaedstpaddsptvqpvvpalvpAAGPWTAALWAAGAPLA 338
296129483 266 HAPGL----------------------------------------------------------GARPFSAEAWDHVADLR 287
295129641 321 RARRLAKDASavawfapidplespq-----------------------glvgsaepspdavvgPAGPWTTALWQASGDIA 377
283458169 395 HQILDLPFVRALGDGTLDEDLFAFYLDQDALYLRDYSRALATLSARADTAEAQVHWAAGAHEAIAAESQLHEGWLANR-- 472
116670938 322 DAVYELDFIRGLADGSLTEQHFAYYLAQDAIYLNGYSRVLSRAAAIAPTEVEQLFWARSAQQCLEVESELHRTWLSTR-- 399
119964315 309 ESIYGLPFIQGLQSGELPERDFNYYLAQDAIYLNGYSRVLARAGALAPTEEEQLFWAKASQQCLEVESELHRNWLSTR-- 386
50841601  378 RRIEDSDFVAVLVDGTLSKPAFEFYLGQDAQYLTYYSRALASLAARAVDPEESVWWAQSSQACLVEEAELHRSWLGDH-- 455
172040057 345 QEIMELPFIRGLASGRLPEEDFNFYLAQDALYLNRYSRALAELSTKAPDSAGQVMWANSAAGCIEGEAELHRSWLKGRgi 424
184200775 315 ERIAALPFVVALGDGTLDREAFEFYLDQDMQYLEFYSRALALLAASAPDEDSRELFASASAAVVTGESALHRARLGDRq- 393
220912894 319 EAIYALDFIEGLASGTLPENEFAYYLAQDAIYLNGYSRVLARASALAPTEAEQLFWAGSARQCLEVESELHRSWLSTR-- 396
258651524 288 AAIETMPFIVALADGSLPWVNFRFYLAQDAQYLREYARCLARVAALAPDQDAQEFFAHSSAAALEAEMGLHRTLLTAHge 367
257069838 339 GQIAECGFVRALVDGSLPSPAFDVYLAQDALYLGRCSRALAALGAATEDPAGGEFWTQSARHCLAIEAELHRSWLGGLp- 417
296129483 288 AACDDLPFVRGLADGTLRVEEFEQYLYQDALYLAQYSRVLARASQLATEPAAQAFFARGASRCLEVETRLHEDRLARAg- 366
295129641 378 RRIEDSDFVAALVDGTLSKPAFEFYLGQDAQYLTYYSRALASLAARAVDPEESVWWAQSSQACLVEEAELHRSWLGDH-- 455
283458169 473 -ARL---GGPSPITMGYTNFLRASAAGDDYVVGAAAILPCYWLYEEVGAVLSSQ-----NHADHPYAEWLSMYGGEEFAA 543
116670938 400 -NVD---TALGPVTKSYVDHLLASSVSGSYGVLVAAVLPCFWLYAEVGATLHGQflaagSAPDHPYAEWLRTYADEGFAA 475
119964315 387 -EAS---TATGPVTKSYVDHLLATSASGSYAVVLAAILPCYWLYAEVGRQLHASyvdagAPADHAYAEWLKTYADEDFAA 462
50841601  456 --ID---VVAGPVTLAYTDFLLARALGDDYVVGTAAVLPCFWLYAHLGAKVPHV------PDDHPYASWLQTYGDPEFVE 524
172040057 425 eDASanpVAPSPVTLAYTNFLVATAAVEPYVCGVAGVLPCFWLYAEIGLELTRA-----NHDAHPFKAWLDTYADEEFLS 499
184200775 394 ------pLPPSETTSAYADFLLARTGQDGFAVGAAAVLPCYWLYAHVGSELSARar-aaGLDGHPYADWLQTYEDPAFQA 466
220912894 397 -TVR---PQLGPVTKAYVDHLTAASASGSYAVLAAAVLPCFWLYADAGKALHARfladgEPAGHPYAEWLRTYADEDFAA 472
258651524 368 sLSG---IETSPVTTAYLDHLHRCCATGSYAEAAAAVLPCFWLYQHIGERLGVLqaqrsSADAHPYAAWIETYADPAFAA 444
257069838 418 aDHD---TAISPVTSAYTDFLLVHALGSPAPVAAAAVLPCFWLYAQVGGGLDDV------AAEHPYGAWLETYRDPGFVE 488
296129483 367 hRWS---GPASTATTAYVDHLLAVAATGSYAEVVAAVLPCYWLYADIGARVLARa---gDLSTHPYRDWVGTYGDPEFAA 440
295129641 456 --ID---VVAGPVTLAYTDFLLARALGDDYVVGTAAVLPCFWLYAHLGAKVPHV------PDDHPYASWLQIYGDPEFVE 524
283458169 544 DVARSLAEVERAFEAASPAQRVRAAQAYLSACVYEREFFDQAHRALR 590
116670938 476 ATRQAVRIADDAARAASDAERQAMRVAFRQSCRYEVEFFDAPRLHAA 522
119964315 463 ATRKAINFTDAAAIAGSEMERAAMMDAFIQSCRYETAFFDAPRLFAQ 509
50841601  525 GASHTIGLVEKAFQNASAVTRARAAHAYLTACRHELEFFDQALRV-- 569
172040057 500 GAREAIQRTEAAFEAASEEEREAATSAYLNAAVYEREFFDQADRRW- 545
184200775 467 ATEAVREIVDRAASCADPATREAMRRAYLRACRLELAFFDQSAQRGG 513
220912894 473 ATRRAIAMVDDAARKASDDERQAMATAFRQSCRLEVEFFDAPRLHS- 518
258651524 445 ATTSAIGFADRAFQAGSPAERDAMIAAFERSSRYEWMFFAQGTDLPA 491
257069838 489 GVRGALEQVERELAAATPEVRAEAARAFLLASRHELEFFEQATRLDP 535
296129483 441 ATADACAFADAAARDVGAGTRARMLAAFTTSCAHEVAFFDQVRAGAG 487
295129641 525 GASHTIGLVEKAFQNASAVTRARAAHAYLTACRHELEFFDQALRV-- 569
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