Conserved Protein Domain Family
T2SSF
?
pfam00482: T2SSF 
Type II secretion system (T2SS), protein F
The original family covered both the regions found by the current model. The splitting of the family has allowed the related FlaJ_arch (archaeal FlaJ family) to be merged with it. Proteins with this domain in form a platform for the machiney of the Type II secretion system, as well as the Type 4 pili and the archaeal flagella. This domain seems to show some similarity to PF00664 but this may just be due to similarities in the TM helices (personal obs: C Yeats).
Links
?
Statistics
?
PSSM-Id: 425708
Aligned: 247 rows
Threshold Bit Score: 31.1515
Created: 21-Mar-2022
Updated: 13-Oct-2022
Structure
?
Aligned Rows:
Download Cn3D
PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
Q8U3X1 337 FIRSLSSSLAaSGASLLLVLKYLSAHD--FGTLTEDIKALYRRLAIRV-----DQD---RAWDyfiaetgSWLVgMF-SE 405 Pyrococcus furiosus
Q9HR80   4 TVAFMYALSR-SGMPLAEVLRILARNQpvYGAAAEEMAVAVTDIDNYG-------AdiiTALErv---gsRTPSdDLa-E 71  Halobacterium salinarum
O29267 144 AIIFMYSLSK-GGMSLVQILKALADNHevYGEVSKEASRILWEVEGLG-------KdlrTALAea---vdTTPSdNF-KE 211 Archaeoglobus fulgidus
Q8TJ14 165 ataflyvlqRgGGMTIFDIMKSLSKHShlYGTASHEFGNIIRDVEYFGk----DLQ---DALWna---adRTPSeQF-KD 233 Methanosarcina acetiv...
Q8TU41 139 aVTYMYALTK-GGMSIYDVFRSLSSYThiFGTSAEEISYIVRDMDYLGkdfitALK---EAKE-------RTPSeRF-KD 206 Methanosarcina acetiv...
Q97VE7 214 FVTLITIINA-SGTTIYEGMRKILQFPi-FKAMKKEALLIIRDIEFFG-----KSP---LDALeh---rsRLTLnRDySW 280 Saccharolobus solfata...
Q9Y9T1 145 FAAYLSIMGR-GGVPVSLVIDRVASLKi-FKALREEAEMIRTKIRLLGk----NPL---DALEeh---vlDSPSsVF-RD 211 Aeropyrum pernix
O29599 129 AVNMMLGMAK-GGVPLISIFRFVAENReiFGEISREFDKIVTLVEIFG-------YdmiTAMKyv---adTTPSeKL-KV 196 Archaeoglobus fulgidus
Q8TLD9 208 ALSYMSVLAS-GGSSPLDVIRRVAAED--YGEISRELSKVMYRIDALG-----EDG---NTAMsy---liQNTSsEHlRA 273 Methanosarcina acetiv...
Q9HJR5 117 ALAVAYGLSL-SGVPADTMISELAGIKe-LGEFAKESQRVNSFMYAMG-----YDF---LSALer---seKVSAsPDfSR 183 Thermoplasma acidophilum

Q8U3X1 406 IFRESLRLGAEPDYVGKVISRNFERIVRLRRKRQQSISNFIGIILGLTGAFAFSLAA 462 Pyrococcus furiosus
Q9HR80  72 FTENLGSILQSGSDLPAFLKQEYEYYAEEAEATQSQFLELLATLAEAYVTVLVAGPL 128 Halobacterium salinarum
O29267 212 FLHGLITIIDSGGDITRYFEERAEFYFERARQDQKSFLEFLGLMAETYITAFVAGPL 268 Archaeoglobus fulgidus
Q8TJ14 234 LVDGLISIVSGGGDITLYLKNKTDLYKSNANKEHKRFLDTLGLLAEVYITVFVVGPL 290 Methanosarcina acetivorans
Q8TU41 207 FVDGLI-LVSSGGTITEYMKNKSEQYQEMADLANRNLLKRLDVLAEVYVTAFVAGPL 262 Methanosarcina acetivorans
Q97VE7 281 FLAGYSSIIRSGGDIEAYLFQKAREFLNWLQFRWRFYSERTSFLGELIVILFLIFPM 337 Saccharolobus solfataricus
Q9Y9T1 212 FILGYTTAVKVGSDVIHYLEIRTQDLFERRLNDIRLLAERMTLYLEIYLVVAVIATI 268 Aeropyrum pernix
O29599 197 FLENFINVYEGGGDVVEYLRAKSEQLLTERETYYTLFFETLQVYAEIYLALFIVAPL 253 Archaeoglobus fulgidus
Q8TLD9 274 VCIDISNAMQAGGGLQAYLELKSKELMEMRRQAQKAFVDSLSIYGEGYLSGIVMSVV 330 Methanosarcina acetivorans
Q9HJR5 184 FVAGIRLSIILNSDLTAFLRDRLDYYVRVQENKSKLSLDSLGLAAESYVAVAIAFPI 240 Thermoplasma acidophilum
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap