Conserved Protein Domain Family
TMEM154

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pfam15102: TMEM154 
TMEM154 protein family
The function of this family of transmembrane proteins has not, as yet, been determined. However, it is thought to be a therapeutic target for ovine lentivirus infection. This family of proteins is found in eukaryotes and members are typically between 138 and 320 amino acids in length.
Statistics
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PSSM-Id: 434459
Aligned: 5 rows
Threshold Bit Score: 114.267
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EFX81560       9 DNQTqts---------------tfPKITSTALPTTTLTTESATASTTASTtDPSFKpqiqttanVQLSSGELSNKSDSQA 73 
XP_005629397  50 SEEP--------------------EQSADMPLEVYGREDFNTNATFPTVT-TETLP--------ANTSFIDFDDDADQLE 100
AAI62521      21 SEESpeiteeelvvvttkaevqdkENNGDVAGSGYGMSQTTSDLGSIQNSeSESFNtee---tkQTEAEADTDNEENDLN 97 
NP_001102023  24 DEDS--------------------EYSGHSTTEEDTAEEETTRA-LATVT-TEALA--------ESANSTHIHGTSNQVE 73 
Q6P9G4        24 YEEL--------------------ENSGDTTVESERPNKVTIPSTFAAVTiKETLN--------ANINSTNFAPDENQLE 75  human
EFX81560      74 NMLIIIIPSVALIILLIVGAILIQKKCQTRRKDKETSEVESDQQQQHAIDYDNLIQStysirldpegkcFYENSVAESPA 153
XP_005629397 101 FILMVLIPLILFALLFLSVIILVTRYRRKRAKQEPYSPGSQSALQTYELGSENIKVP------------IFEEDTPSVME 168
AAI62521      98 IVIMIIIPLVLTIVISMIVCVVI-ICRRWRIKDDTKEDAYLD-----DDDHEKVPMP------------MFEDDIPSVME 159
NP_001102023  74 FILMVAVPLAALLILLFAILIVI-YFKSRRPKQD-------------DLGGETLKVP------------IFEEDTPSVME 127
Q6P9G4        76 FILMVLIPLILLVLLLLSVVFLATYYKRKRTKQEPSSQGSQSALQTYELGSENVKVP------------IFEEDTPSVME 143 human
EFX81560     154 IELQSISSPVyATLEFLPNNSIV 176
XP_005629397 169 IEMEELDKWM-NSMNRNADGECL 190
AAI62521     160 LEMEDLENWMaKDGGKKVDTGQI 182
NP_001102023 128 IEMEELDKWM-NSMNRNANYECL 149
Q6P9G4       144 IEMEELDKWM-NSMNRNADFECL 165 human
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