4XD9


Conserved Protein Domain Family
RRS1

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pfam04939: RRS1 
Ribosome biogenesis regulatory protein (RRS1)
This family consists of several eukaryotic ribosome biogenesis regulatory (RRS1) proteins. RRS1 is a nuclear protein that is essential for the maturation of 25 S rRNA and the 60 S ribosomal subunit assembly in Saccharomyces cerevisiae.
Statistics
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PSSM-Id: 461494
Aligned: 143 rows
Threshold Bit Score: 100.68
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4XD9_D        31 PYTFDLGHLLANDPNPLELPKSe-PLNASLKATARDGVQSLLNQLLTtCPITSS----QqG----------VL-LTLPAP 94  Aspergillus nid...
ESS29858      25 AMESHLNFLLSIDFSPV-------LHTDDLSDLTRQNAQSMVAQLCA-LPHETTd---D-G----------LL-VALPPP 81 
Q5CQC9        10 PLEVCLSNLIGIDISSI--------NETEINKSGANNLQLMLNSIWSdLSKENTk---D-G----------TV-VSLPSN 66  Cryptosporidium...
EEA06862       9 PLEYCLSNLVGIDIDEI--------REDEIDRISVNNTQLLLNSIWKdIPREMTn---D-G----------LM-VILPMK 65 
XP_001610749  11 NLEYCLRNLIAIDATPVDASGC---DAESLTNLSRDNTQLLINRIFS-LGRTTTe---D-G----------IF-ATLPKE 71 
Q4N774        11 NLDYCLKNLIAIDATPTSTELL---HNNNLLKLSCENAQLLVNKIFG-LNRTTTs---D-G----------VF-AELPST 71  Theileria parva
Q8IIB5         2 DIDFCSHHLLAYDNSII-------NDENEIKAKVEQNLPLIFSKINK-LQKEKEd---EeD----------II-YSVTNd 59  Plasmodium falc...
XP_001615363   2 SIEFCSQHLLAYDNSII-------TSENDIKSKAEENLRRIIQCMDA-LKNGKDd---LgE----------PA-YQMTKt 59 
Q232H5        29 NVSSDLGILTIFDSNEIPKNSDgtISEQTLLERTRLNISRIFNKMLSmKTLQNAerdaKdEelqihdfskgAYeLKLPNK 108 Tetrahymena the...
Q4DA55         3 EHQLDIGLLCITNVSLISGPQR---PEEDLHESATHAMRLLLNECQE-LPTTKKr-----Gkfd----astTL-VQLPQP 68  Trypanosoma cruzi
4XD9_D        95 STI-----L-PRHKPLPTPKPPTKWELFARKKGIgkySnKpgaalaDKerRKKLVYDEESGEWVPRWGYKGKNK---DDD 165 Aspergillus nid...
ESS29858      82 -AKnstfkL-PRMHPAPAAKKLTRWEAFAKEKGI------------QKrkRSRLVWDANTKDWVPRWGHKGIQQ-----M 142
Q5CQC9        67 QEI-----LlPRAYPLPTKKEKTRWEKFAELKGI------------KKrkRSRMVYDPITDDFVPRWGRNSIKKiqkKHN 129 Cryptosporidium...
EEA06862      66 QII-----QfPRVYALPEMREKTKWEKFAEMKGI------------KKrkRSRMIYDPVTDDFVPRWGKNSIKKiheKHN 128
XP_001610749  72 NGI-----VmPRMYPLPKPKPKTRWQIFAEARGI------------KKhkRSRLVFDKSVNDWVPRWGYKSIKKg-pLHA 133
Q4N774        72 DEI-----VmPRVFPLPKPREKTRWEIFAELKGI------------KKrkRSRKVFDPTVNDWVPRWGYKSIKKn-kLNK 133 Theileria parva
Q8IIB5        60 ni----fnM-PRYSRIPKEKKKTKWQLFAENKLR------------MKknKSGLIYDKVSKGWVRRFQKKQIKLneqK-N 121 Plasmodium falc...
XP_001615363  60 nh----fnL-PRYSRIPKEKKNTRWEIFAKKKLM------------KKn-KSGLIYDQNSKGWVRRFQKKQMKInedK-A 120
Q232H5       109 VSV-----F-PRQKPIPKEKPLTRWQKFAKEKGI------------EKkkRGRMVYDENVQDYVPRWGAYSVKKnedK-F 169 Tetrahymena the...
Q4DA55        69 VML-----L-PREKAPPRPKPLTAWEKFALKKGI---AlK------RK--KSNRVFDEEKKVWKDKWGKRAREEre--kH 129 Trypanosoma cruzi
4XD9_D       166 QWLVEVK------------------------------E------KDWkkeeeaaakgssiRGMSRAERKERIRRNERKMR 209 Aspergillus nid...
ESS29858     143 NALAEAViedkdgeyvgrrgrdrgvkklgkrskdaqkRrtsqqvECP-------------FEAKAKEKKLRQAKQKLREL 209
Q5CQC9       130 EAIIEIKgn--------------------------mdEn-----KDP-------------REAINLKRDMMINKQRLREL 165 Cryptosporidium...
EEA06862     129 RAVIEIKnn--------------------------idLy-----EHP-------------REKISREKEVAKNKQKLREM 164
XP_001610749 134 PPIVEVTgs--------------------------kvPp----dVDP-------------FEAASRKKSERKTRQKIREI 170
Q4N774       134 PPIMEVKpg--------------------------sdD-------NV-------------LDLESAKKSVMKSKQKLREL 167 Theileria parva
Q8IIB5       122 NFVHEYK------------------------------Nked-iyEDP-------------FEKEQEEKDIKKMKQKMREL 157 Plasmodium falc...
XP_001615363 121 NFVHEYK------------------------------Psdn-iyEDP-------------FERMEEEKEIKKMKQKMREM 156
Q232H5       170 TPVIEHKag--------------------------tdPy-----EDP-------------FLRKSLEKRLAKEKQKMNEI 205 Tetrahymena the...
Q4DA55       130 DWLREVGpn--------------------------yvPqe--egGDP-------------FLDDRRAKKVRLEKQKKKEE 168 Trypanosoma cruzi
4XD9_D       210 ANE 212 Aspergillus nidulans FGSC A4
ESS29858     210 RNT 212
Q5CQC9       166 KNK 168 Cryptosporidium parvum
EEA06862     165 KNK 167
XP_001610749 171 RNK 173
Q4N774       168 RNK 170 Theileria parva
Q8IIB5       158 KNK 160 Plasmodium falciparum 3D7
XP_001615363 157 KNK 159
Q232H5       206 RNK 208 Tetrahymena thermophila SB210
Q4DA55       169 HNK 171 Trypanosoma cruzi
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