Conserved Protein Domain Family
SiaC

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pfam09345: SiaC 
SiaC family regulatory phosphoprotein
This entry represents the SiaC family regulatory phosphoprotein which undergoes a regulatory phosphorylation at Thr-68 of founder protein PA0170 from Pseudomonas aeruginosa, but in more distant homologs, T can be S. Also, it is part of motif NTSS, so may contain more than one phosphorylation site. Phosphorylation causes regulatory change to protein-protein interaction, in a pathway that seems broadly distributed, involves a diguanylate cyclase, and in the case of Pseudomonas aeruginosa affects aggregation and biofilm formation responses.
Statistics
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PSSM-Id: 430544
Aligned: 135 rows
Threshold Bit Score: 89.0961
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q6D887        12 ISGTSCTPAVDFHFDTHRLYLSGESYPENAAAFYRPLLTEIQAYLHALttcaetmppdealPSIEIHVSLIYFNSSSTKM 91  Pectobacterium ...
EAY31695       6 MKDKEGKSYILFNRHTNLFEIYGED-SEHITAFYQQVKDWLEAYIQVSh------------KPISVNLQFLQYHSSSYAA 72 
WP_002705198   6 ITQEKYTPYISFNTDTNIFDIAGESYSEDAFVFYQALLKWLSDYLKVNq------------RPITLNFRLLYFNTSSSQA 73  Microscilla marina
WP_002699191   6 IPEGNYTPYICFDTDTNVFEVAGESYSEYTLEFFEPVLSWLSGYLAQNs------------QSLTFNFRMNYFNTSTSRR 73  Microscilla marina
EAY30721       6 IESTPYTPKVWLDTKTNIFEISGESYSDDTVAFFEPIMEWLQEFLTKNt------------QPIEFNFCMNYLNTGTSKR 73 
EAY24114       6 IEAGDYSPKVSFDTSSNVFEITGDSFGEDTLRFFNPIVDWLQRYLKQNn------------RFIEFNIQMNYLNTSSFKR 73 
EAY31672       6 VAEKYYTPQVSFNIENSLFEITGESFSEYSMDFYEPILSWLEAYTQQYs------------QTILFNFKVSYFNTSSSRR 73 
EAY24947       6 IPENQDTPQVSFDVATQVFEIKGESFGLCSMDFYLPIIQWLDAYTKQHq------------GTLTFNFKLLYYNTGSSQR 73 
EAY24945       6 IAEKHDTPQVSFDANTKVFEISGESFSEYSMDFYLPIIQWIDAYTKQYe------------GPITFNFKLLYYNTGSSQR 73 
EAY29210       6 IKGYACSPTVYFNDQTGELTLDGEYYQEYDVAFFKPVYDWLDGYLRKKg------------RKITVNLKLSHLNSSARRR 73 
Q6D887        92 LFSLFNLLNQAAEQ-A-LSIALYWYYDKDDDIAEEFGEELHIDFPAlTFHSTIL 143 Pectobacterium atrosepticum
EAY31695      73 LLQILQLFNDLYTN-KkILIMINWFINCSDMKTMKDVKTIKSKVGVlPLNILKV 125
WP_002705198  74 IFHILEMLEDYAEReN-VDVQVNWYAKPNDSSMMEDGLYYQDNFDAlSFNMQAL 126 Microscilla marina
WP_002699191  74 FFEILKMLEDFYHQqN-NEVVIHWYAKSNDLDMIEAGEDYKDDFATlPFHISVQ 126 Microscilla marina
EAY30721      74 FVMIISILEDYYKSsK-VWTEVNWFVHTDDADIMTIGEDFQEYFETiPINIKFI 126
EAY24114      74 FNEILAMLERYYMAtK-TLVKINWICNQDDDEIIDYGEDIKEFFENlPINIHIK 126
EAY31672      74 FYEILKILDGYHKAaK-GYVMVNWFASPDDMDMIESGEDFKEDF-DmPFEIVLK 125
EAY24947      74 FYEMMKLLERYHQSgR-GQVKINWYTTSDESSIIEAGEDFQASI-QiPFEIVLQ 125
EAY24945      74 LLEIMQMLDQYHNSgK-GQVKINWYSLPEEYRMIEAGEDYQATL-KvPFEIIEQ 125
EAY29210      74 IDQILECLQDYHTShK-GKVMVKWFYFDTD--TKEEGIELAETFNNlPIHVLPV 124
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