Conserved Protein Domain Family
spore_ger_x_C

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TIGR02887: spore_ger_x_C 
germination protein, Ger(x)C family
Members of this protein family are restricted to endospore-forming members of the Firmicutes lineage of bacteria, including the genera Bacillus, Clostridium, Thermoanaerobacter, Carboxydothermus, etc. Members are nearly all predicted lipoproteins and belong to probable transport operons, some of which have been characterized as crucial to germination in response to alanine. Members typically have been gene symbols gerKC, gerAC, gerYC, etc. [Transport and binding proteins, Amino acids, peptides and amines, Cellular processes, Sporulation and germination]
Statistics
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PSSM-Id: 274338
Aligned: 36 rows
Threshold Bit Score: 242.926
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
novoz:BL01752   3 RIVKIVLLLAAIVLLQGCW-DKRELTDLLLITAIGIDKGKD-TDYELs---yQIVNPINVTGGLQggqggdrppiSSYSV 77  Bacillus liche...
BAD64540        3 KW---LLALCCVLVLGGCApRTKVIEDIQLIQAIGYDYVNK-NEFRSvagslIVLPSEETLPQTK-----------VFTA 67  Bacillus claus...
BAB05905        3 RLKKSILLILVAGFLTGCW-DERILEELAMITILTVDVAEEdSPYLIvsatfPEFSKRAKEPETL------------IST 69  Bacillus halod...
AAS39634        4 KRVKLLFILCTSSLLSGCW-DQEPLREARLAYSIGSDITEE-NKLQQt---iELVKSSSGEQSSFe--------nEIHSA 70  Bacillus cereu...
BAC12437        2 RKTELFLIFFILPLLAGCW-DERFLKNSRTVYLSGFDLDEN-GDYQTts-iiRDMNISESSRGEIsi------snKLVTG 72  Oceanobacillus...
BAC14722        5 YWLKLLCTLLTLIILSGCW-DSRDINYRSMPIMMGVTKEED----LFh---vYFIIPVSVVSEQRn--------lAKVDG 68  Oceanobacillus...
AAK78622        4 KITTICSIIMCCVMLTGCF-NYKDIDNVLFVTTVVFDIDDD-NNVITylevfQPIKSMVKGQQGQq--------rLVFRG 73  Clostridium ac...
AAO36913        5 KKRIISFILCISILFSGCY-SYKDINKVLFVTSFVVDIDNN-NEPIIyletfKPYRSNISGSEKGq--------rIVYRG 74  Clostridium te...
BAB80355        6 VIASLLSIIIMSTMLIGCY-NYKDINRVTFVTSLIFDENEV-GNIDIyldcvKPYRSSNESSDKGr--------rVLYKG 75  Clostridium pe...
AAS41664        4 NKRIVVFLFMMCTFLTGCW-DQRELHHVLYINSLGIDFKDN--NYIIrpqfiNFSNIAKQEGSTTrny----sqaYIGKG 76  Bacillus cereu...
novoz:BL01752  78 TGNNLTEMSRHASAKMSREIYYSHTNLVVVDEKLAKeEGLIKILDVLDRDTDFRTTATIIISRGqKAKTFIRTLTPIDKI 157 Bacillus liche...
BAD64540       68 TGNTSRITQKKMQAKSSKYMVVGRIGLMLFQDRLAE-DGIFYFLNVHQRDSMIGRNLRPAIVEG-KTFDLLSKNYQLDTT 145 Bacillus claus...
BAB05905       70 KARSLREAMEKLNAQTDKKIVQGQIQVVLLGEEFAR-GGIQSTLDTLYRDVDVSAALYVCITEG-RADELIARAFQDKPM 147 Bacillus halod...
AAS39634       71 TGHNIRDTSDALKKNVTGNIRYFKYGVQLLGTKILK-KGILPYLDVSFRDPTNPTALVKLIAVDgETSKILEKKKVGNLL 149 Bacillus cereu...
BAC12437       73 KGGSIKEASMTIDQSVPGNYDPAKGRTLILGNDVAK-GDIYNVLDPLYRDPRVDLNAKIAVTDN-SANGIITHISENEVE 150 Oceanobacillus...
BAC14722       69 KGATVLDATEQIRKKIETTIDLEHIDFVVIDEKLGE-EGIEKIINTFIRMRDMPASPAVAFIDE-DMNKYMEMMISNFEE 146 Oceanobacillus...
AAK78622       74 TGKTAFEALNDINLHCSYELNFTQVKAYIYSEKAAK-KGIKPFVDLVRRRIQFYLRPYVATFIG-NVEELMKGGFKENEY 151 Clostridium ac...
AAO36913       75 TGKTVHEVIRNIGLSSSFRIDGTQSKAIIFTTKAAE-YGIDKFIDFFHRHQEGLIRQYIAIYDG-DVEKLLQTQIKSEEY 152 Clostridium te...
BAB80355       76 TGKTVLEAIKDINMYSSSKLDFTQCKGYIFTEKAAK-NGIRKYIDIINKNQEFMIRPYMFVLFG-SPEELLNDVTVDEEY 153 Clostridium pe...
AAS41664       77 KGFILDEAAFDFYKGAQQEISWEHLKTIVVTERFLKhGDINQFNDFFSRFFQFRDTMWIFGTKE-PLENILANNNILNIS 155 Bacillus cereu...
novoz:BL01752 158 PSNKVNKTLQFTEEHlGEHMKTSVQDVIKCLTSKAKHPIISSFKV--TGNKekgekmenvqstspeaiVEADGLAVIKEG 235 Bacillus liche...
BAD64540      146 VYQYLNELLEQSERE--IYPRVTLHTALYQYYAEGTDMFLPIIKG--NDDH-----------------ARVTGLALFKED 204 Bacillus claus...
BAB05905      148 DGFYLSRLIQKQREV-NMLPATPLHQFQSEYLSKRTDPVLPYVHL--GKNE-----------------AIAAETAVFFND 207 Bacillus halod...
AAS39634      150 IGDFLKKKVKSLEDM-SVFPKETLETAATKMLDPGKDFTLPSIKI--KGKE-----------------VITDGLALFNKD 209 Bacillus cereu...
BAC12437      151 KGEYLYELIHSSEKH-SVIQDITLRSIRTYLFDEGKDFMLPYLSKdeEDNE-----------------VKINGAALFHDH 212 Oceanobacillus...
BAC14722      147 VGTPIFGFLEKQVGWdIYDPEVSLWELYRGINSYTTDIAVPLIGS--NKDLt----------------MDYLGASVLKNG 208 Oceanobacillus...
AAK78622      152 VGFLLSQLIINTGASsRAV-EIQYNDFLNKRINSDRSVVMTAIDIrsAQNKn---------------sVELDGGAIFKND 215 Clostridium ac...
AAO36913      153 IGLFLADLMDNIKVSsKAV-KLSMNDYLNERVMESTACIMSLIRL--DETQme-------------nlITIDGGAIIKND 216 Clostridium te...
BAB80355      154 LGVFIDDLVQRMNKSpRVI-AIDANDYLELRTNYGNLLVLGALSI--RDDMee-------------krLELSGGALLKNE 217 Clostridium pe...
AAS41664      156 QLYTIINLPKEITKQyTIIDPLPLYKFQRNYYEPGMTTRIPFLAT--TKAYwkkgh-------tsfpmLKFSGYGFISDK 226 Bacillus cereu...
novoz:BL01752 236 KLVNW-LEGKTARGVLWLRN-KISRTYLTIPMNHe-----rDAVTFDVIRQ-KTKIGSHLKNGKP-AISVDVAMEGDIGE 306 Bacillus liche...
BAD64540      205 RYIDK-LNVHEASFFKLLSE-PFRGGFYQVQISSd------SFASLENVQA-TPQYTITKDDNGL-HVSILVYMKGVVSE 274 Bacillus claus...
BAB05905      208 RFVES-LNSMETQLLVMLRN-DGTSSQFTKEIESgs---pfEQMTISFVDS-HTTVDVEERGGEGwHFNVNLRLSAELTE 281 Bacillus halod...
AAS39634      210 KLTGH-LPLKQSVLFVLLTGkMGTSARITQKLTSdeskktsDYLTMEISNR-KLKRDLKITTDKKgNVYAHIKLQLKVIA 287 Bacillus cereu...
BAC12437      213 SFTGQfLSPAESTLLLLFMEtQSKKALLTEQLDKka----gGSVSYNVKSV-SRKLKLEKKE----KVHADIMLQLDVEI 283 Oceanobacillus...
BAC14722      209 KIVDT-ISSVEVMIMNLLDNeEVIKTFVTID----------DTTNVELVDR-DVNYDYNKRGEEI-DLTIKLEFVLIVAE 275 Oceanobacillus...
AAK78622      216 KLIDK-MDKSETEAYNFMIG-KVSSGSMEVLNPEtn----rDFISLWILNS-KTTTKGKFYGGKF-HVKKIVNVKVAFLE 287 Clostridium ac...
AAO36913      217 KMVNK-LPKSESQAYNFLAD-RIEGGTLEIPHPKek----dKFITLEILKS-KTKNKIEKKDNIV-ELTKKIKVKTTLTG 288 Clostridium te...
BAB80355      218 VLVRR-ITAEEGMSYNLLMG-DLKRGTLEVMNPQdp----nTFITLDISNA-KTKTSISYDGENI-TLYKDIKVKCLIGE 289 Clostridium pe...
AAS41664      227 SYINH-LNSHDIAGIRWTDG-NTKRAPLLLK--Fn-----qKIIGHIVLKNpKIDTKHFVKNGKL-RILMNIHFDADIFQ 296 Bacillus cereu...
novoz:BL01752 307 -TTVPIHLDDPKVLSDIERKVAKELKNELQNTIDIVKR-NKTDVLQFGDVVYRTHPEVWkk-mEGEWSNrYFPDTDVDIT 383 Bacillus liche...
BAD64540      275 sGDLSMSA---KDLTKIKELGIQQFEEQMQTLVNRFQQ-RGIDPIGLGDVASSKIRHLN----MEQWHD-TYPSLDIDVN 345 Bacillus claus...
BAB05905      282 -YEKREHVLTDKKFAEIAEEFSRYLEKTCQEMVRRIQKqHQADPMGLGEYTRPLLPVDTs---LEEWRK-KFTASTMSIT 356 Bacillus halod...
AAS39634      288 lEAPRDNLYKMDERKKLNKELSKQLTKEAKKITKKLQK-ANCDAFGIGRHLIAYHPDLWk---KKNWNK-DYAKVKFKPE 362 Bacillus cereu...
BAC12437      284 vDYPPDHLDKQEMINFLENRLSKILTEKADALFKKLAA-NQSDVLGLGRELIAFHPAIWkeikGEN----YYEHILVNPK 358 Oceanobacillus...
BAC14722      276 aEDD-------LADKDIKQMFEEKIERETLQLVQKLQE-QQVDILGISNRLRTRYTNAE----LKNFVNeVYPNINVNVE 343 Oceanobacillus...
AAK78622      288 sQSPITYNK--YMQKQIEQNAEKNIINNCNKIFNKYKE-KNEDIFNVRDVYENIY--------KKGSPD-IIKNTVIDIE 355 Clostridium ac...
AAO36913      289 tQSPMNFTE--EELNIIKARAEYNIKKFSREVFEKYKN-ENIDIFDVADIYNRKYH-------KEDSKN-ILKNTILKVD 357 Clostridium te...
BAB80355      290 sQSRLIVDE--KLLNLLELEEEAVIKQYLELFFESFKE-SDIDIVNVGNLFYRKYPDEVl---EKD----PISITNLKIN 359 Clostridium pe...
AAS41664      297 lIHS-------MPVNDIKEIAEAQVEKEIKTTYRKGIE-RGIDTYQLSHSLYRQNNKLWkk-hKKEGGV-FLQNKELDLN 366 Bacillus cereu...
novoz:BL01752 384 VNAYVRRTGLRN 395 Bacillus licheniformis DSM 13 = ATCC 14580
BAD64540      346 VDLTVIGSGITD 357 Bacillus clausii KSM-K16
BAB05905      357 VDLDIIHDGDFR 368 Bacillus halodurans C-125
AAS39634      363 VEVSILYSGVLK 374 Bacillus cereus ATCC 10987
BAC12437      359 VKVNVRSSGIIL 370 Oceanobacillus iheyensis HTE831
BAC14722      344 VEAVIENNGKLR 355 Oceanobacillus iheyensis HTE831
AAK78622      356 PHVQIERSGKAS 367 Clostridium acetobutylicum ATCC 824
AAO36913      358 ADVKIEGSSNKF 369 Clostridium tetani E88
BAB80355      360 VDVEIDGTTITG 371 Clostridium perfringens str. 13
AAS41664      367 VSINIATNGKSK 378 Bacillus cereus ATCC 10987
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