Conserved Protein Domain Family
Amj

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pfam10997: Amj 
Alternate to MurJ
This bacterial family of proteins has no known function. However, family members include lipid II flippase Amj, which is required for bacterial cell wall synthesis. It transports lipid-linked peptidoglycan precursors from the inner to the outer surface of the cytoplasmic membrane.
Statistics
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PSSM-Id: 431591
Aligned: 43 rows
Threshold Bit Score: 263.636
Created: 24-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
BAF59264        10 LTGFIHLVITLSYAVRLAGLRTGRLLTAVSIFNVINLLAGAANTVQAPLLTSAVEHaikaglvqagtpaasdlavqqQAY 89 
Q97LT7          11 FNFIITFIGTLAYSTRLVGVKTGKIAISFTVFNILTLVSRTAVTFQEPLLTNYAEK------------------------ 66  Clostridium a...
WP_013625168    11 LNFIISLIGTLAYSVRLVGVRTGKIAVSFALFNMLMLVSRIAVTFQVPILTKYVES------------------------ 66  Syntrophobotu...
WP_014096422    11 LNFIISLIGTLAYSVRMVGVRTGKIAVSFAVFNILTLISRIAVTFQVPLLTKYVEG------------------------ 66  Weizmannia co...
jgi:Ccel_2983   11 LTLVIYVVGTLAYSVRIVGVKTGRIAIAFAIFNVFALLSRTANTFQAPLLAKTIEK---------------------SIE 69 
jgi:Clopa_4398  11 LTFVIYIVSTLSYSVRIVGIKTGRIAISFAVFNIFSLIARTANTIQAPLLSKSIEE---------------------SIR 69 
WP_011988921    11 LTFIIYIIGTLAYSARIVGVRTGRIAVSLAVFNVFVLIQRTANTIQAPLLAKTIEN---------------------GIN 69  Clostridium k...
Q63LN3          11 LTFVIHVIATLAYAVRIAGVRTRRIAVSFSLFGIIALVSRTANSFQGPFIAKRVEL---------------------DIS 69  Burkholderia ...
Q2NCA7          11 LAFVINLIGALAYAARIAGVRTGRIAMSFALFNVLLLVSRLSNGFLAPLVAKRVEN---------------------SLT 69  Erythrobacter...
Q1GSL6          12 LTGFINLIGALAYAARIAGVRTRRIAMSFALFNILVLFSRTSNSFLGPFLAKRIET---------------------RLH 70  Sphingopyxis ...
BAF59264        90 REQLSLLAGRIRLVILSSTAGTLAGALFTPAFVRIFARAIHIFEEAGSVPGMFVRLIfSYLPARIKRGgLFVLPRLSSLF 169
Q97LT7          67 NLYSSNLIVIFNSIILVSGAASILGAVLIPTFQRMFSKGVMFFSLEKSIPRLVVHSM-TRRGIYSMKQ-CVVLPSRKSVE 144 Clostridium a...
WP_013625168    67 NPGAGDLLIIFNIIILISGVATVFGAILIPTFQRILYKGVMSFSIDRSLSKLILHSF-SKSGIRYIKE-CVSVPAKENVR 144 Syntrophobotu...
WP_014096422    67 HTETSGLLHIFNLIIIISGVATAVGALLIPTFQRLFYRGVLYFSADRSIPKLVLHSF-SKAGLHYMKD-CVAVPVKENIL 144 Weizmannia co...
jgi:Ccel_2983   70 SGNTGGMLYIFRWILLSATLATIIGAMLLPTFIRVFTKAVESFSVYRSVPRLILHGF-SKSGIEQFKK-SITIPKKENLS 147
jgi:Clopa_4398  70 VGRAGEFLYVFRWILALSTIGAIVGAILMPTFIKLFSKTVNSFSVYKSVPKLLVHSF-SKAGIEQFKK-SISKPKRENIS 147
WP_011988921    70 SGQSAGLIHIFRWVIFSITLATIAGAILMPTFIKIFNKLVISFSVYRSLPRLMMHAF-SKSGIEQFKN-SISIPKRENLS 147 Clostridium k...
Q63LN3          70 RHLGEGLLADFRLFLLSATVASVVGALLIPTFQRYFSRAVHHFQANRSVSRLLLRVF-SRDGVGYIRG-GARLPSPRNVT 147 Burkholderia ...
Q2NCA7          70 GRIATNLESDFRLILLSAFIGVLAGLVMVPTAQRVFVRAIEAVQPRQSLAKTLLRGV-SPGGLRILRT-SLSMPARASVG 147 Erythrobacter...
Q1GSL6          71 DGSGASLFVDMQLVLAAASVATLIGILLVPTGQRMFAAAIGWYQTNRSTTKLAVKAV-SPSGLRTLGR-SLTLPSLAHLK 148 Sphingopyxis ...
BAF59264       170 YWAGRrlLIPRTFLAVNVFVTGLFTTGVLSALYAGALYPDFRSTAAALSAIVNGVAVAIVALVVEPTASLITDEAMQGKR 249
Q97LT7         145 KFNYR--KLPRRIIVYNFISVAALTVGALAPIYAFKIVPNLRATCVTLSSVVNGIAQILMTIFIDPQMSIMTEEVMEKKC 222 Clostridium a...
WP_013625168   145 QISYR--KLPKRIMVYNLAAVALITVGSLAPIYAGFLEPDLRATCITLSPVVNGIATILMTIFIDPQLSMMTDDVIDGKC 222 Syntrophobotu...
WP_014096422   145 QLNFR--KLPVKIIIYNLVTVALLTVGSLAPIYAGSLEPDLRATCITLSSIINGVATILMSIFIDPQLSIMTDDVIDGKC 222 Weizmannia co...
jgi:Ccel_2983  148 QLKSLr-KIPKKIVFLNVITSSISTVGVLASLYAGCLYPEFRTTCSTLSSAINGVATILMFLFIDPYISMMTDDVIKGDC 226
jgi:Clopa_4398 148 QLKSLr-RIPKKIIILNIMACSISTVGVVAALYAGCLNPDLRTTCSNLAPVINGSSTILITIFIDPYTSMLTDDVIRGEC 226
WP_011988921   148 ELKNFn-KTSKKVILLNMISFSVSSISVLSALYAGCLSPDLRTTCSTLSAVINSISTIFMVIFIDPYLSMMTDDVIRGES 226 Clostridium k...
Q63LN3         148 QLATGt-GVSWQVIVLNVVAMAIWTVGVFASLYAGYLKPELRVTCANLSSIINGFATVAMAVIIDPQVSVMTDDVIEGRL 226 Burkholderia ...
Q2NCA7         148 KEKPR--ELTWGILAANGVAQALLVVGVFAAIYAGYLNPEYRVTASQLSAVVNGFATILLFLFIDPHLSVLTDDVVDGKQ 225 Erythrobacter...
Q1GSL6         149 GWKMPr-GISWGVLIANCLAQSLLAVGVVASLYAGYLAPDFRVTASQLSALINGFATILLFAFIDPQLSVMTDDAVEGKV 227 Sphingopyxis ...
BAF59264       250 GEEDVKQMAFYMIISRILGTLLAHALFLPCARLIKYVV 287
Q97LT7         223 SEEDFKNCVLAMVGSKVAGTFAAIFILIPASFAIVFVA 260 Clostridium acetobutylicum
WP_013625168   223 TQEQFRLCVIGLVGSKTIGTFASLLLLLPSSYLIVYVA 260 Syntrophobotulus glycolicus
WP_014096422   223 SEEDFRKVVVAMVGSKTVGTFASLFLLIPSAYAIVFVA 260 Weizmannia coagulans
jgi:Ccel_2983  227 TELDFSRCVIFIVCGLIVGTMLAQILLVPAAMAIASIA 264
jgi:Clopa_4398 227 SELQFSRCIIFIVFGLILGTILAQLLLVPAAMIIESIA 264
WP_011988921   227 TELEFNRCIIFIVGGLIAGSILSQFLLLPASKLIVIIA 264 Clostridium kluyveri
Q63LN3         227 CENHFRRAITTLAGARVLGTLCAQAALVPAALVIVRVA 264 Burkholderia pseudomallei
Q2NCA7         226 SEPSFRRAVAWISLSRLGGTLLAQALFLPAAIAIVWVA 263 Erythrobacter litoralis HTCC2594
Q1GSL6         228 DEAEFRRAITFISLSRLAGTILAQALLLPAAMLIAWVA 265 Sphingopyxis alaskensis
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