Conserved Protein Domain Family
PbpC

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COG4953: PbpC 
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope biogenesis]
Statistics
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PSSM-Id: 443980
Aligned: 190 rows
Threshold Bit Score: 634.949
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_012237040   1 MRAHSqegpgraarwfarlgprarrilRRA--AQIALAL-AVAPwllLa--TLA-ALTPLPPelga--pedHAVSTVLLD 72 
AKU98142       1 MTRFprle---------------rlarKRS--VQALLAC-VLVGw--LawrGFR-WHVGSPAdels--ntgWTQASRVLA 57 
WP_011385342   1 MTRG-----------------------RRA--VWAVLAG-LVLAv---------aVLWPRADlt------aPAATRILLD 39 
WP_014811942   1 MNEASl--------------------kKKIsiQYILLGGsVLLL---Ft-cVLGyMLLPDYRnale--eqrEKAGVVITD 54 
WP_015135884   1 MG---------------------------------------AIAl-sI-------RITPYLIpiraediaqKDQAFTFYD 33 
WP_015183798   1 MRdyirqkvw----------qrlsrshRRF--WKVTLVV-VLLGl-vV-------RSLPYLApirahdlvqDQQAVEFSD 59 
WP_053234888   1 MKAArwr------------------iaRRG--LALAVGL-ALAAwi----------gLPDPLiets-rflhYEDSVEIAD 48 
WP_082175559   1 MRS------------------------RRTr-GAAVLAL-VLLGag-------awFASSLQDgl-----lgYEPSRLVLD 42 
WP_083305423   1 MRNSiniikqki-------wlrrnpkhRRA--IKLFLGL-ALLGi-tV-------RSLPYLApirakdlvqDDLAVEFRD 62 
WP_046320582   1 MLKWPdvvi---------------lrrSRC--VKVVAVM-LLLVv-lI-------RSIPYSIpirakdirqNSVSMEFSD 54 
WP_012237040  73 RHGTVLRELRAGDGARARWLPLSEAGDRIQRALLAAEDKRFVRHPGVDPIAIARAVGQLAAERRVVSGGSTITQQLARTL 152
AKU98142      58 RDGRLLGERPSSEGLYGVQTKLDDVSPRLVSATIASEDKRFFDHDGIDRLAVARAALSDLRHLHVVSGGSTITTQLVKRL 137
WP_011385342  40 RHGAFLAQVGGRDGTLYGYWPVERVPERVAAAIIAIEDRRFGRHGGVDPIALVRAGIERL-RGDGRSGASTIAMQVARMQ 118
WP_014811942  55 RNGQILRILPDANDHLTIWYSIDSIPDIVKTCFIVSEDKRFRYHPGFDPIAIIRAVQSNIARGKTVSGASTITQQVVRLI 134
WP_015135884  34 RHGLRLGTVLSETQEETSVVSLDEISPHFKQAILSAEDKNFYEHGALDLKAIARAIGQAAKYRKIVSGASTVTMQLSRML 113
WP_015183798  60 RNGLPLGTLLTRDQDHTAVLPIEQVSPPFIQAILAAEDGRFYQHGALEMKAIARSILSSIHAGRITSGASTITMQLARML 139
WP_053234888  49 RHGAPLRFARSG-ASDRRWVPLASMSRDLIDAVVAVEDQRFWEHEGVDVRGTFRALVFNFVPGYRWSGASTITQQLVKLV 127
WP_082175559  43 RRGAYLGEVPGTGGELGYWPVPYVLPERIVQATLVTEDRHFYEHPGVYLPSVGRALVQNVRNLRVISGASTLAMQVARMQ 122
WP_083305423  63 RNGLSLGTILSRDQDHTAVVPLDQISPHFLHAILAAEDGEFYHHGALEMRAIMRSLIEAIEAKRIVSGASTITMQLARML 142
WP_046320582  55 RQGLALGTILSQDQSHTAVVPLKEVSPYFIQAIIAAEDKRYYQHGAVDIIAIVRAVMEAIQAREIVSGASTITMQLARML 134
WP_012237040 153 VP----RPRTARGKLGEAALALRIEASLSKREILEQYLNRVAFGPGLRGVEAASRFYFDKPTRDLSLAEAAALASMPRGP 228
AKU98142     138 DHqgrpRPRTVATKLVEMARAQNLESTTSKRALLEAYLNRLDYGRGLAGPEAAAQGYFGVPARDLSLAQAALLAVLPRAP 217
WP_011385342 119 AP----GPRTLPRKLLEAATATLMVARHGRDEVLRHYLRLVPFGNGSHGIAHAARWYLDKPVEDLSWAEIAFLSAIPQAP 194
WP_014811942 135 EP----RPRTIRSKIIEFICALKMEMQLSKDRILELHLNLSPMGRNIYGVGLASRTYFGKDLQSVNVAEAAALAVLPRSP 210
WP_015135884 114 HP----NPWTIPAKMQEIWLSWRLMAGMTHDEILAAYINRLPMGGNIYGVEAAARIYFGVAAEDLSIAQAAVLASLPNNP 189
WP_015183798 140 EP----APRTLSAKLGEIWLSWRLAAGMSKQEILDAYINRLPMGGNIYGVEAASRIYFGMSASELNIAQASILAAIPNNP 215
WP_053234888 128 YG----RPHGVASKGVEIARALALERTFSKDEILEQYLNRLPYGNGIEGVERASQAYFGHSASELTLSEAALLAGIPQAP 203
WP_082175559 123 TP----GGRTAWRKVREAVEALLLVHGHGHEKVLRQYLAIAPYGNRVHGVGRAARLYFDKPVEDLSWAQAAFLAGLPQLP 198
WP_083305423 143 EP----NPRTLPAKFQEIWLSWRLAAGMSKDEILAAYINRLPMGGNIYGLEAAARIYFGMPASELNVAQASLLAGLPNNP 218
WP_046320582 135 EP----SPNTLPHKIREIWLSWRLFAGMNRDEILAAYINRIPMGGNLYGVEAAARTYFGIGASDLSLSQASVLAGLPNDP 210
WP_012237040 229 ALYDPRRGT--GPLERRRNRVLDRMLAAGLAGEAEVARARAEPIALA--P-KGGGLGAPHLVRAV-----LGGAlgpgag 298
AKU98142     218 SALDPHRHR--ERAVVRQRALLTEMNRRGLVSSEDLDRALSEPLLLRdpK-LPRPFVAPHVVLAN-----ARRV------ 283
WP_011385342 195 GRMNPFTREgkARAVRRGHRILAHLHESGLMGAGEFALAERQIEHLAipRhGRRPAEMIHPVLRL-----QRALaas--- 266
WP_014811942 211 SRFNPRWQSgqRMLVAEKDRLLTTMTELGLLSNQSLAVMVGPVIRFV--N-RPLPLEAPHLVDLV-----MARGg----- 277
WP_015135884 190 IYLNPYDYW--ENLKVRQKYVLNRMVMDGYISQDQADQALAENLTLQ--PrHQGIETAPHFLFWL-----TQQLd----- 255
WP_015183798 216 NYLNPYDYW--EPLKRRQVYVLNRMVKDGYITRQQADRAYEEKISLQ--SrQQGILAAPHFLFWV-----ASQLpqs--- 283
WP_053234888 204 SATEPRRHL--PRAMRRRALVLSRLEALGLRSAEEIAAARADEVRVV--PtPPRPWRAARFVDVV-----QRERarg--- 271
WP_082175559 199 GRMNPYTEDglRRARKRSHRILRALHKQGALSREELEQSLQTDLGLV-----PRPRRMPEALHAVlewseLASA------ 267
WP_083305423 219 NYLNPYYYW--DAAKRRQIYVLKRMVEDGYITATQADQAYEEAISLL--PrQQGIIAAPHFLFLV-----ANQLp----- 284
WP_046320582 211 TDLNPYFNW--EGLKQRQKYVLDRMVEDGYITPEKSDRAYRETLRIA--PrEQGIIAAPHFLFWV-----ASQLsk---- 277
WP_012237040 299 lpaggpdaasriveRRATSITLTIDRGLQREIEVLAQQTVRGLSDRDVGAAAVVVIENATGEILAYVGSHDIDDAAGLGH 378
AKU98142     284 --------------PA-GEIRTTLDFALQKDVEAMVRAHVPRLEQRGASTAAVVVVDNATGELLAEVGSAAFGDPKIAGA 348
WP_011385342 267 ------------qaPVPPLVPTTLDLATQRRVHDAASRQMPDWRSRGAEQVAVVVMDRASREVLAWLGSESYFS-PQAGA 333
WP_014811942 278 --------------RQTGNVRTTIDLDLQKSSEQIVRSHKTRLHRMGISQVGLMIASVNPGEVLTLMGSLDY-SEKDLGY 342
WP_015135884 256 -------------aTDHPSVKTSLDKELQEFVTGQVQQTVLNLGKLDATQAAAIALDNKTGEILAYVGSRDYLDQDNAGQ 322
WP_015183798 284 -----------sipHRMSQIRTTLDRPLQQFVEAQVQQIIRTLAPNNVHHAAALVIDNHTGEVLAYIGSPDYFLEAQLGR 352
WP_053234888 272 -----------aliARGGSLRTSLDLALQDRAEQLLEARVRELAPRGVENGAAIVIANASGEVLAYVGAARRGHDAPGGA 340
WP_082175559 268 --------------RAEPISTATLDLEVQSKVASILQRNLNRLDGAGAGNTAALVVDTETGDILAYVGSRDFFNQEHRGA 333
WP_083305423 285 -------------sEHPSQIRTTIDRPLQEFVEAQVQQVVRELAHKNVHHAAAIVIENKSGEVYAYVGSPDYFSEADLGR 351
WP_046320582 278 ------------aeITSPKIQTTLDRTLQQFVETQVRHVVTALGGQNVNHGAAIVINNHTGEVLAYVGSPDYFNWQNLGS 345
WP_012237040 379 NDGVLALRQPGSALKPFVYELAMEQLGFTAATVLPDVELSFpt-anGN-YAPRNYDGRFHGPVRLRDALANSYNVPAVWA 456
AKU98142     349 VDIVRARRQPGSTLKPFVYARAFERG-TSPMEMLADVPTEFgd-arGHaYAPDNFDGTFLGPISAREALAGSLNVPAVRL 426
WP_011385342 334 IDFTAVSRSPGSALKPFIYALALDRGRIAANTILADLPETQ--------WGIDNSDHDYLGPMLPRQALANSRNVPAVSV 405
WP_014811942 343 NNAVVALRSAGSTLKPFLYALSLERGM-QPSEEIPDTFRSYrt-phGD-YLPFNADRRWYGPVSLRSALGNSLNIPAVKT 419
WP_015135884 323 NDGVQALRQPGSTLKPFLYQLAIEQRTIQANTVLADIPTYYaipgeKL-YEPTDYSETFLGPVRVRLALANSLNIPAVRV 401
WP_015183798 353 NDGVQALRQPGSTLKPFVYELALENRIIRPNTVLADVPTRYaipgaKL-YSPADYSETFQGPVRVRVALANSLNIPAVRV 431
WP_053234888 341 LDLLRAPRQPGSTLKPFVYGLLFERGG-TAASVLDDVATPMtg-raGVlYAPRDYDGTERGPVRARVALSSSLNLAALDA 418
WP_082175559 334 IDFVKQRRSPGSTLKPFIYGLALEKGIVTAATELADTPMDVrv-enGRsYVPENINHSFLGPMLLREALGNSRNIPALRV 412
WP_083305423 352 NDGVQALRQPGSTLKPFLYHLALEQRIIRPNTVLADIPTYYaipgaRL-YSPTDYSETFLGPVRIRVALANSLNIPAVRV 430
WP_046320582 346 NDGVQAWRQPGSTLKPFLYQLAIAQGIIRPNTILPDVPTYYpipgaKL-YAPVDYSETFLGPVRVRIALGNSLNIPAVRV 424
WP_012237040 457 AAALGPERVLARLRELGLRSLD-REPSRYGVAIALGDGEVRLVDLANAYATLARGGLYLPVRAVRSfapssspspsspaa 535
AKU98142     427 AADLGATELVSTLRASGL-SLP-LGAERYGLSIALGSGEVTPLELAEAYATLARGGEHVALHERQG-------------- 490
WP_011385342 406 LRQAGLDETHLFLSTLGLHDNT-QAASRFGLVLAVGAMPTTLERLMRAYGAIADDGRLMDLVWWRG-------------- 470
WP_014811942 420 IRELGIKDFYELLGSLQLCNPKiADSEEYGLGLAIGNIEVSLFRLVQAYRVFATQGLFGQLAFIAG-------------- 485
WP_015135884 402 LEDVGVGNFLTRLRDLGFEHLD-QQAEHYGLGLTLGSGEVNLMELANAYRAIANQGNFGEITGELE-------------- 466
WP_015183798 432 LEKVGVPTFLQRLHQLGFAHLT-HPPDYYGLGLTLGSGEVSLWELAHAYLILANQGQVKPLVTQIN-------------- 496
WP_053234888 419 ARRVGPDRVLARLEALGVRDV--PSVEEVGAAAVLGGVDVRAVELAEAYVALARGGTRVPLRCVPGa------------- 483
WP_082175559 413 LERVGVEPTLRFLEKAGVGGIS-YEPDRYGLGLAVGNLHVTLEELAELYLVLAHEGETRSLRRFTG-------------- 477
WP_083305423 431 LEKVGVSNFLLHLHQLGFEHLT-QSPEHYGLGLTLGSGEVSLWELARAYLTLARLGQPTSVVTTLS-------------- 495
WP_046320582 425 LEKVGVGEFLSRLHQLGFTHLD-REPEHYGLGLSLGSGEVSLWELAQAYLTFANRGKFTPLVTTII-------------- 489
WP_012237040 536 ssaspASsgsgap----------------------------------------------aeppaAPPerGA----RVLDA 565
AKU98142     491 -----Q----------------------------------------------------------AAP--TT----RVFDA 501
WP_011385342 471 -----QD---------------------------------------------------------LSP--PG----QVLSA 482
WP_014811942 486 -----ETq-------------------------------------------------------pGPS--AS----RVFSK 499
WP_015135884 467 -----EE---------------------------------------------------------RSP--LTplikGGDQK 482
WP_015183798 497 -----SPlik----------------------------------------------------qeNNP--KS----LIGSA 513
WP_053234888 484 ----------------------------------------------------------------IEE--GT----EVMPA 493
WP_082175559 478 -----EP---------------------------------------------------------MAS--SR----RLMTR 489
WP_083305423 496 -----SPspnrddlsvyrkqgrqgrqerqasggskqlsdhqaskqsplfklpyrnakgeqpnnlKHS--NL----ELSTL 564
WP_046320582 490 -----PEiap----------------------------------------------------pcKQK--CM----QIDTA 506
WP_012237040 566 ARARVIVDILADDRARLASFGEg-NALDLPFPVAAKTGTSKGFRDNIAVGFTPDVTVAVWVGNFDGSPMGGVSGITGAGP 644
AKU98142     502 AAVASISDALSDPLARVRGLRTr-GPFEFNYPVALKTGTSTAYRDAWTAGYTHERTVVVWVGNADGSATRKLTGAVGAGP 580
WP_011385342 483 ATARQITQFLSDPAARLPTFPRl-GASESGLPIAVKTGTSQGYRDAWAVAWTMDTVVGVWTGRARGTTMQAMTGAQSSAR 561
WP_014811942 500 ESSYLVTHILSDPAARLLTFGNp-DYLDFKFPVALKTGTSSKYKDCWIVAYTSRHVIGLWGGNFSGAPGSG-ASAAALGP 577
WP_015135884 483 SSWQLITDMLSDKQARAITFGVd-SALNLPFPAAVKTGTSSNYRDTWTVGFSENYTVAVWVGNFDGSPMNGVSGVMGAAP 561
WP_015183798 514 TTWALITDMLSDPHARAKAFGVd-SVLNLPFPVAVKTGTSSNYRDTWTVGFTTDYTVATWVGNFDGEPMRQVSGVTGAAP 592
WP_053234888 494 DAAAIVRDILADGRARAQAFGSdlHVESEGLEIALKTGTSTGFRDAWAAVFDDRVTVLVWLGDPDGGATRAVSGFEGAAP 573
WP_082175559 490 ESAQLVRHMLSDPLARRPSFPMg-SSLDYPYAVAVKTGTSQGFRDAWALAFSDRLLVAVWVGNHDWRRMNGVGGLLGAAN 568
WP_083305423 565 STWALITDILSDPQARAQGFGVd-SVLNLPFPAAVKTGTSSNFRDTWTVGFTKNYTVATWVGNFNGEPMEQVSGVIGAAP 643
WP_046320582 507 TSWELIVNMLADSHARATAFGVd-SVLNLPFPVAVKTGTSSDYRDTWTVGFTTDYTVATWVGNFDSQPMQNISGVMGAAP 585
WP_012237040 645 LFRDAMLAAARV-RPPRp------FDPPdpEQLAEVEVCALSGMRPTAACP-HRRHELLPRGDVaalsP---CDMHE--- 710
AKU98142     581 LFFDVMKRAMND-VAVRa-----pLSEP--GLLEDAEVCALSGHRAGAACP-DRVHRMFARGHT----PahaCTVHQ--- 644
WP_011385342 562 LAQEILVGLRES-RGENvae--raFPPP--ANYRPVELCARTGLRAAGRCS-QTLVEWFADGHP----Pe-eDDVFQ--- 627
WP_014811942 578 ILKELIVHLYSA-EEPEa------FPRP--EGLEETTICWMSGKIARPDCP-YTTKELVRTSET----PgkcELNHEn-- 641
WP_015135884 562 LWREIMLQLHKD-NEPGa------FPKP--NGMVEKSICALSGKKSTGLCP-AIAQEYFYPEDL--------AQYETdtd 623
WP_015183798 593 LWNRIMLHLHEH-QEPTa------FSPP--SGLVQRSVCALSGMRPTPACP-SVVQEYFYPEDL--------GEYERhpd 654
WP_053234888 574 VAARLFAAAHAR-VASLgatvetsVREDv--ALQHASICAHTGLLAGARCH-AVVTERFTAGTT----PtrtCDAHA--- 642
WP_082175559 569 AVHEIFDAVMPGwRPYRpvl--daFPPP--SGALAMDVCPLSGRLAGPECP-HRKSEWFVPGTA----PaerCPFHA--- 636
WP_083305423 644 LWHRIMLHLHQS-QEPAp------FQAP--PGLVQRPVCALSGLRPTPACP-TVVQEYFYPDDL--------QDYERqsd 705
WP_046320582 586 LWNQIMMYLHRN-KKPDn------FPPP--EGLFELPICSHTGWKPTDDCGsGIVLEYFYPEDI--------KDYDN--- 645
WP_012237040 711 ----TVRIDRRNGLRAG-ACPDAAVE-ERVVERYDAELTAWARAAGRPLA----------PDAASPLCGALAgldgapga 774
AKU98142     645 ----MTVARSAPSNEPAyRCDAGGTV---PVVVLPETFGRWLSERPLGAPgsdphgipwfLASRVPNCva---------- 707
WP_011385342 628 ----LLKVDLRNGLLAApWTPRDYVg-ERTFAAFPPEHAAWGSANALPPPpt------eiSPLDRPQTRAERrvp----- 691
WP_014811942 642 ------------------------dRh-----dLASTYAHWLNRRETQQGsgr----yrlMRSMHDPTNTIIdk------ 682
WP_015135884 624 dfyqEIN--------------------GEIQLTLPAEYNDWLATQTRI-------------------------------- 651
WP_015183798 655 tfyqGVSSGSDG-------------QpSQYRLNLPEEYNEWLAMQPREATlssv---shtLPEgg--------------- 703
WP_053234888 643 ---------------------------EDGALLLPPRYAEWIARVRPADVrvrt-------------------------s 670
WP_082175559 637 ----KVRLDRRNGWRAGpTCPEREVV-TRVMLALPEEYEQWARRQHLDIApl----------reSPLCPNh--------- 692
WP_083305423 706 tfyqITSVGANQ-------------QsPQYIVNLPDEYNEWLARQPQG-------------------------------- 740
WP_046320582 646 ---------------------------LSVTGELPAAYNEWLSQQESP-------------------------------- 666
WP_012237040 775 ppAGAGARVRVAYPPDGARFVLDPSi------nSLQAIRLRAD-VPPGV--PRVRFVLDGRSIE-VGPPFALDWPLVAGA 844
AKU98142     708 -pGSEEPRIVVVEPRDGAVLSAERGar-----saSDALDVAVE-TRGMPagEPLEVLVDGRLAMrLDTAYRARVPVGRGD 780
WP_011385342 692 avQAPDGTLKVIAPRDGLRMARNPEtp-----aeADMLNLRAT-VGRGI--ETVLWLVDGKPWRqAAAHQPVHWPLTAGI 763
WP_014811942 683 fsSARGKGIEIVSPHNHDCFILSPH--------NSRKVLFRAI-PRPAV--DYVTWLLNGTEVArTPAPYEFAWEMSRGT 751
WP_015135884 652 --DVPQSGLQILFPNDGDRLLSFPGd--------pNKLQIQYQ-TINDQ---PVQWFLNEKPWQpSDS-TNPKLNLQPGN 716
WP_015183798 704 klSLSGNHLKIVSPRQGDSFLLYPTes-----gaVQRLEFKLA-ATPTQ---PVEWWLNGEKLAmDSS-NSLFWQLRPGN 773
WP_053234888 671 egSTLVTAPVVVHPRAGARMLADPRr-------gETRIPLRATiAGALA--DDVEWEIDGAVWRe------pTWPLRPGE 735
WP_082175559 693 -pEELEPKVAIREPRGTVRLLYDPDtp-----asASTLRLAAD-VTPST--EPIVWMVDGVPVAeVGYPHEFRWSLQPGQ 763
WP_083305423 741 --NIAPGKLKILSPREGDLYVLYPTesdqdsnsaVQRLEFKVA-GLKSE---SVEWWLNGEKLTtDSS-NSFFWPLGPGD 813
WP_046320582 667 --HLSSGKLRIILPQNNDYFLVTAGh--------dSPLELKVA-GVDNQ---EIQWFINDNKIAtTTS-KSIFWQPEIGD 731
WP_012237040 845 HRLRV-DA---DGaaASEEIAFSVE 865
AKU98142     781 HLLEVrPVdarRGv-LLGRAQISVR 804
WP_011385342 764 HVFQVaTG---DGerMSAPVTISVE 785
WP_014811942 752 YTVLAvTP---YK--NAARIVIHVE 771
WP_015135884 717 WTLQIkQG---D---ADHQVSFTVE 735
WP_015183798 774 WTLEVrSG---D---MSNRVSFQVQ 792
WP_053234888 736 HRFVArA----RGl-RSDEARITVE 755
WP_082175559 764 HVITAaMV---HRpqISQPVTVVVE 785
WP_083305423 814 WTLEVkSG---D---ISDHVTFKVQ 832
WP_046320582 732 FTLKVvTR---EN--MSDRINFQVR 751
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