Conserved Protein Domain Family
MRI

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pfam15325: MRI 
Modulator of retrovirus infection
MRI, or modulator of retrovirus infection, is a family of eukaryotic proteins that regulate the activity of the proteasome in the uncoating of retroviruses.
Statistics
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PSSM-Id: 434635
Aligned: 11 rows
Threshold Bit Score: 97.1748
Created: 22-Aug-2024
Updated: 4-Dec-2024
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q6AYH4        57 MNEAEMVDVALGILI-EGRKQEKPWEQPSLVAPDKLQLSPPCSESPHTSSp----GSSSEEEDSRTDSPAL--GLSPARG 129 Norway rat
XP_003791649  56 LNEAELVDVALGILI-ESHKQEMPWKQLSQGGSDNPERSPTCSTSPHTSS-----GSSNEEENSGKDTPSP--GLGPSLG 127
XP_002687010  55 MNEAEVVDVALGILIeEDRKQEKPLEPPPLAGADKPERSPA-SPAPPSPSprwsrSEDSEEEDRGADGPAP--------G 125
XP_002927666  57 MSEAEMVDVALGILI-EAREQEKPWESPTLAGADKPELSPTCSTLSPSSP-----GSRSEDEDNGKDALPP--GLKPPQG 128
XP_010598738  56 MNEAEVVDAALAVLI-EGRKWEKSLEQKAPAKADKLELSPRSLRSPWSP------GGRSEDKDNGEDSLPP--SLGPSQE 126
XP_007504426  58 MNEAELVDVALGVLV-ECRKQEKPLEHTLLLGTDKDQTAQP--ESPWAS------GSRSDGEEEVDDTPQT--HPSSKQE 126
XP_023609279  58 MSEAELVDVALGVLI-ENRQQEKALEQRPLAGTAEPELSPTCSEGPASPE-------TSEGEDSGEAALPP--GLGRPQG 127
XP_004851280  55 MNEAELVDVALGILI-EGRTQEKPWEELAVAGAEKTELCPTGSRSPHTSS-----GGNSDEEDSGNHGLRPeaGPSPSQR 128
1_pfamImport   1 MNEAEMVDVALGILL-EGHAWEKPQEELAVGGTEKAELCPAGPWSPHTSS-----GGNSEEEDSENDRPTL--GLSSSQR 72 
2_pfamImport   1 MNETELVDVALGILI-EDGKQEKAGELPSLLGADKPEGSPS--PSPHTSS-----GSSSDEEEGEDDAPVP--GLSPPNT 70 
XP_003951193  56 MNEAEIVDVALGILI-ESRKQEKACEQPALAGADNPEHSPPCSMSPHTSS-----GSSSEEEDSGKQALAP--GLSPSQR 127
Q6AYH4       130 PEASNSPCSRSPEEgkeEEDELKYVREIFFS 160 Norway rat
XP_003791649 128 PGVSDSACSGSPEK---DEDELKYVREIFFS 155
XP_002687010 126 PAGSDTACSRSLEE---DQDELKYVREIFFS 153
XP_002927666 129 CTGSDPACSRSPEEd-eDEDVLKYVREIFFS 158
XP_010598738 127 LGGSDSTHSESQKE---EEDALKYVREIFFS 154
XP_007504426 127 CSASGYKKGSGDEE---NEDALKYVREIFFS 154
XP_023609279 128 PAGLEPACSSSPEE---DEDAFKYVREIFFS 155
XP_004851280 129 PETFTSACSRSPEQq--EEDVFKYVREIFFS 157
1_pfamImport  73 PGMPTSACNRDPEEeeeAEDVFKYVREIFFS 103
2_pfamImport  71 AGGRRP-EEEEKEE---EEDVLKYVREIFFS 97 
XP_003951193 128 PGGSSSACSRSPEEe-eEEDVLKYVREIFFS 157
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