1T0F


Conserved Protein Domain Family
Tn7_TnsA-like_N
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pfam08722: Tn7_TnsA-like_N 
TnsA-like endonuclease N terminal
The Tn7 transposase is composed of proteins TnsA and TnsB. DNA breakage at the 5' end of the transposon is carried out by TnsA, and breakage and joining at the 3' end is carried out by TnsB. The N terminal domain of TnsA is catalytic. This domain is also found in Bacteriophage T4 gp4-like head completion protein whose nuclease activity is required for packaging. This domain contains the catalytic triad of one basic and two acidic residues that form a restriction endonuclease-like active site and conserved between TnsA with gp4 proteins.
Links
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Statistics
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PSSM-Id: 462579
Aligned: 96 rows
Threshold Bit Score: 39.5091
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
1T0F_A             77 SSVLDIREQFpLlpsdTRQI-AIDSGiKHpvirgvdQ----------VMSTDFLVDCKDGPFEqFAIQVKPAAALQ-D-- 142 
LANL:DM80_3964     75 DDILEYYMQPcEl---RLELvDDSTG-EI-------Hki--------tHIPDFLTISHDGF---ALEEWKSEAKLArlse 132 
jgi:Rpic_4577      77 NNVLEFYTQPcQl---KLELiDEATG-KT-------Hss--------tHVPDFLSIRNDGF---MLEEWKSDVKLErlae 134 
jgi:Bcen1808_0159 107 STTREFYCQPpQv---GIPT-KIWRT-SR-------RgkvteythtvPYTPDIFRLTPYGP---LVEEWKNEEKLIalak 171 
jgi:Bphyt_3873    108 GTTREYYCQPpQv---RLVV-ETERK-RS-------DgtvtyyqaptPYTPDILRLTPYGI---YIDEWKTERDLEclae 172 
Q815N0             24 RSVLEYYDQPpSf---KISY-RIKE--KN-------Rah--------fYTADFFVISDDWI---GWEEWKTEDDIIklsi 79   Bacillus ...
O85715             74 PKVLEFYDQPpPf---KIQY-KNQAG-RN-------Igh--------yHTPDFFVLRHDGA---CWEEWKTVKELEflaq 130  Microchae...
WP_000277808       47 PKVINFCEQP-L----VMTA-CIN-G-KS-------V----------TSIVDMWVKYEDGNEE--FIEIKYSTDLIkQrv 99   Bacillus
Q3EZ34             37 SDIAVFCEQP-L----KIAY-EFE-G-KN-------T----------HTIFDMWVQERSGKEY--FVEVKYSQEMRkGnk 89   Bacillus ...
WP_012080882       67 PRIVSFKEQP-A----TLTY-FLN-G-KT-------Y----------KHFPDLFVVGNGRAA---FIEVKSHTDpd---- 114  Janthinob...

1T0F_A            143 --Ert--------lEKLELERRYWQQKQIPWFIFTD 168 
LANL:DM80_3964    133 kypyrys-kssdgqwyapqIEKQLADLGIRYRVCSG 167 
jgi:Rpic_4577     135 rfpyryv-rssdglwrspqIESQLAELGIRYRIFSD 169 
jgi:Bcen1808_0159 172 kypfrfyksesdatwhcpeREEYFKALGITFCLRSS 207 
jgi:Bphyt_3873    173 kyprrff-rdddgtwrcpeRERHFATIGMTFCLRSG 207 
Q815N0             80 eyperyq-ldengiwrcppAEKHAENYGLSFRVKIS 114  Bacillus cereus ATCC 14579
O85715            131 kypgryq-ktasghwrcppGEAHASQFGLKYCVRTD 165  Microchaete diplosiphon
WP_000277808      100 -iN-----------QIFT-QKYWCAENGFQHRVRTE 122  Bacillus
Q3EZ34             90 kyNrt--------mKQLEIQRAWCEENKKEYRIMTE 117  Bacillus thuringiensis serovar israelensis ATCC 35646
WP_012080882      115 -lCea--------iERGDAIRPVLLMQGFDYFVVTD 141  Janthinobacterium sp. Marseille
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