Conserved Protein Domain Family
ZnMc_MMP_like_3

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cd04327: ZnMc_MMP_like_3 
Zinc-dependent metalloprotease; MMP_like sub-family 3. A group of bacterial and fungal metalloproteinase domains similar to matrix metalloproteinases and astacin.
Statistics
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PSSM-Id: 239819
Aligned: 14 rows
Threshold Bit Score: 237.663
Created: 3-Aug-2006
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
active site
Feature 1:active site [active site]
Evidence:
  • Comment:consensus motif: HEXXHXUGUXH U= bulky hydrophobic
  • Comment:coordinates zinc, contains catalytic Glu
  • Citation:PMID 8253063
  • Citation:PMID 8756323
  • Comment:Based on similarity to sequences with known structures.

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                                                                                       
ZP_00054902  94 KYWGKNGVTLTVGFldn--------------------ppADLRARILAHMNAWGTya------nTHFAESnv----dpQV 143 Magnetospirillum...
YP_284047    76 KKWPAGTTLRCLFLdg----------------------sTTMKKKVRAYAHQWEKqa------nIKLKFVtka---paEI 124 Dechloromonas ar...
ZP_01127152  73 KKWVNGTKLRYYFFksgp-----------------fsgeDTQKALVREGFDVWKAvg-----igIGFEEVadi--gesEV 128 Nitrococcus mobi...
BAE61712     63 KFWKPGSELRIAFMsg----------------------tPWQHDQVKKFAPIWTQya------nLKFKFVdydkssppDI 114 Aspergillus oryzae
ABA72839     20 HFWTPGQTLRIAFLng----------------------dQPFKDAVKSAASEWLSyi------nLNFDFVege---sgDI 68  Pseudomonas fluo...
XP_762648    99 KLWPECTSTIRYTFlssp-----------------hggtKEQEQKVRDSIQEWTYya------nVDLKEVkda--sdaDV 153 Ustilago maydis 521
CAK16913     47 KLWRPGRVLKVAFLgs---------------------pdEFLKSEIFRTASQWLLrsganlslaLTWDNDsqa---qiKV 102 Pseudomonas ento...
XP_389273    18 ENPKNGHQLTAGDAvpga------------------qspLALAIPVGSMWRNGRKlrnn--ysgVKFVFVdsg---daEI 74  Gibberella zeae ...
BAD56877     58 KYWRSGGVHLGVRFldt--------------------tdRALQDRILAHMNAWSPga------nIGFHRStap---daEI 108 Nocardia farcini...
AAF19103     33 RMWANATVLHYCFLggdtdasvvpmpgtgrprrgswagtEEQRDVVRDCFREWRDlg-----igLGLEEVrdr--seaEL 105 Streptomyces coe...
Feature 1                                                          ##  #     #                  
ZP_00054902 144 RISRtagdGYWSYLGTDvlt---igaDKATMNLDSftmnt-rdseFYRVVRHETGHTLGFPHEHRRKEIVd--------- 210 Magnetospirillum...
YP_284047   125 RISFyadaGSWSAVGRDalnqayfplHQPTMNYGWlrddt-pddeYSRVVLHEFGHALGCIHEHQTPTFNr--------- 194 Dechloromonas ar...
ZP_01127152 129 RIGFlsgdGAWSYVGRDvidi--pgqSERTMNFGWdltq---dprGVDTPVHEIGHTLGFPHEHQNPFAGi--------- 194 Nitrococcus mobi...
BAE61712    115 LINFdpsrGSNSYLGTDsagv--arhGRHSMNLGWinekt-senaRRSTILHEFGHALGAAHEHSSPRAEi--------- 182 Aspergillus oryzae
ABA72839     69 RISSep-gIYWSMIGTHall----ieDGPTMRLSPdlqa---pafFAANVMHEFGHALGAEHEHLHPESNi--------- 131 Pseudomonas fluo...
XP_762648   154 RVRFdpqdGSWSYVGLDvtk---vdaQAPTMNLAWvqktgalsqnEQATILHEFGHTLGLLHEHQSPAHGakatinvdaa 230 Ustilago maydis 521
CAK16913    103 RTGRtl-pRNESCAGTDal-----amPAETMNLNVepg----datFEHVVLHEFGHALGAEHEHQHPDASi--------- 163 Pseudomonas ento...
XP_389273    75 RVNVndnrRSWSYVGTEnla---ipaNKPTMNFGWltdtt-pdmeFSRVIVHEFGHALGCIHEHQSPAGGi--------- 141 Gibberella zeae ...
BAD56877    109 RIARtpgdGYWSYLGTDvlq---ipaDEPTMNLDSfgldt-dereYTRVVRHETGHTLGFPHEHLRRDVVh--------- 175 Nocardia farcini...
AAF19103    106 RIGFqpgdGSWSAVGKDalg---vglNDRTMNFGWdlt----apgERATALHQIGHALGMLHEHQSPFAGi--------- 169 Streptomyces coe...
Feature 1                                                                   #                   
ZP_00054902 211 --------QIDFEKAVAyfmasqgwtrekvisq----vltplqdadlnatadADRTSIMCYWLPGSIMKngepv----vg 274 Magnetospirillum...
YP_284047   195 --------KWDVKAVMKyfqgppnywtedsikh----nvlqkysptgiaatvFDPKSIMLYSFDAALFAdglgp---tne 259 Dechloromonas ar...
ZP_01127152 195 --------IWDEEAVYNyfggppnnwsretthh----nvlkkllpgavegseWDPDSIMHYKFQAGLIEkpeeyqegltp 262 Nitrococcus mobi...
BAE61712    183 --------NWNKEAVYArysgppnkwdkakidh----nvlrkipdkytkateFDPDSIMLYAFPGSLTMdgkgt----er 246 Aspergillus oryzae
ABA72839    132 --------PWNKAAVYAahwvkenadeddyarrsvderyfnlldasdfdyspYDPKSIMHYAVRQDWTHgdfki----dl 199 Pseudomonas fluo...
XP_762648   231 lvmystgqPWDDQQVRDqvinayknsd----------------iskisnyseVDPRSIMHCPQPKELTGfdrdv----pc 290 Ustilago maydis 521
CAK16913    164 --------PWNVEEVVRvanaeqgwtrqqvme-----emiarrtdiglvktpYDPASVMHYPVPQAFTLgdwei----gl 226 Pseudomonas ento...
XP_389273   142 --------PWDKEKAYAyyssgnnsdretvdr-----nifdyysftisrfsdVDKSSIMMYEIQKSITTngyft----vs 204 Gibberella zeae ...
BAD56877    176 --------RIDPAKAIRyfrdrvgwseattra-----qvltpleevalittpTDTQSIMCYQLPGSIMRdgrpv----pg 238 Nocardia farcini...
AAF19103    170 --------LWDDEAVYAelagppnhwsrertfh----nilrkldgdeangpvWDPQSIMEYPFSSGLILepehyrsglrp 237 Streptomyces coe...
Feature 1                        
ZP_00054902 275 gvDIDKVDADFAASIYP 291 Magnetospirillum magnetotacticum MS-1
YP_284047   260 nsKCSSDDIKMIGTMYP 276 Dechloromonas aromatica RCB
ZP_01127152 263 qpGLSDSDIEEVRRLYP 279 Nitrococcus mobilis Nb-231
BAE61712    247 khFLSARDKEFMRFIYP 263 Aspergillus oryzae
ABA72839    200 nlELSEKDKTFMSKAYP 216 Pseudomonas fluorescens PfO-1
XP_762648   291 ntGLSDLDKAYMVLQYP 307 Ustilago maydis 521
CAK16913    227 nsGLSEKDLAFMRLAYP 243 Pseudomonas entomophila L48
XP_389273   205 ntKLSDTDKTFIATVYP 221 Gibberella zeae PH-1
BAD56877    239 glDINDRDRGFVHVLYP 255 Nocardia farcinica IFM 10152
AAF19103    238 pgTLSAADKEFALRWYP 254 Streptomyces coelicolor

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