Conserved Protein Domain Family
MHT1

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COG2040: MHT1 
Homocysteine/selenocysteine methylase (S-methylmethionine-dependent) [Amino acid transport and metabolism]
Statistics
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PSSM-Id: 441643
Aligned: 196 rows
Threshold Bit Score: 221.223
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_084208600   7 RNP---LsAITAQQPFLIVDGALATELERAGFDLNDSLWSARVLADE--PQAIVDVHRAYFEAGADVATTASYQATLEGL 81 
WP_041766425   1 --------MKSQFRLPIILDGGMGRELKRIGAPFQQPEWSAQALIES--PHFISEVHKSFIEAGAEVITTNTYALVPFHI 70 
WP_013047226   1 ---------------MIILDGGLGRQLAAVGAPFRQPEWSALALMEA--PQYVRDVHDSFIAAGADVITTNSYAIVPFHI 63 
WP_081441415   2 VNRn----WKLLNGELLLLDGATGTELNRRGLDTGLPMWSANALTTDtgLNVLRQIHLDYLQAGADILTANTFRTHRRAL 77 
WP_014951074   1 --------MKEGMHDILILDGGMGRELKKTGAPFKQPEWSALALMQT--PELVSDVHKRFLEAGACVITTNAYALVPFHI 70 
WP_013695471   1 -------mDKNFFNTTRILDGGMGQELLNRGVKPEGTLWGATALLHKkyHKIIVDTHLDFIKAGAEVIVTNSFGSRKRRM 73 
WP_014560387   4 LSEfniFsFSKKIKRPLVLDGAMGSFLEKMGLTETDNAWSAKANIKY--PDKVLKIHRSYIEAGADVITTNTFRTNPYSL 81 
WP_013857202   1 ------------MSKLTLLDGGMGRELKRIGAPFSQPLWSAQALIES--PQHVRLAHQGFIDSGADIITVNSYACVPFHL 66 
WP_005504773   1 --------------MFVLLDGGMGRELQRIGAPFSQPLWSAQALIEA--PEFVYQAHQNFIDAGCDVITVNSYACVPFHL 64 
WP_117314880   1 ------------MNQITLLDGGMGRELKRSGAPFDHPYWSAQALWEA--PEAVEQAHCRFIEAGAQIITVNSYACVPFHL 66 
WP_084208600  82 MARSLseTQASALIQRSVTLAAQARSE--YlaahperlDCPPLVAASVGPYGayladgSEYRGGYALDRAGLRDFHRARL 159
WP_041766425  71 GEKRFn-EQGADLIKLAARLARECVKE-----------NSAVLVAGCIPPVL------GSYRPDLF-SVEKAKPVLELLI 131
WP_013047226  64 GQDRFd-ELAPQLLTLSGTLAQAAAEA--A--------DRQVKVAASIPPMF------GSYEPDKF-DPQTGQQMMQLFQ 125
WP_081441415  78 ASKV---HAARELTMRAVATAQEAIAE--F--------GQAAQVAGSVSPLE------DCYRPDLVPPDDMCRAEHSERI 138
WP_014951074  71 GENTFr-EQAFTLAQNAAELARGAVNAlkSd------gDNKRFVAGSVPPAF------GSYRPDLF-DATRVADILTPLI 136
WP_013695471  74 IENGVl-SKFKSANKTAGILAKRAVQE--S--------KKKILIAGSLPPQH------FTYFSDMGTDLNVIKEYFYEQA 136
WP_014560387  82 GQVGI--KNFERYVKKAISLAFEAKEN--L----------PVLIAGSNAPAE------DCYQVQRTITKKQLELNHRCHI 141
WP_013857202  67 GESLYq-TDGARLANLAAQIAAEVAQQ--S--------ERPILVAGSMPPAM------GSYRPDLF-QAEVARAISLTLY 128
WP_005504773  65 GEQRYk-EQGFTLAERAAQIARRAADD--S--------EQEVKVAGCIPPAL------GSYRPDLF-NARQAKPILQTLV 126
WP_117314880  67 GQAMYa-ERGAQLATEAAKIAQAAAAKy-P--------TSPVKIAGCLPPPM------GSYRPDLF-DAPAALTIYQELL 129
WP_084208600 160 ATLLDAKPDVLAVETLPCAEEAQAVCDLLrDD-FpTARAWIAFSARNAt------ELSDGTPIREAVRAIDDCEQVVAIG 232
WP_041766425 132 KNQEAD-VDIWLAETISSIAEAAMIKART-VV-T-NKPTWIAFTIKDEitt--epALRSGESVYDAVSQIAG-QNVSAIL 204
WP_013047226 126 RHLAPS-ADIFLAETLGSVIEAKIFLESF-VD-C-AADLWLSVTLEDVkpvpgapRLRSGEPLSALLDVIAS-KRLDGLL 200
WP_081441415 139 QHLVDAGVDLLLIETMSSIREAVIAAKLA-TI-T-GLPTLVSFVCDGEg------RILSGEPVAVAAELLLP-LGVKALG 208
WP_014951074 137 KAQEPY-VDVWLIETASSVEEAEAVVSLI-KQyS-SLPLWLSFSVSNRetsnepvTLRSGEPLSEIAPILSE---VQSVL 210
WP_013695471 137 KILNPY-VDFFYLDVMSSFKECEIAIKAI-AP-L-KKDFLVGIHIREGe------KLPSGEDFVSVVKKLSK-LNPLGVV 205
WP_014560387 142 DSLIDNGCHFILNETQGHFDEIKIISKHC-EK-Y-EIPFVMSLYFDENl------CLLSGEKVSDVINFLN-DTNVLSLG 211
WP_013857202 129 QAQDPY-VDVWLAETIASLEELSMIQSVF-AS-S-TKPCYYALTLKDDsn---iaQLRSGQSVSEAAEQIYS-AGGAGIF 200
WP_005504773 127 EAQVGY-CDFWLAETISSIEEFQTIHGVL-RT-T-NQPAYYAFSLMDTevd--qpRLRSGESVIDAIHAVCT-AGVDGVL 199
WP_117314880 130 AAQDPW-CDLFIVETLASLEELKVVQIAA-RA-T-DKPVHYAFSLDDNlnd--gaRLRSGQSVASAVALVCADRHAAGIA 203
WP_084208600 233 VNCTALEHIESLVREIRG----------ET--DKNIVIYPNSGEVYDPVTKTWSAacavsvdsdgdgSDHDhdLAGWTPR 300
WP_041766425 205 FNCSGVEVMETALITAKQall-----dkEIedQVQLGVYANNFPPIGELHQ---Anqdhgv-sgirdDVPPekYHEFGLS 275
WP_013047226 201 FNCSQPEVMHDAVTCVSEfrarqpsrpaGM--GLQIGVYANAFPLMNDDYE--HAnstlh---qirhDITPqnYAKYAVQ 273
WP_081441415 209 VNCGPAHTLAKPLVELRRi--------cGP--DFPLIAYGNIGYADEAQGWINTD------------AESPesYLHHAET 266
WP_014951074 211 FNCSQPEEMEDAISITRSl---------DT--SINIGAYANSFSERKRTHA---Analls---eirdDITParYVEYVKT 273
WP_013695471 206 VACVSVEHLEPLIKKILKi-------------KIPFGFKINAFQHIPAGWKPDSNnpnvk--lgkrkDLTPatFYSISKK 270
WP_014560387 212 FNCISDKILIKLINQISm--------------PANWGFYLNCFSTSEKQSKVC--------------SISVaeYLAIVQE 263
WP_013857202 201 FNCSIPEVMADAIQQVKMvle-----grAQ--KIEIGVYANSFTPIKSDHA---Anqtv----qamrEFSAedYLAFAKQ 266
WP_005504773 200 FNCSQPEVMLDAIGVSKGiid-----deGK--AISLGAYANGFTVIHQDHE---Andal----ttmrDLPAdeYAAFVRA 265
WP_117314880 204 LNCSIPEVMAHALQEAYSilt-----reQR--KLTLGVYANNFRPIPNDYA---Ansqs----qpmrELSPedYLEFVKQ 269
WP_084208600 301 WLAAGATAIGGCCRTGPDDIRALADLRKA 329
WP_041766425 276 WINAGASIIGGCCGVSPAHIKKLAElk-- 302
WP_013047226 274 WAAAGADIIGGCCGISPEHIEILAAALKN 302
WP_081441415 267 W---PAQILGGCCGTTPAHIRRLRVRSND 292
WP_014951074 274 WVAAGATIIGGCCGIGPEHIKAISDVFGQ 302
WP_013695471 271 IHKAGATILGGCCEITPKHIARLKKi--- 296
WP_014560387 264 VIHFNPSFIGACCGSNPEFIKAIKGFLDG 292
WP_013857202 267 WYALGATVIGGCCGITPRHIQALYEWRRS 295
WP_005504773 266 WLDAGSNIVGGCCAIFPEHIAYLDALRKR 294
WP_117314880 270 WVATGASLVGGCCGIGPEHIQALSQWQAT 298
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