Conserved Protein Domain Family
IolD

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COG3962: IolD 
TPP-dependent trihydroxycyclohexane-1,2-dione (THcHDO) dehydratase, myo-inositol metabolism [Carbohydrate transport and metabolism]
Statistics
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PSSM-Id: 443162
Aligned: 140 rows
Threshold Bit Score: 917.209
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_108718863   2 TSATVRLTTGQALVRFLAHQWTERDGERRRLFAGVFGIFGHGNVAGLGQGLLQahveavkagyageehGPDELPYLMARN 81 
WP_041936237   1 MGKTIRLTMAQAVAHFLKVQMTIVDGKKVPIFGGVWAIFGHGNVAGIGEALYQ---------------VREELTTYRAHN 65 
WP_044551101   1 MSKTIRLTMAQALTRFLSRQMTEIDGKKMPIFGGVWAIFGHGNVAGMGEALYQ---------------VRDELPTFRAHN 65 
WP_014129470   1 MTDTIRLTMAQAVARFLAAQMTEIEGERVPLFGGVWAIFGHGNVAGMGEALYG---------------VRESLPTYRAHN 65 
WP_055046830   2 TNKTIRLTMAQALARFMTRQKTVIDGKTVPIFGGVFAIFGHGNVAGFGEALYQ---------------VREELPTYRAQN 66 
WP_061978149   2 TSKTIRLTVAQALVRFMMAQKTVIDGEVLPIFAGCWAIFGHGNVAGMGEALHG---------------VKDEFPTYRAHN 66 
WP_064329556   1 MAKTIRLTMAQAVAHFLKAQMTVESGKKVPIFAGVWGIFGHGNVAGMGEALYQ---------------VREDLPTLRAHN 65 
WP_083269225  34 PMAKIRLTMAQALVKALAAQKTVIDGQTLPLFAGVWAIFGHGNVAGLGEALHG---------------ARDGLPTYRAHN 98 
WP_075800674   1 MTSTIRLTMSQALTRFLANQFTEVDGRELPLFAGVWAIFGHGNVAALGEALYQ---------------ERERLPVLRGHS 65 
WP_099509660   1 -MSTIRLTMAQAVARFLTAQKTEIDGKILPLFGGVWAIFGHGNVAGMGEALHG---------------VRETLPTFRAHN 64 
WP_108718863  82 EQGMVHAAVAYARTTNRLQTFACTASIGPGSTNMVTGAALATIDRIPVLLLPSDVFATRLPDPVLQQLEHPLGPDVTVND 161
WP_041936237  66 EQGMAHAAIAYAKANFRTRFMACTSSIGPGALNMVTAAGVAHVNRIPVLFLPGDVFANRAPDPVLQQIEDFGDGTVSAND 145
WP_044551101  66 EQAMAHAAIAYAKANFRRRFMAATSSIGPGALNMVTAAALAHVNRLPVLFLPGDVFANRIPDPVLQQAEDFSDGTATVND 145
WP_014129470  66 EQGMAHAAIAFAKASFRRRMMACTSSIGPGATNMITAAALAHVNRLPVLFLPGDVFASRRPDPVLQQVEDFADGTVSAND 145
WP_055046830  67 EQGMAHAAIAFAKASFRRRFMAATSSIGPGATNMVTAAALAHVNRLPVLLLPGDVFANRAPDPVLQQVESFQDGTVSAND 146
WP_061978149  67 EQGMAHAAIAFAKASFRRRFMACTTSIGPGALNLVTAAGVAHVNRLPVLFLPGDVFANRLPDPVLQQVEDFGDGTVSASD 146
WP_064329556  66 EQGMAHAAVAFAKASFRQRFMACTTSIGPGALNMITAAGVAHVNRLPVLFLPGDVFANRIPDPVLQQIENFGDGTVSVND 145
WP_083269225  99 EQAMAHAAIAFAKASRRRRMMAVTSSIGPGATNMVTAAAVAHVNRLPLLLLPGDVFAGRRPDPVLQQIEDFGDGTVSAND 178
WP_075800674  66 EQGMAHAAIAFAKASFRRRMMAVTTSIGPGALNLATACAVAHVNRLPLLLLPGDVFASRRPDPVLQQVEDFGDATVSAND 145
WP_099509660  65 EQGMAHAAIAFAKASRRRRMMACTTSIGPGATNMVTAAAVAHVNRLPVLLLPGDVFANRRPDPVLQQIESFSDGTVSAND 144
WP_108718863 162 AFRPVSRYFDRIWRPEMLLASAPQAMRVLTDPAETGAVTLALPQDVQAEAYDWPREFFRDRTWHVARPVPEPAALARAVA 241
WP_041936237 146 AFRSVSRYFDRITRPEQIITALKRAMQVLTDPLDCGPVTLSLCQDVQAEAYDYPESLFAEKVWTTRRPQPDADELANAIA 225
WP_044551101 146 CFRPVSRYFDRITRPEQIIPALSRAMQVLTDPADCGPVTLSLCQDVQAEAYDYPESFFAERVWHQRRPRPDRHELAAAVT 225
WP_014129470 146 CFRPVSRYFDRITRPEQIMPALRRALQVLTDPAECGPVTLALCQDTQAEAFDYPVSFFAETVHVQRRVRPDANELARAVA 225
WP_055046830 147 VFRPVSRYFDRITRPEQIIPALNRAMQVLTDPAECGPVTLSLCQDVQAEAYDYPEAFFDERVWTPRRPQPDTNELEAAVA 226
WP_061978149 147 CFRPVSKYFDRIQRPEQLIPALGRAMQVLTDPVDCGPVTLSLCQDVQAEAYDFPAALFAEKVWNTRRPRPDVDELTHAVS 226
WP_064329556 146 AFRCVSRYFDRITRPEQIIPALKRTMQVLTDPVDCGPVTLSLCQDVQAEAYDYPASLFEEKVWTHRRPRPDSDELAAAIA 225
WP_083269225 179 CFKPVSRYFDRLTRPEQLIPAFERAMAVLTDPAECGPVTLALCQDVQAEAFDYPEAFFAERIWTPRRQRPDEAELAEAAV 258
WP_075800674 146 CFRPISRFYDRITRPEQIIPALERAMVVLTDPAECGPVTLSLCQDVQAEAYDYPAAFFERRVWHGRRPRPCEAEAARAVA 225
WP_099509660 145 CFRPVSRYFDRITRPEQIIPALQRAMTVLTDPAECGPVTLALCQDTQAEAYDYPESFFADRIWTPRRIRPDEAELADAAD 224
WP_108718863 242 TIRSARRPLLVAGGGVVYSQASDALRAFAEATGIPVADTQAGKGALPWDHPLAVGGVGATGNDAANALAASADVVIGVGT 321
WP_041936237 226 LIKASQKPVIVAGGGVLYSQATKELAAFAEAHGIPVVVSQAGKSAINETHPLALGSVGVTGTSAANAIAEETDLVIAVGT 305
WP_044551101 226 ALKGAKKPLVIAGGGVLYSQASDALAKFVEGAGIPVCETQGGKSSLPDDHPLNMAAVGVTGTSAANRLAEEADVVLAIGT 305
WP_014129470 226 AIEGAQKPVLIAGGGVLYSGAGDVLARFAEAHDIPVMETQAGKSALPHSHKLNMGSVGVTGTSAANGLAEQADVVLAVGT 305
WP_055046830 227 ALSAARQPVIIAGGGVLYSEAASTLQNFAEKHGIPVMETNAGKSSLPHDHPLNMGSVGVTGSSASNLLAEQADLVLAVGS 306
WP_061978149 227 LIRAAKKPMIIAGGGVLYSEATRELLSFAETHGVPVAVTQAGKSAIDETHDLALGAVGVTGTSAANALAADADLVLAVGT 306
WP_064329556 226 TLRKAEKPLIIAGGGVLYSQATAELKAFAGMHGIPVAVTQAGKSALPDDHPLCMGSIGVTGTSAANAFAEEADVILAVGT 305
WP_083269225 259 LLKAAEKPFVVVGGGVLYGEAEAELARFCEAHGLPAAETQAGKSALPFDHPLNLGAIGVTGTGAANAMAEEADVVLAIGT 338
WP_075800674 226 LLRGARKPLIVAGGGVLYAGAAEDLAGFAERHGIPVAETQAGKSSLPFGHPLAMGAIGVTGTSAANTLAEEADVIIAAGT 305
WP_099509660 225 LIRNAKKPFVVAGGGVLYSGAEKVLADFAQKHGLSVGETQAGKSSLPHDNQANLGAIGVTGTGAANALAEEADVVIAVGT 304
WP_108718863 322 RWTDFTTASHTVFAhEDVRFVNLNVAAFDAAKHAADMVVTDARTGLTALADALAGYRPEDGYGDEIAERVAAWQGVTDAC 401
WP_041936237 306 RCQDFTTGSWALFKnDSLKMIGLNIAAYDAVKHDSHPLVADAREGLKALSAGLSGWKAPAALAEKAAAEKKIWMEAAARA 385
WP_044551101 306 RLQDFTTGSWALFKnSGKTIIGLNVQPFDAGKHRALPLVADAAEGIAELGAALKGWKAPAGWTDNAAKGKKAWQADAAKV 385
WP_014129470 306 RLADFTTGSWALFKnPDAKFVALNVAAVDAGKHGAMPLLADARVGLAALSEGLGDWRAPEGWRGEADERKLEWLGEADAA 385
WP_055046830 307 RLQDFTTGSWALFKaDGVRIVGLNAQLFDAGKHRALPLVADARAGLEALDAKLGSWKSPDVWLATARDAKAKWLVSAKAV 386
WP_061978149 307 RLQDFTTGSWALFRaEELAIVGLNVAPYDAVKHGGVPLVADAKVGLELLSEALGDWKADGTQAQRAHDERVRWFEGAGKA 386
WP_064329556 306 RMQDFTTGSWSLFKnDAVTMIGLNTAAFDAAKHDSQPLVADAREGLTLLSEALGGWKAPAAVEAAAKSRKDEWMAAANRA 385
WP_083269225 339 RLQDFTTGSWSLFSnPACRIIGLNVQAFDAGKQRARPLVCDARAGLAELDAALAGHRAPETWTAQAKSARTDWLTTAAHY 418
WP_075800674 306 RLQDFTTGSRSLFRgEGRRILGLNIQPFDASKHHAVPLVADLATGLAALEEGLPDYAAPPAWRERAEALKRDWVAAADRA 385
WP_099509660 305 RLQDFTTGSWALFKnPDRRIVGLNVQTFDAAKHNALPLVADARVGLEELSRALGAWKAPDAWTAKARQEKTRWFDKAARY 384
WP_108718863 402 YDGTfeeagqgeggddavdetgaprreRTAMAQTQVFGVLNELM-RPTDVLINAAGSMPGDLQCLWRASSPEQYHLEYGY 480
WP_041936237 386 MATTn----------------------AALPSDAQVIGAVARTIgGENTTVLCAAGGLPGELHKLWPATAPGSYHMEYGF 443
WP_044551101 386 TASTn----------------------AAFPSDAQVIGGVQRAM-GSGVTLLHAAGGLPGELHKLWQAGTPGSYHAEYGF 442
WP_014129470 386 TAATn----------------------APLPSDAQVIGATQRTM-G-EAIVVCAAGGLPGELHKLWKAESPGRYHLEYGF 441
WP_055046830 387 TDPTn-----------------------ALPSDAQVIGAVHRAR-GSSATLVCASGGLPGELHKLWPAGAPGSYHMEYGY 442
WP_061978149 387 LAATn----------------------AELPSDAQVIGAVARARgTADTIVVCAAGGLPGELEKLWAPTAPGGYHMEYGF 444
WP_064329556 386 TAATn----------------------AALPSDAQVIGAVQRAIgGDNSVLVCAAGGLPGELHKLWRANRPGGYHMEYGF 443
WP_083269225 419 TAAGn----------------------AALPSDAQVLGAVQRWS-EPSDVVVCAAGGLPGELHKLWQAGAPGGYHMEYGY 475
WP_075800674 386 MAPTd---------------------dAALPSDAQVIGAVGRAL-DWNATVVCAAGGLPGELHKLWRPTAPGRYHLEYGF 443
WP_099509660 385 TDPTn----------------------AELPSDAQVIGAVQRTS-QPTDVVVCAAGGLPGELHKHWKASTALGYHMEYGY 441
WP_108718863 481 SCMGYEIPAALGVKLARPDATVVAIVGDGTYQMAPQEIATIVSEGLAVVLVLLDNGGYASIGALSESRGSQRFGTRFRTR 560
WP_041936237 444 SCMGYEIAGGLGAKMARPERDVVVMVGDGSYMMMNSELATSVMLGLKLNIIVLDNRGYGCINRLQMGTGGANFNNLLKDS 523
WP_044551101 443 STMGYEIAGGLGTKMAKPGEEVVVMIGDGSYLMLNSEIATSVMLGLKLIIVLLDNRGYGCINRLQMATGGANFNNLLKDS 522
WP_014129470 442 STMGYEIAGGVGVKLARPADEVVVMVGDGSYMMGNSELSTAVMMGLRLTVVLLDNRGFGCINRLQMATGGENFNNLFEDV 521
WP_055046830 443 STMGYEIAGGLGVKLAKPHDDVIVMLGDGSYMMMNSEIATSVMLGKKLTIVVLDNRGFGCINRLQMATGGANFNNLLKDT 522
WP_061978149 445 SCMGYEIAGGLGTKMARPDKDVIVMVGDGSYMMLNSELATSVMLGQKITVVLLDNRGYGCINRLQMECGGANFNNLLEDC 524
WP_064329556 444 SCMGYEIAGGLGVKLARPEADVVVMVGDGSYMMMNSELSTSIMLGQKLTIVVLDNRGYGCINRLQMATGGANFNNLLKDS 523
WP_083269225 476 SCMGYEIAGGLGVKMADPAREVVVMLGDGSYLMMNSEIATSVMLGLKLTIVVLDNRGFGCINRLQGATGGAPFNNLLADS 555
WP_075800674 444 SCMGYEIAGGLGVKLARPEEEVVVMVGDGSYLMLNSELASAVMLGLRFTVVLLDNRGYGCINRLQAGCGGAAFNNLLADA 523
WP_099509660 442 SCMGYEIAGGLGVKMADPSREVIVMVGDGSYLMMNSELASSVMLDKKLIIVLLDNRGYGCINRLQRATGGESFNNLLQHT 521
WP_108718863 561 NAgtraldGAPTPVDLAANAASFGVRVIRVTTPEELRAAYLEAAAADETTIVHAVTDLYGPNPPGSAWWDVPVAETSTLP 640
WP_041936237 524 YH------EVMPEIDFRAHAESMGAIAVKVASIAELEQALADSRKNDRTSVFVIDTDPLITTEAGGHWWDVAVPEVSSRS 597
WP_044551101 523 RH------EILPDIDFAAHAASMGAIAEKVPSIAGLENALQKAKTNDRTTVLVIDTDPLVSTDAGGHWWDVAVPEVSARP 596
WP_014129470 522 RR------EAMPDIDFAGHARAMGAHAQKVAGIAELEAALAQARARGGVNVVVIDTDPLVTTEAGGHWWDVAVPEVSERA 595
WP_055046830 523 FH------ETLPEIDFAAHAASMGAWVRKAASIAELESALAEADKVERTTVLVIDTDPLISTDAGGHWWDVAVPEVSVRP 596
WP_061978149 525 RQ------EVVPEIDFVAHARAMGAVAEKAGSIAELEAALERTRGNDRSTVILIDTHPLITTEAGGHWWDVAVPEVSTRA 598
WP_064329556 524 MI------ETMPDIDFRAHAESMGAVAVKVSSIADLETAIERSKGNDRTSVIVIDTDPLITTKDGGHWWDVAVPEVSARD 597
WP_083269225 556 RH------ETLPAIDFAAHAASLGAVSRKVASLAELDEALRESRAHDRTSVVVIDTDPMISTDAGGHWWDVAVPEISTRA 629
WP_075800674 524 RH------DTLPEIDFAAHARSLGAEARHVRSLAELERAVREARNASRATVIVIDTDPAIITREGGHWWDVAVPEVSQRP 597
WP_099509660 522 NH------VTLPEIDFAAHAASLGAQAIKVKGIGELEDALKKARSAERSTVIVIDTDPLASTDAGGHWWDVAVPEVSVRE 595
WP_108718863 641 STQRARAEYTAARAAQRTYL 660
WP_041936237 598 EVNRAHEAYVKARAAQRVG- 616
WP_044551101 597 QVIAARKAYDEKRQMQSVGD 616
WP_014129470 596 DVRAKRAEYAERIKGQRIG- 614
WP_055046830 597 EVNAARREYEAALKGQRL-- 614
WP_061978149 599 EIGPARAKYETNRAFQRAIN 618
WP_064329556 598 EVNTAREAYVKALEAQRIG- 616
WP_083269225 630 EVAQARQRYDDALKARP--- 646
WP_075800674 598 EVAAARARYDAARQGQRFd- 616
WP_099509660 596 PVKTARKNYETALAAQRVGD 615
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