3ALC,1CLD,1D66,1PYI,1HWT


Conserved Protein Domain Family
GAL4

?
cd00067: GAL4 
Click on image for an interactive view with Cn3D
GAL4-like Zn2Cys6 binuclear cluster DNA-binding domain; found in transcription regulators like GAL4. Domain consists of two helices organized around a Zn(2)Cys(6 )motif; Binds to sequences containing 2 DNA half sites comprised of 3-5 C/G combinations
Statistics
?
PSSM-Id: 238023
Aligned: 118 rows
Threshold Bit Score: 31.865
Created: 1-Nov-2000
Updated: 2-Oct-2020
Structure
?
Program:
Drawing:
Aligned Rows:
 
Zn2+ bindingDNA binding
Conserved site includes 6 residues -Click on image for an interactive view with Cn3D
Feature 1:Zn2+ binding site [ion binding site]
Evidence:
  • Comment:2 zinc ions are bound
  • Citation:PMID 9886294
  • Structure:1HWTC

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
Feature 1          #  #      #                #  #        #   
3ALC_A      9 RQNHSCDPCRKGKRRCDApenrneanengwvSCSNCKRWN--KDCTFN 54  Emericella nidulans
1HWT_C      5 RIPLSCTICRKRKVKCDKlr----------pHCQQCTKTGvaHLCHYM 42  baker's yeast
CAD11346   15 KSRKGCETCKRRHIRCDEsf----------pQCRNCTKHK--IRCPYN 50  Neurospora crassa
6323257    39 KSKTGCDNCKRRRVKCDEgk----------pFCKKCTNMK--LDCVYS 74  baker's yeast
Q9P326     50 RSRTGCYTCRLRRKKCDEgs----------pMCTACKHLG--LCCEYK 85  Neurospora crassa
T41663     16 RSRYGCLICRSMRKKCDEvh----------pQCGRCLKAG--KQCIWK 51  fission yeast
T49729     86 KSRRGCFTCKRRRVKCSEkl----------pECDNCTRIG--LICEYP 121 Neurospora crassa
1708888   154 YSRNGCSECKRRRMKCDEtk----------pTCWQCARLN--RQCVYV 189 baker's yeast
1169197   313 RSRMGCLTCRQRKKRCCEtr----------pRCTECTRLR--LNCTWP 348 Candida albicans
136747     12 YSKHGCITCKIRKKRCSEdk----------pVCRDCRRLS--FPCIYI 47  baker's yeast

| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap