Conserved Protein Domain Family
ComC_Streptocco

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NF033214: ComC_Streptocco 
competence-stimulating peptide ComC
Members of this family are ComC, a secreted peptide that stimulates competence for natural transformation in Streptococcus. ComC peptides fall within the broader family of PF03047, a homology family of pheromone/bacteriocin precursors that is also restricted to Streptococcus. The PF03047 HMM runs only a few residues past the GlyGly precursor peptide cleavage site, and thus does not distinguish ComC from other pheromone precursors, such as BlpC.
Statistics
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PSSM-Id: 468000
Aligned: 21 rows
Threshold Bit Score: 46.9581
Created: 11-Oct-2024
Updated: 3-Dec-2024
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_004248788  1 MKNTVKLEQFVALKEKDLQKIKGGEMRKMNEksfNFFNIFRRR 43  Streptococcus
WP_004238992  1 MKNTVNLDKFVELKEKDLQNIQGGEIRQTHN---IFFNFFKRR 40  Streptococcus
WP_000799699  1 MKNTVKLEQFVDLKEKDLQKIQGGEMRRIDK---IFINFLKRR 40  Streptococcus mitis
WP_000798830  1 MKNTEKLEQFKKVTEAELQEIRGGEIRKENN---FLFYFFKRK 40  Streptococcus
WP_007518199  1 MKNTVKLEQFKEVTEAELQEIRGGDKRLPYFl--KHLFSNRTK 41  Streptococcus oralis
WP_000799681  1 MKNTVKLEQFKEVTETELQEIWGGEWRIPELi--RNLIFPKRK 41  Streptococcus mitis
WP_001066643  1 MNNTVKLEQFKEVTETELQEILGGDLRISETi--RNLIFPRKK 41  Streptococcus mitis
WP_000799679  1 MKNTVKLEQFKEVTEAELQKIQGGDWRISETi--RNLIFPRRK 41  Streptococcus
WP_006154841  1 MEKTVKLEQFKKLTEKELQEIQGGDWRFLGSi--RELIFPKKN 41  Streptococcus infantis
WP_006146051  1 MKKTVKLEQFKELTEKELQEIQGGDRRITSFf--ANL-FQKRK 40  Streptococcus peroris
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