283783146   2 PMVDIDWLKDHVE--V--PEgltyEQLAKDLVRVGLEEEEIHTSQ--VTGpIVVGYVVDATPepQKNGKTINWCHVDVgd 75 
42561125    1 MIITRNWLKKYLNldN--ISn---DQINMALNSLGFEVDSVYDLNslNSE-LILGYVEQSKQ--IPDTH-LKLNQVNI-- 69 
148377337   1 MIISLREINKYMp--EinLD----SSIEKSINNLGYEVESIKQFSd-VKG-IKFGYVLDVFK--NENSKNLNIVSIKT-- 68 
291320005   1 MIISLREINKYMp--EinLD----SSIEKSINNLGYEVESIKQFSd-VKG-IKFGYVLDVFK--NENSKNLNVVSIKT-- 68 
294155575   1 MIFSLKKLNTYLp--GikLN----KDVEQVINKLGFEVESIKKFSt-IEG-VVFGLIKELYK--NPNSDLLTVATVETk- 69 
54020338    1 MLFSLRRLKKLANleA--FSd---QKVIDSLINLGFEVDQITKLNe-ISG-IKFGQILEIRK--NPEADNLWICKVQF-- 69 
71894322    1 ---MNKYLPEIKl--D--------QSVTKALESLGFEVEFFEKFSs-SKG-LLFAKVLNVFD--NPNSTKLQVVELDT-- 61 
71893622    1 MLFSLRRLKKLANl-Ea-FSd---QKVIDSLINLGFEVDQITK-LneISG-IKFGQILEIRK--NPEADNLWICKVQF-- 69 
72080613    1 MLFSLRRLKKLANleA--FSd---QKVIDSLINLGFEVDQITKLNe-ISG-IKFGQILEIRK--NPEADNLWICKVQF-- 69 
83319488    1 MIITRNWLKKYLNldN--ISn---DQINVALNSLGFEVDNVYDLNslNSE-LVLGYVEQSKQ--IPDTH-LKLNKVNI-- 69 

283783146  76 kyndvdenG--KKvpRGIVCGAPNMAAGEKVVVTLPGAVLPGdFKIEPRK--TYGHISDGMCASERELGL--------G- 142
42561125   70 --------Gt-Ks--LQIVCGASNVDANQFVVIAPINATIANgLTLTSKK--IQNYESQGMICALNEIGI--------Dl 128
148377337  69 --------N--TGi-ITIQTTATNVKKNHWIVAFVEGASK---GEIVFGKkeMAGVVSNGMLASYSELGY---------- 124
291320005  69 --------N--RGi-ITIQTTATNVKKNHWIVAFVEGASK---GEIVFGKkeMAGVVSNGMLASYSELGY---------- 124
294155575  70 -------hG--N---LTIQTTDNVLKVDDLVVCFIEGSKMGD-IVFKTKN--LKNIPSQGMFASYEELGF--------Dg 126
54020338   70 --------A--DKi-REIQTAAKNVIENKQVLAFIPGSKSGN-TTFLAKK--LRGHISEGMLISAVELGFnkhllnseL- 134
71894322   62 --------Kl-GE--LTIQTTNKVLSKGDLTICYPVGSSYQG-KEFQEVT--MQGYKSQGMLASFSEIGY---------- 117
71893622   70 --------A--Dk-iREIQTAAKNVIENKQVLAFIPGSKSGN-TTFLAKK--LRGHISEGMLISAVELGF--------N- 126
72080613   70 --------A--DKi-REIQTTAKNVIENKQVLAFIPGSKSGN-TTFLAKK--LRGHISEGMLISAAELGFnkhllnseL- 134
83319488   70 --------GtkS---LQIVCGASNVDVNQFVIVAPINATIANgLTLTSKK--IQNYESQGMICALNEIGI--------Nq 128

283783146 143 ----DSh---------nG--IILLReygfsK-AEydelkP---GDDVMELLHLNKPILEINITPDRGYAFSYRGVAREYH 203
42561125  129 svinKEdqlkiynvsdkNldLKKYI------------------GSDVKQIIGLDDYLFEIDLTLNRSDCLASFQILKELA 190
148377337 125 ----DSsllp---fdpnG--VILLD-------DSs----In-eDLDPIKYFNLDDYIIDITTPANRAETNSYYVLAMELA 183
291320005 125 ----DSsllp---fdpnG--VILLD-------DSs----In-eDLDPIKYFNLDDYIIDITTPANRAETNSYYVLAMELA 183
294155575 127 klfgDL-----------GehILRLD-----KnFAs----I---NDDPMQVLQLDDYILDVSTTANRNDANSYYVMAKELA 183
54020338  135 ----DQ-----------G--VLVFDp-------------IfdlESNPLKVLELDDLILDIKLLWNRPDGNSYLVLANELA 184
71894322  118 ----DNsll------tdKdqILVLPknfasL------------NDDASEKLELNDYIFELSITTNRNEINSYYFLAKELA 175
71893622  127 ----KHllns---eldqG--VLVFDp-------------IfdlESNPLKVLELDDLILDIKLLWNRPDGNSYLVLANELA 184
72080613  135 ----DQ-----------G--VLVFDp-------------IfdlESNPLKVLELDDLILDIKLLWNRPDGNSYLVLANELA 184
83319488  129 svinKEdqlkiynvfdkNldLKKYL------------------GKDVKQIIGLDDYLFEIDLTLNRSDCLASFQILKELA 190

283783146 204 HSTGAVYTDPVsklneQVSQIND-EghktsdIDV-SI-----E------DT-Npih---------gvpGCDRYYARAVHG 260
42561125  191 NYF-------D--------------------LKIkNLdnnfsDfk--knNL-D---------------LKIDLANQVKDQ 225
148377337 184 AYYKTKFVWPN----------------------L---------------LPkDnyrfrsnikvskneaTELTFFEARLKN 226
291320005 184 AYYKTKFVWPN----------------------L---------------LPkDnyrfrsnikvskneaTELTFFEARLKN 226
294155575 184 AYYETEFVFNE-----KNHKGSLfSd-------I-AIdrgmsN-------------------------EITMFQAYCDKE 225
54020338  185 AFFKTDFSLI------NKEISGKfY------SEL-KI------------IN-K---------------TDSKIFALEIQK 223
71894322  176 AYYNTKFSCEF--------------------LDA-KL-----K------QSfE---------------SSFKFEGNFLDK 208
71893622  185 AFFKTDFSLIN------KEISGKfY------SEL-KI------------IN-K---------------TDSKIFALEIQK 223
72080613  185 AFFKTDFSLI------NKEITGKfY------SEL-KI------------IN-K---------------TDSKIFALEIQK 223
83319488  191 NYF-------D----------------------L-EIknydnKfndfkeNDlD---------------LKITISKKIEEQ 225

283783146 261 ------FDsTCASPRWMQRR--LTRAGMRS-IS-----------LAVDITN-YVMLDLGQPLHAY--DLDKI-------E 310
42561125  226 ------IKtISYSYFELNNK--NDKLDSKDeIFlklnqinssnhSITNLSL-ISTLSTAQTHILI--DLDKL-------K 287
148377337 227 ------NKtSLKDILFLAKH------GINAkGL-----------YAIDLTN-IALLVAGVPCHVY--DKNKI-------G 273
291320005 227 ------NKtSLKDILFLAKH------GINAkGL-----------YAIDLTN-IALLVAGAPCHVY--DKNKI-------G 273
294155575 226 ------FDlNIFDKMLLAKH------NIDTsLG-----------WAVNLTN-LVLIITGAPCHVY--DKNKI-------- 271
54020338  224 ------LPkLALVDIFL-----LLKSEVKI-GN-----------LAQNFSN-FILIYTGQPSYCL--QLEKHqqkveliE 277
71894322  209 nysftlLEaKGKVSTSFEEKllLAKHKIDSkFN-----------PAVNLTN-LVLINLGIPIHVY--DKAKL-------K 267
71893622  224 ------LPkLALVDIFL-----LLKSEVKI-GN-----------LAQNFSN-FILIYTGQPSYCL--QLEKH-------- 269
72080613  224 ------LPkLALVDIFL-----LLKSEVKI-DN-----------LAQNFAN-FILIYTGQPCYCL--QLEKNqqkveliE 277
83319488  226 ------IKtISYSNFVLNNH-----------LN-----------KLDSIDDiFLKLNQISSTNNLinDLSLL-------- 269

283783146 311 G-----PIV-VRRA--HEGEHLTTLD-GK--DHEL----HVe---------DLVICDsprgnhgSR--VLGLAGVMGGMY 364
42561125  288 S----------------SNLKLEFINhDN----------KE----------LLCLTN--------NnkLVNIIGLDTQNE 323
148377337 274 K-----SLScSKFSgeLE-----ILG-GK--KVSV----SD----------VLAIKD--------EtgVISLASVMGCEN 318
291320005 274 K-----SLScSKFSgeLE-----ILG-GK--KVSV----SD----------VLAIKD--------EtgVISLASVMGCEN 318
294155575 272 ------GLKiTSEL--Y-SGKLKLLG-NK--DVDV----EN----------VLIIRD--------EnkPISVASVMGLET 317
54020338  278 Q-----KVK-IKYE----PDTIS--------SYHFlnqeKK----------PLLIPE-------F--------------S 308
71894322  268 StkfsvGLY---------NGKVNLLG-NK--QVEV----SD----------ALAVFN--------GdkVVSLAATMGLEE 313
71893622  270 ------------------QQKVELIE-QKv-KIKY----EP-----------------------D---TISSYHFLNQEK 299
72080613  278 Q-----KVK-IKYEpdA-ISSYHFLDqEK----------K-----------PLLIPE-------F--------------S 308
83319488  270 ----------STLS---TAQTHILIDlDKlkSFNL-----KlelinhndkeLLCLTS--------DnqIVNIIGLQTESK 323

283783146 365 GEVTSE---------TKNILIEAAHFDPVSIARTARRHKIPSEASRRFERGVDTQLQPAAAQMAANLLEQF-----GG-- 428
42561125  324 FNVDNN---------SKNVLNIMLNIEPNLMRKQQKLLNISNTYLQRYIKPINPNLFNLANQTFSNLLNDY------Ql- 387
148377337 319 SAVDEN---------TKEVVFEVGLFDPLLVRHGAREIKMDTASSIQAGRALNSQIVFNGISFLKYKSALD------Cqs 383
291320005 319 SAVDEN---------TKEVVFEVGLFDPLLVRHGAREIKMDTASSIQAGRALNSQIVFNGISFLKYKSALD------Gqs 383
294155575 318 TKVDEK---------TKEFIFEIGVFDPTLIRHSVKQIKLLSNSANQASRTITNEILELGILFLRKYLNDN--------- 379
54020338  309 DQIIME---------NNSFFLIMPKFNLLKVKQIKQFLKKNSLKLTQLGKNYNYGTTFIALSFLNFFLEDQ------Kid 373
71894322  314 SKVDLQ---------TSEFIFEMASFPSKLIRNNAKEIKMNSNASNLASKTITKYQVKLAHKFLFNYLKDL------K-- 376
71893622  300 KPLLIPefsdqiimeNNSFFLIMPKFNLLKVKQIKQFLKKNSLKLTQLGKNYNYGTTFIALSFLNFFLEDQkidfsW--- 376
72080613  309 DQIIME---------NNSFFLIMPKFNLLKVKQIKQFLKKNSLKLTQLGKNYNYGTTFIALSFLNFFLEDQ------Kid 373
83319488  324 FSIDNN---------SKNVLNIMVNIEPNLMRKQQKLLNTSNINLQRYIKPINPNLFDLANLNLTSLLNSY------Nl- 387

283783146 429 -AKP--STSPCDVNNTqs---rnVIVFKANEVQRVAG-LDVDL----NRISD---ILTDIGCS------VAGGgngsF-- 486
42561125  388 iNKAyeVKILKQTFKNk-----qSLEIKLNEINDLLG-TNLTI----KQIKS---LFKHLDFK------ITNKdd-lL-- 445
148377337 384 vSQI--VNIPKVKKg-------kSVIQSRKKLSIYAN-CNIKDlsifDDVEK---TLKKIGFS--------------Mdk 436
291320005 384 vSQI--VNIPKVKKg-------kSVIQSRKKLSIYAN-CNIKDlsifDDVET---TLKKIGFS--------------Mdk 436
294155575 380 ------KISISNLLGIpkigpkkMIKFDKEKLSVYSDqNTSSL----KKFIPaieKLKKLGFS--------------Fdl 435
54020338  374 fSWPinFDKSLISKKT-------FLDLNYNELKEILG-LELSQ----EDISKtnlILEKIGYN--------------Fdn 427
71894322  377 ------LSNVVNDFELdk---kvEINFDEEKLQRYSN--GLPS----SEFIKafdKLKLLEFE--------------Fen 427
71893622  377 --PIn-FDKSLISKKT-------FLDLNYNELKEILG-LELSQ----EDISKtnlILEKIGYN------FDNTs------ 429
72080613  374 fSWPinFDKSLISKKT-------FLDLNYNELKEILG-LELSQ----EDISKtnlILEKIGYN--------------Fdn 427
83319488  388 vNKAykVKVLKQTYKNk-----tEFEIKISEINDLLG-TNLTI----DQIKS---LFKKLDFKitnkndL-------L-- 445

283783146 487 ---SVLPPTWRPDLNEPCDLVEEIARLVGYDEIPVKV--PavpVTG-RT-GLTAQQQTR-RAIAYELA-ETGFVESLSYP 557
42561125  446 ---DFQIDQNRIDITSKNDLCEEVARLYSYDKIDEIPlsFt--SFK----KAKNLNLKLeNKLTNYLI-GLGFNNTKTYS 515
148377337 437 --nRVIAPTYRSDIQHYEDVIEEYFRFYGYSNFKPEA--P----------KLELYKVAHsVDNKNILQ-SLGYNEIRTFS 501
291320005 437 --nRVIAPTYRSDIQHYEDVIEEYFRFYGYNNFKPEA--P----------KLESYKVAHsVDNKNILQ-SLGYNEIRTFS 501
294155575 436 evnEVYVPIYRYDINYFEDIIEEIFRFYSYDNFEPVQl------------SNTSFKIHKrSTIKHELQ-ANGYNEILTYS 502
54020338  428 --tSFSPPFYRVDIEFFADYAADFLRFYGLEKLKDCKl------------EQVKSKIPN-PDLEPVKLkTLGYYETNSFL 492
71894322  428 --qKIKVPLYRYDVSIFEDIIEELFRFYNYDNFKEIPyiQ----------IPGELKADN-KNFKEKLK-ALGYSEARTFT 493
71893622  430 ----FSPPFYRVDIEFFADYAADFLRFYGLEKLKDCKleQv--KAK-IPnPDFEPVKLK----------TLGYYETNSFL 492
72080613  428 --tSFSPPFYRVDIEFFADYAADFLRFYGLEKLKDCKl------------EQVKAKIPN-PDFEPVKLkTLGYYETNSFL 492
83319488  446 ---TFNIDPNRIDISSKNDLCEEVARLYSYDNIQEVAl-----SFTsFK-KPKNLNLKLeNKLTNYLI-GLGFNNTKTYS 515

283783146 558 FVGEEDIK--A-FRQnvdevaevSV---R--I--ANPLAGDRPWLRRSVLMTLAGTVRRNLH-RGLTDISMYELGHVYFs 626
42561125  516 LTSLNEAKywNlFN---------IS---Ef-InlVSPLSNLRQTYRTNLSKSLIDVAIFNHS-INNKELKLFEIADIYDl 581
148377337 502 LISSE-----MnILnpfn--fesTV---K--L--MTFVSKEREEVRNSIIPSLLESAEFNLK-RKINNVSLFEHGM---- 562
291320005 502 LISSE-----MnILnpfn--fesTV---K--L--MTFVSKEREEVRNSIIPSLLESAEFNLK-RKINNVSLFEHGM---- 562
294155575 503 LLSKQKNF----LN---------VFdfqEe-LalETFVSKEREVIRNSIIPSMLEAVEYNQK-RKINKINFFEVGMINN- 566
54020338  493 LIS-KEED----FN---------PLelkSqdL--LTFPSQEHTKIRYSLAWQLAKITKYNQK-RKITEINLYEKGSIAG- 554
71894322  494 LVNEKDSK----FD---------PLdlsDa-IklETFVSKEREFVRNSLAISLAEAVNNNKK-KKINNVNLFEVGMV--- 555
71893622  493 LISKEENF--N-PLEl------kSQ---D--L--LTFPSQEHTKIRYSLAWQLAKITKYNQK-RKITEISLYEKGSI--- 552
72080613  493 LIS-KKED----FN---------PLelkSqdL--LTFPSQEHTKIRYSLAWQLAKITKYNQK-RKITEINLYEKGSIAG- 554
83319488  516 LTTQIDAKhwNlFN---------ISdfiN--L--LSPLSNLRQTYRTSLSKSLIDTAIYNHSiN-NKELKLFEIADIYN- 580