Conserved Protein Domain Family
DUF2389

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pfam09493: DUF2389 
Tryptophan-rich protein (DUF2389)
Members of this family are small hypothetical proteins of 60 to 100 residues from Cyanobacteria and some Proteobacteria. Prochlorococcus marinus strains have two members, other species one only. Interestingly, of the eight most conserved residues, four are aromatic and three are invariant tryptophans. It appears all species that encode this protein can synthesize tryptophan de novo.
Statistics
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PSSM-Id: 462816
Aligned: 52 rows
Threshold Bit Score: 51.1369
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
jgi:MICPUN_60610      147 TNWTAHRRTK-GWRHFECIGkspadKANGKPRASVHLAATCDRDvTVWVDVKELKDRHLWSAGWK 210
tigr:AHA_1107          12 SKWTKESRHElTERFYLVVAcq-rdA--QGQLQQVVMQDINTLL-EQEMDWHELEDPAHWHMGWN 72 
ABM03662               22 SKWTKITVLN-KEKHFLVSEve-fnE--DKKIIRCVMQAVINHA-EYEINWRSLKEGKEWLIGWK 81 
Q07Y30                 14 SKWTKVNVVQ-KLKHFTVAKve-ydE--QQNVVECFIRAEMNAE-EFSIDWRDLKDPQLWKIGWQ 73  Shewanella frigidimar...
Q87FW8                 12 SKWTATSPKN-KEKHFVVTEme-ldE--DGNVVQCVIEAVMSKR-EQEMNWQDLKDPELWRQGWK 71  Vibrio parahaemolyticus
Q6LKS1                 13 SKWTAVNPVK-KEKHFLVTEve--fE--KNEVIHCLIEAVIFKR-TQAIDWNDLKNKDSWLLGWK 71  Photobacterium profundum
CAV18303               12 SKWTAVSPVK-KEKHFMITEve--fE--EGEVIRCLIEAVMTKR-EEDINWRDLTDKDHWLPGWK 70 
WP_014110634           12 SKWTAVTPVN-KEKHFIISDle-fdE--EGIVVACCIEPVMSKR-PTPINWLDLKDDNRWLQGWK 71  Glaciecola nitratired...
Q12I96                 12 SKWTAVAPVN-KEKHFMVTEie-fdE--EGVVILCSIEAVISKR-SAPIDWHDLQDDTRWVHGWK 71  Shewanella denitrific...
instpast:LEPBI_II0214  18 SKWTSVNILD-REKHFIVTKvh-wqEGSTDTLDQVTIEAILTKK-SKMIPWENLKDNAQWLPGWK 79 
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