Conserved Protein Domain Family
DisA

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COG1624: DisA 
c-di-AMP synthetase, contains DisA_N domain [Signal transduction mechanisms]
Statistics
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PSSM-Id: 441231
Aligned: 394 rows
Threshold Bit Score: 149.85
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_084792829   1 MVDISLVAVLLYQVYK-LMKGSMAMRVFLGFVFFYGFYFLVK---SLQMELLSNILSYVMSGGILALIILFQNEIRKFLL 76 
AKM84741      38 LIDILLVFGLLWWLYR-RLRRSDLIKIFPKILFLLLLALLAR---TLGLWALFIVTSSLTVVALLAIAALYAPEIKGVLE 113
AOR39443       8 FIQIVFLAGLLLFLYRkFIKNTSSEKFVKGLLILVCAWAVSEimmRVDLKIIGMFLKSIVTLVSLSLIVIFQPELRRFLG 87 
NP_972512     18 VFDVLLLAFLMYKAYQ-ILLKTQAIQLIKGAMSILVIYAVAM---IFNLKTLLWLLNTLGPGLVIGVAIVFQPELRKIFL 93 
WP_015905127  16 LFDILFNSYVLFRLYV-LFRGTNVIRVLIVISLLWFVQQTAL---AMGLIITSWAIQGIITIGAFVIIIVFRNEISSVLQ 91 
WP_013254238  17 LLDISILAFLLYQLYM-ILAETRAIQLIKGALFLGILYAVAF---FLKLETMQWIMNSLATVIVIIIAIVFQPELRNIFT 92 
WP_041177423  20 GLDIVLVAVLFYIIYM-LMYNTRAYSIAVGFIILFFITLIAK---VFGLSTLSWIFDQFFQVGLIAIVVIFQAEIKHALR 95 
WP_014271102  16 VLEIGVLAWFFYRFYE-AIAQTKAQQIIRVFVTLFSAYALSY---ILKLEVLLWFFKNITIPTAIFICIVYQPELRRSFT 91 
WP_024268673  17 ILDILILALIFYRAYT-IFLQTRAVQLVRGTLLIILLYAFAY---ILRLETVLWLLNFLAPSLVIGIAIIFQPELRKIFT 92 
WP_010882270  18 LLDVALLSFLLYKTYE-ILVKTQAVQLVKGAFSILVLYALVF---VLKLETLLWILNATAPGVAISITIVFQPELRKIFL 93 
WP_084792829  77 MV--AKSMsdFw-HRnSnpifrsfyknqsNGKSGTSPSLNAVVEAAREMSFSNTGALIVLSKNSELRMIASSGDLLDAKV 153
AKM84741     114 TT--GPK---LpsFGdQp----------rASVGDVQTMIRAVAEAAAVLSRGHKPALFVIKKDKSLTRLIDNGTRMHSLV 178
AOR39443      88 FL--GQVD--F--VT-Kifn-------qnNKTEQKIDVVKELVESAKYLSKSHTGALIVFQSDL-RNTYSDVGTKLNADL 152
NP_972512     94 KI--GQSN--W--LR-T-------------GKHSNHSHIDSVVTAAEILSDKRRGMLVVFMRRNNLKDIIDTGTKLNAGL 153
WP_015905127  92 TK--SFKS--F--FW-G------------IPRHQFQTPVSIIVESVYELSRRKLGALIVLPMKQGLESCVQGGISWQGKL 152
WP_013254238  93 RI--GRGE--W--FR-S-------------ASRARPEQLDTVINAVEILAARRRGALIVFPRKVGIKNLIDQGTKLNADL 152
WP_041177423  96 IL--GGKA--F--LK-K-------------SFRYDEDQIQKILSATFNLSYKGYGALIVFQRNISLHSLVDRAVKLNADI 155
WP_014271102  92 QLwsGRSR--I--FR-I------------GTQTTSGDQIDSILNACNVLVNKRRGALIVFPRRLGIKNIIDSGTRVNADL 154
WP_024268673  93 QL--GQGK--I--FR-F-------------KETAKPLQIDGVLKASQMLAQQRRGALVVFVRSVGQKNIVETGSTLNAEL 152
WP_010882270  94 KI--GEKN--W--LR-Q-------------RECAHHTHIDAVLTAADVLSKRKRGMLVVFARHHTVREVSETGTALYARL 153
WP_084792829 154 SKRILMSIFYKNSPLHDGAVIIHDDRVVAARCILPVSE-NSDLP-A-QFGLRHRAAIGMTESSDVLVVVVSEETGQISLV 230
AKM84741     179 KSELLIDFFGNGSVLGRGAAVIEANRIVAAGSTLLQPR-A-----KvLFSTTNPAVRKVAKDWGAVVVVVNKMVGDISLI 252
AOR39443     153 STELLLTIFHPNTPLHDGAVVINGDKIISAGVLLPLTE-DPKLS-W-KYGTRHRAAIGMTEVSDAACLVVSEETGDVSIA 229
NP_972512    154 SSSLLVTIFGHDTPLHDGAAIVQNGMIVSAGCFLPLSE-QQDIR-K-SFGTRHRAAIGVSEETDAVVLVVSEETGALSLA 230
WP_015905127 153 SREMLVSIFWHDNPVHDGAVIIQGNQVTDVGVILPLSK-RQDLP-S-YFGTRHRAAMGLAEQSDARVIVVSEETRKISLL 229
WP_013254238 153 SSSLLLTIFGHDTPLHDGAVIVSGGKLLSAGCFLPMSE-QTDIR-R-SFGTRHRAALGMAEDTDAVVLVVSEESGAISLA 229
WP_041177423 156 SIELVEAIFFKNNPIHDGAAIIMENRIAAASAYLPLTEiEPQIKnR-RLGTRHRAALGISEQTDAVVVVVSEETQCVSIV 234
WP_014271102 155 STSLILTVFDHDTPLHDGAMVIQNGRIVAAGCYLPLSE-QTDIK-K-SFGTRHRAALGMAEESDAVVLVVSEETGAISMT 231
WP_024268673 153 SSALLITIFGSDTPLHDGAVIIEDGKLIAAGAFLPLSE-QQDIR-R-SFGTRHRAALGLAEESDAVILVVSEETGAISLA 229
WP_010882270 154 SSSLLVTIFGHDTPMHDGAVIVRDGLVVSAGSFLPLSE-QHDIR-K-TFGTRHRAALGMAEKTDAITLVVSEETGALSLA 230
WP_084792829 231 RNGEISHNLSVQEIRRRLNAYLSTENNL-REE 261
AKM84741     253 HRDDVYKDLTPSELSKRLQTIFVYPSS----- 279
AOR39443     230 VDGALKKYEDLITLKADLEKILGYKEEV-EED 260
NP_972512    231 YDSHLYYDLSADEVVAQLEQLLEIKKYF-AQE 261
WP_015905127 230 KENRIYDINDSHVLetllngdlgtepshtgvr 261
WP_013254238 230 FDANLQYDLSSAEVAGTLRELLESPADE-KQE 260
WP_041177423 235 HNGILEYNLNREELDKRLGELLEIK----K-- 260
WP_014271102 232 YNANLYYDLDPLTIKRMLLALFSYHDIT-PEE 262
WP_024268673 230 YDATLYYDLEPEEVRSRLHELLNLDDEDfEQ- 260
WP_010882270 231 YDSKLYYDLPHADVLAQLKQLLETTTRA-GHA 261
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