Conserved Protein Domain Family
MenC

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COG1441: MenC 
O-succinylbenzoate synthase [Coenzyme transport and metabolism]
O-succinylbenzoate synthase is part of the Pathway/BioSystem: Menaquinone biosynthesis
Statistics
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PSSM-Id: 441050
Aligned: 47 rows
Threshold Bit Score: 332.229
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_012506426   3 PAHAAIYRYSIPFVRPVPVRQTSLDTRDGLVLALRSPd----------------------rQHTGLGEIAPLPGLHNESL 60 
NP_662725      3 PLHADICRYEMDFTAPVTVRGVLLARRQGLLLRLKSE------------------------GVTAYGEVAPLIGLHTESL 58 
WP_010944978   1 MRSAKLYRYVIPVETGTILRNRRLKQRDGLFIQLQDN------------------------QRVGWGEIAPLPEFSHETL 56 
WP_011745906   3 ASFLHLYRYSIPFNEPVTVRNHRLLNREGIIIALKSSd----------------------gAMISYGEIAPLPGLHEETL 60 
WP_012509096   3 ASHLVIYRYAIPFTEPITVKGHRLVQREGIAVALKSEe----------------------gGHTAWGEIAPLPGLHRETL 60 
WP_012621698   1 MKTAQLYRYSLPVETGIILRNRRLKQRDGLIIHLKHA------------------------DKEGWGEIAPLPEFSQETL 56 
WP_015432277   1 MRKFSLYRYQIPLQSGLILRAQTQRFRTGLICYLAEK------------------------HHEGWGEIAPLSGFSQESL 56 
WP_006249260   1 MRQVKLYRYQLPIQTGVVLRKQPLKERQGVLVCLQEQ------------------------EKVGWGEIAPLPSFSQESL 56 
WP_014991232   1 MRKAQLYRYQIPVETGVILRHRRLKQREGLIVKLTEE------------------------NQVGWGEIAPLPEFSQEDL 56 
WP_075479487   2 QRQVNLYYYQLPLDCAMILRGQSVSVREGWIVELQERvelqesaelqestglharcksthvNKVGRGEVAPLPGFSDETS 81 
WP_012506426  61 DEAFDELAATLRKKLpetgnltllnVSD----TLEE-RLYPSVRTGIEMALLNLQAsitgQFPElpcg--------pepA 127
NP_662725     59 DEALQALATFIPELSrld-----wnASDgrqrLLDEaALPPSVTTGIEMALINLEAtersSLPSftde--------fppA 125
WP_010944978  57 VEAEQQIRDWLVHWG----------EGD----LPDLtTYAPSVAFGVSCALAELGD----QLIQ---------------Q 103
WP_011745906  61 HMAEHQFMEYIYNHKl--------sTID----LLPE-GLFPSVKTGIEIALFNFKAvnsgIPPFfssp--------spsA 119
WP_012509096  61 QSAEAQLVGVLSRHDf--------aAPG----ILPE-ELFPSVRTGLEMVMINLEAltsgVPPLlsln--------ghvA 119
WP_012621698  57 AEAEIAVRQWIEKWL----------NHQ----DDSLtSYPPSVAFGVSCALAELNE----TLSE---------------E 103
WP_015432277  57 AQAENQALAWLTCWQ----------NGG----TQTLeALFPSVAFGLSMALYELRH----GLCE---------------A 103
WP_006249260  57 EQAENQAVNWLKAWQ----------KGE----PETLeQLFPSVAFGLSCALAELNN----ELGE---------------Q 103
WP_014991232  57 SLAQQQTEQWLAKWL----------AGQ----QDNLdSYVPSVAFGLSCALAELNG----ELTE---------------Q 103
WP_075479487  82 AQAKQQLESIIKIWL----------EQG----VVDLsMCYPSVAFGFSMALLELDD----ELPKmtycdnihndnihnsH 143
WP_012506426 128 TTLPLNALLFGDNATVLQQaeHFYQQGYRTLKLKVNALNKAD----ATGQIRTLDRVFgSSITLRLDSNQSFDLEAAIRF 203
NP_662725    126 SKIPVNALLAGDPQAVLNRaaKRYAEGFRAFKLKVRKGELDG----AVACIRALHEAFgDKAELRLDANQSLEFDEAVAF 201
WP_010944978 104 ANYRAALLCYGDPDELYSS--LTMMSGEKTGKMKVGLYEANR----DGLMANMLLEAL-PELHLRLDANRSWSLEKALKF 176
WP_011745906 120 SRVPINALLAGERESIIVRaeTLYNLGYRTFKLKVTPKNAEQ----TLGVIRELSLKFgETVALRLDANQSFSLDEAVEF 195
WP_012509096 120 AQVPLNALLFGDTELIMQRaeKYFALGYRTFKLKVTAGDTAN----AIRSINALHRAYgERITLRLDANQTLTLDEALEF 195
WP_012621698 104 ANFQTVPLCYGDPDELYAE--LNQIQGEKIAKIKVGLYEANR----DGLIADMFLEAI-PDLKLRLDANRSWTLEKALLF 176
WP_015432277 104 KSVLTVPLCSDSSLKTIER--LKQ-QNITIAKLKVGRYSPEQ----DAKTVQQLLNAM-PHLSLRLDANRAWDLNTASQF 175
WP_006249260 104 ANNQSAVLCYGDLEKLHTA--FSQ-HTNPIGKIKIGL-NPEQ----EGEQANLLLHTF-PNLRLRLDANRLWSLEQAVKF 174
WP_014991232 104 GNYRAAVLCYGDPDELYAE--LNALEGDKIGKMKVGLYEANR----DGLIANMLLEAL-PDLQLRLDANRGWTLEKAVKF 176
WP_075479487 144 NHINSALLLAADLRVINRK--HFQLAASSLCKLKIATQPTAKgarhDGEVTRQLLLRY-PQLRLRLDANQRWSLDAALVF 220
WP_012506426 204 LEALPK---KRIAYIEEPLSDPQKIAELFRRSGVPIALDESLWQt-----------------PDLRHALpDECLGAYILK 263
NP_662725    202 GKALPP---GCVAYIEEPLTDAALISDFHAATGLPSALDESLWQr-----------------PELLDEIgPDPLGALVLK 261
WP_010944978 177 AEKIADqhkAQIQFIEEPCQTPELSRQFAQQSGIAIAWDETVRE------------------ADFVVKK-EPNLAAIVIK 237
WP_011745906 196 SKNIIR---DNISYIEEPLTDPILIGEFHARTAVRSALDETLWQq-----------------PYLMRSFpPGALKALVLK 255
WP_012509096 196 ARHLPR---NSIAYIEEPLKEAELIGEFFAKTAIQTALDETLWQk-----------------PDLLFQIpEASLAALILK 255
WP_012621698 177 ASKIASerkKRIQFLEEPCKTPELSRQFAEQTGINIAWDETVRE------------------PDFLVKK-EPNLTAIVIK 237
WP_015432277 176 ALRLSPaekRQIVFIEEPCQTVEQSLQFAKNQQIAIAWDESLQL------------------KEVQLQI-QEGLAAIVIK 236
WP_006249260 175 AEKIANehkPRIQFIEEPCQALELSRQFATQTDIAIAWDETVRE------------------ANFLVKK-EPNLTAIIIK 235
WP_014991232 177 AEKIANenkSRIQFIEEPCKTPELSRQFAQVSGIAIAWDETVRE------------------PNFVVKN-EPNVTAIVIK 237
WP_075479487 221 AKQIPValrQRIDFIEEPCHRPNDSYLFTRETGIALAWDESLRDackkprgqgngefmkstiAECNASE-TASITAIVIK 299
WP_012506426 264 PSRIGGITATMKLAIEAEAKGIPAVISSGFESGISLGFYAKMASLLGPnPTACGIDTFRQFTKDILITplcSQsGSLCVe 343
NP_662725    262 PNCIGGIAKSLDLAAKAHRMGLQAVYSSAFESSVSLGLYALMAAVSSPaPAASGLDTASFLARDLTATpfaTPdGFADPa 341
WP_010944978 238 PTLVGSLQKCIGLIEQAHQQGLIAVISSSLESSLGLTQLARFAQQYTP-CTMPGLDTLNLMKTQILRQ---WP-NSNLP- 311
WP_011745906 256 PNRLGGIVETLRLAQYARENNLLAVLSSAFESGISLSFYAWLAAHTSTePAASGLDTGRYLEYDLLDLpfgSSsDTLTPq 335
WP_012509096 256 PNRLGGISATRQLARYARKHNLLAVFSSAFESGISLSFYTLLAASTAVkPAACGLDTFRYLEHDLLEApfgAEnALLDPr 335
WP_012621698 238 PTLVGSLEKCISLIEQAHQQGLIAVISSSIESSLGLTQLARFATQYTP-NTLAGLDTLDLMKVQLLRE---WN-NSTLP- 311
WP_015432277 237 PMLIGSREKCLAMIKQAHLLGLQAVLSSSIESSLGLSQLAHFAEQVTP-QTAAGLDTLSLMQQQLIRA---FP-LSSLP- 310
WP_006249260 236 PTLVGSLEKCVNLIQQAQKQGLVAVISSSLESSLGLTQLARIAQQYTP-NSVPGLDTLNLMQHQLLRD---WH-DSSLP- 309
WP_014991232 238 PTLVGSLQKCIRLIEQAHQQGLSAVISSSIESSLGLTQLARLAQQYTP-ETTPGLDTLDLMQYQLIRP---WK-HSILP- 311
WP_075479487 300 PMLTGSIIHCRNLIEQAHQLGLTVVISSSLESSFGLLQLARLSQWLTP-DTTPGLDTLHVFKQQVAMP---YP-GCNLP- 373
WP_012506426 344 siwrrstAPDMSRLTCIEQWT 364
NP_662725    342 aawrdslRVRPDMIETVKSWS 362
WP_010944978 312 -------IADLNSPFITELVL 325
WP_011745906 336 elywnghKVATSHLKPSSIWT 356
WP_012509096 336 klyregaNVRERSLKRVSLWT 356
WP_012621698 312 -------IVHLNSPYILGLDD 325
WP_015432277 311 -------LYGIESSFLQKIA- 323
WP_006249260 310 -------LVGLESEFVREVVV 323
WP_014991232 312 -------IADLDSPFVQEIML 325
WP_075479487 374 -------LIALAALPCRCYFQ 387
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