Conserved Protein Domain Family
CYTH

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COG2954: CYTH 
CYTH domain, found in class IV adenylate cyclase and various triphosphatases [General function prediction only]
Statistics
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PSSM-Id: 442195
Aligned: 219 rows
Threshold Bit Score: 105.635
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
AHB41447       1 M----LEIERKFLLNEIPNDIATc-EKQEILQGYFKENKK--NIRVRKtisykKGRKytSYTMT-KKqGS------GLIR 66 
BAN02099       1 Mg---DEIERRFLVDDVPSGTAVe-SDERLEQGYLAIDGAa-VVRVRR-----SERG--WVLCI-KG-GS------GLVR 60 
WP_012198857   1 -----MEIERKFKISKLPANLEQy-KKKEIIQGYLCTQp---VVRIRK-----SNEN--YILTY-KN-KSnfnqehAVIS 62 
WP_015818089   1 Ms---EEIERKFLLNELPADIATwpQPAAILQGYLQKDQHk-DLRIRK-----KGNK--YTLTA-KH-GT------GLVR 61 
WP_013656146   1 -----MEIERKFLVQDYP-SLEAy-SSEKITQAYISTDp---VIRLRE-----MGNQ--YFLTV-KS-QG------HMIR 55 
WP_066053611   1 -----MEIERKFLTKEIPFSLDKf-LCKQIIQAYVSFQp---TIRIRK-----SQEQ--FFLTV-KG-KG------HVAR 56 
WP_017467355   1 MtdssQEVERKFLVAEMPPLDGA--VSEHIRQGYFTVPEDsvQVRLRQ-----KGAR--FFLTV-KG-QG------TLSR 63 
WP_088921141   1 Ma---IEIERKFLVEELPVIELQnaVLEEIQQGYLIREADr-EVRIRR-----KGEL--FFLTE-KK-GA------GLSR 61 
WP_117315525   1 Mhg-kWHFERRFIVSYIPGSLLQaaSVDKITRGYLSCAEEk-QIYVQD-----TNGQ--PTLSVvQ--GS------GLKR 63 
WP_111525845   1 Me--nIEIERKFLINEIPSDLDVy-ERIDMIQGYLNTNp---VVRIRK-----ENDD--YVLTY-KG-SG------LLSH 59 
AHB41447      67 QEIEKKLSEKQFGDYREFAKTYQIKKTRYLYPH-KKQIIEINQFHDKLDGLRMAEIEFGSGEesQKFIPPSRCDKEVTER 145
BAN02099      61 TEVERDLDVAEGEQLWELTLGRRIGKLRQRIRLdHGLVAELDTFDIDLDGLQIVEVEFDSEAaaAAFVPPAWFGRELTDD 140
WP_012198857  63 EEIELPLTKEAFEHLLSKVDFGVIEKTRYLIPLsQDHTAELDVFHGRLSGLMFVEVEFSSEKdaIDFIKPDWFEEDVSKD 142
WP_015818089  62 EENEQEIDKTLFDILWPFTAEARIEKLRYTRVI-DEGEMVIDKYLGDLSGLLLMEVEFNDEQlaRTYSPPLNFAKEVTDD 140
WP_013656146  56 EEFEMPITKEQYDSLYKKVDSSPIKKTRYFIPLeNQLTAELDIYQGHLDGLCTVEVEFTSVAaaDSFKAPQWFGKDITLD 135
WP_066053611  57 EEFEIEINQHEFEGLLKKTDGNCIRKKRYYIPIeSGYTAELDLYEGELEGLMTTEVEFPTLEeaETFVAPWWFGKDISLE 136
WP_017467355  64 SEHETEIPAEVFERLWPATGARRLEKIRWTGRLpGGEVFELDLFED--RDLRLVEVEFADETgaLEFVPPDWFGREVTED 141
WP_088921141  62 EEHEISINEQMFDALWPLSKGMRLEKARSTFML-DGYQLELDVYHGELKPLMVLETEFTSEEeaLAWSPPEFAGLEVTGD 140
WP_117315525  64 QTEVIALSAEQFSTLWEQTQGLRFAGEKSQIKH-AGQPVELMAYTGNLAPLKLVVVTFANEQqcREFIQPDYVHTEVTHH 142
WP_111525845  60 SEYNLPLDKESFNHLLKKCDGIIISKSRYKIPLeNSLVAELDIFKSDLSGLVLVEVEFKSVEeaSNFTPPKWFGEDVTED 139
AHB41447     146 KDANNSYLAVYgmnklirninyqdiitrfQLKSF 179
BAN02099     141 PRWSNVALATTg----------------rPDTGT 158
WP_012198857 143 KRYRNSYLISVs----------------sLEELH 160
WP_015818089 141 PRYRNAALAAHg----------------tPAI-- 156
WP_013656146 136 NRYKNNNLATYg----------------vPTEK- 152
WP_066053611 137 MGYKNTALALYg----------------kPKEEV 154
WP_017467355 142 GRFSNSSLASGg----------------vPDASP 159
WP_088921141 141 KRYKNAQLAKTg----------------kPDNG- 157
WP_117315525 143 KDYTDMALARi------------------GLPDI 158
WP_111525845 140 NRYHNSYISKYg----------------lLKWRY 157
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