Conserved Protein Domain Family
CDK5_activator

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pfam03261: CDK5_activator 
Cyclin-dependent kinase 5 activator protein
Statistics
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PSSM-Id: 460866
Aligned: 8 rows
Threshold Bit Score: 417.365
Created: 21-Aug-2024
Updated: 4-Dec-2024
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_002014398  95 HHLHNLANSskdTITNVLD--------AQNENGAIKSEKSSI----DKNLKKHSIFINALSWKKL---STS-HNKKKIDN 158
2_pfamImport   1 SPLPHRPQT---SVCNHLFs-------PGDGGPTFAPQQQES----PRPSAKESVLVQGWNWSKR---NIQpVMSRRSLL 63 
Q9V3H5        96 HNLNNLANAskdTITNVLD--------THNENSVLKAEKSSF----EKNLKKHSIFINALSWKKL---STS-HNKKKIEN 159 fruit fly
XP_002060110  95 HNFNNLAYSskdTINNDLD--------AHNENSTVISEKSSI----EKSLKKHSLFINALSWKKL---STA-HNKKKVEN 158
XP_002430721  55 NNNNNNNHTtsnTNNNNTNhqihanhiNNNDNAKIISEKNTL----EKNFKKHSLFINALSWKRF---STAnNNKKKLDN 127
1_pfamImport   1 GPATVGHYTavqNSKNAKD----------------------AaaaaAKSLKRPSI-ISVLPWKRIvavSAKrKGSKKLQS 57 
Q22695         7 SPLPHHHRTqttSVCNHLFs-------PGDGGPTFAPQRDSNtssrSSSNAKESVLMQGWNWSKR---NIQpVMSRRSLP 76  Caenorhabditis ...
3_pfamImport   1 SPLPHHHRTqttSVCNHLFs-------PGDGGPTFAPQRDSNassrNSSSAKESVLMQGWNWSKR---NIQpVMSRRSLP 70 
XP_002014398 159 -KNKCANLPTACFKSQFLESTFASS-------------SDKNRNIQLQCNRieehnqpn--------------------- 203
2_pfamImport  64 kSSNMSEATSSKSSNSLVSFTCNAStfttkqsekttvsLDKNQNYKVNAVNdenkeldvl-------------------- 123
Q9V3H5       160 -KNKCANLPTACFKAQLLESSFASS-------------SDKNRNIQLHCNRidehnqqhcnqhphphphqhqlqlqnqhq 225 fruit fly
XP_002060110 159 -KNKCANLPTTCFKTQLLEASYTSS-------------SDKNKNIQLHCNHieehqhqqh-------------------- 204
XP_002430721 128 -KNKNLTI----FRQPLLD-NIHPI-------------VDKNKNIHKSTSI----------------------------- 159
1_pfamImport  58 dSGDGGKGSSPDGHAAATTNSASNSl-----------kLKKSQS------------------------------------ 90 
Q22695        77 kSGSSSEATSSKSSDSLVSFTRNVStstssqygkisisLDRNQN------------------------------------ 120 Caenorhabditis ...
3_pfamImport  71 kSGSSSVFQKQHHRNPVIVLFLSLEmlgll----lpvnMGKYQYHLTGIII----------------------------- 117
XP_002014398 204 ---------hnqpqdirEDSGT-VTAKSQNPSKVKd----------------sIKVNNKNSICNHNKLIQK--QPLTLSL 255
2_pfamImport 124 ---------rfvnldssTSTSFySTWYKRIPRSVDqttiipnyyslreefrrgVEINHGHDAVNNNLNENG--NEYSISS 192
Q9V3H5       226 hqnqnqnqnqnqvqdirEEVMTgPPGKSQNPSKAKd----------------pVKVNNKNSMSNHNKLIQK--QPLTLSL 287 fruit fly
XP_002060110 205 --------hcnqshiirELPLF-PSTKAQKPSTAKe----------------lGRVNNTNSISNHNKLIQK--QPLALTL 257
XP_002430721 160 -----------------PCYYPcLTVSKTVPSLSNpeeldg------hvdinlRSNNNSNNNANTNNTSSSfcEKLGPKT 216
1_pfamImport  91 ------------------CANLsSYSSSQDPAATTtttssh-------lpaskTLANVATVVAKKN-------------- 131
Q22695       121 --------------------------YKSVPRPSDtttiipnyyslreefrrgLQINTRQDLVNNNLAS----NDLSVIG 170 Caenorhabditis ...
3_pfamImport 118 --------------------------ISEIPRP-DsttiitnyhtlhnefkrnCQINNRQDLVNNNLTA----NELSIIG 166
XP_002014398 256 P-----QQMQPSSMQFKNNNQ-----------------FPRKTVIQASTSELLKCLGIFLHCRCqRLSNFDAGDAVMWLR 313
2_pfamImport 193 SpkhvaKCTIPRLINPDDNGNedlinyegdamlpesanGKRRTIIQASTSELLRGLGIFIANHC-TVKDFNPVHLVTWLR 271
Q9V3H5       288 P-----QQVQASSIQTKNTNQ-----------------IPRKTVIQASTSELLKCLGMFLHCRCqRLNNFDAGDAVMWLR 345 fruit fly
XP_002060110 258 P-----QQLQISSIQIKNTNQn---------------hLPRKTVIQASTSELLKCLGLFLHYRChRLNKFDPGDAVMWLR 317
XP_002430721 217 NlsnipQSQTSSAISNSSHHQv----------------PPRKTVIQASTSELLKCLGIYLHNKCyRLKDFQAGDAVMWLR 280
1_pfamImport 132 -------SLTGSGIQPSTAAG-----------------TPKRVIVQASTSELMRSLGEFLCRRCyRLKRLSPTDPVLWLR 187
Q22695       171 SpkhvpR---PRSVLRDDNANcdispia----------eqenvpsEASTSELLRGLGIFISNNC-DVSDFDPAHLVTWLR 236 Caenorhabditis ...
3_pfamImport 167 SpthvpR---PRSI-RDDNANdecdqqe---nyisekrGTKKTIIQASTSELLRGLGIFISKNC-DVSDFDPAHLVTWLR 238
XP_002014398 314 AVDRSLLLQGWQDVAFINPANVVFVYMLVRDLVDGEE---SKESDLQASVLTCLYLSYSYMGNEISYPLKPFLVEDSKDK 390
2_pfamImport 272 SVDRSLLLQGWQDIAFINPANLVFIYMLVRDELPGERhliNTLEELHAWTLSCLYVSYSYMGNEISYPLKPFVIGNDRAK 351
Q9V3H5       346 AVDRSLLLQGWQDVAFINPANVVFVYMLVRELVSGEE---SKESDLQASVLTCLYLSYSYMGNEISYPLKPFLVEDSKEK 422 fruit fly
XP_002060110 318 AVDRSLLLQGWQDVAFINPANVVFVYMLVRELVNGEE---TKESDLQASVLTCLYLSYSYMGNEISYPLKPFLVEDSKEN 394
XP_002430721 281 TVDRSLLLQGWQDVAFINPANVVFVYMLIRELVEGNE---ETEHELQILVLTCLYLSYSYMGNEISYPLKPFLVEDSKEQ 357
1_pfamImport 188 SVDRSLLLQGWQDQGFITPANVVFLYMLCRDVVSAEV---ASERELQASLLTCLYLSYSYMGNEISYPLKPFLVEAEKEA 264
Q22695       237 SVDRSLLLQGWQDIAFINPANLVFIFLLVRDVLPDERhliHTLEELHAWILSCLYVSYSYMGNEISYPLKPFLIGNDRNT 316 Caenorhabditis ...
3_pfamImport 239 SVDRSLLLQGWQDIAFINPANLVFIFLLVRDVLPDERhliRTLEELHAWILSCLYVSYSYMGNEISYPLKPFLIGNDRNT 318
XP_002014398 391 FWDRCLVIVNKLSDKMLKINAEPGFFTEVFTELKSCGQY 429
2_pfamImport 352 FWNRCMSMVTTHSRKMLLLNSSSSYFSEVFSDLKHCLTE 390
Q9V3H5       423 FWDRCLVIVNKLSDKMLKINAEPGFFTEVFTELKSCGQY 461 fruit fly
XP_002060110 395 FWDRCLFIVNRLSSKMLKINAEPAFFTEVFTELKSCGQF 433
XP_002430721 358 FWDRCLNIVNRLSRNMLRINAEPGFFTEIFTELKGCGAT 396
1_pfamImport 265 FWDRCLDIINRMSGKMLQINTDPHFFTQVFADLKNESKK 303
Q22695       317 FWNRCVAMVTSHSRQMLLLNSSSTFFSEVFTDLKHCSSS 355 Caenorhabditis elegans
3_pfamImport 319 FWNRCVSMVTSHSRKMLLLNSSSTFFTEVFTDLKHCSSP 357
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