Conserved Protein Domain Family
CAP59_mtransfer

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pfam11735: CAP59_mtransfer 
Cryptococcal mannosyltransferase 1
The capsule of pathogenic fungi is a complex polysaccharide whose formation is determined by a number of enzymes including, most importantly, alpha-1,3-mannosyltransferase 1, EC:2.4.1.-.
Statistics
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PSSM-Id: 432033
Aligned: 184 rows
Threshold Bit Score: 180.814
Created: 24-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
CAM45646      288 HFYIALNLWKNE-EVLPDLTEALIVFLEedvkpFF--DlatSVVVAIYSNISPDRTSELIAtLLIPRLHAAGVRNVYatt 364 
XP_007849496  156 KYFFAINLYNSF-DIIPDLFATLFRISA-----ILgpQ---NIYVSIYENGSTDQTKALLR-IFDALTKSVGLRVTIrts 225 
CCA72951      137 KYFFAINLYNSF-DVIPDLFSTMFRVAA-----IVgyN---NVFISIYENGSKDQTKALLN-IFDSLLKSVGIRVVIkts 206 
EKC98868       15 KYFIAINLYNSF-DVIPDLFSTLFKTAA-----VLgyH---NVFVSIYENGSKDQTKALLR-LFDALARTVGLRVTIrqs 84  
ERS96149      142 TYFFALDLRRVV-GLLPTLLGSVVEAVR-----FLgpA---NCVVSIVEGHSNDGTYETLL-LLQNALNAMGAVVYIqst 211 
OBR09080      117 HYFFALDLRQVR-DLLPQLIGAVLEAMN-----VIgpE---NCALSVVEGISTDGTYETLY-RLKAHMDKMGVAYYLqts 186 
XP_008078737  157 KYYFAINLHDSI-QIIPRLLGSVVETMR-----FLgfD---RCTLSIIEGRSVDGTYEVLK-SLAPALGKLGVTYHFnss 226 
XP_003047949   63 dyIFAVRVVNNLdQL-PTLLGAVLNAMY-----YLgpY---RCALTVISSGWRPHLDDVLE-ELHLGLNHIGAVYNYtsf 132 
CCA69865      156 lYYIAIIIHSAD-HFLVDQLAVIIQMAR-----RIgpQ---SIFVSMLDYDSDDATPTLLD-LCEAVLTLLAVPFRI--- 222 
XP_566939     157 lYYIAIVIHSAD-HFLVDQLAIIVQLAR-----RLgtR---NIFVSMLDHASTDSTPTLSD-LCEAVMTILGIAFRI--- 223 
CAM45646      365 egtclgyvErqpFHERIEWM-------------ACIRNKALEPLYE---KGMnVFggsqQQqqeqqadvngdadglvVLF 428 
XP_007849496  226 mrt------rgafnhRIEYL-------------AEVRNAAFLPLHElrdAEGeIF----DT----------------IVF 266 
CCA72951      207 qrt------rgafnhRIEYL-------------AEVRNAALVPLHElrdRQGeYF----DT----------------IIF 247 
EKC98868       85 mrt------rgafnhRIEYL-------------AEVRNAAMTPLHElreNEGeVF----DT----------------IVF 125 
ERS96149      212 -----sinPl--FGDRIGKL-------------AKLRNLALEPMHLesa---nmHp--dQs---------------vILF 251 
OBR09080      187 -----sidSh--SGDRIGKL-------------AKLRNLALEPMMAeaaa------ydpKa---------------tIVF 225 
XP_008078737  227 -----dvnPe--VGNRIGNL-------------AALRNDALEPLRAspt--------yeNa---------------sVIF 263 
XP_003047949  133 ay---------------------------gpraYKHRNQAIGAVrharke---------------------vsedatIVF 164 
CCA69865      223 --------------RHVPRMtedrknsyypqeeAYTRNLALEPLWElreRRGiNF----HR----------------VIW 268 
XP_566939     224 --------------RRVPPMtvdpsaayypleeAEARNLALEPLHElwkKRSiKF----HR----------------VIW 269 
CAM45646      429 FNDILFHPQDITALLESraeArmaatTrphgwlssvmktkhesaevadagiggkgnlekrhvsttsplpsgatsttpptt 508 
XP_007849496  267 MNDILPCVDDILELIYQsrlN-----N----------------------------------------------------- 288 
CCA72951      248 MNDILPCVDDVLELIWQsrrQ-----N----------------------------------------------------- 269 
EKC98868      126 MNDILPCVDDLLELIWQsrrQ-----N----------------------------------------------------- 147 
ERS96149      252 LNDVAACTEDLLELALQrrrQ-----H----------------------------------------------------- 273 
OBR09080      226 LNDVAACTEDILELAYQkqvQ-----G----------------------------------------------------- 247 
XP_008078737  264 LNDVAICMEDILELVHQritL-----E----------------------------------------------------- 285 
XP_003047949  165 LDDVDICSEDILELILQrenL-----G----------------------------------------------------- 186 
CCA69865      269 LKG-FTCPYDILETIKVselN-----S----------------------------------------------------- 289 
XP_566939     270 LKG-FTCPNDVLESLRVsqlN-----N----------------------------------------------------- 290 
CAM45646      509 FDMACGMDFYF----------TFYDTWITRDRLGKPF---------------------KPQMPYSDD----RATQEAFYR 553 
XP_007849496  289 AGITCAADYMYhsei---qspVFYDNWVARDINGTALe-------------------nAP----FEMilhhPESSARFQA 342 
CCA72951      270 AGVTCAADYMFhdei---gapVFYDNWVARDINGTALe-------------------nAP----FESifhhTPSSDRFQR 323 
EKC98868      148 AGITCAADYMYhdei---gapVFYDNWVARDLNGTALe-------------------nAP----FEQvfhhPESNSRFQR 201 
ERS96149      274 ADMACAMDYHrldrqy-dykltFYDVWISRTMDGEAFimappglaq---wrfaddlfpYD-----------DLARARYAQ 338 
OBR09080      248 ADMTCAMDYHflrfaphngepsFYDSWISRAINGDTFlpipdrtpkgeqwsdvanmfwNH-----------PYSQDRYLG 316 
XP_008078737  286 ADMVCGMDWKnlw-----kdpTFYDVWIARTMTGDSFfevgedgnw----dsawnlfwSD-----------DKTQQRFQD 345 
XP_003047949  187 ADMTCGMQWAPnksn---gipLLKNDGTCRDMQGERFghvppe----------kwtegTDVKEYFWKs---SKDQARFNE 250 
CCA69865      290 AAMVCGMDWAefn-----gafIFSDRWRARDMDGDVFrrarssa-------paesgppRH-----------AVSATRYGS 346 
XP_566939     291 AAMVCGMDWAehn-----gffIFSDRWRTRDIEGNLFraaksns-------kpeagppRD-----------KAGTERFSH 347 
CAM45646      554 ifnhepsggyapetsAIPVKCCWNGL-AAIRGRFFlPPtpqHR-LEFPAQ-------DAAETTVR 609 
XP_007849496  343 h-------------lPIQVQSCWNGI-AVLDPAPF-YEp-pHVrVRFRMAritegecSASECSLI 391 
CCA72951      324 h-------------lPVQVQSCWNGI-AILDPAPI-YSt--PH-VRFRMArlvdgecSASECSLI 370 
EKC98868      202 h-------------lPIQVQSCWNGV-AILDPAPF-YEq--PH-TRFRMAdllkkecSASECSLI 248 
ERS96149      339 r-------------rPFQVFSCWNGA-VALTARPF-FD---KK-VEFRRAyknvgecGAGEPTLL 384 
OBR09080      317 r-------------kPLQVFSCWNGG-VAVTGEPF-LA---KR-LDFRRSyqg--ecHTGEPTLL 360 
XP_008078737  346 h-------------lPFQVFSCWNGG-AVFGARPF-FK---TA-IEFRAPreg--ecFNGEPAIF 389 
XP_003047949  251 k-------------rPFQVFSCWGGA-AAFTASTF-TR---LE-QIFRLPikg-aecTQPDTRLF 295 
CCA69865      347 h-------------lPFQVFCCESGThIVDPAQSY-Y----KG-IKYRHGthf--ynSTREDLVI 390 
XP_566939     348 h-------------lPFQSFCCESGThIVDPEQSY-Y----RN-IHYRAS-------SSAHNISI 386 
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