3LKV


Conserved Protein Domain Family
PBP1_ABC_unchar_transporter

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cd06325: PBP1_ABC_unchar_transporter 
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type 1 periplasmic ligand-binding domain of uncharacterized ABC-type transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions
This group includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type transport systems that are predicted to be involved in the uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); its ligand specificity has not been determined experimentally.
Statistics
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PSSM-Id: 380548
Aligned: 456 rows
Threshold Bit Score: 158.051
Created: 9-Aug-2006
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
 
ligand bindingZn binding site
Conserved site includes 9 residues -Click on image for an interactive view with Cn3D
Feature 1:ligand binding site [chemical binding site]
Evidence:
  • Structure:3LKV; Vibrio cholerae conserved domain protein binds phenylalanine, contacts at 4A

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                                                                         ###         
3LKV_A     10 KVAVSQive-hpALDATRQGLLDGLKakgyeeGKNLEFDYKTAqgNPAIAVQIARQFVGeNPDVLVGIATPTAQalvsat 88  Vibrio cholerae O1...
SLM44046   46 DVVILKs-----SDIAAYNQAISGFKaa---lPNDVVLAEYDLqgDLEKGRKLARKIRAaDPALVFAVGLKAAKaaqlei 117 Nitrospira sp. ND1
PIV19984   32 QIGIIQwaespiDYTRTCEGFIGGMKesgyeeGKNVHFDIQIAdgKRERAKEIARGFVEkKVDLICALGTIPSLvalegt 111 Deltaproteobacteri...
OGQ80320   15 DLVVVVksrevePYEIALKSLRRTLKes---gYDPIIGEYLLPegGQEKSGLLADIRKK-DPRLIVTLGSAATSqiskai 90  Deltaproteobacteri...
OIO39370   34 DIAVLTsgd-vkQYEEALDGFKEILGs----nSIKYSIVEFDLkkEKDPEKLIKKLLSE-EPHLVLAMGSQATElikeki 107 Candidatus Omnitro...
OGJ89430   24 SIAILMqq---eKEGALSEGPLAGFKa----iAGPDVAQFEIT--DPGAAQAICAKIKAsGAKVVFTIGKDATKaamqel 94  Candidatus Raymond...
SNB45783   29 LAAVISsd--qpRYREAHKALVKSLAarg-fdRDNLDIVLQTPnpDPISWANSIRKLNAlGADIIVTYGAPVTLaavres 105 Geobacter sp. DSM ...
KPL04711   27 RIVIVKtss-siPFLKAEEGFKKEIRks---eIETILIEYEASn-ESREEGEIAQKIRDlKPDLIVTIGSRSTAivsqei 101 candidate division...
OHB27294    7 FVAVIItgd-ieRYRLAHEAFVQKLRdsg-msEERLNIYVQSPnpDTMSWNNSIRKAVGiGADVIVTYGAPATLsakkea 84  Desulfuromonadacea...
AMV72334   30 FVAVIItgd-lpRYQQAQEAFMKILRagg-ldESKVEVYTQTPnpDPISWANSIRKAVGvNADLIITYGAPASLvakrea 107 Desulfuromonas sp....
Feature 1             ###                                                     #               
3LKV_A     89 KTIPIVFTAVTDPvgaklvkqleqpgkNVTGLSDLSPVEQHVELIKeilpNVKSIGVVYNPGeaNAVSLXELLKLSAakh 168 Vibrio cholerae O1...
SLM44046  118 VDIPVVYAMVLDPakyg------lnapNMTGVLMEIPMERQLIMIKsllpRLKHVGTLYDPS--KTATLIEDARRLLksn 189 Nitrospira sp. ND1
PIV19984  112 KEIPIVYSIVGEPkatgviqswvssgrNITGVSMKIPMEKQLEMVRkavpKLRRLGILYCLStpQAIVTAEEANQTAkkl 191 Deltaproteobacteri...
OGQ80320   91 KDIPVTFCMVLNPlasgfvrsmdasgnNLTGASLDIPIQAQFEALRsivpSAKKIGVIYNPQ--ETESVVLQARRIArem 168 Deltaproteobacteri...
OIO39370  108 GSVPIVFSMVLNPvssgfvksiaspggNIPGSSLDISLKTQFEEFKkmvpGLKKVAVLYNPG--ETKMVVDNAGSVArgm 185 Candidatus Omnitro...
OGJ89430   95 PGMPIVYCMVMSPqedg------igggSVTGVTLDIPMVKQFTSFKsvvpNLKKIGIVYSDE--TSGIIAKEMKAAAvkt 166 Candidatus Raymond...
SNB45783  106 VDVPVVFVDVYGPvetgitrsltvaghNLTGVSSKVPMTTLISNFLgi-kPIKNIAVVYNSReiGSMVQLKEIKRIAaqq 184 Geobacter sp. DSM ...
KPL04711  102 KDIPIVFCTVLNPvssgfvqnmrfsgnNMTGASLDIPVRIQLEKFKlvvpQLRRLGVLFTPDskQVITEARRVCQNI--- 178 candidate division...
OHB27294   85 RGIPVLFADVYDPvrlglirdigvpmkNIAGVSGKTPLETLLKTFHei-cPARTMGVLFSSNdeGSVLQLRKLAELSqki 163 Desulfuromonadacea...
AMV72334  108 RRLPVLFADVYDPvrlglvkdlavpggDISGVSSKTPVETLLRTYVdi-sKGKRIGALFSPDdpGAVLQVDDLENAAthl 186 Desulfuromonas sp....
Feature 1                                        #                          #                 
3LKV_A    169 GIKLVEATALKs--aDVQSATQAIAEKsdVIYALIDNTVASa--IEGXIVAANQAkTPVFGAATSyverGAIASLGFDYY 244 Vibrio cholerae O1...
SLM44046  190 GTELVPIPLNNe--rDVPGALRTLLPSidALWLVPDSTVLTdesLRFILNTALEErVPVVGFSREfarsGALLCLSVNYG 267 Nitrospira sp. ND1
PIV19984  192 GMTPHLRSLHSdqldRLPSVTGSVAKEveAIYIPTDPILTAkenLLKMIEITYRFkIPIIGVSDNavelGALMALHCDFR 271 Deltaproteobacteri...
OGQ80320  169 GLELVGAAINSe--eKVPEALRALDKSadTLWSVADSTAFSsgsMKVILLHTLQNkIPFMGLSPAfvkaGALLALDADYQ 246 Deltaproteobacteri...
OIO39370  186 GIELLPIKVLSe--kDVPEAMKAVSKDadALWAVADSTVFTkasSEYILLETLRNkIPFMGLSPAfvkaGALFSLSWDYT 263 Candidatus Omnitro...
OGJ89430  167 GVTVIEKKVASd--kDVPNAIRELKGKidGLYLPPDRTVANrdaFQFIALFTFENnLPFMAPAGRfvkkGALVALMIDFE 244 Candidatus Raymond...
SNB45783  185 GFLVTELNVSSv--aALDGALNSVISQvnSIYVSECAVGCRg--FEKIVQKANEHrIPVVSQMPDacekGALISLEVSPA 260 Geobacter sp. DSM ...
KPL04711  179 GIELVPELIYSe--kEVPGAVEALAQEvdGLWAVADTIIFTpqsTQYLLLHTLRNgLPFMGLSSSfvkaGALFTLACDHK 256 candidate division...
OHB27294  164 GLATLPKDISSp--nEVVTALKSMTGAi-DSLFVTDSAVLNm-rIKDIMNFSATQnLPVVSQIPTlcdqGALVTLESDPV 239 Desulfuromonadacea...
AMV72334  187 GLKVERQGVGKa--nTLGKSCEDLCSRvdALFVADSALLQMq--LPEILAIAAKNkLPVLSQIPGlsdlGGLITLEADPT 262 Desulfuromonas sp....
Feature 1                                                      
3LKV_A    245 QIGVQTADYVAAILEGkep-gslDVQVAk--GSDLVINKTAAEQLGITI 290 Vibrio cholerae O1 biovar El Tor str. N16961
SLM44046  268 DIGRQAGQLTRKILDGhl---slPAKPLhpdRIEMSLNRKTAKFLDIEI 313 Nitrospira sp. ND1
PIV19984  272 EIGKQAAPMAVKILNGmkp-mdiPSQMPl--GHRLTVNLKTAKQLGISL 317 Deltaproteobacteria bacterium CG03_land_8_20_14_0...
OGQ80320  247 EVGAQCGGLAAKILTGdrp-sslPITTPq--KATLHVNLNTAEIIGLKI 292 Deltaproteobacteria bacterium RIFCSPLOWO2_12_FULL...
OIO39370  264 DIGRQSGEIALKILKGeea-saiPVSVPr--SVKISVNNNTASRIGVKI 309 Candidatus Omnitrophica bacterium CG1_02_49_10
OGJ89430  245 ELGKQAAAMAKKIVGGasp-ssiPVEPPq--ATILVLNQKTAQTIGINI 290 Candidatus Raymondbacteria bacterium RifOxyA12_fu...
SNB45783  261 EQGQLAGEYAARIIGGkkp-lqmPIISPk--KVDLVINMRVAKSLDLHV 306 Geobacter sp. DSM 9736
KPL04711  257 DVGRQAGELALRVLSGekp-sqvPITIPr--MIYLCLNLRTAEQIDLEI 302 candidate division Zixibacteria bacterium SM1_73
OHB27294  240 EQGEVAAGLLISLLAGtpt-atmELHTPr--KVSLVINLLVARKLNLKV 285 Desulfuromonadaceae bacterium GWC2_58_13
AMV72334  263 EQGQLVGVHALQILTGmqkalalPVRTPk--KVALVINMKVAKELNLTV 309 Desulfuromonas sp. DDH964

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