Conserved Protein Domain Family
RPI_actino

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TIGR02133: RPI_actino 
ribose 5-phosphate isomerase
This family is a member of the RpiB/LacA/LacB subfamily (TIGR00689) but lies outside the RpiB equivalog (TIGR01120) which is also a member of that subfamily. Ribose 5-phosphate isomerase is an essential enzyme of the pentose phosphate pathway; a pathway that appears to be present in the actinobacteria. The only candidates for ribose 5-phosphate isomerase in the Actinobacteria are members of this family.
Statistics
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PSSM-Id: 273989
Aligned: 7 rows
Threshold Bit Score: 183.042
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
BAC73138       1 MYLGSDHAGFELKNHLVEWLKAAGHE--PVDCGPHIYDAQDDYPPFCLRAAEGAAADPDA----LGIVIGGSGNGEQIAA 74  Streptomyces av...
AAO44494       3 GRVHLATDHAGYEFSKGLLNFLADEH--YQVVHHGAVNCDPEDDYPSFCIAAAEAVVRDItdgiPSLGVVIGGSGNGEQI 80  Tropheryma whip...
AIJ15825       1 MRVYLGSDHAGFELKNHLVEWLAAAG--HEPVDCGPHIYDAQDDYPPFCLRAAERTAADQ----GALGIVIGGSGNGEQI 74  Streptomyces li...
WP_006768321   1 MRVYLGADHAGFETKNAIAEHLKAHG--HEVIDCGAHTYDPDDDYPAFCIEAANRTVNDP----GSLGIVLGGSGNGEQI 74  Corynebacterium...
WP_011728942   3 LRVVVGADDAGYEYKEALKGDLAADDrvTEVIDVGVG-ADEDTAYPHVAVAAARLIAEGK----ADRALLVCGTGLGVAI 77  Mycobacterium s...
WP_011027217   5 LRIVVGSDDAGHQYKEALKQDLRGSAlvAEVTDVGV-DADGHTAYPKVAIAAAEMVARGE----ADRALLVCGTGLGVAI 79  Streptomyces co...
WP_011731539   3 LKIVIGGDNAGFNYKEALRKDLEADDrvASVEDVGVGGVDDTTSYPNVAVAAAEKVARGE----ADRALLICGTGLGVAI 78  Mycobacterium s...
BAC73138      75 NKVKGVRAALAWSEETASLGRQHNDANVVAVGARMHTQEEATKFVETFLNTPFSGDARHIRRIDMLSAYETTGD 148 Streptomyces avermiti...
AAO44494      81 AANKVKGARAALAWNECTARLARAHNNANVVAIGARMHAHDEGFRIVLAFLREPFSEDSRHIRRIDAISLYECQ 154 Tropheryma whipplei s...
AIJ15825      75 AANKVKGVRAALAWSEETASLGRQHNNANVVAVGARMHTQEEATKFVETFLGTPFSGDERHIRRIDMLTSYETT 148 Streptomyces lividans...
WP_006768321  75 AANKVKGARCALAWSVETARLAREHNNANLIGIGGRMHSTEEALEIVDAFLDQEWSNAERHQRRIDILSDYERT 148 Corynebacterium effic...
WP_011728942  78 SANKVPGIRAVTAHDSFSVERSVLSNNAQVLCFGQRVVGLELARRLAREWLGYEFDPTSKSAEKVQAICGYEPA 151 Mycobacterium smegmatis
WP_011027217  80 AANKVRGIRAVTAHDSFSVERAILSNNAQVLTFGQRVVGLELARRLAAEWLTYRFDENSASAAKVQLMSDYETa 153 Streptomyces coelicolor
WP_011731539  79 AANKVKGIRAVTAHDVYSVQRSVLSNNAQVLCMGERVVGLELARALVKEWLGLEFDPQSASAAKVNDICAYEGA 152 Mycobacterium smegmatis
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