Conserved Protein Domain Family
MarC

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pfam01914: MarC 
MarC family integral membrane protein
Integral membrane protein family that includes the protein MarC. MarC was thought to be a multiple antibiotic resistance protein. Nevertheless, a study has shown that MarC is not involved in multiple antibiotic resistance. The function of this family is unclear.
Statistics
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PSSM-Id: 280149
Aligned: 10 rows
Threshold Bit Score: 163.994
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q32G29   5 FKAIGLGLVVLLPLANPLTTVALFLGLAGNMNSAERNRQSLMASVYVFAIMMVAYYAGQLVMDTFGISIPGLRIAGGLIV 84  Shigella dysenteriae ...
O32244   3 FSFIVHVFISLFAVSNPIGNVPIFLTLTEGYTAAERKAIARKAAILSFFILAAFLVFGHLIFKLFDINIHALRVAGGIFI 82  Bacillus subtilis sub...
O66819  10 GVLFVKAFLSLLAIMNPFSSVPVVISLMNEYSKEEIRVIALKASVYAFFILTFFLISGDLLFRFMGITLPAFKVGGGILL 89  Aquifex aeolicus VF5
P25743   8 FPVYFKFFIGLFALVNPVGIIPVFISMTSYQTAAARNKTNLTANLSVAIILWISLFLGDTILQLFGISIDSFRIAGGILV 87  Escherichia coli K-12
O28169   7 LSFFFASFTTLFIIIDPPGNLPIFIALTERFSDEYREKISKRATIIAFLILFITMVTGGKILDYFGVSISSLKIAGGILL 86  Archaeoglobus fulgidu...
Q59071   3 LQYFILAFSSIFSILNPFGAVPVFITLTESYPKKERDLVAKKTVIYALAILLAFALFGEWILKFFGISLDAFKIAGGILL 82  Methanocaldococcus ja...
O84860   2 LHSLFRLTLLFYALFNALGSLPVFIALLKNFSFKKQQHIILRESIFALLLLLLFVTFGRGFFRLLGIILPAFQFTGSLLL 81  Chlamydia trachomatis...
O83953  83 WTHIWSTAFTLLFIIDPIGNIPVVLSVLRTVPAERHTRIIFRELLLGLVLMLSFLFCGKVFLSLFQLETGVMKMAGSVIL 162 Treponema pallidum
Q32AV1   1 MNEIISAAVLLILIMDPLGNLPIFMSVLKHTEPKRRRAIMVRELLIALLVMLVFLFAGEKILAFLSLRAETVSISGGIIL 80  Shigella dysenteriae ...
Q58382  20 LNFYIYGFVSLFITIDPIGLIPIVHSLTYPYPKEQRIRIIKKAIISSTVVLLLFALFGNYIFGYFGITIDAFRVAGGILL 99  Methanocaldococcus ja...
Q32G29  85 AFIGFRMLFPQQKAidspEAKSKSEELEDEPSANIAFVPLAMPSTAGPGTIAMIISSASTVRQsstfadWVLMVAPPLIF 164 Shigella dysenteriae ...
O32244  83 FGIAYNLLNAKESHv---QSLHHDEHKESKEKADISVTPLSIPIIAGPGTIATVMSLSAGHSG------IGHYAAVMIGI 153 Bacillus subtilis sub...
O66819  90 FLIALNLVQGEVTK----EKGKAHEIEAALRRDNIALIPLAMPLLAGPGSITTVLVLRGYLNT------LEGKVALFCAI 159 Aquifex aeolicus VF5
P25743  88 VTIAMSMISGKLGE----DKQNKQEKSETAVRESIGVVPLALPLMAGPGAISSTIVWGTRYHS------ISYLFGFFVAI 157 Escherichia coli K-12
O28169  87 FISSVDILLGGTRR-----EAYKRRAEESIDVDSIAVFPLALPLYTGPGAITAGIVLYSQAGD------VVMKLLVVLSA 155 Archaeoglobus fulgidu...
Q59071  83 LLISLDMVRGQQE-----AKIHRKEIEAAYEIDEIALMPLATPLLAGPGSITACMVAMAEASD------IGDKFLVILAI 151 Methanocaldococcus ja...
O84860  82 GSIAIDMMKALPP------QTETLERDK----DEPIFFPLAFPVITGPAMITSTLGHMEEGIFp--------KKIVLGAI 143 Chlamydia trachomatis...
O83953 163 FLVGIKMVFPDQH-------ALPSTTE-----EEPFIVPIATPMIAGPSAFTTLVIMGETKGT--------SRLATCAAL 222 Treponema pallidum
Q32AV1  81 FLIAIKMIFPSASG------NSSGLPA----GEEPFIVPLAIPLVAGPTILATLMLLSHQYPN--------QMGHLVIAL 142 Shigella dysenteriae ...
Q58382 100 FKIAWDMLHAEIPK----TKHKPDERLDLEDIDSIVYVPLAIPLISGPGAITTTMILISKTQS------ILEKGVVVLSI 169 Methanocaldococcus ja...
Q32G29 165 FLVAVILWGSLRSSGAIMRLVGKGGIEAISRLMGFLLVCMGVQFIINGILEII 217 Shigella dysenteriae Sd197
O32244 154 AAVIALTFLFFHYSAFISSKLGKTEMNVITRLMGLILAVVAVGMIGAGLKGMF 206 Bacillus subtilis subsp. subtilis str. 168
O66819 160 FLSSFTAFVVYSLSTFFYRVLGRTGINLITRISGILLLAISVQFVVDGLKNLL 212 Aquifex aeolicus VF5
P25743 158 ALFALCCWGLFRMAPWLVRVLRQTGINVITRIMGLLLMALGIEFIVTGIKGIF 210 Escherichia coli K-12
O28169 156 ALVYSIVRLSHIYSAPIIRLLGRSGADIAARILAIFLAAIAVEFVFDGLAEKL 208 Archaeoglobus fulgidus DSM 4304
Q59071 152 LLSLGITYLTLLSAESVLDRIGRLGIRILTRMMGLILTAIAVQMIVNGIRGAL 204 Methanocaldococcus jannaschii DSM 2661
O84860 144 VLAWLFSLITLLLSSSINRLFGQMGLLALERLFGISLALMAGNLMLKALSTAF 196 Chlamydia trachomatis D/UW-3/CX
O83953 223 LVAWTLACLIMISAPCLYRLLKEKGITALERITGILLLILSIQMCVEGARGII 275 Treponema pallidum
Q32AV1 143 LLAWGGTFVILLQSSLFLRLLGEKGVNALERLMGLILVMMATQMFLDGIRMWM 195 Shigella dysenteriae Sd197
Q58382 170 LSAMLVSGIILSLTDFIIRRVNIYGINAFVRIMGLLLVAISVQIIFTGIVGLY 222 Methanocaldococcus jannaschii DSM 2661
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