Conserved Protein Domain Family
T6SS_TssG

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pfam06996: T6SS_TssG 
Type VI secretion, TssG
This is a family of Gram-negative bacterial proteins that form part of the type VI pathogenicity secretion system (T6SS), including TssG. TssG is homologs to phage tail proteins and is required for proper assembly of the Hcp tube in bacteria.One other member in this family, SciB (Q93IT4) from Salmonella enterica, is thought to be involved in virulence.
Statistics
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PSSM-Id: 429237
Aligned: 125 rows
Threshold Bit Score: 173.941
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_013628079       13 HLFQAVRLIqlqtlrenepqRRapQLGSDTSPD-NEPLLFAAVAKARFAGTEIESIgmes-------------------- 71  Rubinispha...
jgi:Marme_0778     15 NFAQATRILtslse------------------skgmeLSLQSDPMPHGAPTDIMSI------------------------ 52 
Q74G20             24 SFAQAVRLLrl--------lAAaqGREGACPCG----VRVRPELSLSFPVADVARI------------------------ 67  Geobacter ...
Q39QE7             24 SFLQVLRILel--------lGErdGTKRP--------VEVIPRLSLGFPAADVAGV------------------------ 63  Geobacter ...
WP_014450433       27 SFTQVIRLLrl--------vLKktDDRFAPEDFwER-IRIRPALALGFPHMDIDTIkwga-------------------- 77  Leptospiri...
Q63K64             16 AYFQAIRLLrr--------iARerRGDAAGRPDaPLPIHTRPNLSLSFPDTDVERI------------------------ 63  Burkholder...
CAP42793           28 AFFQALRLLrl--------rSAdaQAFSQD-------VRVRPSATLSFPDRDIEEI------------------------ 68 
zhongguo:PT7_2336  26 AFFQALRLLrl--------rLGeeAFERS--------VRVRPALNLSFPESDIDSI------------------------ 65 
WP_011768456       14 SFIEVYKLLce-------laLSnkLNPLHa-------IRIRPVLGLQHARTQVVSVt----------------------- 56  Psychromon...
CBL44789           24 SYLQAYRLLaq-------alSEqgNNPETA-------LRLRPALSLALPRAAIQQIstysaessvhkssveqssaeersv 89 
WP_013628079       72 ----------------------vggRSRQRGRYKLETSAIGLTGPSGALPRHYTSLLLMRQKKHDYAMARFFDLFNHRVT 129 Rubinispha...
jgi:Marme_0778     53 --------------------------QQNGKELRVKLGLEALSGCKGVIPDYLYAELLNSLHQDDEALQRFLDVFNQRYY 106
Q74G20             68 --------------------------ERQSDGYRITARFLGLYGPSSPLPTFYTEELIDEEREDGSASRDFLDVLSHRIF 121 Geobacter ...
Q39QE7             64 --------------------------ERVGDGYRVIATFLGLYGQATPLPAFYTEELLDEEATDSSAGRDFLDIVNRHIY 117 Geobacter ...
WP_014450433       78 ----------------------------egktALLDVNFFGLYGVSSPLPTFYTEDLIDYQNNDNTAPRDFLDIIHGALY 129 Leptospiri...
Q63K64             64 -------------------------DKADDGGYRVVANFFGLYGVSSPLPTFYTEDLIDEAFRGRHAARGFLDVLHRALY 118 Burkholder...
CAP42793           69 -------------------------RLDEIGKYRITANFFGLYGVTSPLPTFYTEDLIEEQLQGGSTARDFIDILHAALY 123
zhongguo:PT7_2336  66 --------------------------VREDDMLRITANFFGLYGVTSPLPTFYTEDLIDEQLAGTTNSRDFLDILHAALY 119
WP_011768456       57 -------------------------KQDQPSLYYLNVNLPGLYGNGSPLPKFFTEELIQASHKDQNQTRLFLDIIHQRLY 111 Psychromon...
CBL44789           90 eersaenaretpsenksdeysqsqaHNPKTSRYEIQANFLGLYGASSPLPNFYTEDLITGEQEDQLQARQLLDIFHQRAY 169
WP_013628079      130 ALFYRAWGKHRLPICYESAavn-------prVTDTPTDLLNCLVGqgvpqlrgraQYPDQT---LLMFAGLFSSVRRSAA 199 Rubinispha...
jgi:Marme_0778    107 ELVAYVESTASVL--LREErevaigralnrlTQQSALTHLFALPR----------QKQEGSdpsLIRYGLAMANKSRSLS 174
Q74G20            122 DLWVAGDAKYRLFNRVVED------------GSGDDLERLFCLAGldlaq--gqtvlPESGr--WLRYVGLLGQVPRSAL 185 Geobacter ...
Q39QE7            118 GIFANVARKYRLFLQVDEQ------------RSDAVTERLHALGGygeet--lraqLPDPRs--LLRYTGLFAQHPRSAL 181 Geobacter ...
WP_014450433      130 PLLYDSWKKHRLSLRAYED------------EEESVLEWFHTFTGlsdsl----fregdPLyatTLRYAGLLTQHPRSAK 193 Leptospiri...
Q63K64            119 PLLFDAWLKHRLALRIVEE------------RDEHALRPLYALAGvdariard----aglhehaLLRYVGLLSQRPRSAA 182 Burkholder...
CAP42793          124 PLLFRAWEKNRTWLAVAER------------RDANRLDHLYALVGmggga-----aarrpGvrrLLPHAGNFNQFPRSAL 186
zhongguo:PT7_2336 120 PMLFKAWEKNRIWLAVVEQ------------QDGARLNQLMALLGlhrdt----gtaasSNlraLLPHAGNFNQYPRSAL 183
WP_011768456      112 QLLYAANTQQSPH--YLDQ------------GRKNVYQFMLAMIGfkea--swlkDFPDQAf--ILRNINIIRHQKSTVV 173 Psychromon...
CBL44789          170 HLYAAALQKYRPIYELTSP------------KQSHFRQLLWALVGared--tvrrALKQPGl--ILQYAAWFTRPQKSAA 233
WP_013628079      200 GLQTILQ------TVLNA-PVEVQQFCPHWLNLEPSERTRLGSgtag-----rpahNQLGRSAICGERVFDLQSRFRITI 267 Rubinispha...
jgi:Marme_0778    175 GLKRLLC------DYFSL-DITPRAIASRLYRISPAFQTRIGTrlg--------qnHKLGHGVLLGNKGAQAYKTLEVCI 239
Q74G20            186 GLRTMVA------DALGV-PVEVIPCQHRQVSIPPGQRLAVGIa-----------aSSLGIDTVVGTNLDDRLGMFRLCL 247 Geobacter ...
Q39QE7            182 GLRTLLT------DALDA-PVEVISAVPRIVTVPPEERSRLGTi------------GTLGEDAFVGSEIPDRSGMFRIEV 242 Geobacter ...
WP_014450433      194 ALESILS------DVLGQvPVTVEQCPEKTVPIPKDQLLILGKs------------LRLGEETVLGETLTDRINQIRIRV 255 Leptospiri...
Q63K64            183 GLRALLA------DAFAPaTVDIEPCVPQWLPIPDDQRTRVGTr-----------aRRLGADARVGARMRDDGARLRIVL 245 Burkholder...
CAP42793          187 GLESLAA------GLLGAlAVEVEPCVAEVVAIPAPARCLLSEq-----------aCELGENAMLGSQIADRAGGLIMHI 249
zhongguo:PT7_2336 184 GLQALVS------GLLDGlNVWVEPCVPRTVSIPFADRTCLGKq-----------aCSLGNEALLGSQVAERTGQAYIHA 246
WP_011768456      174 GLQKLLQ------NLFKKaQVSIEQCVNRDVSIAEGQKLALNQq-----------aNQISFSAVLGGKMQDIQSKIIVSI 236 Psychromon...
CBL44789          234 GLHAILSawltdlNADQYtPIEVIQCEPQRLSIPTGNLLALGTgntagfgnaagtgKALGIDTVLGTSIIDYSGKLLVRL 313
WP_013628079      268 QTRDYREFLSFLP-EHTKLTC-VSELTRRFVGMEFDFDVQVVVPGKDIPvarlgTAAmqttgtnkrveqSEPPRLGRNAW 345 Rubinispha...
jgi:Marme_0778    240 TPRSKKEYLGLLN-NRHFSNA-LQTLALSYLRESVTTKIYLYVKREYID-----APVlssga---lssgHHAFRLGETNC 309
Q74G20            248 GPLSREQFADLLP-GAPGRST-LDLIVELYLDAPLAWDVELTLAPGETP-----EARlg---------aCRGARVGWDTW 311 Geobacter ...
Q39QE7            243 GPLRRDRFAELLP-GTPERKR-LDLLVALYITDPLAYEIELILAPGEAP-----PAMl-----------GSGIRLGWDVW 304 Geobacter ...
WP_014450433      256 GPVENDGFDRLLP-GNEDLEK-VAFWYRFYLIEPVMADIEIILSDQSPR-----PIClg---------dRVRTRLGLDSW 319 Leptospiri...
Q63K64            246 GDVPGPLFRALMP-GGDAFAR-LRLLVRLYLTQPFAVDVVVRVRARDAA-----PARcg---------rRAWSRVGLDAW 309 Burkholder...
CAP42793          250 GPIPAGRLQELLP-GAALHER-LVRAIALYLRVPLRCVLGLRVEPEQRR-----GASl----------gEGWCQLGLDTW 312
zhongguo:PT7_2336 247 GPMPAVLFERLLP-GKDLHAR-VTQAISHYVQGPISCVLGLRVEPAQRV-----PAAl----------gGGWNSLGLNTW 309
WP_011768456      237 SPLSAKEYKQWCL-TPEYWDA-LQNMIKYFIGQPLLVDLQIDVVADTKF-----NLSlv---------pENEFSLGRNAW 300 Psychromon...
CBL44789          314 GPLSTTTYRQLVPeGHPCHEAgVGLLIRTYIGPSLNCDLEFLVTPTPST-----PITlql-------gePTTNPLGLGSW 381
WP_013628079      346 LR 347 Rubinisphaera brasiliensis
jgi:Marme_0778    310 LA 311
Q74G20            312 LG 313 Geobacter sulfurreducens
Q39QE7            305 MT 306 Geobacter metallireducens GS-15
WP_014450433      320 LE 321 Leptospirillum ferrooxidans
Q63K64            310 LG 311 Burkholderia pseudomallei
CAP42793          313 LP 314
zhongguo:PT7_2336 310 LP 311
WP_011768456      301 LK 302 Psychromonas ingrahamii
CBL44789          382 LG 383
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