Conserved Protein Domain Family
FIST

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COG4398: FIST 
Small ligand-binding sensory domain FIST [Signal transduction mechanisms]
Statistics
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PSSM-Id: 443524
Aligned: 97 rows
Threshold Bit Score: 252.827
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_009519847   4 FPQAHATHPQWRMAAAMVVAQLRAQMAlpdhahQPSLGLLYITDHFADDAQAVLECVSAELpEVTDWAGTVGVGVSASNV 83 
APR87310       2 AARSFSTTINSADALARSLAAARAEVT------SPAGGLLFVSGALTQEIGRVAEQVRATW-RNIPVCIVPGAGVLSERG 74 
WP_012536490   7 FPYGHARGAGWREALSSALEMAGPRv------rGGTLGFLYVTDSFESDLPDILSAVREQT-GVPHWTGCVGAGICATAQ 79 
WP_012239559   6 MARSFSATCGP-DGLLQHLADLRSAVP------SPSGGVVFVSGQLAQRASGVAELVRSAW-RGVPACVVPAAGVLSERG 77 
WP_007088750   5 FHAAHASGENWAAVATELADQLQTQpl-----pQQALAFLYVSEALAADLGSILTFLRSRL-SLEHWVGTVGIGVCGSGR 78 
WP_015260373   7 FRAAAATASEPAVLARSLADALALPap----dsGTRIGLLYVSDSMARHGTELLAALRDAT-GVHQWVGAAGVALIANRR 81 
WP_062152353   4 FQIGHASATQWQEAMESCLAQMDLn-------kPANLGFLYLTDKFAESVYDILSHLKHRT-QIEHWVGTTGIGICCTGQ 75 
WP_070079599   4 FALAHTTGIEPEQLIADCARQLGPLp------eSASLGILYLTDALAPRLDELVEGLREVT-GVPHWVGTVGVAISVTGH 76 
WP_078121038   4 FSSAHVTGADWQSVCAGVLDRIDGd-------nAGDLAFIYLSEDLAADTDRIIDELREQS-GITHWVGCVGMGLCSNGR 75 
WP_087447549   5 FAWAHSSLGQWSEAIQDCVQQLSPVr------sAANLGFVYVTDLYANRLTEMLAQLREQT-GIAEWVGSVGIGVCATGH 77 
WP_009519847  84 EYFDEPALSVMLCDlsPDQYRVFSGvaplsasgraE---------GGEGFVAHTALVHadAGTPEVGELIAEMADRTGSG 154
APR87310      75 EIEGASAAAGLLWS--GGRVSPLAIg--------ePpsalrdaiaGVTSGRPATVLIF--PRSDFGPDMLEGIDAVAPGT 142
WP_012536490  80 EYLDEPALAFMVTDfpETEFRLFAGmgp-----yrTgksw----ptgPGRPPYFAIVHgdSQTPDLPDLVRDFAGQMGSG 150
WP_012239559  78 EIEGDTGASGVLWS--GGQVTPFALper----aeePsrllrealaRAVGQRSATAILFarPGAFA-PERLEALTLSAPNA 150
WP_007088750  79 AYFGVPAASVMVAPidPNDFHIFEPlktdtdldapElqr------aidRLQPIFGLVHgdPGAPDSLATLSELA-RLGST 151
WP_015260373  82 EYYESPTAVAMVGElpQHEVRVIGPgvqsfealceRlqg------flgLDDPGRLILHadPGFTGLEDLLTRVDRET-AW 154
WP_062152353  76 EYFNSPAIVMMLGQfpENSFNIFSTtnedfddfvsThqt------wlaSKQPLFAVVHgdPRNQKIAHQITQLSERMGEG 149
WP_070079599  77 EYYDAPALCVLVGDfpPHSFRMMPLidsdpshylaLhrd------wlqREETMVALVHgdPTNPRTPQLIGALAEAVPNL 150
WP_078121038  76 ETYGETAASVLVTPfaTDDFRLMPPiehspaewlsAter------wrnQSLASVAVVHgdPSSSELPDLLVRISDGLQGG 149
WP_087447549  78 EYLDESAVVVMLGEfpADSFRVFAPvtaadqvasaLdgf------mvhGKPAHYALVHgdARNPEIPELVRLVAAGMATG 151
WP_009519847 155 YLFGGLAGSRGPtvqFAlgsagnisgqgaASGVFHGGLSGVAFGRDVGIVSRVTQGAQPIAATHVVTESEGHLVTRLDGE 234
APR87310     143 CLFGAGTVGGSAvtvTA------------TGEILRGRAVGLAIHGLATPLIEASPACRLVTPLQPVEEVTNGMILRIGDK 210
WP_012536490 151 FITGGICSSRTDgaqL-------------VDEVVHGGLSGVTFSENIAVATRLTQGCSPIGPIHHINEAHNNVISRLDDR 217
WP_012239559 151 CLFGAGTASGSAigvTS------------QGELIEGPATGLAITGFAPPLVDASPAARLLSGFHRIDEASGGVVLRAGGR 218
WP_007088750 152 YLVGGIASGERGapqI-------------ADKVVEGGLSGVLFADKTIVQVGISQACTPVGPLHRVTEGRDGIIATLDDR 218
WP_015260373 155 FCTGGVGSGQGEvvqF-------------AGEVVSGGVSGLALRGSVPLAARHTQGCSPLPRQYRLSETWRNIIVKLDDR 221
WP_062152353 150 FLVGGLTSSRQHyfqI-------------ADNITEGNLSGVMFDSNVVVTTRLTQGCATIGQRHQITESSYNVLVKLDDR 216
WP_070079599 151 FMFGGITSSQGEhrqV-------------ADLVVGGGLSGVIFGPEVGLVTAHTQGCTPIGPRHRITRSDRNLVVDLDHE 217
WP_078121038 150 FLVGGIASADKLpvqI-------------ADKAVSGGLSGVLFSGNITVNTGLSQGCSLIGDRHQIDAGQRNIIESIDGQ 216
WP_087447549 152 FATGGISSSRFQslqV-------------ADEVVYGGLSGVMFTDAVTVMTRLSQGVTPIGPRHTVTANHENILISLDGR 218
WP_009519847 235 PALDVLLRELEISLDhpehaM-SRLRQTLVGLTRPGpdgatawsd------------sahrrgafGHEVIVRHIIGLDPV 301
APR87310     211 PALDLLSSGMPELRSatqgsPqQPQPVVFVALADAE-----------------------------GDRFVVRPVRGIDPG 261
WP_012536490 218 PALDVFNDETCDILSr---dLqRAAGFIFVAMPVKNd---------------------------dRGDYMVRTLVGIDIE 267
WP_012239559 219 PALDLLSAATATLGEp-----pSAQQLILAALADPPldlpaalpgapgadrggprgdaaeaealdSVRYVLRPVRGIDPS 293
WP_007088750 219 PALEVFKSEM-ESDGn---eNsIASGRYHVALMVPGs---------------------------dTGDFVVRNLMGVDPH 267
WP_015260373 222 PALPVFREVIGDVLSr---dLrRALGYIHIGLPISGs---------------------------dTGDYRVRNIIGIDLD 271
WP_062152353 217 PALDVFNEDIGEELAn---dLnQVAGHIFAALPVQGs---------------------------dTGDYLIRNLVGIDKE 266
WP_070079599 218 PALQVMKADIGEVLAr---dLnRVGGYIFAGLPVPGs---------------------------dDDDYLIRNLVGVDQP 267
WP_078121038 217 PALDVFKEEIGEVLAr---dLrRVGGYIFVALPIAGs---------------------------dTGDYLVRNLIGIDPD 266
WP_087447549 219 PALDVLYEDIGEILAr---dLsRAAGYIFVALSIPGs---------------------------dSRDYLVRNLIGADTA 268
WP_009519847 302 RRGVAIAELAPEGSRLAFCERHAQAARADLMRVCAEVREELepeellfgaggagdvdtapkPARAIAGAVYVSCAGRGGP 381
APR87310     262 RRGVLVGPEVKPGVRVAFAVRDASAARSKLEAAARAVSQQA--------------------MGAAPRFAIYLSCAGRGQG 321
WP_012536490 268 RKLLAIGEYAEAGQSLMFCKRDSGTAGEDLERMLSDISRLA--------------------DGRKIRGGLYFTCVWRGQN 327
WP_012239559 294 RRGLLLGDEARPGARLAFAVRDAAIGRAGLEGIARQVSRSA--------------------LGSAPRFALYLTCAGRGQG 353
WP_007088750 268 NNLMAISGDVQVGDTIRFVRRDGVAAEQDLRRMLADLQKRL--------------------PG-KPRGALYCSCVARGPH 326
WP_015260373 272 RDLLAVGEMLSQGSNILFVRRDGQAAREDLERMLAEIRAQ---------------------SGNAIRGGVYVSCLGRGRY 330
WP_062152353 267 NKLVAIGELVNTGTPIIFAQRDSRTAREDLIKMLNNIKKGL--------------------TT-TPKGGVYYSCLGRGAN 325
WP_070079599 268 RQILAIGDYAEEGGELMFCRRDGNTARADLQRMLGDLQGRM--------------------NG-TPRGAVYVSCVGRGRY 326
WP_078121038 267 QGLLAIGDYVKPGMEIQFARRDANTARDDLQQMIEGLLQRL--------------------PS-PPRGALYHSCLGRGRN 325
WP_087447549 269 ERLVAISEIVPPLAEVLFCRRDAGAAQTDMLNMLQDLQASL--------------------PA-APRGAVYYSCLGRGES 327
WP_009519847 382 HFGGPSAELQIVRHALGDVPLVGFFAGGEI-----AHHRLYGYTGVLTVFVREA 430
APR87310     322 LYGTPDVEARILRQRFGDLPIAGMHSAFEIvpwgpGEARLALYTGVLALFRSPS 375
WP_012536490 328 LFGPDSAELRMIRDGLGDFPLVGFFANAEI-----SHDKIYGYTGVLTLFLDAP 376
WP_012239559 354 LYGTPDVEARILRQRFADLPIAGMHSSFEIapwarGQARLALYTGVLALFRAPS 407
WP_007088750 327 LFGTESREMMIIRDEIGDLPLTGFYGSGEV-----CNDRFYSYTGVLTLFI--- 372
WP_015260373 331 QFGDEGAELAIVQDALGEVPLVGFFANGEI-----FANRLYGYTGVLTLFT--- 376
WP_062152353 326 LFGENSEELKIIQSVLGDVPLVGFFANGEI-----SHQRLYGYTGVLTLFL--- 371
WP_070079599 327 QFGDDSAELKLIQEALGDVPLVGFFANGEI-----FRNRLYGFTGVLTLFL--- 372
WP_078121038 326 QFGDDSEELKLIGELLGDVPLAGFYANGEI-----SHHRLYGYTGVLTLFS--- 371
WP_087447549 328 LFGAKSAELELIQQVLGDVPLVGFFANGEI-----SHDRMYGYTGVLTLFI--- 373
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