Conserved Protein Domain Family
DEAH_box_HrpB

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TIGR01970: DEAH_box_HrpB 
ATP-dependent helicase HrpB
This model represents HrpB, one of two related but uncharacterized DEAH-box ATP-dependent helicases in many Proteobacteria, but also in a few species of other lineages. The member from Rhizobium meliloti has been designated HelO. HrpB is typically about 800 residues in length, while its paralog HrpA (TIGR01967), also uncharacterized, is about 1300 amino acids long. Related characterized eukarotic proteins are RNA helicases associated with pre-mRNA processing. [Unknown function, Enzymes of unknown specificity]
Statistics
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PSSM-Id: 273901
Aligned: 6 rows
Threshold Bit Score: 1127.17
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
P37024         4 LPVAAVLPELLTALDCAPQVLLSAPTGAGKSTWLPLQLLAHP-GINGKIILLEPRRLAARNVAQRLAELLNEKPGDTVGY 82  Escherichia col...
WP_011070959   4 LPIHSLLPSLRDAFATHAQVILEAPTGAGKSTALPLAMLDWA-EISGRILMLEPRRVAARSVAQFIASCRQQAVGQEVGF 82  Shewanella onei...
WP_000074767   4 LPIIEVMPKLLSGITNSPQLILKAAPGAGKSTYFPLQLLQAG-GFHGKIIMLEPRRLAARNIARYLAQQLGEEVGQRVGY 82  Vibrio cholerae
WP_010955397   4 LPIDAALPALRQALENRDEVVLEAPPGAGKTTRVPLALLHEPwLAGQSILMLEPRRLAARAAAERLASELGEQVGETVGY 83  Pseudomonas putida
WP_012640169  12 LPIENVLPALKAALLANNATVLVAPPGAGKTTAVPLALLDAPwVEGRKIIVLEPRRLAARAAAARMASNLGESVGDTVGF 91  Caulobacter vib...
WP_011035530   9 FPISPLLPQIRDSLAAHPRLVLEAPPGAGKTTQVPLALLDAPwLAGRSIVMLEPRRVAARSAALFMARQLGEPVGETVGY 88  Xanthomonas cam...
P37024        83 RMRAQNCVGPNTRLEVVTEGVLTRMIQRDPELSGVGLVILDEFHERSLQADLALALLLDVQQGLRDD--LKLLIMSATLD 160 Escherichia col...
WP_011070959  83 RVRGEAKVSRDTRLEIVTEGILTRMIQQDPELTGIDMIIFDEIHERHLTTDLGLALALEVQSSLRDD--LKILAMSATLS 160 Shewanella onei...
WP_000074767  83 RVRGENRVSRATQLEIVTEGIMTRMLQNDPELDGVDVLIFDEFHERSIHADTALALALEVQSALRED--LKIVVMSATLD 160 Vibrio cholerae
WP_010955397  84 RIRLDSKVGPKTRIEVVTEGILTRRLQADPALEGVGLLIFDEFHERSLDADLALALSLNGRELLRDDppLKILLMSATLE 163 Pseudomonas putida
WP_012640169  92 RVRLQSKVSARTRIEVVTEGVFTRMILDDPGLDGVAAVLFDEFHERSLDADLGLAFARDVQSVLRED--LRLLIMSATLD 169 Caulobacter vib...
WP_011035530  89 RIRFENKTSARTRIEVVTEGILTRMLQDDPMLERVGALLFDEFHERHLAGDLGLALALDVQSQVRED--LRIVAMSATLD 166 Xanthomonas cam...
P37024       161 NDRLQQMLPEAPVVISEGRSFPVERRY-LPLPAHQRFDDAVAVATAEMLRQESGS----LLLFLPGVGEIQRVQEQLASR 235 Escherichia col...
WP_011070959 161 GLALSELMPYAALLKSEGRTFPVEIIY-RAVAGQQHWLDHLSRTVLDSAASITDSgpqdILVFLPGKAEILRVAQYLAER 239 Shewanella onei...
WP_000074767 161 QQALQNLLPQASYVESQGRGFPIEIRY-QPLRSDEPLVTAMQRQIRHLLQHETGS----LLAFLPGAASINQLTEQLSD- 234 Vibrio cholerae
WP_010955397 164 GERLSRLLDDAPVVSSEGRMHPVDIRWgRPFQPGEFIEPRVVDCVLHALADQAGS----VLVFLPGQAEIRRVHQSLQEV 239 Pseudomonas putida
WP_012640169 170 GARISSLLNDAPVVESQGRMFPVDTRY-LGRDERQRLEERVGRAVERALAEESGS----ILVFLPGQGEIRRAESWLNER 244 Caulobacter vib...
WP_011035530 167 GERLASFL-DAPRLSSAGRSYPVEVAH-FPARRDEALEPQTRRAVEHALATHPGD----VLVFLPGQREIARVQAALQDA 240 Xanthomonas cam...
P37024       236 IG--SDVLLCPLYGALSLNDQRKAILPAPQGMRKVVLATNIAETSLTIEGIRLVVDCAQERVARFDPRTGLTRLITQRVS 313 Escherichia col...
WP_011070959 240 LDg-SRVAICPLYGELSAQEQDRAIKADASGRRKIVLSTNVAESSLTIEGIGLVIDSGYKRQASFNPKTGVTRLSLKRIS 318 Shewanella onei...
WP_000074767 235 LA--SEVEICPLYGQMEFAAQQRAIAPTAAGRRKVVLATNIAETSLTIEGIRIVLDSGLERSARFDLKTGITRLEQVRIA 312 Vibrio cholerae
WP_010955397 240 LGarPEILLCPLHGELDLNAQRAAIDPPAKGLRKVVLATNIAETSLTIDGVRVVIDAGLARVPRFDPGSGMTRLDTQRIS 319 Pseudomonas putida
WP_012640169 245 LRr-SDVDIAPLYGALEPAAQDRAISPAPAGRRKVVLATSIAETSLTIEGVRVVIDAGQARVPRFDPASGITRLETVRVS 323 Caulobacter vib...
WP_011035530 241 LD--PAMQLLPLHGELPVEAQSQVLQPDPQGRRRVVLATNVAESSVTLPGVRVVIDSGLAREPHYDPNSGFSRLDVTSIA 318 Xanthomonas cam...
P37024       314 QASMTQRAGRAGRLEPGISLHLIAKEQAERAAAQSEPEILQSDLSGLLMELLQWGCSDPAQMSWLDQPPVVNLLAAKRLL 393 Escherichia col...
WP_011070959 319 QASATQRAGRAGRLAAGVCIRLWGQEEHQRLLKADEPEISQADLVSMAHDCAYWGAKSFSDLLLLTAPPSVNEALAWQLL 398 Shewanella onei...
WP_000074767 313 QSSAEQRAGRAGRLEPGICVRLYSEAQLKQQPWVPEPEMLHTDLAPLALELAQWGAQ-PSDLAWLNLPPSSAFAQAQQLL 391 Vibrio cholerae
WP_010955397 320 RASATQRAGRAGRLEPGVCYRLWSEAQHDQLAAHGSAEILQADLAGLALQLARWGVT-PEQLRWLDQPPAAAYAQAQDLL 398 Pseudomonas putida
WP_012640169 324 RAAADQRRGRAGRTEPGVCYRLWDEPETRSLPAFARPEILEADLSRLALDLARWGTKDPSDLTFLDPPPAAAFAEARTLL 403 Caulobacter vib...
WP_011035530 319 QASADQRAGRAGRVASGWAYRLWPQSQ--RLEPQRRAEITQVELTGLALELAAWGSD---ALRFVDAPPGGALAAARELL 393 Xanthomonas cam...
P37024       394 QMLGALEGE-R--LSAQGQKMAALGNDPRLAAMLVSA--KNDDEAATAAKIAAILEEP--PRMGnSDLGVAFSRNQPAW- 465 Escherichia col...
WP_011070959 399 RRLDVVDGQnK--LTAHGKAAYELGCHPRLAHMLLAAksHSTELAALACLLAGILEARglPRKG-ADIMNYLHFATQGS- 474 Shewanella onei...
WP_000074767 392 QRLGLLDARtQ--ITAAGKEAHLLGVEPRIAAMLLSAdrLGESALQSALALTVLLEEP--ERQv-IDVQHSLHRWQQGR- 465 Vibrio cholerae
WP_010955397 399 ARLSAFRPGsRdtLSEHGQAMAELPAHPRIAHLLLRG--QDLGLAQMACDVAALLGERdiQRGGgADLHSRLALVSGESk 476 Pseudomonas putida
WP_012640169 404 MRVQALDAQgD--LTAHGKALADLPLPPRLAHMVARG--AASGQAREAAEIAAVLTEQg-LGGRdVDLRRRLEGLHRDR- 477 Caulobacter vib...
WP_011035530 394 QRLGGLNAEgG--ITALGRRMLALATHPRLAALLAQA--GTPARLALACDLAALLEARhpLRQGgDGLAARWRALAAFR- 468 Xanthomonas cam...
P37024       466 -----Q-------QRS--------QQLLKRLNVRG--GEADSSLIA---------PLLAGAFADRIARRRGq-DG-RYQL 512 Escherichia col...
WP_011070959 475 -----Ag------QQA--------KQWLRKLALDSkfTQADLGAIAshahhrdvgLLLALAYPDRIAKSRG--VE-GYQL 532 Shewanella onei...
WP_000074767 466 -----HpkqklliQRA--------QSLAHKLDTAFslSSVDSAWLP---------LVACLAFPDRIAQQRGqqTG-QFLL 522 Vibrio cholerae
WP_010955397 477 aarggQgg----vQRA--------RQLARQYRGLLr-GKVGAPVADpdhp-rwlgALLALAYPDRVAQQRRa-GGaEYRL 541 Pseudomonas putida
WP_012640169 478 -----Spr----gRDA--------MALVERWSRAAgrS---SGAKPle-----igLLLAEAYPERVAKARGk-PG-EFQL 530 Caulobacter vib...
WP_011035530 469 -----Qgr---tgADAnrgalaaiDAAAKQWRRRLrcDATPPTSVEaha----lgDLLSHAFPDRIAARHPtdPL-RYLL 535 Xanthomonas cam...
P37024       513 ANGMGAMLDANDALSRHEWLIAPLLLQGSASPDARILLALLVDIDELVQRCPQLVQQSDTVEWDDAQGTLKAWRRLQIGQ 592 Escherichia col...
WP_011070959 533 ANGTGVVLSAEDALAQTPWLVVADFQETEGKTAGRVYLACPLQPSLFDHELADLVDTHEQCGWDETKGRAVAERQAKVGQ 612 Shewanella onei...
WP_000074767 523 ANGHGAWLAVEDRLSAADYLVALDLMRGQT-QASQIFSALELDIHALERVLPALISRVEQVDWDEKAGRLSAEAQWRIDQ 601 Vibrio cholerae
WP_010955397 542 ANGRAALFGEVDALMKCPWLVIADLGSRQGQREERIYLAAEFDPALLEGVLAEQVERVDILDWDEREQVLRAERQVKVGE 621 Pseudomonas putida
WP_012640169 531 AGGRGVYLEPTDPLAREAWLAVGELGGG--DSRDRILLAAAVDEAQLRETFADRLVAEDRL--ETTGGKVRAKRLLRLGK 606 Caulobacter vib...
WP_011035530 536 ANGRSARLFDHSDLRGEPWLVASELRYE--AKDALLLRAAPVDEGYLRQSVPERFVQQDVVQWDADKRALVARRQSSFDR 613 Xanthomonas cam...
P37024       593 LTVKVQPLAKPSEDELHQAMLNGIRDKGLSVLNWTAEAEQLRLRLLCAAKWLPEYD----WPAVDDESLLAALETWLLPH 668 Escherichia col...
WP_011070959 613 ILLKSETIANPNRAQIVAALVNYIRQQGLQILNWNANLEQFQARLHLARSLDPTAD----WPDMSDAALLADLETWLAPY 688 Shewanella onei...
WP_000074767 602 LVLRREKLPEPDKQKMTQALLSYVRRKGLTVLQWSEDASEWLARARCAAEWLPEEA----WPALDDETLLARLELWLEPY 677 Vibrio cholerae
WP_010955397 622 LVLSREPLPGLDDEARTRALLGLVRRKGLNLLTWTPELRQWQARVALLRQLDLQKDghseWPDLGDEALLASLEDWLQPY 701 Pseudomonas putida
WP_012640169 607 LVLEERLIENPDPAMIAGALLDQVRADGLSALRLGERGRALLDRVAFLRDVDGEA-----WPDLSESALIERLDEWLEPL 681 Caulobacter vib...
WP_011035530 614 IVLDSRPAGRVDPAQAAAALTEAVRQLGLDALPWTEGLRQWRARVVSLRAWMPELG----LPDLSDTALLASLDHWLRPA 689 Xanthomonas cam...
P37024       669 MTGVHSLRGLKSLDIYQALRGLLDWGMQQRLDSELPAHYTVPTGSRIAIRYHEDN-----PPALAVRMQEMFGEATNPTI 743 Escherichia col...
WP_011070959 689 LENVNNLPQLQKLDCFSLVMNQLSWSQQQALDALLPTSWPLATGTFAPIVYETSG-----RALLRVRLQETFGMADSPLL 763 Shewanella onei...
WP_000074767 678 LAGVTSVKGLQSVSVLQALKHYLGWELSQQLDEWLPTHHLLPTGNHKKIRYQLGM-----EPTLSVRMQEVFGEQSSPRV 752 Vibrio cholerae
WP_010955397 702 LSKVSRLSHFAALDLPSMLRNLLPWPLPQRLEEQAPAHLAVPSGSNIRLDYSE-T-----PPILAVRLQELFGLADTPRI 775 Pseudomonas putida
WP_012640169 682 LAGRSSLSSLDEGTLYDALKTLVPWDLQRKMDALLPARFEAPTGNSFAIDYSAEG-----GPRVEVRVGELYGLSEHPSV 756 Caulobacter vib...
WP_011035530 690 FAGKTRLDALDEASLGDALKAALPWERRQAIDRHAPTRISVPSGMERAITYALDHdqqplPPVLAVKLQELFGLAETPRV 769 Xanthomonas cam...
P37024       744 AQGRVPLVLELLSPAQRPLQITRDLSDFWKGAYREVQKEMKGRYPKHVWPDDPANTAPTRRTKKYS 809 Escherichia coli K-12
WP_011070959 764 AQGKLKVTMELLSPAQRPLALTADLASFWQGPYVEVKKEMRGRYPKHLWPDDPANTLPTKFTKKKT 829 Shewanella oneidensis
WP_000074767 753 AKGTRAVVMELLSPAQRPLQVTRDLASFWAGAYKEVQKEMKGRYPKHVWPDDPANHVATSKTKRQL 818 Vibrio cholerae
WP_010955397 776 ANGRQQVKLHLLSPARRPVQVTQDLASFWRTTYAEVKKDLKGRYPKHYWPDDPLVAEATARAKPRG 841 Pseudomonas putida
WP_012640169 757 AGGKVPLTLSLLSPAHRPIQITKDLPGFWKGSWREVKVEMKGRYPRHVWPDDPAAAAPVTRAKPRG 822 Caulobacter vibrioides
WP_011035530 770 ADGRIPLTLHLLSPGGRPLQVTQDLKSCWATTYPDVKKEMKGRYPRHPWPDDPWTANATHRAKPRG 835 Xanthomonas campestris
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