6KXU


Conserved Protein Domain Family
Copine

?
pfam07002: Copine 
Copine
This family represents a conserved region approximately 220 residues long within eukaryotic copines. Copines are Ca(2+)-dependent phospholipid-binding proteins that are thought to be involved in membrane-trafficking, and may also be involved in cell division and growth.
Statistics
?
PSSM-Id: 462064
Aligned: 15 rows
Threshold Bit Score: 277.679
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
?
Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
6KXU_B  316 SLHYIDPSgRLNAYQRAIMDVGEVLQFY---DSDKRFPAWGFGA--R-PID-APVSHCFNLNGSSS---YSEVDGIQGIM 385  thale cress
Q9UBL6  401 SLHYINPY-QPNEYLKALVSVGEICQDY---DSDKRFSALGFGA--RiPPK-YEVSHDFAINFNPE---DDECEGIQGVV 470  human
O95741  325 SLHCLSPR-QPNHYLQALRAVGGICQDY---DSDKRFPAFGFGA--RiPPN-FEVSHDFAINFDPE---NPECEEISGVI 394  human
Q9HCH3  347 SLHYMSPY-QLNAYALALTAVGEIIQHY---DSDKMFPALGFGA--KlPPD-GRVSHEFPLNGNQE---NPSCCGIDGIL 416  human
Q9XUB9  357 SLHFMSAD-RPNQYELALRSVLSICQHY---NSSKTFEAFGFGA--KlPNQ-SSVSAIFPLDLQRG---TSEVVGITGVM 426  Caenorhabditis elegans
Q22422  349 SLHYMATG-IPNQYEIALRSVLTICQHY---NSSKTFEAYGFGA--KlPNH-QTVSAVFPLDLNRQ---SSSVVGINGVM 418  Caenorhabditis elegans
Q17559  295 SLHYIHPH-QPSPYLEALLQTVPPLLAYlpnPQNPHIGALGFGAkvQvPGGaLQLSHCFCLNGTPT---DPRVEGLGGLL 370  Caenorhabditis elegans
Q09221 7498 PLHTIDPA-EMNPYQQVIQIVGKTLSSF---DADGQIPAYGFGD--------EEFTDHGIFNIAERydlEKDCNGFEEVL 7565 Caenorhabditis elegans
Q8RX26   60 SLHAIG-K-RQNPYEKAISIIGRTLSPF---DEDDLIPCFGFGD--------VTTRDQYVFSFYPE---NKSCDGLENAV 123  thale cress
Q9LY87  145 SLHFIG-S-SPNPYEQAITIIGRTLAAF---DEDNLIPCYGFGD--------ASTHDQDVFSFNSE---DRFCNGFEEVL 208  thale cress
6KXU_B  386 TSYTSALFNVSLAGPTLFGPVINAAAMIASAs-LAQGSRKYYVLLIITDGVIT------------DLQETKDALVSASDL 452  thale cress
Q9UBL6  471 EAYQNCLPRVQLYGPTNVAPIISKVARVAAAeeSTGKASQYYILLILTDGVVT------------DMADTREAIVRASRL 538  human
O95741  395 ASYRRCLPQIQLYGPTNVAPIINRVAEPAQReqSTGQATKYSVLLVLTDGVVS------------DMAETRTAIVRASRL 462  human
Q9HCH3  417 EAYHRSLRTVQLYGPTNFAPVVTHVARNAAA---VQDGSQYSVLLIITDGVIS------------DMAQTKEAIVNAAKL 481  human
Q9XUB9  427 TAYRHALSNVQLYGPTNFAPIIENVARKAQN--MIHDSARYQILLIITDGIIS------------DMHATIRSIISASGL 492  Caenorhabditis elegans
Q22422  419 NAYRHALQNVTLYGPTNFSPIIVEVANKAQK--MMKTTARYQILLIITDGIIS------------DMYATINTVINASGL 484  Caenorhabditis elegans
Q17559  371 SAYRTAVMGLQPFAPTDFSEVIYFMSKFAKAe-SRRHVGLYFVLIIYSDGGPAna---------lNMKRSIDAIVDASPH 440  Caenorhabditis elegans
Q09221 7566 RVYNEVTPTIEMSGPTNFVPLIDRAIEICKE------KHSYHILVIVADGQVT------------NEKINQKAIAAASHY 7627 Caenorhabditis elegans
Q8RX26  124 KRYREIVPHLKLSGPTSFAPVIDAAINIVEQ-----NNMQYHVLVIIADGQVTrnpdvplgrlspQEEATMNSIMAASHY 198  thale cress
Q9LY87  209 SRYKEIVPQLKLAGPTSFAPIIDMAMTIVEQ-----SGGQYHVLVIIADGQVTrsvdtengqlspQEQKTVDAIVQASKL 283  thale cress
6KXU_B  453 PLSILIVGVG-GADFKEMEILDADKgeRLESSSGRLASR--DIVQFVALRDVQY-----------GEISVVQALLAELPS 518  thale cress
Q9UBL6  539 PMSIIIVGVG-NADFTDMQVLDGDDg-VLRSPRGEPALR--DIVQFVPFRELKNa----------SPAALAKCVLAEVPK 604  human
O95741  463 PMSIIIVGVG-NADFSDMRLLDGDDg-PLRCPRGVPAAR--DIVQFVPFRDFKDa----------APSALAKCVLAEVPR 528  human
Q9HCH3  482 PMSIIIVGVG-QAEFDAMVELDGDD--VRISSRGKLAER--DIVQFVPFRDYVDrtgn----hvlSMARLARDVLAEIPD 552  human
Q9XUB9  493 PLSIIIIGVG-NEDFEKMHELDSDD--ALLQQDSRIAQR--DIVQFVTMREFLNngqglyldpdvIQENLAREVLYEVPA 567  Caenorhabditis elegans
Q22422  485 PLSIIIIGVG-NEDFERMHELDSDD--ALLQQDSRIAER--DIVQFVTMRDFLGnqsggylntdtIMENLAREVLYEVPD 559  Caenorhabditis elegans
Q17559  441 PMSIIGVGMGqDRDHSPMRNLEKL---TLKHSDGRLLVR--QNYSYVDPSDLES-----------------SDVLAMIPI 498  Caenorhabditis elegans
Q09221 7628 PLSIIMVGVG-DGPWNMMGRFDDN-----------IPKRlfDNFHFVDFHKVMFna-------pnADASFALNALMEIPD 7688 Caenorhabditis elegans
Q8RX26  199 PLSIVLVGVG-DGPWDTMKQFDDN-----------IPHRefDNFQFVNFTKIMSehkd----aakKEAAFALAALMEIPF 262  thale cress
Q9LY87  284 PLSIVLVGVG-DGPWDMMREFDDN-----------IPARafDNFQFVNFTEIMAknka----qslKETEFALSALMEIPQ 347  thale cress
6KXU_B  519 QFLTYMRIRN 528  thale cress
Q9UBL6  605 QVVEYYSHRG 614  human
O95741  529 QVVEYYASQG 538  human
Q9HCH3  553 QLVSYMKAQG 562  human
Q9XUB9  568 QLTGYMKQRG 577  Caenorhabditis elegans
Q22422  560 QLTGYMKRRG 569  Caenorhabditis elegans
Q17559  499 QMAQWKRMFH 508  Caenorhabditis elegans
Q09221 7689 QYKAIKELGL 7698 Caenorhabditis elegans
Q8RX26  263 QYKATLSLNR 272  thale cress
Q9LY87  348 QYKATIELNL 357  thale cress
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap