Conserved Protein Domain Family
COG3744

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COG3744: COG3744 
PIN domain nuclease, a component of toxin-antitoxin system (PIN domain) [Defense mechanisms]
Statistics
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PSSM-Id: 442958
Aligned: 305 rows
Threshold Bit Score: 59.0741
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
AEI47767       1 MEdsvqlssppkkvksrqshpknailqtheivdyspfgaavpavdfpyrklpkqVMLDTPTLDLLIRNPNRLSHNALRLI 80 
WP_011504829   1 MTe--------------------------------------------------aLLLDTHIALWLDSGNDRLHHSTRALI 30 
WP_011504829   1 MTe--------------------------------------------------aLLLDTHIALWLDSGNDRLHHSTRALI 30 
WP_013041632  10 APr--------------------------------------------------aVLLDTCAVIWLANGD-SIAPAALEAI 38 
WP_013654291   1 MAd--------------------------------------------------rLLLDTCAMIWLSQG-EPVADAAMAAI 29 
WP_038587688   1 MSe--------------------------------------------------sYLLDTCAVIWMTHN-ELLAARAADAV 29 
WP_019963315   1 MSe--------------------------------------------------pLLLDTCAMIWLSQG-APVSDAAMKAI 29 
WP_069052193   9 LPs--------------------------------------------------sVLLDTCAVIWLANGD-PLAQEALAAI 37 
WP_086090169   1 MSs--------------------------------------------------pLLLDTCAAIFIAEG-ETLSKPARQAL 29 
WP_099509638   1 MAp---------------------------------------------------LLLDTCAVLWIANG-EEISEDCRRAV 28 
AEI47767      81 NEC---EEGGCLSSATVLEWAHW--VQRGY---YQLEISLNTFFEQILQQWQLQLLPLPLEAYSLYTELPvvtaelktse 152
WP_011504829  31 DNCwrnGGTIFLSSVTAWEIALL--VDTGR---IELDIPVDAWIDRFLDRPGLEGVPLAHRAAARSYQLHhl-------- 97 
WP_011504829  31 DNCwrnGGTIFLSSVTAWEIALL--VDTGR---IELDIPVDAWIDRFLDRPGLEGVPLAHRAAARSYQLHhl-------- 97 
WP_013041632  39 THAa-lADGVFVSPASAWEVGLLsrVRGDKspsVAFLPDPQSWFASFMAGPAIREAPLLPEIAIASSLLPep-------- 109
WP_013654291  30 DAVeaaGEPISLSVMSAWELGLL--VATGR---IASTKPPLRWFQDFVAAADVTVEAVTADILIASSCLPap-------- 96 
WP_038587688  30 SGSkamGIPVYVSTATAWEMAML--VARGR---IHETKDAKRWYDSFRQETEVAEKSVTADLFMASCILPqp-------- 96 
WP_019963315  30 GAVdtaKHPLRLSVMSAWELGVL--VAKGR---LASTKPPLRWFEEFVDVAGIQVEEVTAGILIASSYLPep-------- 96 
WP_069052193  38 SHAa-lAEGVFVSPASAWEVGLLsrVRSGNvpaLTFLPDPQSWFARFMAGPGIKEAPLLPEIAIASSHLPdp-------- 108
WP_086090169  30 EMAfddAVPVWISPISAWEIGLL--VARGR---LRLQIAPQVWFRRLRDDLNFLLADMPPDVLIASSDLPes-------- 96 
WP_099509638  29 DEAa-pSDRILISPITAWEIGTL--VRKGR---IALSMPPEAWFDAALALPGVRLAPMPPRTLIASAFLPgm-------- 94 
AEI47767     153 kaegngkarklvHDDPYDQLIAAHAIVAKIPLVSPHGIFKNYeryGLKWAW 203
WP_011504829  98 -----------eHRDPADRLLIATAIDLRCPLVTYDERITQFg--KKRGRQ 135
WP_011504829  98 -----------eHRDPADRLLIATAIDLRCPLVTYDERITQFg--KKRGRQ 135
WP_013041632 110 -----------lHGDPADRFIIATARHHRVPVITRDGKIIEYa--SAGHVS 147
WP_013654291  97 -----------vHGDPMDRILIATAREHDLTIVTRDRAILAYg--EAGHVR 134
WP_038587688  97 -----------iHKDPIDRILIATAREHDLTIITRDRAILSYg--AAGHVR 134
WP_019963315  97 -----------vHNDPMDRILIATAREHDLTIVTRDRAILAYg--EAGHVR 134
WP_069052193 109 -----------lHGDPADRFVIATARHHQIPVITRDSKIIDYa--AQGHVK 146
WP_086090169  97 -----------tLRDPADRIIVATAREYGYRIVTRDNPILQYa--ANGHVQ 134
WP_099509638  95 -----------pPADPADRIIAATARTEGFVLVTRDRKLLSYg--NEGHVR 132
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