Conserved Protein Domain Family
PRK04036

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PRK04036: PRK04036 
DNA-directed DNA polymerase II small subunit
Links
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Statistics
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PSSM-Id: 235208
Aligned: 60 rows
Threshold Bit Score: 512.189
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
18976390    1 MDEFVKSLLKANYLI-TPSAYYLLREYYE--KGEFSIVELVKFARSRESYIItdalateFLKVKGLEPILpvetkggfvs 77 
57641837    1 --MLVEDLLKNNYLI-TPSAYYLLSDHYKkaFTLAELIKFAKNRGTF------------VVDSNLAREFLaekgiissgn 65 
212224794   1 -MGLIEDLMANNYLI-TPSAYYLLVDGYKkdFTLAELIKFAKARGTF------------VIDSTVAREFLmekgmaples 66 
13542203    6 KASLLEYFTKNGVLV-SPSALEKIIK-----YSSSSLIEDLVKNSDG------------YIDDRIVEAAL---------- 57 
16081371   31 RTSLIQYFNSNGVLI-SPEALDKLIKYSS-----SSLIEDLIKNSDG------------YIDEKYVERYV---------- 82 
20095019    6 TKQLARKVAEEYGVLlTPEALRELE--DE--DDAPEVLEKSDEVDLP------------VFTAQLIrgevdp-------- 61 
48477541    7 RESILKYFQDHGILV-SPGALNIILERSMgeLIPKMLSDDVISSGYLSESEVlrlirspKVEKNDFEVYV---------- 75 
161527514   5 LSFALNYALNKGFQI-HPNAFKILENVDV--KKLEKIIKEIVREKTKQ-KLF-------QINQDDLETYLg--------- 64 
289596289   4 RKEIVEELLKHEILV-EPEVVDYIIEKGGlnYVPS------------------------FIELHKNSSFV---------- 48 
170290998   4 EVELLRKFLRRGLNL-TPEALSCLMRMDD--------VERIVELLPRKP----------VIDYEDILPLM---------- 54 
18976390   78 tgesqkeqsyeesfgtkeeisqeikegesfis------------------------------------------------ 109
57641837   66 galdgsvlsgisvsespvkpngeavlesesdesgaiesslqegvedgvesiaepsaasvedvvvagesslasegsslede 145
212224794  67 sisssaefhphveeqtsedmaseaemlvetpgtvessavdgeilelttvaavhsadegtsistgtssesggdmsemgplg 146
13542203      --------------------------------------------------------------------------------    
16081371      --------------------------------------------------------------------------------    
20095019      --------------------------------------------------------------------------------    
48477541      --------------------------------------------------------------------------------    
161527514     --------------------------------------------------------------------------------    
289596289     --------------------------------------------------------------------------------    
170290998     --------------------------------------------------------------------------------    
18976390      --------------------------------------------------------------------------------    
57641837  146 intepelsssmddgaevvqssegdetsistgnalgsvdyggsdsesealeeassggesfistgtpedealleespegefp 225
212224794 147 ------------------------------------qeepnfsggesyistgtleespligdsesetevmeasisevade 190
13542203      --------------------------------------------------------------------------------    
16081371      --------------------------------------------------------------------------------    
20095019      --------------------------------------------------------------------------------    
48477541      --------------------------------------------------------------------------------    
161527514     --------------------------------------------------------------------------------    
289596289     --------------------------------------------------------------------------------    
170290998     --------------------------------------------------------------------------------    
18976390  110 ----tgsepleeelnsigieeiganeelvsngndnggeaivfdkygYPMVYAPEEIEVEEKEYSKYEDLTIPMNPDFNYV 185
57641837  226 dengfsdeslpvengsengygdseeyyengdngvkpkivygdygvpIAYVADETPEEEKAYSTYSDLVIAPKEGFHYRAK 305
212224794 191 tlpvegglsveeaptgndngnvpsyvsseeadngvkprivygdygvPIAYVEEVPEEEKSYSVYSDFRISPKEGFYYRAK 270
13542203      --------------------------------------------------------------------------------    
16081371   83 -----------------------------------------------------------------------------SRP 85 
20095019   62 -----------------------------------------dflegMEGDVYEILEAEESEEEHEARPRAERPSKLPPAA 100
48477541      --------------------------------------------------------------------------------    
161527514  65 ---------------------------------------------------------------------------IKDDP 69 
289596289  49 ------------------------------------------------------SISSIKPPKIENKPKEKSDMTKPEAY 74 
170290998  55 ----------------------------------------------------------------------------RAES 58 
18976390  186 EIKEDYDVVFDVRNVKLKPPKVKNgngkegeiiveaYASLFRSRLKKLRKILRENPELD--NVVDIGKLKYv--kEDETV 261
57641837  306 EIPDEWELAFDVKNVKFEVPKVKNaqskegeviiqaYSSYFKSRLKKMRRIFRENPEIG--TIVDIAKLSYv---REDDV 380
212224794 271 EIPEDYEIAFDVKDVKFTIPKAKDargkegeiiikvYADYFRSRLKKMRRILRENPEIG--SVIDIAKLSYv--rTDDDV 346
13542203   58 KPKREMNDFEVYLPEVRFNSSVED------------FRKMFVSKYEKLSRIISASSSMR--GSISIKTAKH----SQGQV 119
16081371   86 KVRNDYEVYL---PDVRFNASIED------------FRKMFVSKYEKLSKIITSSSSMR--GSISIKTAKR----SQGEV 144
20095019  101 EVDAEVEILEEARSVSAN-GSVEG------------FVAHFRDRLEKLRPLVKAKLDGE--WVKDIGELVErarrEPGNY 165
48477541   76 -------------PDIRAHSSVED------------FREMFVDRYEKIRKMIIQSSEMR--GTLTIKSAKV----SQGKV 124
161527514  70 SLENEVKVLLDPTDKITTGEGVKG------------YNALFSSRFNKLKRIISDRPEAR--MLKSLTFVKNe--rSEDDM 133
289596289  75 EYDWDFKVLID-PGNIQSSGKVDD------------FRALFLDRYKRLSKYVRRNMQMR--GATEIANM------ERGEV 133
170290998  59 DEKIEFDVILKP-DNLGISGNVEE------------FIRFIRARFDKLRPLVARWVDLEpiPIAELRNKTTr---NGDNL 122
18976390  262 TIIGLVNSKREVNKGL-IFEIEDLTGKVKVFL-PKDSEDYREAF--KVLPDAVVAFKGVYSKRg---ILYA----NKFYL 330
57641837  381 TIIGLVNEKRETRKGY-LFEIEDATGRIKVFI-GSDKEGANEAYs-TIMPDSVVAFRGTPGKG----IFFA----NRVFL 449
212224794 347 TIIGLVNSKRETAKGF-MFEVEDNTGIIKVFI-NRNNEDSKKFF--EIMPDAVVAFKGRYSGRg---IFFA----DKIYL 415
13542203  120 KVIGMVSEVSMTKNGHkRVLIEDLDDSIQVFI-LKDRGIINEVI----LEDEVIGIIGNVSSSskdpVIFA----DEIVR 190
16081371  145 KVVGMVSEVSMTKNGHkRIVIEDLDDSITAIV-MKDRGPVNEII----LEDEVIGIIGSVSQSskdpVIFV----NEIIR 215
20095019  166 CVAGVVTGLRETERAF-LLDLEDEAGKVRVVIsKPKAPKISEKVrrDVAPGMVIGVKGFVKVErg-pVMFVgdryGEVTL 243
48477541  125 KIVGIVSDISTTKNGHkKLLVEDLDDHMDVFL-LKSK----GLSneLILEDEVIGIIGSISRTgrdtVMFA----DEIIR 195
161527514 134 YVCGLVTSRNSERNVTkLV-LEDPSGSFEGIIfDT---ELQKTAd-TLLVDQFVMARVSVGKNs---GFII----KDLIF 201
289596289 134 KIIGLVDDVRYTSRGSlSFYLEDPTGRVKCIA-PQGe---------FLLNDEVIGVIGKYNEEs--nLIYV----NEIVR 197
170290998 123 FIIGMIMEKISAKDGSiRMVIEDESGTVNVVF-RRDS-RAWELAe-RTPLDSVIGVRGTYVNGk----LYG----ESILL 191
18976390  331 PDVPLyrrqKPPLEEKVYAILISDIHVGSKEFCENAFIKFLEWLNGNVETkeEEEIVSRVKYLIIAGDVVDGVGVYPGQY 410
57641837  450 PDVPKfkrsKPPLEEKVYAILLSDIHVGSNKFCEEAFIKFLEWLNGEVNSrtEEELVSRIKYIIIGGDVVDGVGIYPGQY 529
212224794 416 PDVPKfkreKPPLEEKVYAVLLSDVHVGSNKFCEKAFMRFLEWLNGDVNNraEEELVSRIKYMIIAGDVVDGIGIYPGQY 495
13542203  191 PDIPYri-lDETKHEPVFVASLSDIHIGSKTFRKNEFQDMIKWFESSDDT------SLSTKYLILSGDVVDGIGVYPGQE 263
16081371  216 PDIPYrv-iDEEKHEPVYVASISDIHVGSKTFRKNEFEAMVRWISGSDPD------ASRVKYLILSGDVVDGIGVYPDQE 288
20095019  244 PGEGDhksrVPAVEDDVKAVFIGDVHIGSKKFREDLFRRFLEWLNDPNDP-----VASRVKYVIVTGDVVDGIGIYPGQR 318
48477541  196 PDIPRkm-iYEDKKEPVYIASISDIHVGSRTFRKNDFQKLISWIKSSRNE------AQYLKYLILSGDVVDGIGVYPGQE 268
161527514 202 PDIPdq--aTNKSESEAYAVFLSDLHIGSKYFMEEELTEFFSWISSPDPT------AKKIRFILIGGDMVDGVGIYPNQN 273
289596289 198 PGFRKin-kGRVTEEQIGAVIISDVHIGSKMFLQKNWEKFLDWLKSGKNG------AEIVKYLIIGGDLVDGIGIYPNQE 270
170290998 192 PDVKsd--eVSEGRHEGRAVMISDVHVGSRYFNEWAFEKFVRWLRSED--------ARDVRYLIICGDLVDGIGVYPNQE 261
18976390  411 ADLTIPDIFDQYEALANLLSHVPKHITMFIAPGNHDAARQAIPQPEFYKEYaKPIYKL-KNAVIISNPAVIRLH-GRDFL 488
57641837  530 NELAIPDIFDQYEALANLLKQVPDHITMFIGPGNHDAARTALPQPGFYEEYaKPLYKL-KNAVIISNPAVIRLH-GRDFL 607
212224794 496 NELAIPDIFDQYEALANLLSNVPDHITMFIGPGNHDAARTALPQPGFYEEYaRPLLKL-KNAVIISNPAVVKLH-GRDFL 573
13542203  264 NDLELLNPLDQYEALASFVSQIPEDITVFIMPGNHDTVRLSEPQPVFPEKI-RKMFPS--NAVFLPNPYNLKLE-GKNVL 339
16081371  289 NDLEILNPLEQYANLAEYLVDVPEDVKVFVMPGNHDTVRLSEPQPVFPGKI-RDLFEP--NVAFLPNPYNLKLE-GKNVL 364
20095019  319 EELEIADIDEQYQRFAEYLELLPDWVEVIVIPGNHDALRQALPQPSLSSSDpAQPLTElDGVHLPSNPALVRIHgELDVL 398
48477541  269 NDIEILNPFEQYEKLAEYLNELPDDIDIFLTPGNHDNVRLAEPQPVFSKKI-SDFFNK--NVHLIPNPFNIEIN-GKNVL 344
161527514 274 KELVCQTIEEQLKKVESLIDQIPKNIKIIIMPGNHDPGRRALPQPAIPKKYnSGLWDR-ENVIMVGNPAVVSLN-GVKVM 351
289596289 271 EELEILDIYKQYEALASYIQELPDYIKVIMIPGNHDLVRNAEPQPPLPSDV-RALFNG--NVEFLSNPTLFSLH-GYKFL 346
170290998 262 EELRISDVYKQFEYAGRFLSRIPSGIKVIYIPGNHEPVRQAEPQPELQSDYlDILLDAnHNIVALPNPSMVKIG-SLSIL 340
18976390  489 IAHGRGIEDVVGSVPGLTHHKPGLPMVEL---LKMRHVAPMFGGKVPIAPDPEDLLVIEEVPDVVHMGHVHVYDAVVYRG 565
57641837  608 VAHGRGIEDVVDFVPNRSHHRPAEAMVEL---LKLRHIAPTFGNKVPIAPDPEDTLVIESVPDLFQAGHVHVMQYKTYNG 684
212224794 574 IAHGRGIEDVVSFIPNRTHHRPAEAMLDL---LKLRHLAPTFGEKVPIAPDPEDTLVIESVPDLFQAGHVHVMQYKIYNG 650
13542203  340 VYHGMSLNDMIELIPGANYDSIGKAIEAI---LVRRHLSPRYGGNTPLIPSSVDYHVIEEVPDIFITGHIHSHYIGNYKG 416
16081371  365 VYHGMSLNDMIELIPGANYDSIGKAIEAI---LVRRHLSPKYGGNTPMIPSAVDYHVIEEVPDIFITGHIHSHYIGNYKG 441
20095019  399 LFHGQSLDDIIIDHPD-AEHNPDGVRKAVklcLRARHLVPIYGGSVPIAPLPEDYLAIRKLPHVLAVGHTHVSAVEVWNG 477
48477541  345 IYHGMSLNDMIELVPGANYASVGSAIEEL---LKRRHLAPVYGGKTPIIPSKVDYHVIEKIPDIFITGHIHSHSLGNYHG 421
161527514 352 MFHGQSIDDIVKTTPGLSYDKPTNVMKHL---LRARHLSPIYGSQTPIAPEMQDLMVIEDIPDIFHVGHVHKAQLDMYKG 428
289596289 347 LYHGAAINDLVELIPGMNYEKIGSIMRNM---LEMRHLYPPYGGKVPIAPLKRDFLAIDLVPDVFVTGHVHAFTYEKYKD 423
170290998 341 LYHGRSLNAVMKHIPGLQPVNPQTVVEAMswiLRLRNLVPIYGEH-PISPEERDWLLIENPPNLFHTGHVHVYGVGDYRG 419
18976390  566 VQLVNSATWQAQTEFQKMVNIVPTPAKVPVVDIDTAkv------vKVLDFS 610
57641837  685 VFVINTGTWQAQTEFQKMVNIIPTPARVPIIDVETArl------rAVVRFD 729
212224794 651 VFLINTGTWQAQTEFQKMVNIVPTPARVPIIDVETArl------rAVVHFD 695
13542203  417 VRYVNSSTWQSQTEYQKMMNFNPKPSKLTLFDLYSRt-------vIVKDFD 460
16081371  442 VRYVNSSTWQSQTEYQKMMNFNPKPSKLTLFDLYSRs-------vIVKDFD 485
20095019  478 CNVISTATFQEQTEFQKKVGISPTVGRVIVLNMRRDeyenpkrrfTIVDLT 528
48477541  422 VRYVNSSTWQSQTEYQKMMNFSPNPSIATLFDLNSNn-------vIKMDFK 465
161527514 429 ILLVNSGSWQKQTPFQASVGMTPNPGIALLVNLKTFq-------vFHQNYN 472
289596289 424 VHIINASCWQAQTKYQKMMNFNPVPGKVALINFHTDe-------vKVLSF- 466
170290998 420 VKLVNSGTFENETPYIRSLGIEVTVGKVPVLNLENLe-------iKIMDFQ 463
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