4NOI,5I2D


Conserved Protein Domain Family
RNA_pol_A_CTD

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pfam03118: RNA_pol_A_CTD 
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Bacterial RNA polymerase, alpha chain C terminal domain
The alpha subunit of RNA polymerase consists of two independently folded domains, referred to as amino-terminal and carboxyl terminal domains. The amino terminal domain is involved in the interaction with the other subunits of the RNA polymerase. The carboxyl-terminal domain interacts with the DNA and activators. The amino acid sequence of the alpha subunit is conserved in prokaryotic and chloroplast RNA polymerases. There are three regions of particularly strong conservation, two in the amino-terminal and one in the carboxyl- terminal.
Statistics
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PSSM-Id: 427148
Aligned: 59 rows
Threshold Bit Score: 57.5511
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4NOI_B        268 NELENTKLLQNITDLNLSARSYNCLEKAGVVYIGELALXSVSELAGLKNLGKKSLDE---IKNIXE 330 Campylobacter jejuni subsp. ...
CAL59218      263 NNDEPIENDVDINQLGLSVRSLNALKRIGKTKASEVAAMTWEELEQTKNLGRKSLDE---IQECLK 325
jgi:Amet_2144  87 GHDGLKYIDIAIENLNLSVRAFNCLKSTSVDYYSQLIDVLDEELIAIPNMGRKTLLElehIKKTVQ 152
Q01V32         13 GDPKIVSLESAVEDLGLSVRTRNALRAIGCDTVENVLALDLGS--SVRGLGRKTKEE---LLVALE 73  Candidatus Solibacter usitat...
Q1IX99        261 YPADLDTPRVTLEGLGLTTRVLHSLKEEGIDSVDALCALSDRDLKKVPGIGERSLDE---IKQQLA 323 Deinococcus geothermalis DSM...
5I2D_L        245 pPEQEEELDLPLEELGLSTRVLHSLKEEGIESVRALLALNLKDLKNIPGIGERSLEE---IKEALE 307 Thermus thermophilus HB8
EAW45063      240 DD---PTAQIPIEELQLSVRAYNCLKRAQVNSVADLLDFTQEDLLEIKNFGQKSAEE---VVEALQ 299
A0T0K0        244 IE---PYTNIAIEELQLSVRAYNCLKKAQINTVGDLLQYSPEKLQELKNFGRKSADE---VFSTLK 303 Phaeodactylum tricornutum CC...
P60315        376 EV---DLRHVYVDQLRIPSKAYNSLKRANINTVSDLLDYTQDDLLSIPNFGRKSVDD---ILEALQ 435 Physcomitrium patens
P56762        265 ktKELAFQYIFIDQLELPPRIYNCLKKSNIHTLLDLLNNSQEDLIKIEHFHVEDVKK---ILDILE 327 thale cress
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