Conserved Protein Domain Family
methyltr_grsp

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TIGR04188: methyltr_grsp 
methyltransferase, ATP-grasp peptide maturase system
Members of this protein family are predicted SAM-dependent methyltransferases that regularly occur in the context of a putative peptide modification ATP-grasp enzyme (TIGR04187, related to enzymes of microviridin maturation) and a putative ribosomal peptide modification target (TIGR04186).
Statistics
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PSSM-Id: 275041
Aligned: 15 rows
Threshold Bit Score: 414.834
Created: 9-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
ZP_06577401   16 MAEDLAARGYLDDPGWRAAVEAVPRHRFV-PGFYlpTDERDGRGltrWQPVTAD-LDhg-rWLAAAYSDTTLITQFDGDE 92  Streptomyces gh...
ZP_04998400    5 LAGQLAAGGHLRTPPWREAVETVPRHEFLrGGFFdrVDLPGRPTa--WAPVMPDePL----WLERCYEDESLVTQIAGTI 78  Streptomyces sp...
ZP_06592247   36 LAARLAQSGALHTPTWRRAVESVPREAFLhPGVF----LPEPRGr--WRPFLADrSPea-eWTRLAYSDQSLVTQLDGSL 108 Streptomyces al...
ZP_05531079    7 LRHQLATAVPVENPAWRKALETVPRELFLgNGLF----QFDGRQ---WTPVHRDrTDpg-kWLGLVYQDTTWVTQVDGTT 78  Streptomyces vi...
ZP_05517097   12 LAEEVAAANPTLDSGWRDAVAVVPRELFLgAAAF----RPTGAG---WEPVRRAeVGed-eWLRMVYSDRTWVTQVEGED 83  Streptomyces hy...
ZP_06591364   11 LAEAIAADGELADPAWRDAAASVPRELFT-SSYF--EPVPGGPEt-rYRSVRPGdDG----WLPGIYTDRTLVTQLDGRV 82  Streptomyces al...
WP_012183425  12 FVAELEAGGVLSDAAWREAFTKVPRHVFL-PAFF--TSLPDGR----WQAMDQShPD----YWRLVYADTTLTTQLDATI 80  Salinispora are...
WP_012013654  12 LVHELTGHGWLTE-AWRTAFAAVPRHLFL-TRFF--RQTPDRSR---YEAVDVNdLGa----LELIYSDRVLPTQLDGDD 80  Salinispora tro...
WP_012184890  15 LVAQLHTTGHLTSPTVAGAFASVARHPFA-PAVY--DVNSHGQV---GDVLHATrPEhqdaYLAAVYGDEAIVTQIAED- 87  Salinispora are...
WP_011292232  12 LADKLAHDGKLRDPAWIKAFASIPRHLFL-PHIY--QPHPDGGF------TLAStPEe------LAYQDEGWTTQINGTF 76  Thermobifida fusca
ZP_06577401   93 PDwKHPA--ARYGGAPTSSSTLPSLVLRMWADAEVREGHTVLEIGTGTGYSTALACERLGSAGVTSIEVDARRLERAASA 170 Streptomyces gh...
ZP_04998400   79 AP-RDLR--GEITRAPTSSSTMPSLVVRMLEDLAVEAGHRVMEIGTGTGYSTALLCHRLGDDQVTTVEVDEEISAHAGAA 155 Streptomyces sp...
ZP_06592247  109 TP-DQATtpEPVPGVPTSSSTEPALVLRMLESLEVEEGQEVLEIGTGTGYSTALLCHRLGEDNVTTVDVDPGVARRADDA 187 Streptomyces al...
ZP_05531079   79 AV-DAT---GPVTGRPTSSSTLPSLIVRMLDVAGISEGHKVLEIGTGTGYSTAILCSRLSDNNVYSIEYDPGLAATAADH 154 Streptomyces vi...
ZP_05517097   84 AA-EAT---GAVSGSPTSSATLPSLVVRTAQVAELRPGQRVLEVGTGTGYSTAILCHRLGAGNVVSIEYDADLAARAAVH 159 Streptomyces hy...
ZP_06591364   83 RA-DEVTgdEPVAGSPSSSSTLPSLVLRMWRQLEAEDGQRVLEIGTGTGYSAALGAHRLGDARITSIEYDPVVAASAASA 161 Streptomyces al...
WP_012183425  81 HP-DPSV--GPVAGTGTSSSTQPGLMAAMLDALRVTGGERVLEIGTGTGYNAALLAHRLNAQDVTSVEVDARVADAARQR 157 Salinispora are...
WP_012013654  81 ARwDESRhhGPLAGVPTCSSTQPALMAVMLDALDVADGHRVLEVGTGTGYNAALLAHRLGSPLVTTVDIDAGLVRRARQS 160 Salinispora tro...
WP_012184890  88 -------------GRPTSSSTQPGVMAVMLEALDLQPGMTVLEIGTGTGYNAALLAHLLGDEAVTSVDIDPHLVTTATTA 154 Salinispora are...
WP_011292232  77 PT-PKDG--EPIQGQPTSSSSAPGLMAVMLEALDVTDGVRVLEVGTGTGYNAALLCHRLGDQHVVTVEVDPVLAEQAQQR 153 Thermobifida fusca
ZP_06577401  171 LHDCGHTPTLAVADGQYGYWPEAPFDRIVAACSFRAVPPALVAQTRPGGKILLTLS-GWLYGYARVLLTVAGDGTAEGRL 249 Streptomyces gh...
ZP_04998400  156 LGACGYAPHRVIGDGLAGHAAGAPYDRTVATCGIVDLPPSWIEQTRPGGVILATLG-GWMYASELARLTVHEDGTASGRF 234 Streptomyces sp...
ZP_06592247  188 LESIGVSTWTVTGDGLLGHPPRAPYDRVIATCAVRRVPYTWVRQTRPGGVILTTLG-SWPHGGGLAKVSVGADGTAEGRI 266 Streptomyces al...
ZP_05531079  155 IHAAGYHPTLITGDGLAGHKDDAEYDHIVATCAVRHIPPAWLYQVRVGGTITTTIS-GWMLASGLVRLTVQDDATATGRF 233 Streptomyces vi...
ZP_05517097  160 LSEAGCAPTLAVGDGLQGCRKHADYDAIIATCSVRSIPHSWFWQLNDGGSITTTVS-GWMLAAGMIRLVLDDEGTAHGRF 238 Streptomyces hy...
ZP_06591364  162 LAAAGYAPRLIVGDGLRGDLDGGPYDRLVATCAVRHIPLPWLHQVVPGGKILVTLS-GWSYASGLALLTVTAPGTATGRF 240 Streptomyces al...
WP_012183425 158 LVVAGYHLSVITGDGEQGWRPAAPYDRLIATVSVPAVPRAWLAQVRDGGAIVASLW-RDLGGAPLVRLEVDGD-TAQGFF 235 Salinispora are...
WP_012013654 161 LTSVGYAPTVAATDGEAGYPGNAPYDRIIAACSVPQVPTGWLAQSRPGGVILTSLH-REIGGGLLLRLTVDETGTASGHL 239 Salinispora tro...
WP_012184890 155 LHHAGYRPTVVAADGLAGYPARAPYDRLIATCSVRRVPAAWLRQAKPGGLVLANLS-Y-----GVVPLRVDDTGAGHGRF 228 Salinispora are...
WP_011292232 154 LAEVGYRPIVHVGDGADGYPPGAPYDRVIVTCALTSLPWKLIEQTRQGGVLVVPVWrGHLPAGLMLRLTATGGSLARGQV 233 Thermobifida fusca
ZP_06577401  250 LGGTVSFMPARAHAAPAFGnp---aH---WAAGPPGKAR-VARH-GPeRITAATEE-SFhLrflVQSAVPDTQLATV--- 317 Streptomyces gh...
ZP_04998400  235 LGGQISFMLARPQQPPPLG------V---LPDLDQGDEH-PALL-GA-DALNDWNT-RF-V---AQLAAPRTQRITLdrd 297 Streptomyces sp...
ZP_06592247  267 V-GPVSFMQARAQAQPPVTgd---lA---ARAAYADSER-EVRV-PP-TVLEEWTP-AF-L---AQLTVPDAQLVHArta 331 Streptomyces al...
ZP_05531079  234 HPDQISYMLARPHERPPR-------P---TFQQHPGHTR-ATRV-NP-ALLEDWTG-QF-L---AQLAAPSAELMT---- 291 Streptomyces vi...
ZP_05517097  239 TGDTITYMLARPHERPPS-------P---SFFRLDGDSR-STRL-DP-GLLEEWAG-RF-V---AQLAAPSAELMT---- 296 Streptomyces hy...
ZP_06591364  241 LPGHTSFMIARPHDRPPR-------P---TLTLLPGEER-ATRI-DP-AVVRTWTG-SW-V---AQLAVPAAERMG---- 298 Streptomyces al...
WP_012183425 236 LPQPGGFMPVRSANRAMAAl-----S---AATRQIGISR-TATV-PS-GVLHDDDA-GL-W---LALQVPEVTWLGFtpd 299 Salinispora are...
WP_012013654 240 LDDYGSFMPLRSCPTVRTSal---vR---AASQATGDRH-KTHL-PG-PLADDGEAwTA-L---VALLLPDVARLDLgrp 306 Salinispora tro...
WP_012184890 229 LPQVAAFIEARPADGPVGPtvadmvS---SCMGSTGTTS-PGHNrDV-ALFGDPCG-EF-W---WRLAEPSIYHCTLlpd 298 Salinispora are...
WP_011292232 234 LDAYGGFMPARNTPPADAVql---lHrhqAAADEGGTARtTSLT-TG-TSGEPW---AW-F---AALVVPDAVSLGTihd 301 Thermobifida fusca
ZP_06577401  318 GGVVH---LVDVVSGSTATLTPgggVGGGWQVREGGPVRLWECVERVLDAYDAAGRPGPETFTLCVHEDGQHL 387 Streptomyces ghanaensi...
ZP_04998400  298 GRTEHv--LIDVNAGSWAALTE---TNGAWTVRQGGPDRIWDAIEHHVNRWREHGAPELDRFTVTATPNGHTI 365 Streptomyces sp. Mg1
ZP_06592247  332 EGEQQrtyLFDPGRESFAEFVPgprNAAGWTVRQGGPVRLWDQVEETLLAWRDAGSPGVDAVRLRVTETAHHY 404 Streptomyces albus J1074
ZP_05531079  292 TGTGVi--LVDVATGSQAWTEP---AGGGWTVHQHGPLRLWDQVEDALTIWQDAGSPPHSDLGLTVDLDGTQR 359 Streptomyces viridochr...
ZP_05517097  297 TGSGIi--LRDVATGSQAWTEP---DGDGWTVHQHGPLHLWDQVEQALLLWRDAGAPDLTKFGMTATPFEQTV 364 Streptomyces hygroscop...
ZP_06591364  299 EGAAQi--LWDVSTGSQARTAPs--PGGGWTVVQRGPVRLWDRVEEAIAAWQAAGEPHQEAFGISVSAERQRV 367 Streptomyces albus J1074
WP_012183425 300 GGTDQv--WLFAPDGSWAMVE-----DATVHVEQYGPRNLWDEVEAAYDRWGATGQPRRDRLGLTVTGTGEHQ 365 Salinispora arenicola
WP_012013654 307 EGPVQ---WLVHPDGSWAYHDI-----STQTVEQGGPRRLWTEVEDLYSRWTAHGKPSRSHIGVTITPAGQQV 371 Salinispora tropica
WP_012184890 299 GEVVHc--LVDADTDSWARIHA---QGSTVTVTQGGPRRIWHAVTTACRRWDSAGRPTHDHLGLTVDRNGTHT 366 Salinispora arenicola
WP_011292232 302 DGPPR---HWLLTEDSWCYLTP---DG---RVVQGGRRHLWDEIEAAHSTWEQLGQPARHQCQVIIDPDGARL 365 Thermobifida fusca
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