4N6R


Conserved Protein Domain Family
Velvet

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pfam11754: Velvet 
Velvet factor
The velvet factor is conserved in many fungal species and is found to have gained different roles depending on the organizm's need, expanding the conserved role in developmental programmes. The velvet factor orthologues can be adapted to the fungal-specific life cycle and may be involved in diverse functions such as sclerotia formation and toxin production, as in A. parasiticus, nutrition-dependent sporulation, as in A. fumigatus, or the microconidia-to-macroconidia ratio and cell wall formation, as in the heterothallic fungus Fusarium verticilloides.
Statistics
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PSSM-Id: 463342
Aligned: 105 rows
Threshold Bit Score: 123.969
Created: 24-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4N6R_B        59 WSLQVVQQPIRARMCGFGDK---DRRPITPPPCIRL-------IVKDa---QTQKEV------DINS----LDSSFYVVM 115 Aspergillus nid...
XP_006679480  94 YFARIIQQPSQALAVGIYNNp-lSAHPIEPCVIVQLfkvtpdnILDD----------------SIDSm---PDWQHYIAH 153
XP_006683083 105 YQAYIVQQPVTTLACGISYIgpqPIVPIEPCLAVQL-------RLVSa--pQAIDKRhh----------ifLSSGSLIAH 165
EGF80181      69 YHAQVIQQPAYTRCSGLSNNg-aITCPIEPCISVQLhgva--------msgSSENQT------DVGI----PDIDCLIAQ 129
GAC75770      10 YKLVLVQQPTIGS--AFEDNl-lGRLGLAPPLIVEL-------QVFR------DGKI------SDAT----ADLPFLICQ 63 
Q5K9I1        87 FALTVEQEPVLGR--RKTEK---DRRPLGPAPIVRLravecrsADDDa--gVIEEEV------DAGT----LDAVNIVCA 149 Cryptococcus ne...
XP_003029052  58 AEIQEIQQPLLGR--KYASK---DRRPLDPPPVVRL-------RVFEavvpSPGSPY------PVREitstIDTSDYTCI 119
XP_001880119  43 VELEELQKAERGR--KYARV---DRRPLDPPPAVLL-------RVFEv--nRTDSGRqwereiKPES----IRNIGIMCT 104
EMD37395      37 AKLEELQKPVLGR--KYSDG---SGRPLDPPPVVRV-------RLFHi--dNPGTPDeheeelKCEE----IIDYGLTCY 98 
EMD37397      37 VRLEELQKPKLGR--KFTSS---NGRPIDPPPVVCI-------RLFRv--nNPGTSDenedelECEA----ILDLGLTCY 98 
4N6R_B       116 ADLWN--AD----GTHEVNLV----------------------------------------------------------- 130 Aspergillus nid...
XP_006679480 154 AFLSS--VNgkedQSNFIQTAllqhksepatsplskp-----------------------------------------eq 190
XP_006683083 166 AYLTS--VD----GTTDLSSFvrstqslitkkrrqsvptqqskksvasriplpaictptsftghldssstqanskstcfd 239
EGF80181     130 AYLTC--SN----GTSDLNYYsrtmartystamdh--------------------------------------------- 158
GAC75770      64 CSLLD---------------Eqgrvad----------------------------------------------------- 75 
Q5K9I1       150 ADLCApmVSqysaIEETSGVKllrgseh---------------------------------------------------- 177 Cryptococcus ne...
XP_003029052 120 ARMYS--------------------------------------------------------------------------- 124
XP_001880119 105 VDLFP---------------Vpe--------------------------------------------------------- 112
EMD37395      99 VDLFP--------------------------------------------------------------------------- 103
EMD37397      99 LDLFPi-------------------------------------------------------------------------- 104
4N6R_B       131 -------------KH-SATSPSIST--------------------AMSSSYPPPPHPTssd-------------ypASYQ 163 Aspergillus nid...
XP_006679480 191 etdrkssriqhktESsSVGQSASSLdg-----------------pGHSSKTRGRSKSKtgakv---------espaSTPS 244
XP_006683083 240 ghvdlldltfanpDSrTEASSAWSPap-----------------yNSSLSSQYSGTSStspms---------nlnkWVDK 293
EGF80181     159 sklqnddefksfiQNtSVTVANNARtp-----------------lIHSDATQRVTCQDeadqa---------hlgfYSQD 212
GAC75770      76 --------mvdqrVGsASQQSQEARtapaavsavprrgrsvrnkiSHRGGLADGTVTPlsldsteastssasedtlTPGT 147
Q5K9I1       178 -------qphgenDTsSANFPGATSse-----------------qASSGPSTQAQKARdqaat---------sevdPASL 224 Cryptococcus ne...
XP_003029052 125 -----------------ARSPCIVPap-----------------pPPSGGYLCQQQAPfpnhd---------ldtdVWPG 161
XP_001880119 113 ------------sLLsSDSSSSTSQyy-----------------pRASMSTGADPRSAaplt----------yfplHPYT 153
EMD37395     104 --------------IaSASRASGDIhv-----------------pDASVSSPTQSMFPqgnte---------avnvVPVR 143
EMD37397     105 --------------------------------------------pSSSGASRGSVQPPpgess---------rhdeIPPR 131
4N6R_B       164 TNPYGQPVGQPVGQPVGyagvgnyyggstqlqyqnaypnpqaqyyqpmyggmaqPQMPAAQPVTPgpGGMFTRNLIGCLS 243 Aspergillus nid...
XP_006679480 245 MQHSIAQLSAPTPQHTAlakqllnp----------------------pqgqdkpTNTGLTLLDGP--VGNVENSLCGTLV 300
XP_006683083 294 SYADSKESMARSRSSTYdtseeh-------------------------saktwkDVTLSFLSFNY--AQKPMRSLYGRHV 346
EGF80181     213 VDHHTSPHSPPCIVDDTtylpdtdypqsqvpvdfashttppntiqsisdksewrDITSHVLVNRS--VQAQIPTLCGNQT 290
GAC75770     148 GESSATQLSGRN-------------------------------------------------------SPQIVRMLYGTLA 172
Q5K9I1       225 GDRSLAEDVVRGEKAAKewkrpkssge------------------mssgsatetGSAHRGGAGRG--AAVPERNLYGNLH 284 Cryptococcus ne...
XP_003029052 162 PSGYANGPMTPPRL--------------------------------------------FHPTPQE--DRDLTDKLVGGKV 195
XP_001880119 154 TQDVHAEEAAMASFHIPrrqplvrhl-------------------npnevpkdvVFRLGNHLVTE--SSKLTPALVGEKF 212
EMD37395     144 PQATTAPPSDVIAF-------------------------------------------FDKHAITE--SSNHTDWLIGKRF 178
EMD37397     132 TEDRTAPPLDVITI--------------------------------------------NGHTITE--GASCTDQLVGIR- 164
4N6R_B       244 ASAYR---LYDTEDK--IGVWFV----LQD-------------LSVRTEGIFRLKFSFVNVGKsvsdlp----qsdiaeV 297 Aspergillus nid...
XP_006679480 301 SASYLchdLLGC-----NGVFFC----FPD-------------LSIRINGVFKLRIAISKLPIlgnliaksinkshhsaT 358
XP_006683083 347 AEASMvmgLDDV-----LGVFFF----FPD-------------LGVRIPGTFRIKVVISDISScts-----------rvD 393
EGF80181     291 AAADIatdLDNN-----RGVFFF----FPD-------------LGIRIPGKFKIRIIISKIQLde------------sqR 336
GAC75770     173 AGPQQyisPN---ADeeEKAYFF----FPE-------------LSIRTPGRFKIICTLLRLSL----------------- 215
Q5K9I1       285 VGGVK---VPDLEGK--MGVWFL----FTD-------------LCVRQEGSYSLRFRCYDITA----------------- 325 Cryptococcus ne...
XP_003029052 196 VTARTi------eLDgvQMSVFP----FTD-------------LSVQLEGEFYLQYSVFDLAGmc-------------lI 239
XP_001880119 213 VEPTLv------eHKgkKALVFV----FGD-------------LAIQREGSFILRYRALDIFT----------------- 252
EMD37395     179 VEACMi------qYHgeQMLVFV----FPA-------------IAVQLQGIFTLRYRAFSLFA----------------- 218
EMD37397     165 -------------------IWFIphpnLTDnwvitsiitlpqaIAAQLKGAFVLRYRSFSLLA----------------- 208
4N6R_B       298 INK--GTAPILASTFSEPFQVFSAKKFPGVIESTPLSKVFANQGIKIPI-RK-DG 348 Aspergillus nidulans
XP_006679480 359 DTEmgSEGCIIATTISDAFTSHTSATWQGHSEWTNISDHFSNQGVNIIRfKTrSK 413
XP_006683083 394 PKQacKSGTVLAEVLSDPFVSHTSATWGGHYKPTDISKHFTKQGVHIPFfKQrKS 448
EGF80181     337 DEPisAKNIVLAEVVTNAFISHSPNSWTGHHAPTQLSKHFSRQGVRIPLfKTrRN 391
GAC75770     216 PGMeaAEVGSLASVETQTFEVVKRTDYSA-PYITDISRHFARQGVPLLLppgvsa 269
Q5K9I1       326 VEEegLPVAQLVECRSQPFRIYSPRQIPMLPKLTELAEHFARLGFKLNT-RKnDR 379 Cryptococcus neoformans
XP_003029052 240 PGSmgGTSPCRASCTGGTFTMYPTKEAPTLPPSTKITKALYDAGIRVTY-RKqPR 293
XP_001880119 253 LSSgsNHPPILAELYGGSFKVYSTREFPGLEPSTELTRNFSNHGVRVTL-RDaER 306
EMD37395     219 KAAgeHGTPIIAECYSWPFHVYSNKDFPGFRASTELTKHLAALGIRTRV-REhDQ 272
EMD37397     209 RVAgeHGTPVIAECFSEPFTIYSCKRFPGFPVSTELTKYLSTQGIRTRV-REqPE 262
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